LOCUS       NM_138785               1943 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens glycosylated integral membrane protein 1 (GINM1),
            mRNA.
ACCESSION   NM_138785
VERSION     NM_138785.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1943)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1943)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
REFERENCE   3  (bases 1 to 1943)
  AUTHORS   Clark,H.F., Gurney,A.L., Abaya,E., Baker,K., Baldwin,D., Brush,J.,
            Chen,J., Chow,B., Chui,C., Crowley,C., Currell,B., Deuel,B.,
            Dowd,P., Eaton,D., Foster,J., Grimaldi,C., Gu,Q., Hass,P.E.,
            Heldens,S., Huang,A., Kim,H.S., Klimowski,L., Jin,Y., Johnson,S.,
            Lee,J., Lewis,L., Liao,D., Mark,M., Robbie,E., Sanchez,C.,
            Schoenfeld,J., Seshagiri,S., Simmons,L., Singh,J., Smith,V.,
            Stinson,J., Vagts,A., Vandlen,R., Watanabe,C., Wieand,D., Woods,K.,
            Xie,M.H., Yansura,D., Yi,S., Yu,G., Yuan,J., Zhang,M., Zhang,Z.,
            Goddard,A., Wood,W.I., Godowski,P. and Gray,A.
  TITLE     The secreted protein discovery initiative (SPDI), a large-scale
            effort to identify novel human secreted and transmembrane proteins:
            a bioinformatics assessment
  JOURNAL   Genome Res 13 (10), 2265-2270 (2003)
   PUBMED   12975309
  REMARK    Erratum:[Genome Res. 2003 Dec;13(12):2759]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            HY049714.1, BC014320.1, BU621398.1, AA903253.1, AL078581.11 and
            AI245018.1.
            
            On Nov 23, 2018 this sequence version replaced NM_138785.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR3476690.44926.1,
                                           SRR3476690.195570.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000367419.10/ ENSP00000356389.5
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                HY049714.1         168-184
            18-1126             BC014320.1         5-1113
            1127-1711           BU621398.1         15-599              c
            1712-1743           AA903253.1         14-45               c
            1744-1933           AL078581.11        68160-68349
            1934-1943           AI245018.1         34-43               c
FEATURES             Location/Qualifiers
     source          1..1943
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q25.1"
     gene            1..1943
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
                     /note="glycosylated integral membrane protein 1"
                     /db_xref="GeneID:116254"
                     /db_xref="HGNC:HGNC:21074"
     exon            1..160
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..1033
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
                     /note="glycoprotein integral membrane protein 1;
                     glycoprotein integral membrane 1"
                     /codon_start=1
                     /product="glycoprotein integral membrane protein 1
                     precursor"
                     /protein_id="NP_620140.1"
                     /db_xref="CCDS:CCDS5216.1"
                     /db_xref="GeneID:116254"
                     /db_xref="HGNC:HGNC:21074"
                     /translation="MEGAPPGSLALRLLLFVALPASGWLTTGAPEPPPLSGAPQDGIR
                     INVTTLKDDGDISKQQVVLNITYESGQVYVNDLPVNSGVTRISCQTLIVKNENLENLE
                     EKEYFGIVSVRILVHEWPMTSGSSLQLIVIQEEVVEIDGKQVQQKDVTEIDILVKNRG
                     VLRHSNYTLPLEESMLYSISRDSDILFTLPNLSKKESVSSLQTTSQYLIRNVETTVDE
                     DVLPGKLPETPLRAEPPSSYKVMCQWMEKFRKDLCRFWSNVFPVFFQFLNIMVVGITG
                     AAVVITILKVFFPVSEYKGILQLDKVDVIPVTAINLYPDGPEKRAENLEDKTCI"
     exon            161..220
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
                     /inference="alignment:Splign:2.1.0"
     exon            221..317
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
                     /inference="alignment:Splign:2.1.0"
     exon            318..469
