LOCUS       XM_024450526            7490 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens gap junction protein gamma 1 (GJC1),
            transcript variant X3, mRNA.
ACCESSION   XM_024450526
VERSION     XM_024450526.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7490
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..7490
                     /gene="GJC1"
                     /gene_synonym="CX45; GJA7"
                     /note="gap junction protein gamma 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 6
                     mRNAs, 14 ESTs, 473 long SRA reads, 12 Proteins, and 87%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 6 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:10052"
                     /db_xref="HGNC:HGNC:4280"
                     /db_xref="MIM:608655"
     CDS             121..1311
                     /gene="GJC1"
                     /gene_synonym="CX45; GJA7"
                     /codon_start=1
                     /product="gap junction gamma-1 protein isoform X1"
                     /protein_id="XP_024306294.1"
                     /db_xref="GeneID:10052"
                     /db_xref="HGNC:HGNC:4280"
                     /db_xref="MIM:608655"
                     /translation="MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIY
                     YDEQSKFVCNTEQPGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKM
                     EHGEADKKAARSKPYAMRWKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKP
                     KHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKI
                     DCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYN
                     YPFTWNTPSAPPGYNIAVKPDQIQYTELSNAKIAYKQNKANTAQEQQYGSHEENLPAD
                     LEALQREIRMAQERLDLAVQAYSHQNNPHGPREKKAKVGSKAGSNKSTASSKSGDGKT
                     SVWI"
ORIGIN      
        1 gccatgtgaa aagagaagct caaaagggaa tctggaaaaa ttgcaatcaa aacatcattt
       61 ctctaagaaa attttgggta accgaagttc tggacaacag ggcataccaa ttcaatcacc
      121 atgagttgga gcttcctgac tcgcctgcta gaggagattc acaaccattc cacatttgtg
      181 gggaagatct ggctcactgt tctgattgtc ttccggatcg tccttacagc tgtaggagga
      241 gaatccatct attacgatga gcaaagcaaa tttgtgtgca acacagaaca gccgggctgt
      301 gagaatgtct gttatgatgc gtttgcacct ctctcccatg tacgcttctg ggtgttccag
      361 atcatcctgg tggcaactcc ctctgtgatg tacctgggct atgctatcca caagattgcc
      421 aaaatggagc acggtgaagc agacaagaag gcagctcgga gcaagcccta tgcaatgcgc
      481 tggaaacaac accgggctct ggaagaaacg gaggaggaca acgaagagga tcctatgatg
      541 tatccagaga tggagttaga aagtgataag gaaaataaag agcagagcca acccaaacct
      601 aagcatgatg gccgacgacg gattcgggaa gatgggctca tgaaaatcta tgtgctgcag
      661 ttgctggcaa ggaccgtgtt tgaggtgggt tttctgatag ggcagtattt tctgtatggc
      721 ttccaagtcc acccgtttta tgtgtgcagc agacttcctt gtcctcataa gatagactgc
