LOCUS       NM_017655               3778 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens GIPC PDZ domain containing family member 2 (GIPC2),
            transcript variant 1, mRNA.
ACCESSION   NM_017655
VERSION     NM_017655.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3778)
  AUTHORS   Wang,L., Wang,J., Yin,X., Guan,X., Li,Y., Xin,C. and Liu,J.
  TITLE     GIPC2 interacts with Fzd7 to promote prostate cancer metastasis by
            activating WNT signaling
  JOURNAL   Oncogene 41 (18), 2609-2623 (2022)
   PUBMED   35347223
  REMARK    GeneRIF: GIPC2 interacts with Fzd7 to promote prostate cancer
            metastasis by activating WNT signaling.
REFERENCE   2  (bases 1 to 3778)
  AUTHORS   Dong,Y., Huang,Y., Fan,C., Wang,L., Zhang,R., Li,W., Guo,Z.,
            Wang,D. and Zheng,Z.
  TITLE     GIPC2 is an endocrine-specific tumor suppressor gene for both
            sporadic and hereditary tumors of RET- and SDHB-, but not
            VHL-associated clusters of pheochromocytoma/paraganglioma
  JOURNAL   Cell Death Dis 12 (5), 444 (2021)
   PUBMED   33947839
  REMARK    GeneRIF: GIPC2 is an endocrine-specific tumor suppressor gene for
            both sporadic and hereditary tumors of RET- and SDHB-, but not
            VHL-associated clusters of pheochromocytoma/paraganglioma.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3778)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 3778)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3778)
  AUTHORS   Lango Allen,H., Estrada,K., Lettre,G., Berndt,S.I., Weedon,M.N.,
            Rivadeneira,F., Willer,C.J., Jackson,A.U., Vedantam,S.,
            Raychaudhuri,S., Ferreira,T., Wood,A.R., Weyant,R.J., Segre,A.V.,
            Speliotes,E.K., Wheeler,E., Soranzo,N., Park,J.H., Yang,J.,
            Gudbjartsson,D., Heard-Costa,N.L., Randall,J.C., Qi,L., Vernon
            Smith,A., Magi,R., Pastinen,T., Liang,L., Heid,I.M., Luan,J.,
            Thorleifsson,G., Winkler,T.W., Goddard,M.E., Sin Lo,K., Palmer,C.,
            Workalemahu,T., Aulchenko,Y.S., Johansson,A., Zillikens,M.C.,
            Feitosa,M.F., Esko,T., Johnson,T., Ketkar,S., Kraft,P., Mangino,M.,
            Prokopenko,I., Absher,D., Albrecht,E., Ernst,F., Glazer,N.L.,
            Hayward,C., Hottenga,J.J., Jacobs,K.B., Knowles,J.W., Kutalik,Z.,
            Monda,K.L., Polasek,O., Preuss,M., Rayner,N.W., Robertson,N.R.,
            Steinthorsdottir,V., Tyrer,J.P., Voight,B.F., Wiklund,F., Xu,J.,
            Zhao,J.H., Nyholt,D.R., Pellikka,N., Perola,M., Perry,J.R.,
            Surakka,I., Tammesoo,M.L., Altmaier,E.L., Amin,N., Aspelund,T.,
            Bhangale,T., Boucher,G., Chasman,D.I., Chen,C., Coin,L.,
            Cooper,M.N., Dixon,A.L., Gibson,Q., Grundberg,E., Hao,K., Juhani
            Junttila,M., Kaplan,L.M., Kettunen,J., Konig,I.R., Kwan,T.,
            Lawrence,R.W., Levinson,D.F., Lorentzon,M., McKnight,B.,
            Morris,A.P., Muller,M., Suh Ngwa,J., Purcell,S., Rafelt,S.,
            Salem,R.M., Salvi,E., Sanna,S., Shi,J., Sovio,U., Thompson,J.R.,
            Turchin,M.C., Vandenput,L., Verlaan,D.J., Vitart,V., White,C.C.,
            Ziegler,A., Almgren,P., Balmforth,A.J., Campbell,H., Citterio,L.,
