LOCUS       NM_001304964            1172 bp    mRNA    linear   PRI 17-APR-2022
DEFINITION  Homo sapiens GLIPR1 like 1 (GLIPR1L1), transcript variant 1, mRNA.
ACCESSION   NM_001304964 XM_005268771
VERSION     NM_001304964.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1172)
  AUTHORS   Gibbs GM, Lo JC, Nixon B, Jamsai D, O'Connor AE, Rijal S,
            Sanchez-Partida LG, Hearn MT, Bianco DM and O'Bryan MK.
  TITLE     Glioma pathogenesis-related 1-like 1 is testis enriched,
            dynamically modified, and redistributed during male germ cell
            maturation and has a potential role in sperm-oocyte binding
  JOURNAL   Endocrinology 151 (5), 2331-2342 (2010)
   PUBMED   20219979
REFERENCE   2  (bases 1 to 1172)
  AUTHORS   Ren C, Ren CH, Li L, Goltsov AA and Thompson TC.
  TITLE     Identification and characterization of RTVP1/GLIPR1-like genes, a
            novel p53 target gene cluster
  JOURNAL   Genomics 88 (2), 163-172 (2006)
   PUBMED   16714093
REFERENCE   3  (bases 1 to 1172)
  AUTHORS   Zhang Z and Henzel WJ.
  TITLE     Signal peptide prediction based on analysis of experimentally
            verified cleavage sites
  JOURNAL   Protein Sci 13 (10), 2819-2824 (2004)
   PUBMED   15340161
REFERENCE   4  (bases 1 to 1172)
  AUTHORS   Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J,
            Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D,
            Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS,
            Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M,
            Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J,
            Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods
            K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard
            A, Wood WI, Godowski P and Gray A.
  TITLE     The secreted protein discovery initiative (SPDI), a large-scale
            effort to identify novel human secreted and transmembrane proteins:
            a bioinformatics assessment
  JOURNAL   Genome Res 13 (10), 2265-2270 (2003)
   PUBMED   12975309
  REMARK    Erratum:[Genome Res. 2003 Dec;13(12):2759]
REFERENCE   5  (bases 1 to 1172)
  AUTHORS   Harrington JJ, Sherf B, Rundlett S, Jackson PD, Perry R, Cain S,
            Leventhal C, Thornton M, Ramachandran R, Whittington J, Lerner L,
            Costanzo D, McElligott K, Boozer S, Mays R, Smith E, Veloso N,
            Klika A, Hess J, Cothren K, Lo K, Offenbacher J, Danzig J and Ducar
            M.
  TITLE     Creation of genome-wide protein expression libraries using random
            activation of gene expression
  JOURNAL   Nat Biotechnol 19 (5), 440-445 (2001)
   PUBMED   11329013
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY358731.1, BC014603.1, BG196035.1 and AC121761.4.
            
            On May 17, 2019 this sequence version replaced NM_001304964.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.307952.1, BQ435571.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000378695.9/ ENSP00000367967.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-609               AY358731.1         32-640
            610-610             BC014603.1         602-602
            611-851             AY358731.1         642-882
            852-1002            BG196035.1         166-316
            1003-1172           AC121761.4         40542-40711
FEATURES             Location/Qualifiers
     source          1..1172
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q21.2"
     gene            1..1172
                     /gene="GLIPR1L1"
                     /gene_synonym="ALKN2972; PRO7434"
                     /note="GLIPR1 like 1"
                     /db_xref="GeneID:256710"
                     /db_xref="HGNC:HGNC:28392"
                     /db_xref="MIM:610395"
     exon            1..233
                     /gene="GLIPR1L1"
                     /gene_synonym="ALKN2972; PRO7434"
                     /inference="alignment:Splign:2.1.0"
     CDS             60..788
                     /gene="GLIPR1L1"
