LOCUS       NM_182833               2617 bp    mRNA    linear   PRI 15-FEB-2024
DEFINITION  Homo sapiens glycerophosphodiester phosphodiesterase domain
            containing 4 (GDPD4), mRNA.
ACCESSION   NM_182833
VERSION     NM_182833.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2617)
  AUTHORS   Kaewsutthi,S., Santiprabhob,J., Phonrat,B., Tungtrongchitr,A.,
            Lertrit,P. and Tungtrongchitr,R.
  TITLE     Exome sequencing in Thai patients with familial obesity
  JOURNAL   Genet Mol Res 15 (2) (2016)
   PUBMED   27421018
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP002827.4 and AP001855.4.
            
            On Jan 30, 2020 this sequence version replaced NM_182833.2.
            
            ##Evidence-Data-START##
            CDS exon combination :: AY326450.1 [ECO:0000331]
            RNAseq introns       :: partial sample support SAMEA1968968,
                                    SAMEA2148874 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000315938.5/ ENSP00000320815.4
            RefSeq Select criteria :: based on manual assertion, conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-82                AP002827.4         43663-43744         c
            83-285              AP002827.4         29276-29478         c
            286-388             AP002827.4         27143-27245         c
            389-482             AP002827.4         21364-21457         c
            483-542             AP002827.4         18219-18278         c
            543-641             AP002827.4         13353-13451         c
            642-735             AP002827.4         13188-13281         c
            736-813             AP002827.4         11941-12018         c
            814-959             AP002827.4         10982-11127         c
            960-1042            AP002827.4         10515-10597         c
            1043-1199           AP002827.4         444-600             c
            1200-1421           AP001855.4         55514-55735         c
            1422-1576           AP001855.4         53927-54081         c
            1577-1724           AP001855.4         43258-43405         c
            1725-1807           AP001855.4         39383-39465         c
            1808-1860           AP001855.4         38097-38149         c
            1861-2617           AP001855.4         26791-27547         c
FEATURES             Location/Qualifiers
     source          1..2617
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q13.5"
     gene            1..2617
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /note="glycerophosphodiester phosphodiesterase domain
                     containing 4"
                     /db_xref="GeneID:220032"
                     /db_xref="HGNC:HGNC:24849"
     exon            1..82
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     exon            83..285
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     exon            286..388
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     CDS             336..1898
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /note="GDPD domain containing protein; ugpQ;
                     glycerophosphodiester phosphodiesterase 6"
                     /codon_start=1
                     /product="glycerophosphodiester phosphodiesterase
                     domain-containing protein 4"
                     /protein_id="NP_878253.1"
                     /db_xref="CCDS:CCDS8249.1"
                     /db_xref="GeneID:220032"
                     /db_xref="HGNC:HGNC:24849"
                     /translation="MLLFLWIETSSEYFNFDWVTFLGTGYWFFWSIFILSLARILTAY
                     SSLLLLLGFLLLWERIELYLHLCHKILILLVILLCVILMFIICKFWKERWLVAGLSMQ
                     IFAPYVHLVSITVMVILFWPVAFYVACLEREVRMRRYRMTHSEKKRLKQCNVITRLRG
                     LQVPVGLPFLLILLGLYLMPLGIYSPCIQEKENLGPKPTIFGHRGAPMLGPENTMMSF
                     EKAVEHGAHGLETDIHLSYDHVPFLMHDFDLKRTTNIGEVQPESACENPAFFNWDFLS
                     TLNAGKWFVKPELRPFYNMKPLSEADKERARNQSIPTLADLLTLAEKERKFVIFDLHR
                     PPPKHPLRHTFVRQVVSVILASKIEQHLIFWLPAHDRQYVRSVAPGFQHVGRLVSIET
                     LAKNNISIINVDYKKLFPNGLRDYKAANIHINVYTVNEPWLFSLAWCSRINSVTTDNI
                     GLLSQLDHPHFFMTPKFYVFMWLLADIISVLFIVAIFCFHWRRETEKEKLFETSSTRT
                     DTQSGSKNEEDR"
     exon            389..482
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     exon            483..542
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     exon            543..641
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     exon            642..735
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     exon            736..813
