LOCUS       XM_047435080            7306 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens gap junction protein gamma 1 (GJC1),
            transcript variant X6, mRNA.
ACCESSION   XM_047435080
VERSION     XM_047435080.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7306
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..7306
                     /gene="GJC1"
                     /gene_synonym="CX45; GJA7"
                     /note="gap junction protein gamma 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 5
                     mRNAs, 12 ESTs, 264 long SRA reads, 12 Proteins, and 86%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 14 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:10052"
                     /db_xref="HGNC:HGNC:4280"
                     /db_xref="MIM:608655"
     CDS             410..1600
                     /gene="GJC1"
                     /gene_synonym="CX45; GJA7"
                     /codon_start=1
                     /product="gap junction gamma-1 protein isoform X1"
                     /protein_id="XP_047291036.1"
                     /db_xref="GeneID:10052"
                     /db_xref="HGNC:HGNC:4280"
                     /db_xref="MIM:608655"
                     /translation="MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIY
                     YDEQSKFVCNTEQPGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKM
                     EHGEADKKAARSKPYAMRWKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKP
                     KHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKI
                     DCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYN
                     YPFTWNTPSAPPGYNIAVKPDQIQYTELSNAKIAYKQNKANTAQEQQYGSHEENLPAD
                     LEALQREIRMAQERLDLAVQAYSHQNNPHGPREKKAKVGSKAGSNKSTASSKSGDGKT
                     SVWI"
     polyA_site      7306
                     /gene="GJC1"
                     /gene_synonym="CX45; GJA7"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gtccccaggc gcgcggctcc caaatcggga gggaaacggc tcgggggtgt cctgggccgc
       61 ggaggtgtcg ggcgacggtc ggggagcccg gacagaagcg gcgcgcactc ggcggcgccc
      121 cggcggtgcc gacaactacc cgggcggtta ggggcgcagg gcggagccgg gccgcccctc
      181 gccgcccggg ctcttcgcgg gctgctcttt gtctccccga cctcgatccc tgcgtctccg
      241 gcggcgtgcg ggctcgtctg aggcttcccg catctccccg ctggaactcc tgcctcccgg
      301 gggttagagg aggagggaat ctggaaaaat tgcaatcaaa acatcatttc tctaagaaaa
      361 ttttgggtaa ccgaagttct ggacaacagg gcataccaat tcaatcacca tgagttggag
      421 cttcctgact cgcctgctag aggagattca caaccattcc acatttgtgg ggaagatctg
      481 gctcactgtt ctgattgtct tccggatcgt ccttacagct gtaggaggag aatccatcta
      541 ttacgatgag caaagcaaat ttgtgtgcaa cacagaacag ccgggctgtg agaatgtctg
      601 ttatgatgcg tttgcacctc tctcccatgt acgcttctgg gtgttccaga tcatcctggt
      661 ggcaactccc tctgtgatgt acctgggcta tgctatccac aagattgcca aaatggagca
      721 cggtgaagca gacaagaagg cagctcggag caagccctat gcaatgcgct ggaaacaaca
      781 ccgggctctg gaagaaacgg aggaggacaa cgaagaggat cctatgatgt atccagagat
      841 ggagttagaa agtgataagg aaaataaaga gcagagccaa cccaaaccta agcatgatgg
      901 ccgacgacgg attcgggaag atgggctcat gaaaatctat gtgctgcagt tgctggcaag
      961 gaccgtgttt gaggtgggtt ttctgatagg gcagtatttt ctgtatggct tccaagtcca
     1021 cccgttttat gtgtgcagca gacttccttg tcctcataag atagactgct ttatttctag
     1081 acccactgaa aagaccatct tccttctgat aatgtatggt gttacaggcc tttgcctctt
     1141 gcttaacatt tgggagatgc ttcatttagg gtttgggacc attcgagact cactaaacag
     1201 taaaaggagg gaacttgagg atccgggtgc ttataattat cctttcactt ggaatacacc
     1261 atctgctccc cctggctata acattgctgt caaaccagat caaatccagt acaccgaact
     1321 gtccaatgct aagatcgcct acaagcaaaa caaggccaac acagcccagg aacagcagta