      781 tttatttcta gacccactga aaagaccatc ttccttctga taatgtatgg tgttacaggc
      841 ctttgcctct tgcttaacat ttgggagatg cttcatttag ggtttgggac cattcgagac
      901 tcactaaaca gtaaaaggag ggaacttgag gatccgggtg cttataatta tcctttcact
      961 tggaatacac catctgctcc ccctggctat aacattgctg tcaaaccaga tcaaatccag
     1021 tacaccgaac tgtccaatgc taagatcgcc tacaagcaaa acaaggccaa cacagcccag
     1081 gaacagcagt atggcagcca tgaggagaac ctcccagctg acctggaggc tctgcagcgg
     1141 gagatcagga tggctcagga acgcttggat ctggcagttc aggcctacag tcaccaaaac
     1201 aaccctcatg gtccccggga gaagaaggcc aaagtggggt ccaaagctgg gtccaacaaa
     1261 agcactgcca gtagcaaatc aggggatggg aagacctccg tctggattta atcctggcgg
     1321 gcttaaaacc tgtgcttttc atagtttatg gtaagcagca gctcactgaa taatgacttc
     1381 cattgagtaa acatttggct ctggttatct tcagggatgc tgttggctca tgatccaagc
     1441 tcaggggact ctggaggcgg ggctgggctg agggagagaa agggaaacac agtgttccca
     1501 ggcacatgtt cttagcaata atacagttgc agaactttac atttgtgtct tccagatctg
     1561 gagaagaaca gacatattta aatcattctt gttgaacagt ttttgtatgt acagtattat
     1621 ggtacttttt tttttttagt atgagaactt tttttgtatt tgtacattga actgctgtag
     1681 ttatactttt atattaaagg ggaaaaagtc cttataaata atgcctatta ggctagtgct
     1741 attactttgt tcagcaaatt ctaccctggc tttagagttt ttaatagatg ctacacctaa
     1801 taaaagtgcc tctcatattg caggaacgat ttcagatgtg taaggagact gaagaggaga
     1861 taccagtttt tagtcttgga aagcaagttc acagtagaag gaggttgaga tctttctttt
     1921 atgtgagaaa tctttgaatc tcattcatgc gatcagagtt gtagccaatt tttgaaaacc
     1981 ttattttcaa aggaaataaa tgattcactg taggattcct ttaaatatca agcatcacca
     2041 gtatatgctt tgatggtata tgtatataac ttaaagttct ttcaaaagcc tgatacagaa
     2101 acgtgtcccc agtttggtag caatgtggaa aacctggcta gagatgatat ggagctgtcc
     2161 ctcagaaagc aaagccatgc ctggaatccc taataggctg cttagttgtg aacctgtttg
     2221 atttgcctta agcctctatc cagaaacctg cccgcttccg tctggttaag aagccagtgg
     2281 tggatatttt ctttgttaac attagaaatg caaacattcc cttgtcaacc aagaatactc
     2341 aaagctactt gtattggaaa tggcagaagg cctaaatcca aatttcttat tttttataat
     2401 ttaccataga agttttgtga ttaaattctt acttctgcca gtggaggttt atgcctgaaa
     2461 ggtcatgggg tcctgtctgt aaatagacct aaagagaagt gcagtattta ttctttgtag
     2521 gcataatgtg tttgtcactg acaagcattc atgttcatcc cactagtctt ttattgcagt
     2581 cttttattgt cattttcagc cttatgttgg agagctttgc tttctcatca tgttcacatt
     2641 gtcttaagtt ttgtgagctt ctgagaaaga gcttggtaaa ggtttaaagg ggactttgtt
     2701 ccaccaggga gcattttatt tgggcgtctc acccttttct aatgaaagct gttgtaagcc
     2761 acctctgact tggaaattct gaaagtatga atatttttta tatcttaatt gtaaaatgcc
     2821 agttctccat tatttagatg aatagtagaa cactgcaccc tttgtgcagt gtttttgttt
     2881 ctctactgca ttcctacccc caccaaaaaa aagaaactta aggaaatttt tttttgagac
     2941 agggtctccc tctttcaccc aggctggagt gcagcagcat gatctcagct cactgcagcc
