LOCUS       NM_001195256            1849 bp    mRNA    linear   PRI 09-JUN-2024
DEFINITION  Homo sapiens golgi associated olfactory signaling regulator (GFY),
            transcript variant 1, mRNA.
ACCESSION   NM_001195256 XM_001718302 XM_011526299 XM_928936 XM_936613
VERSION     NM_001195256.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1849)
  AUTHORS   Kaneko-Goto,T., Sato,Y., Katada,S., Kinameri,E., Yoshihara,S.,
            Nishiyori,A., Kimura,M., Fujita,H., Touhara,K., Reed,R.R. and
            Yoshihara,Y.
  TITLE     Goofy coordinates the acuity of olfactory signaling
  JOURNAL   J Neurosci 33 (32), 12987-12996 (2013)
   PUBMED   23926254
REFERENCE   2  (bases 1 to 1849)
  AUTHORS   Grimwood,J., Gordon,L.A., Olsen,A., Terry,A., Schmutz,J.,
            Lamerdin,J., Hellsten,U., Goodstein,D., Couronne,O.,
            Tran-Gyamfi,M., Aerts,A., Altherr,M., Ashworth,L., Bajorek,E.,
            Black,S., Branscomb,E., Caenepeel,S., Carrano,A., Caoile,C.,
            Chan,Y.M., Christensen,M., Cleland,C.A., Copeland,A., Dalin,E.,
            Dehal,P., Denys,M., Detter,J.C., Escobar,J., Flowers,D.,
            Fotopulos,D., Garcia,C., Georgescu,A.M., Glavina,T., Gomez,M.,
            Gonzales,E., Groza,M., Hammon,N., Hawkins,T., Haydu,L., Ho,I.,
            Huang,W., Israni,S., Jett,J., Kadner,K., Kimball,H., Kobayashi,A.,
            Larionov,V., Leem,S.H., Lopez,F., Lou,Y., Lowry,S., Malfatti,S.,
            Martinez,D., McCready,P., Medina,C., Morgan,J., Nelson,K.,
            Nolan,M., Ovcharenko,I., Pitluck,S., Pollard,M., Popkie,A.P.,
            Predki,P., Quan,G., Ramirez,L., Rash,S., Retterer,J., Rodriguez,A.,
            Rogers,S., Salamov,A., Salazar,A., She,X., Smith,D., Slezak,T.,
            Solovyev,V., Thayer,N., Tice,H., Tsai,M., Ustaszewska,A., Vo,N.,
            Wagner,M., Wheeler,J., Wu,K., Xie,G., Yang,J., Dubchak,I.,
            Furey,T.S., DeJong,P., Dickson,M., Gordon,D., Eichler,E.E.,
            Pennacchio,L.A., Richardson,P., Stubbs,L., Rokhsar,D.S.,
            Myers,R.M., Rubin,E.M. and Lucas,S.M.
  TITLE     The DNA sequence and biology of human chromosome 19
  JOURNAL   Nature 428 (6982), 529-535 (2004)
   PUBMED   15057824
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010619.7.
            
            On or before Jul 10, 2020 this sequence version replaced
            XM_011526299.2, NM_001195256.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence because no single transcript was available for the
            full length of the gene. The genomic coordinates used for the
            transcript record were based on transcript and protein alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR12921934.4099638.1,
                                           SRR18074969.1356195.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000610896.3/ ENSP00000478493.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-102               AC010619.7         12559-12660
            103-1306            AC010619.7         13581-14784
            1307-1480           AC010619.7         15117-15290
            1481-1849           AC010619.7         15790-16158
FEATURES             Location/Qualifiers
     source          1..1849
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.33"
     gene            1..1849
                     /gene="GFY"
                     /gene_synonym="Goofy"
                     /note="golgi associated olfactory signaling regulator"
                     /db_xref="GeneID:100507003"
                     /db_xref="HGNC:HGNC:44663"
                     /db_xref="MIM:618696"
     exon            1..102
                     /gene="GFY"
                     /gene_synonym="Goofy"
                     /inference="alignment:Splign:2.1.0"
     exon            103..1306
                     /gene="GFY"
                     /gene_synonym="Goofy"
                     /inference="alignment:Splign:2.1.0"
     CDS             124..1680
                     /gene="GFY"
                     /gene_synonym="Goofy"
                     /note="protein Goofy; Golgi protein in olfactory neurons;
                     Golgi-associated olfactory signaling regulator"