     1381 tggcagccat gaggagaacc tcccagctga cctggaggct ctgcagcggg agatcaggat
     1441 ggctcaggaa cgcttggatc tggcagttca ggcctacagt caccaaaaca accctcatgg
     1501 tccccgggag aagaaggcca aagtggggtc caaagctggg tccaacaaaa gcactgccag
     1561 tagcaaatca ggggatggga agacctccgt ctggatttaa tcctggcggg cttaaaacct
     1621 gtgcttttca tagtttatgg aacgatttca gatgtgtaag gagactgaag aggagatacc
     1681 agtttttagt cttggaaagc aagttcacag tagaaggagg ttgagatctt tcttttatgt
     1741 gagaaatctt tgaatctcat tcatgcgatc agagttgtag ccaatttttg aaaaccttat
     1801 tttcaaagga aataaatgat tcactgtagg attcctttaa atatcaagca tcaccagtat
     1861 atgctttgat ggtatatgta tataacttaa agttctttca aaagcctgat acagaaacgt
     1921 gtccccagtt tggtagcaat gtggaaaacc tggctagaga tgatatggag ctgtccctca
     1981 gaaagcaaag ccatgcctgg aatccctaat aggctgctta gttgtgaacc tgtttgattt
     2041 gccttaagcc tctatccaga aacctgcccg cttccgtctg gttaagaagc cagtggtgga
     2101 tattttcttt gttaacatta gaaatgcaaa cattcccttg tcaaccaaga atactcaaag
     2161 ctacttgtat tggaaatggc agaaggccta aatccaaatt tcttattttt tataatttac
     2221 catagaagtt ttgtgattaa attcttactt ctgccagtgg aggtttatgc ctgaaaggtc
     2281 atggggtcct gtctgtaaat agacctaaag agaagtgcag tatttattct ttgtaggcat
     2341 aatgtgtttg tcactgacaa gcattcatgt tcatcccact agtcttttat tgcagtcttt
     2401 tattgtcatt ttcagcctta tgttggagag ctttgctttc tcatcatgtt cacattgtct
     2461 taagttttgt gagcttctga gaaagagctt ggtaaaggtt taaaggggac tttgttccac
     2521 cagggagcat tttatttggg cgtctcaccc ttttctaatg aaagctgttg taagccacct
     2581 ctgacttgga aattctgaaa gtatgaatat tttttatatc ttaattgtaa aatgccagtt
     2641 ctccattatt tagatgaata gtagaacact gcaccctttg tgcagtgttt ttgtttctct
     2701 actgcattcc tacccccacc aaaaaaaaga aacttaagga aatttttttt tgagacaggg
     2761 tctccctctt tcacccaggc tggagtgcag cagcatgatc tcagctcact gcagcctctg
     2821 cctcccaggc tcaagcaatc attccacctc agcctcttga ttagctggga ctacaggcat
     2881 gtgccaccat actcggctaa ttctgtttta aaaatttttt ttgtagagat gaggtctcac
     2941 tatgttaccc aggctggtct cgaacttttg ggttcaagtg atcctcccgc ctcagcctct
     3001 caaagtgtta gtattatagg tgtgagccac catgcccagc ctagaaaatt taaccttatc
     3061 ttttagccat tcatttactt ttatttgctt ttttaaaaaa aaatctttaa attttagcct
     3121 agagaagcac ctcaggaact ctaaacatct taggcaaaaa ttaaactcag gtgagactga
     3181 aggagaaatt tcagaaatac acatgtacct catgggtaat taatagacat gcacagtttc
     3241 cttcaaatca aatgtttaat aaggaaattc atataattcc aagaaaacag gcaaaatttg
     3301 gaatacataa gcctagctaa gataaagaac taccagttaa ttcttaacat cactggagct
     3361 tccagcaggt tttttaattg aaggacaaaa agtgtccata catttgtgtt atctcttcag
     3421 agcctgaggg agaagagagt ggctttgccc agtggaaagg ctggggattt gagaatgata
     3481 cagggggaag gagtcaagca gaaatgccag gaagaaccag gcaaagacat ttggcgccag
     3541 aagcatccac ttaatttctg tgaagagtgc ccctggtgtt tcatcttggc ctgttttgat
     3601 gagaatgtta tcttttgtgt ctggataacg cgtcagcttc ttaaagtaca tataaagata
     3661 ttctgtcacc tccccacatg cacacacttt taaaatctat ttttattctc ttgctaaagt
     3721 tgtaattatg tcaagaattt tccagctcta actgccttct tagtacatgt ctttctgcct
     3781 ttgaagcata tgagtttgcc aaagtcattc tcccctaatg acatattgtg gacttacatt
     3841 aagaaaatgg gccaggcgcg gtggctcaca cctgtaatcc cagcacttta ggaggcccag
     3901 gcgggtggat tacctgaggt caggagttca agaccagact ggtcaacatg gtgaaactcc
     3961 atctctacta aaaatacaga aattagccag gagtgctggg tggacgcctg caatcccagc
     4021 tacttgggag gttgaggcag gagaattgct tgaacccagg aggcagaggt tgcagtgagc
     4081 tgagatcata ccattgcact ccagcctgca agacagagtg aaactcttgt ctcaaaaaaa
     4141 aaaaaagaaa aaaagaaagt gagcctgttg atgtctagct aacccattgg tggagtctgc
     4201 attgaatctg taagaatatt gttctggatc atgcaggtgg gatttgtata aaaagcctgt
     4261 ccaacattta gttctcactc gcatcagaat catactgttt tgaattgcca tataagacat