            De Grandi,A., Dominiczak,A., Duan,J., Elliott,P., Elosua,R.,
            Eriksson,J.G., Freimer,N.B., Geus,E.J., Glorioso,N., Haiqing,S.,
            Hartikainen,A.L., Havulinna,A.S., Hicks,A.A., Hui,J., Igl,W.,
            Illig,T., Jula,A., Kajantie,E., Kilpelainen,T.O., Koiranen,M.,
            Kolcic,I., Koskinen,S., Kovacs,P., Laitinen,J., Liu,J., Lokki,M.L.,
            Marusic,A., Maschio,A., Meitinger,T., Mulas,A., Pare,G.,
            Parker,A.N., Peden,J.F., Petersmann,A., Pichler,I.,
            Pietilainen,K.H., Pouta,A., Ridderstrale,M., Rotter,J.I.,
            Sambrook,J.G., Sanders,A.R., Schmidt,C.O., Sinisalo,J., Smit,J.H.,
            Stringham,H.M., Bragi Walters,G., Widen,E., Wild,S.H.,
            Willemsen,G., Zagato,L., Zgaga,L., Zitting,P., Alavere,H.,
            Farrall,M., McArdle,W.L., Nelis,M., Peters,M.J., Ripatti,S., van
            Meurs,J.B., Aben,K.K., Ardlie,K.G., Beckmann,J.S., Beilby,J.P.,
            Bergman,R.N., Bergmann,S., Collins,F.S., Cusi,D., den Heijer,M.,
            Eiriksdottir,G., Gejman,P.V., Hall,A.S., Hamsten,A., Huikuri,H.V.,
            Iribarren,C., Kahonen,M., Kaprio,J., Kathiresan,S., Kiemeney,L.,
            Kocher,T., Launer,L.J., Lehtimaki,T., Melander,O., Mosley,T.H. Jr.,
            Musk,A.W., Nieminen,M.S., O'Donnell,C.J., Ohlsson,C., Oostra,B.,
            Palmer,L.J., Raitakari,O., Ridker,P.M., Rioux,J.D., Rissanen,A.,
            Rivolta,C., Schunkert,H., Shuldiner,A.R., Siscovick,D.S.,
            Stumvoll,M., Tonjes,A., Tuomilehto,J., van Ommen,G.J., Viikari,J.,
            Heath,A.C., Martin,N.G., Montgomery,G.W., Province,M.A., Kayser,M.,
            Arnold,A.M., Atwood,L.D., Boerwinkle,E., Chanock,S.J., Deloukas,P.,
            Gieger,C., Gronberg,H., Hall,P., Hattersley,A.T., Hengstenberg,C.,
            Hoffman,W., Lathrop,G.M., Salomaa,V., Schreiber,S., Uda,M.,
            Waterworth,D., Wright,A.F., Assimes,T.L., Barroso,I., Hofman,A.,
            Mohlke,K.L., Boomsma,D.I., Caulfield,M.J., Cupples,L.A.,
            Erdmann,J., Fox,C.S., Gudnason,V., Gyllensten,U., Harris,T.B.,
            Hayes,R.B., Jarvelin,M.R., Mooser,V., Munroe,P.B., Ouwehand,W.H.,
            Penninx,B.W., Pramstaller,P.P., Quertermous,T., Rudan,I.,
            Samani,N.J., Spector,T.D., Volzke,H., Watkins,H., Wilson,J.F.,
            Groop,L.C., Haritunians,T., Hu,F.B., Kaplan,R.C., Metspalu,A.,
            North,K.E., Schlessinger,D., Wareham,N.J., Hunter,D.J.,
            O'Connell,J.R., Strachan,D.P., Wichmann,H.E., Borecki,I.B., van
            Duijn,C.M., Schadt,E.E., Thorsteinsdottir,U., Peltonen,L.,
            Uitterlinden,A.G., Visscher,P.M., Chatterjee,N., Loos,R.J.,
            Boehnke,M., McCarthy,M.I., Ingelsson,E., Lindgren,C.M.,
            Abecasis,G.R., Stefansson,K., Frayling,T.M. and Hirschhorn,J.N.
  TITLE     Hundreds of variants clustered in genomic loci and biological
            pathways affect human height
  JOURNAL   Nature 467 (7317), 832-838 (2010)
   PUBMED   20881960
REFERENCE   6  (bases 1 to 3778)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   7  (bases 1 to 3778)
  AUTHORS   Vieira,A.R., McHenry,T.G., Daack-Hirsch,S., Murray,J.C. and
            Marazita,M.L.