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
                     /inference="alignment:Splign:2.1.0"
     exon            470..626
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
                     /inference="alignment:Splign:2.1.0"
     exon            627..757
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
                     /inference="alignment:Splign:2.1.0"
     exon            758..921
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
                     /inference="alignment:Splign:2.1.0"
     exon            922..1943
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1092..1097
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
                     /note="hexamer: AATATA"
     polyA_site      1116
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
                     /note="major polyA site"
     regulatory      1718..1723
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
                     /note="hexamer: TATAAA"
     polyA_site      1743
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
     regulatory      1805..1810
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
                     /note="hexamer: TATAAA"
     polyA_site      1824
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
     regulatory      1910..1915
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
                     /note="hexamer: AATAAA"
     polyA_site      1911
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
     polyA_site      1943
                     /gene="GINM1"
                     /gene_synonym="C6orf72"
ORIGIN      
        1 acctcccggc cgcggctgcc ctctgcccgg gttgtccaag atggagggcg ctccaccggg
       61 gtcgctcgcc ctccggctcc tgctgttcgt ggcgctaccc gcctccggct ggctgacgac
      121 gggcgccccc gagccgccgc cgctgtccgg agccccacag gacggcatca gaattaatgt
      181 aactacactg aaagatgatg gggacatatc taaacagcag gttgttctta acataaccta
      241 tgagagtgga caggtgtatg taaatgactt acctgtaaat agtggtgtaa cccgaataag
      301 ctgtcagact ttgatagtga agaatgaaaa tcttgaaaat ttggaggaaa aagaatattt
      361 tggaattgtc agtgtaagga ttttagttca tgagtggcct atgacatctg gttccagttt
      421 gcaactaatt gtcattcaag aagaggtagt agagattgat ggaaaacaag ttcagcaaaa
      481 ggatgtcact gaaattgata ttttagttaa gaaccgggga gtactcagac attcaaacta
      541 taccctccct ttggaagaaa gcatgctcta ctctatttct cgagacagtg acattttatt
      601 tacccttcct aacctctcca aaaaagaaag tgttagttca ctgcaaacca ctagccagta
      661 tcttatcagg aatgtggaaa ccactgtaga tgaagatgtt ttacctggca agttacctga
      721 aactcctctc agagcagagc cgccatcttc atataaggta atgtgtcagt ggatggaaaa
      781 gtttagaaaa gatctgtgta ggttctggag caacgttttc ccagtattct ttcagttttt
      841 gaacatcatg gtggttggaa ttacaggagc agctgtggta ataaccatct taaaggtgtt
      901 tttcccagtt tctgaataca aaggaattct tcagttggat aaagtggacg tcatacctgt
      961 gacagctatc aacttatatc cagatggtcc agagaaaaga gctgaaaacc ttgaagataa
     1021 aacatgtatt taaaacgcca tctcatatca tggactccga agtagcctgt tgcctccaaa
     1081 tttgccactt gaatataatt ttctttaaat cgttaagaat cagtttatac actagagaaa
     1141 ttgctaaact ctaagactgc ctgaaaattg acctttacag tgccaagtta aagtttacct
     1201 tattctcggc cgggtgcagt ggctcatgcc tgtaatccca ggactttggg aggccaatgc
     1261 gggcggatca cgaggtcaga tcaagaccat cctgccaaca tggtgaaacc ctgtctctac
     1321 taaaaaaaat aaaaaaatta gctgggtgtg gcggtgcacg cctgtagtcc cagctacttg
     1381 ggaggctgag gcaggagaat tgcttgaacc cgggaggcgg aggctgcagt gagccaagat
     1441 cacgccactg cactccagcc tgggtgacag agcgagactc tgtttcaaaa aaaaaaaagt
     1501 tgaccttatt ctctaaaagg gctggctatt catatgatga attgttaagg aaaacttaaa
     1561 gtggaagaga acacatgtga agagactttg aaattatcaa aagaaaaaaa aaagaccaga
     1621 caaaatctca tgtgccaata acttttcaag gtgcctttgt taaggaaatt atatccactt
     1681 aattactata atatataaga ctttatgaaa agcactttat aaaattctaa tttaaaaggt
     1741 caagaactta acacttattt ttttattcag tacagtgtgc ctttatatta agtatgtgac
     1801 tcagtataaa atcactgaag tgtatcatga tttgattgta tcctgtacca agactactta
     1861 ccttgaatgc tccaagattt aaaagtagta tgacatgttc tcactctaaa ataaactttt
     1921 tttttttttt tttgaggaaa aaa
//
