LOCUS       NM_153364               1864 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens golgi associated RAB2 interactor family member 6
            (GARIN6), mRNA.
ACCESSION   NM_153364
VERSION     NM_153364.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1864)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB055853.1, BC031221.1, AC141554.5, AA401734.1, DB514813.1 and
            AW181907.1.
            
            On Nov 22, 2018 this sequence version replaced NM_153364.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.281509.1,
                                           SRR5189667.183011.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000324341.2/ ENSP00000315247.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-545               DB055853.1         4-548
            546-1493            BC031221.1         546-1493
            1494-1494           AC141554.5         54822-54822
            1495-1616           BC031221.1         1495-1616
            1617-1799           AA401734.1         1-183               c
            1800-1863           DB514813.1         308-371
            1864-1864           AW181907.1         24-24               c
FEATURES             Location/Qualifiers
     source          1..1864
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q23.1"
     gene            1..1864
                     /gene="GARIN6"
                     /gene_synonym="FAM71C"
                     /note="golgi associated RAB2 interactor family member 6"
                     /db_xref="GeneID:196472"
                     /db_xref="HGNC:HGNC:28594"
     exon            1..1037
                     /gene="GARIN6"
                     /gene_synonym="FAM71C"
                     /inference="alignment:Splign:2.1.0"
     CDS             423..1148
                     /gene="GARIN6"
                     /gene_synonym="FAM71C"
                     /note="protein FAM71C; family with sequence similarity 71
                     member C; Golgi associated RAB2 interactor protein 6"
                     /codon_start=1
                     /product="Golgi-associated RAB2 interactor protein 6"
                     /protein_id="NP_699195.1"
                     /db_xref="CCDS:CCDS9072.1"
                     /db_xref="GeneID:196472"
                     /db_xref="HGNC:HGNC:28594"
                     /translation="MEDCCMLPYYTAQSSPAMGMFNTSMGKLQRQLYKGEYTIFRYAP
                     MFESDFIQISKRGEVIDVHNRARMVTMGIVRTSPCLTLPDVMLLARPAAVCDNARCGP
                     ATQKRESPPAEILELTRLLPLMFVKITIHNSVKKQLHLKLATGRSFYLQLCPPSDASE
                     DLFVHWENLVYILRPPVEAYSDTRAILAGNTLDSSVLEEVQRSPVGYAMKFCEEKEQF
                     RISRLHMNAEMFGSTYCDYTIEI"
     exon            1038..1864
                     /gene="GARIN6"
                     /gene_synonym="FAM71C"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1136..1141
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GARIN6"
                     /gene_synonym="FAM71C"
                     /note="hexamer: AATAGA"
     polyA_site      1154
                     /gene="GARIN6"
                     /gene_synonym="FAM71C"
     regulatory      1779..1784
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GARIN6"
                     /gene_synonym="FAM71C"
                     /note="hexamer: AATAAA"
     polyA_site      1799
                     /gene="GARIN6"
                     /gene_synonym="FAM71C"
                     /note="major polyA site"
     regulatory      1844..1849
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GARIN6"
                     /gene_synonym="FAM71C"
                     /note="hexamer: AATAAA"
     polyA_site      1864
                     /gene="GARIN6"
                     /gene_synonym="FAM71C"
                     /note="major polyA site"
ORIGIN      
        1 agcagtggat ggttcaggtt gggaagaaga gcagtgggat tgccagttaa ggttgtggaa
       61 tcaaagagca aaggctgttg tgaagtggaa tatcaggctc aaatggaggt ccctcccgaa
      121 tgagcactga cacctgtgtg cccggacatc cacgagggcc ccaacacctg tgctcctgac
      181 agctccatgc actaagcagg gcacagtctg gatccagggg actgactgtc tctggcattg
      241 agcggttggt aatcaatacc ccaccctccc tgttctcagt cacttgggga caaaaaagaa
      301 agcctgcaga acacgactgc tggcccacct gccagagtag ccaaggaaac aggatgcccg
      361 ctaaagcatg ttaaggaagg tgtggagcag ctgctgggaa ctgtcttgat ttaaaggaag
      421 acatggagga ctgctgtatg ctaccgtatt acacggccca aagcagcccc gcaatgggca
      481 tgtttaacac ctccatgggg aagctgcagc ggcaactgta caaaggcgag tatactatat
      541 tcaggtatgc acccatgttt gagagcgact ttatccagat cagcaaaaga ggagaagtga
      601 ttgacgtgca caaccgtgcc cgaatggtaa caatgggcat cgttcgcacc agcccctgcc
      661 tcacactacc tgatgtcatg ctgctggccc gaccagctgc tgtctgtgac aatgccaggt
      721 gtggtcctgc cacccagaaa agagaaagtc cgcctgcaga gatcttagaa ctaaccaggc
      781 tgcttccctt gatgtttgtg aaaataacca tccacaacag cgtaaaaaaa cagctccacc
      841 tgaagcttgc cacgggccgc tctttttatc ttcagctgtg tcctccatcg gatgcaagtg
      901 aagacctttt tgttcactgg gaaaaccttg tttacatcct gagaccacca gtggaggctt
      961 acagtgatac cagggctatc ctagctggga acacattgga ctcatctgtg ttggaggaag
     1021 tgcagaggag cccagtggga tatgccatga agttttgtga agagaaggag caattcagaa
     1081 tcagtagact tcacatgaat gctgaaatgt ttgggtccac ctattgtgat tatacaatag
     1141 agatatgaat ccaacatacc tcccacatat actacgttca agagttcaca cacccctgca
     1201 gtcataaaac ctatagtgcc tgatgaaggg gcagggtagc aacagcagta gtgatgacag
     1261 taagcaccac cacaggtacc atggatgtgg ctgcaaccaa gtctgcagac tcaggagaga
     1321 aacacagcac tggcaaaagc agccttcaga ggtccaggag gaagtatagc cagcatggct
     1381 attagtgggt gcttccatgt cttaatcttg ttatagcaag ggctgcatgc acattcttgt
     1441 cctaaaaggg tacttcaagc atatcagtaa gtgctactgg cctctcccta gagagcagta
     1501 tgaatgtggt ggctacagga gcagagagat actgagaagg ctgttgcatt gacagtatct
     1561 ctctgctact caaaggctga ctctctgcta ctcagcattg ggagtcagtt atctcaactc
     1621 tgcaggatga ggccacatgc gtgaatggga tggaagccag agggtctcta cctagctgga
     1681 ttgactctgc agtaataacc tcaaagccca gtactacaca tggtgcagag gtggacatct
     1741 cacctaagac tgtggagggg aacaatgtga ttcaccataa taaaatccat caactcaaat
     1801 tatctgctct aataacatat gctctattga caggaagggt agcaataaaa ctaatggcaa
     1861 ttta
//