  TITLE     Candidate gene/loci studies in cleft lip/palate and dental
            anomalies finds novel susceptibility genes for clefts
  JOURNAL   Genet Med 10 (9), 668-674 (2008)
   PUBMED   18978678
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   8  (bases 1 to 3778)
  AUTHORS   Stelzl,U., Worm,U., Lalowski,M., Haenig,C., Brembeck,F.H.,
            Goehler,H., Stroedicke,M., Zenkner,M., Schoenherr,A., Koeppen,S.,
            Timm,J., Mintzlaff,S., Abraham,C., Bock,N., Kietzmann,S.,
            Goedde,A., Toksoz,E., Droege,A., Krobitsch,S., Korn,B.,
            Birchmeier,W., Lehrach,H. and Wanker,E.E.
  TITLE     A human protein-protein interaction network: a resource for
            annotating the proteome
  JOURNAL   Cell 122 (6), 957-968 (2005)
   PUBMED   16169070
REFERENCE   9  (bases 1 to 3778)
  AUTHORS   Katoh,M.
  TITLE     GIPC gene family (Review)
  JOURNAL   Int J Mol Med 9 (6), 585-589 (2002)
   PUBMED   12011974
  REMARK    Review article
REFERENCE   10 (bases 1 to 3778)
  AUTHORS   Kirikoshi,H. and Katoh,M.
  TITLE     Molecular cloning and characterization of human GIPC2, a novel gene
            homologous to human GIPC1 and Xenopus Kermit
  JOURNAL   Int J Oncol 20 (3), 571-576 (2002)
   PUBMED   11836570
  REMARK    GeneRIF: Molecular cloning and characterization of human GIPC2, a
            novel gene homologous to human GIPC1 and Xenopus Kermit
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC103591.3 and AC093118.2.
            
            On Nov 23, 2018 this sequence version replaced NM_017655.5.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.16227.1, BC036075.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000370759.4/ ENSP00000359795.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-369               AC103591.3         45943-46311         c
            370-555             AC103591.3         11417-11602         c
            556-736             AC093118.2         86335-86515
            737-843             AC093118.2         110776-110882
            844-925             AC093118.2         117264-117345
            926-3778            AC093118.2         126975-129827
FEATURES             Location/Qualifiers
     source          1..3778
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p31.1"
     gene            1..3778
                     /gene="GIPC2"
                     /gene_synonym="SEMCAP-2; SEMCAP2"
                     /note="GIPC PDZ domain containing family member 2"
                     /db_xref="GeneID:54810"
                     /db_xref="HGNC:HGNC:18177"
                     /db_xref="MIM:619089"
     exon            1..369
                     /gene="GIPC2"
                     /gene_synonym="SEMCAP-2; SEMCAP2"
                     /inference="alignment:Splign:2.1.0"
     CDS             130..1077
                     /gene="GIPC2"
                     /gene_synonym="SEMCAP-2; SEMCAP2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     semaphorin cytoplasmic domain associated protein 2; PDZ
                     domain-containing protein GIPC2; PDZ domain protein GIPC2;
                     semaF cytoplasmic domain associated protein 2; epididymis
                     secretory sperm binding protein"
                     /codon_start=1
                     /product="PDZ domain-containing protein GIPC2 isoform 1"
                     /protein_id="NP_060125.4"
                     /db_xref="CCDS:CCDS685.1"
                     /db_xref="GeneID:54810"
