LOCUS       XM_047443919            6709 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens gamma-glutamyl carboxylase (GGCX),
            transcript variant X3, mRNA.
ACCESSION   XM_047443919
VERSION     XM_047443919.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6709
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..6709
                     /gene="GGCX"
                     /gene_synonym="VKCFD1"
                     /note="gamma-glutamyl carboxylase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 22 ESTs, 1936 long SRA reads, and 91% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 58 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:2677"
                     /db_xref="HGNC:HGNC:4247"
                     /db_xref="MIM:137167"
     CDS             41..1495
                     /gene="GGCX"
                     /gene_synonym="VKCFD1"
                     /codon_start=1
                     /product="vitamin K-dependent gamma-carboxylase isoform
                     X3"
                     /protein_id="XP_047299875.1"
                     /db_xref="GeneID:2677"
                     /db_xref="HGNC:HGNC:4247"
                     /db_xref="MIM:137167"
                     /translation="MQTGLKAIPWNICPGTGSSVPSSMFSYVMLASSPLFCSPEWPRK
                     LVSYCPRRLQQLLPLKAAPQPSVSCVYKRSRGKSGQKPGLRHQLGAAFTLLYLLEQLF
                     LPYSHFLTQGYNNWTNGLYGYSWDMMVHSRSHQHVKITYRDGRTGELGYLNPGVFTQS
                     RRWKDHADMLKQYATCLSRLLPKYNVTEPQIYFDIWVSINDRFQQRIFDPRVDIVQAA
                     WSPFQRTSWVQPLLMDLSPWRAKLQEIKSSLDNHTEVVFIADFPGLHLENFVSEDLGN
                     TSIQLLQGEVTVELVAEQKNQTLREGEKMQLPAGEYHKVYTTSPSPSCYMYVYVNTTE
                     LALEQDLAYLQELKEKVENGSETGPLPPELQPLLEGEVKGGPEPTPLVQTFLRRQQRL
                     QEIERRRNTPFHERFFRFLLRKLYVFRRSFLMTCISLRNLILGRPSLEQLAQEVTYAN
                     LRPFEAVGELNPSNTDSSHSNPPESNPDPVHSEF"
ORIGIN      
        1 atcttcattg tgtacttcat tgcgggtgtg aaaaagctgg atgcagactg ggttgaaggc
       61 tattccatgg aatatttgtc ccggcactgg ctcttcagtc ccttcaagta tgttctccta
      121 cgtcatgctg gccagcagcc ctctcttctg ctcccctgag tggcctcgga agctggtgtc
      181 ctactgcccc cgaaggttgc aacaactgtt gcccctcaag gcagcccctc agcccagtgt
      241 ttcctgtgtg tataagagga gccggggcaa aagtggccag aagccagggc tgcgccatca
      301 gctgggagct gccttcaccc tgctctacct cctggagcag ctattcctgc cctattctca
      361 ttttctcacc cagggctata acaactggac aaatgggctg tatggctatt cctgggacat
      421 gatggtgcac tcccgctccc accagcacgt gaagatcacc taccgtgatg gccgcactgg
      481 cgaactgggc taccttaacc ctggggtatt tacacagagt cggcgatgga aggatcatgc
      541 agacatgctg aagcaatatg ccacttgcct gagccgcctg cttcccaagt ataatgtcac
      601 tgagccccag atctactttg atatttgggt ctccatcaat gaccgcttcc agcagaggat
      661 ttttgaccct cgtgtggaca tcgtgcaggc cgcttggtca ccctttcagc gcacatcctg
      721 ggtgcaacca ctcttgatgg acctgtctcc ctggagggcc aagttacagg aaatcaagag
      781 cagcctagac aaccacactg aggtggtctt cattgcagat ttccctggac tgcacttgga
      841 gaattttgtg agtgaagacc tgggcaacac tagcatccag ctgctgcagg gggaagtgac
      901 tgtggagctt gtggcagaac agaagaacca gactcttcga gagggagaaa aaatgcagtt
      961 gcctgctggt gagtaccata aggtgtatac gacatcacct agcccttctt gctacatgta
     1021 cgtctatgtc aacactacag agcttgcact ggagcaagac ctggcatatc tgcaagaatt
     1081 aaaggaaaag gtggagaatg gaagtgaaac agggcctcta cccccagagc tgcagcctct
     1141 gttggaaggg gaagtaaaag ggggccctga gccaacacct ctggttcaga cctttcttag
     1201 acgccaacaa aggctccagg agattgaacg ccggcgaaat actcctttcc atgagcgatt