     4321 gctccatcat gacacttgct tctcctccaa atacaagttg agtgcttagt ccttcacctg
     4381 ctagaatcag gatacaatca acatgattat gttccttaac acacttggat ttatgcagat
     4441 gtggtgtgtc ctttgctctt ttttttctta agacagagtc ttgctcttgt cgctcaggct
     4501 ggagtgcagt ggtgtgattt cggctcactg caacctccgc ctcctgggtt caagcgattc
     4561 tcctgcctca gcctcccgag tagctgggat tacaggcacc accaccatac caggctgatt
     4621 ttttttgtat ttttaatata gacagggctt catcatgttg gccaggctgg caggctggtc
     4681 tcgaactcct cacctcgtga tccgcccacc tcagcttccc aaagtgctgt gattacaggc
     4741 gtgagccacc gcgcctggcc tgctcttaaa acccgttatt cagaagattt gtaaaagaaa
     4801 taggcttttt tttttttttt ggttaattca aacgagggga aaattagata gcattttccc
     4861 ctaaagaaat gttaatgttc attttgtggc tttgttttca agtttcagga gccatgtaca
     4921 tctcagaagt gttacgaagt gattagaaaa ggcctctggt aaaagacctt caaggaccaa
     4981 ccattattat tggtcacttg tttgaacttg gcgcttaaaa aaaaagttgg actgtgatgc
     5041 tttggtgctc tttatcacag acatcagtga tggtctgaaa cactctctag cagtttatac
     5101 gaagaatgga cttacatgtt atcagttaca ctcatgattt actcgttcag cttctacaag
     5161 tccatacttt atgctgtctc atttaagaga cagtccactt ctgaaaataa aatcgatagt
     5221 tgatgataca tttttggcta gccagctttc tgtaaaaggc aagtatgtta gacatgcaca
     5281 gtttccttca aatcaaatgt ttaataaggt acttcaagaa acgccttttt aaaaatcaaa
     5341 ggttttggcc aggcatggtg gctcacgcct gtaatcccag cactttggga ggccaaggtg
     5401 ggcgaatcac aaggtcagga gtttgagacc agcctggcca acatggtgaa accccgtctc
     5461 tactaaaaat accaaaaatt agccgggcgt ggtggtgggt acctgtaatc ccagctactc
     5521 aggaggctga gatgagaatc acttgatccc aggaggtaga ggttgcagtg agccgagatt
     5581 gcgccattgc acttcagcct gggcaacgag tgaaactctc aaaaaaaaat tcatagtaat
     5641 aataaagtcc ctgcatgcag tttggaaata aaatttaaac tcatttatgt gtaataaata
     5701 tgtaataatt cacagtcacc atcaaatgtt ggaatcattg aattgcatac ttgtactcat
     5761 tccggccaca tcatgaagtg tttaaagatt tgtatttgct gttgtcccta tgtagttcta
     5821 ttgatgtttg gttttgtttt ttggggtttg ttttgagccc aggctagagt gcaatggcac
     5881 aatctcaact cactacagcc tggacctcct tggctcaagc agtcctccca cttcagcctc
     5941 ccaagtagct ggtctgcaag tgctcaccac cacacctggc taatttttgt attttttgta
     6001 gagacagagc tctcactatg ttgcctagac tggtctcaaa ctcctgggcc caagcaatcc
     6061 tcccatcaca gcctccgaag gtgctgggat tacaggcata agccactgtg cccagcctgt
     6121 ttttaataat gatattaagt gggtttggtt catgtgttat taatcagtgt taataatcgt
     6181 actttttttt ttttttaaaa gaaaccatgg tattctaaaa tcaggagtcc aaataaaaga
     6241 aagttctcgg ctgtgcatgg tggctaacac ctgtaatccc agcactttgg gaggctgagg
     6301 tgggtggatc actagaggtc aggagtttga aacaagcctg gccaacatgg taaaaccccc
     6361 tctctactaa aaatacaaaa attagccggg catggtggtg cacacctgta atcccagcta
     6421 ctcgggatgt tgaggcatga gatttccttg aacctggaag gcagaggttg ctgtgagccg
     6481 agatcgcgcc actgcactcc agcctgggtg acagagtaag actgtcgcca aaaaagagga
     6541 aaaaagttat ccagtgcagt ttctacagag ataaaagaag taatagttct ggctgggtgt
     6601 ggtggcttat gcctgtaatc ccaacacttt gggaggccaa ggcaggtgga tcacatgagg
     6661 tcaggagttc gagaccagcc tggccaacat ggcaaaactg tctctactaa aaatataaaa
     6721 attaggtatg gtggcacgtg cctgtactta cagctacttg ggaggctgag gcatgagatg
     6781 acaatctctt gaacccagga ggcggaggtt gcagtgagct gagattgcac cactgcactc
     6841 cagcttgggt gatggagtga gactcaaata aaaaaggtac tagttctgca tttcagagtt
     6901 ggcttgttga accaggctat atgcttccaa gatttaaatg tttttctgta ttatactctc
     6961 aattgtgttt taaaaaaatc tcttacagaa atctctacct caggcactaa gtgttatgac
     7021 atgggtagca tattgatatt gaaaacttag ctaggacttc cagcctttta agataattta
     7081 aatgtaaaat taaatggtta accagcaatc taatgtcatg tggtgtgcag tttggatatt
     7141 gcatgaacag ctaaggaatc acctgttcta gtgccaaaga tcactcattg ctaattttgt
     7201 tctgtacagc ttatgtaata ttttcatggt ggagacggac tctgtgtgct cagggccttg
     7261 tctctaggaa gattttgtca attccaaata cagttttgaa gattca
//