     3001 tctgcctccc aggctcaagc aatcattcca cctcagcctc ttgattagct gggactacag
     3061 gcatgtgcca ccatactcgg ctaattctgt tttaaaaatt ttttttgtag agatgaggtc
     3121 tcactatgtt acccaggctg gtctcgaact tttgggttca agtgatcctc ccgcctcagc
     3181 ctctcaaagt gttagtatta taggtgtgag ccaccatgcc cagcctagaa aatttaacct
     3241 tatcttttag ccattcattt acttttattt gcttttttaa aaaaaaatct ttaaatttta
     3301 gcctagagaa gcacctcagg aactctaaac atcttaggca aaaattaaac tcaggtgaga
     3361 ctgaaggaga aatttcagaa atacacatgt acctcatggg taattaatag acatgcacag
     3421 tttccttcaa atcaaatgtt taataaggaa attcatataa ttccaagaaa acaggcaaaa
     3481 tttggaatac ataagcctag ctaagataaa gaactaccag ttaattctta acatcactgg
     3541 agcttccagc aggtttttta attgaaggac aaaaagtgtc catacatttg tgttatctct
     3601 tcagagcctg agggagaaga gagtggcttt gcccagtgga aaggctgggg atttgagaat
     3661 gatacagggg gaaggagtca agcagaaatg ccaggaagaa ccaggcaaag acatttggcg
     3721 ccagaagcat ccacttaatt tctgtgaaga gtgcccctgg tgtttcatct tggcctgttt
     3781 tgatgagaat gttatctttt gtgtctggat aacgcgtcag cttcttaaag tacatataaa
     3841 gatattctgt cacctcccca catgcacaca cttttaaaat ctatttttat tctcttgcta
     3901 aagttgtaat tatgtcaaga attttccagc tctaactgcc ttcttagtac atgtctttct
     3961 gcctttgaag catatgagtt tgccaaagtc attctcccct aatgacatat tgtggactta
     4021 cattaagaaa atgggccagg cgcggtggct cacacctgta atcccagcac tttaggaggc
     4081 ccaggcgggt ggattacctg aggtcaggag ttcaagacca gactggtcaa catggtgaaa
     4141 ctccatctct actaaaaata cagaaattag ccaggagtgc tgggtggacg cctgcaatcc
     4201 cagctacttg ggaggttgag gcaggagaat tgcttgaacc caggaggcag aggttgcagt
     4261 gagctgagat cataccattg cactccagcc tgcaagacag agtgaaactc ttgtctcaaa
     4321 aaaaaaaaaa gaaaaaaaga aagtgagcct gttgatgtct agctaaccca ttggtggagt
     4381 ctgcattgaa tctgtaagaa tattgttctg gatcatgcag gtgggatttg tataaaaagc
     4441 ctgtccaaca tttagttctc actcgcatca gaatcatact gttttgaatt gccatataag
     4501 acatgctcca tcatgacact tgcttctcct ccaaatacaa gttgagtgct tagtccttca
     4561 cctgctagaa tcaggataca atcaacatga ttatgttcct taacacactt ggatttatgc
     4621 agatgtggtg tgtcctttgc tctttttttt cttaagacag agtcttgctc ttgtcgctca
     4681 ggctggagtg cagtggtgtg atttcggctc actgcaacct ccgcctcctg ggttcaagcg
     4741 attctcctgc ctcagcctcc cgagtagctg ggattacagg caccaccacc ataccaggct
     4801 gatttttttt gtatttttaa tatagacagg gcttcatcat gttggccagg ctggcaggct
     4861 ggtctcgaac tcctcacctc gtgatccgcc cacctcagct tcccaaagtg ctgtgattac
     4921 aggcgtgagc caccgcgcct ggcctgctct taaaacccgt tattcagaag atttgtaaaa
     4981 gaaataggct tttttttttt ttttggttaa ttcaaacgag gggaaaatta gatagcattt
     5041 tcccctaaag aaatgttaat gttcattttg tggctttgtt ttcaagtttc aggagccatg
     5101 tacatctcag aagtgttacg aagtgattag aaaaggcctc tggtaaaaga ccttcaagga
     5161 ccaaccatta ttattggtca cttgtttgaa cttggcgctt aaaaaaaaag ttggactgtg
     5221 atgctttggt gctctttatc acagacatca gtgatggtct gaaacactct ctagcagttt