                     /db_xref="HGNC:HGNC:18177"
                     /db_xref="MIM:619089"
                     /translation="MPLKLRGKKKAKSKETAGLVEGEPTGAGGGSLSASRAPARRLVF
                     HAQLAHGSATGRVEGFSSIQELYAQIAGAFEISPSEILYCTLNTPKIDMERLLGGQLG
                     LEDFIFAHVKGIEKEVNVYKSEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGD
                     HIESINGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKKAFEIELRSKAGKSSGEKI
                     GCGRATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMGIRDIDLATTMFEAGKDK
                     VNPDEFAVALDETLGDFAFPDEFVFDVWGVIGDAKRRGL"
     exon            370..555
                     /gene="GIPC2"
                     /gene_synonym="SEMCAP-2; SEMCAP2"
                     /inference="alignment:Splign:2.1.0"
     exon            556..736
                     /gene="GIPC2"
                     /gene_synonym="SEMCAP-2; SEMCAP2"
                     /inference="alignment:Splign:2.1.0"
     exon            737..843
                     /gene="GIPC2"
                     /gene_synonym="SEMCAP-2; SEMCAP2"
                     /inference="alignment:Splign:2.1.0"
     exon            844..925
                     /gene="GIPC2"
                     /gene_synonym="SEMCAP-2; SEMCAP2"
                     /inference="alignment:Splign:2.1.0"
     exon            926..3778
                     /gene="GIPC2"
                     /gene_synonym="SEMCAP-2; SEMCAP2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2555..2560
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GIPC2"
                     /gene_synonym="SEMCAP-2; SEMCAP2"
                     /note="hexamer: AATAAA"
     polyA_site      2578
                     /gene="GIPC2"
                     /gene_synonym="SEMCAP-2; SEMCAP2"
                     /note="major polyA site"
     regulatory      3757..3762
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GIPC2"
                     /gene_synonym="SEMCAP-2; SEMCAP2"
                     /note="hexamer: AATACA"
     polyA_site      3778
                     /gene="GIPC2"
                     /gene_synonym="SEMCAP-2; SEMCAP2"
                     /note="major polyA site"
ORIGIN      
        1 aggcggaagc gcggctgcca ttggaggctg cttttacctg cgcggggccc ggggcgcaaa
       61 gtccgaggcg ccggggggag gaggcggcgg acggcagcgc aggtgggccc gcgctctcgg
      121 ccctgcaaga tgcccctgaa gctgcggggg aagaagaagg ccaagtccaa ggagaccgcc
      181 gggctggtgg agggcgagcc gacgggcgcg ggcggcggga gcctctcagc gtcccgggct
      241 cccgcacgca ggctggtctt ccacgcgcag ctggcgcacg gtagtgccac gggccgagtg
      301 gagggcttct ccagcatcca ggagctctac gcccagatcg cgggcgcgtt tgaaatctcg
      361 ccgtcggaga tcttatattg cactttaaac acacctaaaa ttgacatgga aagactctta
      421 ggaggacaac taggactaga agatttcata tttgcccatg tgaaaggaat cgaaaaagaa
      481 gtgaatgtgt ataaatctga ggattcactt ggtctcacca ttacagataa tggtgttggc
      541 tatgctttta taaagagaat taaagatggt ggtgttattg actcagttaa aacaatctgt
      601 gttggggatc atattgaatc cataaatgga gaaaatattg ttgggtggcg tcactatgat
      661 gttgctaaga agttaaagga attaaaaaag gaggaactct ttactatgaa gttaatagaa
      721 cctaagaagg catttgaaat agagctgagg tcaaaggctg gaaagtcatc aggagaaaaa
      781 attggttgtg gaagggcaac acttcgcctg agatcaaaag gtcctgccac cgtggaagaa
      841 atgccttctg aaaccaaagc aaaggcaatt gaaaagattg atgatgttct tgagttgtac
      901 atgggaattc gagatattga tttagccacc acaatgtttg aagctggaaa ggacaaagta
      961 aatccagatg aatttgctgt ggcacttgac gaaactcttg gagactttgc gttcccagac