     1261 cttccgcttc ttgttgcgaa agctctatgt ctttcgccgc agcttcctga tgacttgtat
     1321 ctcacttcga aatctgatat taggccgtcc ttccctggag cagctggccc aggaggtgac
     1381 ttatgcaaac ttgagaccct ttgaggcagt tggagaactg aatccctcaa acacggattc
     1441 ttcacattct aatcctcctg agtcaaatcc tgatcctgtc cactcagagt tctgaagggg
     1501 gccagatgtt gggtgcagat gtagaagcag ccagtcacag acccattcta tgcaatggac
     1561 atttatttga aaaaaattct caaaagtttt tttttttttt ttgggggggc ggggttctaa
     1621 agctgttttt aactccgaga ttacaactta gaggaaccaa ggaaataaag caaataagat
     1681 ttaacaaccc aagattaaga ggccaggaag aggttagacg caatgtgaaa ctgtcctcct
     1741 aggataaggt ttaaagtggc tttttggggg ctgggtgccg tggctcacgc ctgtaatccc
     1801 agcattttgg gaggctgagg tgggcagatc acttgaggcc aggagttcga gaccagcctg
     1861 gccaacatgg caaaacccct tctctactaa aaatacaaaa attagccaga cgtggtggtg
     1921 ggtgcctgta atccaactac ccaggaggct gaggcatgag aatcgcttgg gcccaggagg
     1981 tggaggttgc agtgagccga gatcgagcca ctgcactcct gggcaacaga gcaagacttc
     2041 gtctcaaaat aaataaataa agtggctctt ggggaaaagc aatttaatgt accacgatga
     2101 atagctaact gttcccaagt gtttgctatg tgcaacacac cgcgtgagca gtgttacctg
     2161 cattattaca ttaggctgag aggtaaaata atttgcccga agacatacag ctagtgacga
     2221 atggactgat ggtttgaact taacgtctat ttgacttaag gtcctgcacc ctgccacttg
     2281 taattttcag aatcactgat aatctgaaat aatgcagctt aaaacatgtt ttcttaatta
     2341 aaagtataat tggatggtgg tcaggttgta aatgcacaca aagtaattta tcttcattgc
     2401 aattttggtt ccttctttgt tcctattatc tatatacacc cagtgtttca ctagcagtta
     2461 tgagagcagt cagaatagca gcatcaaagt taaataagga aatctagatg attgctagat
     2521 tttctctaaa aataagctta gtatttggta ttattctagc ctttggtgag cagaagggga
     2581 ggtaaagtaa gaattaacta aatttagtaa gggattaggg aatgcttaga cattttgtag
     2641 gttggggtat acaagggtaa ctcaggaagc tcctcagttc agtgaaaatt caaagggttg
     2701 gcactgagct aggaagcgag aatgcagggt tatgaaaaag gatccctgct ttgggagctc
     2761 atggacttgt agcagagacc ggtagtaaat tggcagtctc agtaacttct gtaaatgatt
     2821 gcatctcttt gcaggcttct cttcccatac tctcccccac tcctccttgg acagtgttcc
     2881 gggggttctt tcctaagcaa ctgctttttc agtatacata cttcagatga ttgtgtctac
     2941 tccaggattt ccaacgatgc taggtttctt tcctgtgccc tagacgtata ggtctaagtt
     3001 ccacctggat atcccacagg gctatcaagc tcagttcatc ctaaacagaa cttacattca
     3061 tccccaactc agacttcctt attctttatt attgaatggc agctctgtac cttagccaag
     3121 ctgttatctc taggtcatca gccttgactc ttcctttttc cttgcatttc ttaaaattgc
     3181 caagtcccat caattttacc tcctggatac ctcttgaatc tatttttttt taaagacagg
     3241 gtttcactct atcacccagg ctggagttca gtggcacaat cttggcttac tgcagccacc
     3301 acctcctggg tttaaacgat tcttccactt cagcctccca tgtagctggg actacaggtg
     3361 cccaccacca cgcccaacta atttttgtat ttttagtaga gacatggttt cccacattgg
     3421 ccaggctggt ctcaaactca tgaccttaag tatccacctg ccttggcctc ccaaagggct
     3481 gggattacag gtgtgagcca ccgtgcccag ccaaatctgt tttcattact acctatatct
     3541 gtattttcaa cctttgtatt agcatctagt tagggataga ccaggacagg gccgacatgt
     3601 tagttgtcaa gcagattgcc accctccccc accactgagg aggccaaatg gagtttggtg
     3661 gaaaatctct aattcattca aggtattata tgggcaagca atggctgtgg cacagggtcc
     3721 cctgattact ttgtaagaat gggtgggagg gatgctgatt ttcaatcctt ttgcagatct
     3781 tctctcatag taacacaata gaagatactt tgccactatg ttgtttgcca aactcactgt
     3841 acctacttga ctggtaacaa aagtcccaag agttacttgg gagaagacac ttgaaaaagt
     3901 atttttctaa atatgggcaa ggatgctgcc cttccccaaa ctgttagtat accacctctc