                     /codon_start=1
                     /product="Golgi-associated olfactory signaling regulator
                     precursor"
                     /protein_id="NP_001182185.1"
                     /db_xref="CCDS:CCDS58672.1"
                     /db_xref="GeneID:100507003"
                     /db_xref="HGNC:HGNC:44663"
                     /db_xref="MIM:618696"
                     /translation="MKSFSRILFLVFLLAGLRSKAAPSAPLPLGCGFPDMAHPSETSP
                     LKGASENSKRDRLNPEFPGTPYPEPSKLPHTVSLETFPLDFTEPLNPDLRETPHPESP
                     ETPKADSLTTSISESLDMPKTNLSKMAHPESSETPTPGPTEMPHPGSPETPKPNFSKT
                     SRPEFPETPNTDLMQTTPQESPEILQLNATEVSQAELPETSNTNPTKTPDPKSPEKHD
                     LNSTETPNSEFLQALHPDPSKTPHPESHVTHNPSPTEISQTEFPTTYYQNATDVPRTS
                     DPQISTSLYPETPVPFKDDATALNELSLNPKPGTPAAIQPDSPKLPTSDSPGMVELKA
                     PQNSGPKESNVPPPSARIAGPPALPGRPSQLAPATLRAPQRHSRGEGVNTIIVVERVK
                     ETGVTLVGRPRGAAGGALCLFFAGTALLIGIFVLLWCLYRRAARQRPFAHHRLPDDGD
                     EPVLHLDAPKDPYDLYFYAPDTWVPSHIATKQPPPTPPLPPKLPPPPRGGRPQRLEAL
                     SPATLPNNFV"
     exon            1307..1480
                     /gene="GFY"
                     /gene_synonym="Goofy"
                     /inference="alignment:Splign:2.1.0"
     exon            1481..1849
                     /gene="GFY"
                     /gene_synonym="Goofy"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1829..1834
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GFY"
                     /gene_synonym="Goofy"
                     /note="hexamer: AATAAA"
     polyA_site      1849
                     /gene="GFY"
                     /gene_synonym="Goofy"
                     /note="major polyA site"
ORIGIN      
        1 gagaccctac ctcccaccgc cctgcccaga tctgttctgc aacattcacc gttctctgca
       61 tccagctctg cttatctgct gttaccttgg acaccagagc agctataggt atctgccaga
      121 gctatgaaat cattcagccg gatcctcttc ctcgtcttcc tcctcgccgg cctgaggtcc
      181 aaggccgctc cctcagcccc tctgcctttg ggctgtggct ttccggacat ggcccacccc
      241 tctgagactt cccctctgaa gggtgcttct gaaaattcca aacgagatcg ccttaaccca
      301 gaatttcctg ggactcctta ccctgagcct tccaagctac ctcatacggt ttccctggaa
      361 accttcccac ttgacttcac tgagcccctc aaccctgacc tccgagaaac cccgcaccca
      421 gagtctcctg agacccccaa agctgactca ctcacaacct caatatcaga atccctggac
      481 atgcccaaaa ctaacctctc caaaatggca cacccagagt cttctgagac ccccacacct
      541 ggcccaactg aaatgccaca cccaggatcc cctgagaccc ccaaacctaa cttctccaaa
      601 acttcacgcc cagaatttcc tgagacccca aacactgacc ttatgcaaac tacaccccaa
      661 gaatccccag agattctgca gcttaatgcc actgaagtct cacaggcaga actccccgag
      721 acctcaaaca ctaaccctac caagacccct gaccccaaat ccccagaaaa gcatgacctc
      781 aactccactg agaccccaaa ctctgaattt ctccaagctc tccatcctga cccttctaaa
      841 accccccacc cagaatccca tgtgacccac aatcccagcc ccaccgaaat ttcccaaaca
      901 gaattcccca caacctacta ccaaaatgca acagatgtac ccaggacctc cgaccctcaa
      961 atctccacta gtctctaccc agaaacacct gtgcccttca aggatgacgc cactgctcta
     1021 aatgagctgt ccctgaatcc caaaccagga acacctgcag ccatccagcc cgactcccca
     1081 aaattgccca cttcagattc tccaggaatg gttgagctga aggcccccca gaactctggc
     1141 cctaaggagt ccaacgtccc tcctccctca gcccggattg caggtccccc tgctcttcca
     1201 gggcgcccca gtcagttggc ccctgccact ctgcgggcac cccagaggca cagccgaggt
     1261 gagggagtca acaccatcat cgtggtggag cgagtgaagg agaccggcgt gactctggtg
     1321 gggcgaccac gtggcgcagc aggcggggcc ctctgcctgt tcttcgcggg gaccgcgctg
     1381 ctgatcggca tctttgtgct gctgtggtgt ctttaccgcc gggcagctag acagcggccc
     1441 ttcgcacatc accggcttcc ggacgacgga gatgaaccgg ttctgcattt ggacgccccg
     1501 aaagacccct acgacctcta cttttatgct ccggatacct gggtcccttc ccacatcgcc
     1561 accaagcagc ccccgcccac acctcctctg ccaccaaagc tgcccccgcc gccccgcggg
     1621 ggtcgcccgc agcgtctgga ggccctgtcc cccgccacgc tccccaacaa cttcgtgtga
     1681 gccccaccga gttctgccgg acctgcacat ccccacagtg aaggaaaacc ctgcgcttct
     1741 ggtatgctta gctagagtag tgccccggat aaagggtcta atatacagag atgcttgcgc
     1801 tgtgatcaga gaacaaggtc tgagaccgaa taaatatcat gttcccatg
//