     1021 gaatttgtct ttgatgtttg gggagtcatt ggtgatgcca aacgaagagg attatgatgt
     1081 gtacactcca tctctgaaga aacaacccat cgttcttttt tttctctttt ttaaaaagtc
     1141 ctataagatc tgtttttgga cacctttact aactctggtt taatttcatg tgtatggaat
     1201 atattctttg aaatataatt ttggtaattt tgatttctgg gcacttttta acattgctga
     1261 tgtagtatgc ttaagagaaa tgacctaaat aaggatcaat tgtaatattc attcaaaagg
     1321 tttttaaaag taagttttaa ggagtatttc tcgacagatg attttcttct ccattaatac
     1381 ccatgctttg tttttcacat ataaatagat gatttcaata gctttgtagt tttttttcaa
     1441 aatcttaatg taaactagga ttggagtatg atttacctca tagtatcttc actgtgttat
     1501 cctagtttga acaggatatg ttcaggaaat gaaaggtgaa ttatgcccct tattggtcta
     1561 gaagcattgg tttttttttg atcctctgag taagggaagg aagattcctg tggcatgttg
     1621 atttctatgg ccaactttct ctctttgtaa aacaaagatt gattgatttt cttgtatgct
     1681 tctttataca tgctcttaaa acttgtggtt gaaatctgtg ctgtgtgtgt gtgtctctgc
     1741 atgtgtaaaa gaagggtaaa aaagagatgg gtagggtaga actacttgca tttgattttt
     1801 ttttcagtcc ttaaaacatt atttcttttt ttcactcata gccactttta tgttaccttt
     1861 tataagcact ccagggaaga ttttatattt ttttgtagag tttttggaaa gatatttact
     1921 caaaataact atgctttaga actttttttt tttttttttt tttggttaaa cagcagcact
     1981 ttttagttcc ctaaacttta gaagaaatgc tatcagaaat agatttcctt ccagtggaaa
     2041 gaaaggagga agggagaatt gagaaaatat attagtctat tattttagag ttctaataca
     2101 ctctaaatta aagagaaaat tgagagtaaa tgactgtctt atcactctta tttgacattt
     2161 cgtaggtgta agagaaatgg aaatgaatgg tttcaacaaa gatcatttaa tacagcagag
     2221 catggcatga ccaagcatct ttgtaaagtg ttagatggaa aatgctgtgt gctgccatgg
     2281 taatcagaaa taataacctg ttagggatgt attctaggaa atcagaagta gttctctttt
     2341 cttgctggat tattgcttag ataactcttg ttttctggta aaactttagt tgtattgcca
     2401 tccactcctt tttcaaatga gtttaatgcc ataaagctga tattctttgt ccgattaatt
     2461 tgaaatctgc acagaagctg ttttagtcat taatgtgtaa caaaagtagc ttatagaata
     2521 tggactgcct tattgctgtt gcttatcatt tgaaaataaa atccagctca ggttgtaact
     2581 tgttggtact cgtttagtga gttcgttttg gaggttctga aatacctatt aattcttaat
     2641 attacctctc ttggaaagac acaaaaaaag agctgttatt tttaggcata agatgactta
     2701 ggaggcccat agaaacattc tcgtttaaac aacaacaaca aaataaattt atcagcacta
     2761 gatattagat ttgaaataag tcattgttca ttattgatgg ttgtcagttt ctccttcctt
     2821 tttgggcatg cataaagaca cacttggtgc tgattccatg tgatttatgg aatgtcattt
     2881 tcacaatgat ctttctagaa tttgtgtgta aggttgtgat atccatgtac agctgtaact
     2941 atatatactt gtctgttagc attcagtgga ccattatcat tactatcatc acattacctg
     3001 ggcttcaact gggcccaagt actctatata ctgcctgtaa taggtttttc cttgaaatat
     3061 ccttatcttt cacctctaca gctaaactga taacaaggtc agtttcttta tgtcatttta
     3121 ttcccatacc taaaattgca tctatttgtg agctttctgc ctttttgtaa cgctcagtgc
     3181 accaaaagcg tctgttttta gtgcagtcac ataatatata agtgtgggat acccttctgc
     3241 agcttcagtg agacaaatca ctttttaaaa aacattccat tttattggca tcactagatg
     3301 tttttaggac cctgtccttt tcacttttct gtaggctttt tttttttaaa tggaagatga
     3361 ttattttgtt tgttcttgat ttcctgttat tgaaaacagc atcttccttc ttgcaatggc
     3421 cactaatagc acacaatgcg ttttctttga ttgtagcaga aaatgcaaat gataattgta
     3481 tgttgggctc gatgaggcct tgaacatagc tgagtcctaa tcagatgtat atactctgat
     3541 gattacaaat aggtacatgt tgggtttctg tgatgtttca aaaatacaat tatataatta
     3601 tgatgtaaac tctttaagaa ttcaattata aaagcaataa tcaggtaacc tctatttgga
     3661 gctgctacat ccaatattgt gactgaaaat taactaaaga gagataattt ttcaaatgat
     3721 gtataatttg caatattttc ccttgcaact ttagcaaata cacatattcc aagtaaaa
//