     3961 tgaccaattt tcccaaggaa gatattgggg tagggtgagg tgtaaagaaa aagtggtcat
     4021 gtaaatactg gtaataaaag ctgttcagtg gggtagagtt gggttgcaac tgtagccatt
     4081 ctaaaaatgg gctatcaatg tccttttagc caaaagactt tagtatacat cctcctcatt
     4141 ctaccctcag gatttggatc tttgcccctg atgggtatcc atcccctttg aaactttaga
     4201 aaggcaggtt atatacagaa tgttcaacct aaagacattt ccttaagtca tactttcatg
     4261 ctttctaaac tataatcacc cttatcatcc cctgctgtta tgctttccct ctgctccctg
     4321 tggcctaatg ttcctccacc accttattaa ccttcaggat acttttcccc taggctgggc
     4381 aggacaacac tatccccttg gtccacaagc tccctcaagg ttggggaatc tttgtttact
     4441 tagcaaatac tgaacataac cttaaagcgg ttacttttga aaacttctca tgctattcta
     4501 ccaacttgga ggcacctatc catgctcatt cccctaatgt agccaatatg gttatctgca
     4561 atgtattggc atctaaaaac tcccttatga aactgccaga cttgttctgg aacatttcaa
     4621 ttacatgcaa aattcaggtt ctcaagttgg aacaagtcta attgacacac ctgcataggt
     4681 tttaaccttg ccctccccct acttcccaac agatttccaa gttttttgag aaggaacctt
     4741 gctctggccc aggctggagt gcaatggcgc catctcggct cactgcaacc tctgcctcct
     4801 gggttcaagt gattctccag cctcctgagt agctgggatt acaagcacct gccaccacac
     4861 ccagcttttt tgtatttttg gtagagacgg ggtttcagtt tgccaggctg gtatcaaacc
     4921 gtgacctcag gtgatccacc cgcattagcc tcccaaagtg ctgggattac aggtgtaagc
     4981 taccataccc agatttccac ggcttttttt ttaagtctca ctctgttacc ctggccggag
     5041 tgtggtggca cgatttcagc tcactgcaag ctccacctcc cgggttcacg ccattctcct
     5101 gcctcggcct cctgagtagc tgggactaca ggtgcctggc taactttttt atatttttag
     5161 tagagacagg gtttcactgt gttagccagg atggtctcgt gatctgcatg ccttggcctc
     5221 ccaaagtgct aggattatag gctcacgcct atattactat atagtggcct atattacagg
     5281 ccactccgcc tggcctccaa atttccaagt ttttaagtct ccatgcaaac aggcataagc
     5341 aagcactcct tggctctaca tttgcaggac aagctggacc accattcaga tgttggtaga
     5401 aatgtaatcc aagtggctat tctctatgca tgtagctcct aggttcaaga gcagtgtggt
     5461 ctgcggattt tctacacaac ctgccataaa tgaaatttaa gcctttggaa atttatagca
     5521 ttttcagcta atttgcatta tttatctctg caagatattg actagaaatc acgtttcaga
     5581 acttctcaga tgaaaacatc atacaaccct taaaactaag ctcataattt aaaaatgtat
     5641 gcagattaat aggcttaaat tgccaggact ttagatagac attaccactt ccaggttaat
     5701 acttttagcg gtttttatgc cttcaatggt ttgaagccct caaccttagt tgaaaactta
     5761 aaaatggcat tgaatggctg ctgcaataag gacacatgaa ttttggctta agtggactag
     5821 gaggactaaa tcttgcttag gcttttaaaa aatgcccacc cactgggtct agggattgag
     5881 gttattttcc tgaattatgg ctaattatgg attacaattc aaggttaaag atacacatat
     5941 agtattctca ggttattcat atgatagcat tttttaagag ccaaagtctc agtcacccag
     6001 gctggagtgc agtggcttga taatggttcg ctacagcctc caacttctat gttaaagtga
     6061 tcctcctacc tcagcctttc aaagtgttgg gattataggc acgtacctat ggccccaaag
     6121 cactttaaca aatgagtaac agacacagtt aaggtagaac ctagcatttt atttagatct
     6181 tcattaaact gttggaattg agaaccagac atacgtaata aacctccaaa aatagatcct
     6241 gaaaggcact ttctgcttag ggcaagcagt catggaataa gcatgtaaac aagctggctt
     6301 ctctgtacca caccagccaa gtcagctttc tccatggcca gccgcaccag ctctgccctc
     6361 ccttctgtta acaccagcca gaccccctgt aggtctaacc caaggttttt ctgtaggaca
     6421 ccttggccta cctgggaatg ctggaaacat gttgttaaag gaatcatggt gttgagagaa
     6481 aaaaaaaaaa tcttttaaaa gctgccatct gaggtgatgg cttctctgta cttacgccat
     6541 accccagaat acaataaata agcaattaga aaacgttcaa gtatgaaggg atttcctcct
     6601 ccccgccaaa agcactgctc tctgaaggaa gctggtttct ctgtagctac accagctgtt
     6661 cagaaagctc attggacctg gttttgaaaa taaaacaaag ttaaaaccc
//