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     exon            814..959
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     exon            960..1042
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     exon            1043..1199
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     exon            1200..1421
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     exon            1422..1576
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     exon            1577..1724
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     exon            1725..1807
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     exon            1808..1860
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     exon            1861..2617
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2295..2300
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /note="hexamer: AATATA"
     polyA_site      2315
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /note="major polyA site"
     regulatory      2596..2601
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /note="hexamer: AGTAAA"
     polyA_site      2617
                     /gene="GDPD4"
                     /gene_synonym="GDE6"
                     /note="major polyA site"
ORIGIN      
        1 cttccagcca ggcgtccatc ttaagagacg ctggtctcct caggcgtgaa gattggattt
       61 gggttgggac tgggaagtct cgctaaaggg tgaatcatgt ttaagaaggt caacaggatt
      121 gagcacaaga ggaataagac agaaaaacca aaaaagctta atccatggat tccacgcatc
      181 ttcaaccaca aatgctttgt caccttcctt actggctgct atagttgcct ctggaaattc
      241 agacaatggg aaaaaactaa agttggattt tgttgctgca cttggaaaga gcaattattt
      301 tgccgtgcct ggtaatttca tttgtcttgt ctctgatgtt gctgttcctg tggatagaaa
      361 catccagtga atactttaac tttgactggg tcacttttct aggaacagga tactggtttt
      421 tctggtctat ttttattctg agtttagcta ggatcctgac tgcctactct tcattgctgt
      481 tgttacttgg atttttgttg ctttgggaaa ggattgaact atacctgcac ttgtgtcata
      541 agatcctgat tctgctagtg attcttctgt gtgtcatttt aatgttcatt atatgcaaat
      601 tctggaaaga aaggtggctg gtagctgggc tgtcaatgca gatctttgct ccctacgtgc
      661 acctggtcag cataactgtg atggttatcc ttttctggcc tgtggccttc tacgtggcat
      721 gtttggaaag agaagttaga atgagaagat acaggatgac acattctgag aaaaaaagac
      781 tcaagcaatg taatgtaatc acaaggttaa gaggtctaca agtgcctgtt ggattaccct
      841 ttcttcttat ccttttaggt ctctatttga tgccactggg gatttattct ccctgcattc
      901 aggagaagga gaatttgggg cccaagccaa ccatctttgg acatagaggt gcacccatgt
      961 tggggcctga gaataccatg atgtcctttg agaaagctgt tgaacatgga gcccatggat
     1021 tggagactga tatacactta agttatgatc atgtgccttt cctcatgcat gactttgacc
     1081 tgaaaagaac aaccaatatt ggggaagttc agccagaatc tgcctgcgag aaccctgcct
     1141 tcttcaactg ggatttccta tcgactctga atgcaggcaa atggtttgta aaaccagagc
     1201 tcaggccatt ttacaatatg aaacctctat cagaggcaga taaagaaaga gcaagaaatc
     1261 agtcaattcc aacactagct gatttattga cacttgcaga gaaggaaaga aaatttgtga
     1321 tatttgatct tcatcgccct ccaccaaaac atcctctcag acacacattt gtccgccaag
     1381 tagtaagcgt gatccttgcc tctaaaatcg agcaacatct gattttttgg ttgccagctc
     1441 atgataggca atacgtcagg tccgtggctc ctggttttca gcatgtgggc cgtttagtat
     1501 ccattgaaac ccttgctaaa aacaatatca gtataataaa tgttgactac aagaagttgt
     1561 tccctaatgg gttaagagat tataaagcag ctaacatcca tatcaacgta tacaccgtca
     1621 atgagccttg gcttttctca ctggcctggt gctccaggat taactcagtg accacagaca
     1681 acattgggct cctgagtcag cttgatcacc ctcacttctt catgacacca aagttctatg
     1741 tgttcatgtg gctccttgca gatatcattt ctgtgctttt tattgttgcc atattttgtt
     1801 ttcactggcg gagagagact gaaaaagaaa aattgtttga aacctccagc actcgcacag
     1861 atactcagag tggaagtaag aatgaggaag atagatagat agatagattt gcacatagcc
     1921 atgaaacctc ctgtccgagt tgtggaaggt ccttggactc tagcagccct ctacccggct
     1981 ctacccaaga gtggaaagga acaccaaggc catttcaatt ttgcagcacc atccaagaaa
     2041 ctactaccta tcaagaatgc tgtcacacct ttgaagcctg gcaagcatga gattcaacca
     2101 ccgatgccca ccgtggtctt tgaactcacc caagcaccca ccaggcaggc tacaagtgag
     2161 gctacctttc aaactacatt gcccaccctg aaggtggata agccaaccat gccctccata
     2221 gaggtcccct atccttaaat aagagacctc taagagatcc ccatggctga atactccaaa
     2281 taatcctatg tcacaatata ttccattgca tctgacatag ccttctgtgt ttccaaagaa
     2341 gaattagcca catctcccct gcttcttcct ctctctgcct aagggtggtg atggtgggga
     2401 gtggttgata aaggcacaca gaagggccac ggaggctctc aggggaacca ttgtgctctc
     2461 gctatcaaga atgcatctca aggggctagg caaggggaaa actgctgtgt gtggtcttgg
     2521 aactggttgc tgtcaggttt atctcatcct aacacctcca taatattttc tgctaaagga
     2581 gtgactgtgc atataagtaa aggcaacctc tcaggaa
//