                     /gene_synonym="ALKN2972; PRO7434"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; GLIPR1-like protein 1; GLI pathogenesis related
                     1 like 1"
                     /codon_start=1
                     /product="GLIPR1-like protein 1 isoform 1 precursor"
                     /protein_id="NP_001291893.1"
                     /db_xref="CCDS:CCDS76578.1"
                     /db_xref="GeneID:256710"
                     /db_xref="HGNC:HGNC:28392"
                     /db_xref="MIM:610395"
                     /translation="MALKNKFSCLWILGLCLVATTSSKIPSITDPHFIDNCIEAHNEW
                     RGKVNPPAADMKYMIWDKGLAKMAKAWANQCKFEHNDCLDKSYKCYAAFEYVGENIWL
                     GGIKSFTPRHAITAWYNETQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMCPNLG
                     GASTAIFVCNYGPAGNFANMPPYVRGESCSLCSKEEKCVKNLCRTPQLIIPNQNPFLK
                     PTGRAPQQTAFNPFSLGFLLLRIF"
     exon            234..479
                     /gene="GLIPR1L1"
                     /gene_synonym="ALKN2972; PRO7434"
                     /inference="alignment:Splign:2.1.0"
     exon            480..580
                     /gene="GLIPR1L1"
                     /gene_synonym="ALKN2972; PRO7434"
                     /inference="alignment:Splign:2.1.0"
     exon            581..669
                     /gene="GLIPR1L1"
                     /gene_synonym="ALKN2972; PRO7434"
                     /inference="alignment:Splign:2.1.0"
     exon            670..696
                     /gene="GLIPR1L1"
                     /gene_synonym="ALKN2972; PRO7434"
                     /inference="alignment:Splign:2.1.0"
     exon            697..1172
                     /gene="GLIPR1L1"
                     /gene_synonym="ALKN2972; PRO7434"
                     /inference="alignment:Splign:2.1.0"
     regulatory      825..830
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GLIPR1L1"
                     /gene_synonym="ALKN2972; PRO7434"
                     /note="hexamer: AATAAA"
     polyA_site      854
                     /gene="GLIPR1L1"
                     /gene_synonym="ALKN2972; PRO7434"
                     /note="major polyA site"
     regulatory      970..975
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GLIPR1L1"
                     /gene_synonym="ALKN2972; PRO7434"
                     /note="hexamer: AATAAA"
     polyA_site      1006
                     /gene="GLIPR1L1"
                     /gene_synonym="ALKN2972; PRO7434"
                     /note="major polyA site"
ORIGIN      
        1 gccccagccg ttactggtcc gcgcagtcag ggcatcctcc gcatcctcca catccttcca
       61 tggctctgaa gaataaattc agttgtttat ggatcttggg tctgtgtttg gtagccacta
      121 catcttccaa aatcccatcc atcactgacc cacactttat agacaactgc atagaagccc
      181 acaacgaatg gcgtggcaaa gtcaaccctc ccgcggccga catgaaatac atgatttggg
      241 ataaaggttt agcaaagatg gctaaagcat gggcaaacca gtgcaaattt gaacataatg
      301 actgtttgga taaatcatat aaatgctatg cagcttttga atatgttgga gaaaatatct
      361 ggttaggtgg aataaagtca ttcacaccaa gacatgccat tacggcttgg tataatgaaa
      421 cccaatttta tgattttgat agtctatcat gctccagagt ctgtggccat tatacacagt
      481 tagtttgggc caattcattt tatgtcggtt gtgcagttgc aatgtgtcct aaccttgggg
      541 gagcttcaac tgcaatattt gtatgcaact acggacctgc aggaaatttt gcaaatatgc
      601 ctccttacgt aagaggagaa tcttgctctc tctgctcaaa agaagagaaa tgtgtaaaga
      661 acctctgcag gactccacaa cttattatac ctaaccaaaa tccatttctg aagccaacgg
      721 ggagagcacc tcagcagaca gcctttaatc cattcagctt aggttttctt cttctgagaa
      781 tcttttaatg tcatttatat acaaaagaaa ttctcaaatg ttaaaataaa ggaatagttt
      841 attgcttaat ataacttatc atcactttgc ttctttactg aatcttctac actcttgcct
      901 gatacctaaa tttaatgttt gtttttaact caaaaaatgt actgtagtat ggaaaatgga
      961 tagcagtaga ataaagtctt aagattattt tttaattaca aatccatatg tgtatcaaaa
     1021 gtgttccact ctttaatttt ctaatgagaa tggattatca ttttagttat agtacattta
     1081 gagaactaaa gacttttcac atatcaaata gtttccttag ataccaatag tttcctttat
     1141 gaataccatc aacatcattc agaaacaaaa tg
//