     5281 atacgaagaa tggacttaca tgttatcagt tacactcatg atttactcgt tcagcttcta
     5341 caagtccata ctttatgctg tctcatttaa gagacagtcc acttctgaaa ataaaatcga
     5401 tagttgatga tacatttttg gctagccagc tttctgtaaa aggcaagtat gttagacatg
     5461 cacagtttcc ttcaaatcaa atgtttaata aggtacttca agaaacgcct ttttaaaaat
     5521 caaaggtttt ggccaggcat ggtggctcac gcctgtaatc ccagcacttt gggaggccaa
     5581 ggtgggcgaa tcacaaggtc aggagtttga gaccagcctg gccaacatgg tgaaaccccg
     5641 tctctactaa aaataccaaa aattagccgg gcgtggtggt gggtacctgt aatcccagct
     5701 actcaggagg ctgagatgag aatcacttga tcccaggagg tagaggttgc agtgagccga
     5761 gattgcgcca ttgcacttca gcctgggcaa cgagtgaaac tctcaaaaaa aaattcatag
     5821 taataataaa gtccctgcat gcagtttgga aataaaattt aaactcattt atgtgtaata
     5881 aatatgtaat aattcacagt caccatcaaa tgttggaatc attgaattgc atacttgtac
     5941 tcattccggc cacatcatga agtgtttaaa gatttgtatt tgctgttgtc cctatgtagt
     6001 tctattgatg tttggttttg ttttttgggg tttgttttga gcccaggcta gagtgcaatg
     6061 gcacaatctc aactcactac agcctggacc tccttggctc aagcagtcct cccacttcag
     6121 cctcccaagt agctggtctg caagtgctca ccaccacacc tggctaattt ttgtattttt
     6181 tgtagagaca gagctctcac tatgttgcct agactggtct caaactcctg ggcccaagca
     6241 atcctcccat cacagcctcc gaaggtgctg ggattacagg cataagccac tgtgcccagc
     6301 ctgtttttaa taatgatatt aagtgggttt ggttcatgtg ttattaatca gtgttaataa
     6361 tcgtactttt tttttttttt aaaagaaacc atggtattct aaaatcagga gtccaaataa
     6421 aagaaagttc tcggctgtgc atggtggcta acacctgtaa tcccagcact ttgggaggct
     6481 gaggtgggtg gatcactaga ggtcaggagt ttgaaacaag cctggccaac atggtaaaac
     6541 cccctctcta ctaaaaatac aaaaattagc cgggcatggt ggtgcacacc tgtaatccca
     6601 gctactcggg atgttgaggc atgagatttc cttgaacctg gaaggcagag gttgctgtga
     6661 gccgagatcg cgccactgca ctccagcctg ggtgacagag taagactgtc gccaaaaaag
     6721 aggaaaaaag ttatccagtg cagtttctac agagataaaa gaagtaatag ttctggctgg
     6781 gtgtggtggc ttatgcctgt aatcccaaca ctttgggagg ccaaggcagg tggatcacat
     6841 gaggtcagga gttcgagacc agcctggcca acatggcaaa actgtctcta ctaaaaatat
     6901 aaaaattagg tatggtggca cgtgcctgta cttacagcta cttgggaggc tgaggcatga
     6961 gatgacaatc tcttgaaccc aggaggcgga ggttgcagtg agctgagatt gcaccactgc
     7021 actccagctt gggtgatgga gtgagactca aataaaaaag gtactagttc tgcatttcag
     7081 agttggcttg ttgaaccagg ctatatgctt ccaagattta aatgtttttc tgtattatac
     7141 tctcaattgt gttttaaaaa aatctcttac agaaatctct acctcaggca ctaagtgtta
     7201 tgacatgggt agcatattga tattgaaaac ttagctagga cttccagcct tttaagataa
     7261 tttaaatgta aaattaaatg gttaaccagc aatctaatgt catgtggtgt gcagtttgga
     7321 tattgcatga acagctaagg aatcacctgt tctagtgcca aagatcactc attgctaatt
     7381 ttgttctgta cagcttatgt aatattttca tggtggagac ggactctgtg tgctcagggc
     7441 cttgtctcta ggaagatttt gtcaattcca aatacagttt tgaagattca
//
