LOCUS       NM_130899               2515 bp    mRNA    linear   PRI 28-FEB-2024
DEFINITION  Homo sapiens golgi associated RAB2 interactor family member 3
            (GARIN3), mRNA.
ACCESSION   NM_130899
VERSION     NM_130899.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2515)
  AUTHORS   Petit,F.G., Kervarrec,C., Jamin,S.P., Smagulova,F., Hao,C.,
            Becker,E., Jegou,B., Chalmel,F. and Primig,M.
  TITLE     Combining RNA and protein profiling data with network interactions
            identifies genes associated with spermatogenesis in mouse and human
  JOURNAL   Biol Reprod 92 (3), 71 (2015)
   PUBMED   25609838
REFERENCE   2  (bases 1 to 2515)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   3  (bases 1 to 2515)
  AUTHORS   Fukuda,M., Kanno,E., Ishibashi,K. and Itoh,T.
  TITLE     Large scale screening for novel rab effectors reveals unexpected
            broad Rab binding specificity
  JOURNAL   Mol Cell Proteomics 7 (6), 1031-1042 (2008)
   PUBMED   18256213
REFERENCE   4  (bases 1 to 2515)
  AUTHORS   van Koningsbruggen,S., Straasheijm,K.R., Sterrenburg,E., de
            Graaf,N., Dauwerse,H.G., Frants,R.R. and van der Maarel,S.M.
  TITLE     FRG1P-mediated aggregation of proteins involved in pre-mRNA
            processing
  JOURNAL   Chromosoma 116 (1), 53-64 (2007)
   PUBMED   17103222
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC025409.1 and AC010609.7.
            
            On Nov 22, 2018 this sequence version replaced NM_130899.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK057543.1, BC022035.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000302938.4/ ENSP00000305596.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2029              BC025409.1         6-2034
            2030-2515           AC010609.7         43707-44192         c
FEATURES             Location/Qualifiers
     source          1..2515
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q33.3"
     gene            1..2515
                     /gene="GARIN3"
                     /gene_synonym="FAM71B; GARI-L3"
                     /note="golgi associated RAB2 interactor family member 3"
                     /db_xref="GeneID:153745"
                     /db_xref="HGNC:HGNC:28397"
                     /db_xref="MIM:619883"
     exon            1..702
                     /gene="GARIN3"
                     /gene_synonym="FAM71B; GARI-L3"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..1914
                     /gene="GARIN3"
                     /gene_synonym="FAM71B; GARI-L3"
                     /note="protein FAM71B; testicular tissue protein Li 68;
                     family with sequence similarity 71 member B; Golgi
                     associated RAB2 interactor protein 3; golgi associated
                     RAB2B interactor family member 3"
                     /codon_start=1
                     /product="Golgi-associated RAB2 interactor protein 3"
                     /protein_id="NP_570969.2"
                     /db_xref="CCDS:CCDS4335.1"
                     /db_xref="GeneID:153745"
                     /db_xref="HGNC:HGNC:28397"
                     /db_xref="MIM:619883"
                     /translation="MSNESCLPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYA
                     PMFESNFIQINKKGEVIDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRW
                     GRFAKGRGRRPVKTLELTRLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDT
                     REDLFCYWEKLVYLLRPPVESYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLY
                     KPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTAT
                     GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA
                     NISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG
                     PAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAG
                     ESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKE
                     SRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE
                     KQNIEAKVEKAQGGQELEMISGTMTSEKTEMIVFETKSI"
     exon            703..2515
                     /gene="GARIN3"
                     /gene_synonym="FAM71B; GARI-L3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1999..2004
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GARIN3"
                     /gene_synonym="FAM71B; GARI-L3"
                     /note="hexamer: AATAAA"
     polyA_site      2029
                     /gene="GARIN3"
                     /gene_synonym="FAM71B; GARI-L3"
                     /note="major polyA site"
     regulatory      2494..2499
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GARIN3"
                     /gene_synonym="FAM71B; GARI-L3"
                     /note="hexamer: AATAAA"
     polyA_site      2515
                     /gene="GARIN3"
                     /gene_synonym="FAM71B; GARI-L3"
ORIGIN      
        1 agaagtcctg tagggagatg ggcagttacc ttctctccgt ctctctctcg gggactctat
       61 ttgtggctgg tggagctgtc ttaaacgaag agaaccatga gcaatgaatc ttgtttacct
      121 tattacacag cccacagcta ctcttcaatg agtgcgttca aaacctccat gggggacctg
      181 caacgacaat tgtacaacag aggagagtac aacattttca agtatgcacc aatgttcgag
      241 agtaatttta ttcagataaa caaaaaggga gaggtgattg atgtacacaa ccgtgtccga
      301 atggtgacag tgggcatcgt ctgcaccagc cccatcctcc cactgcctga cgtcatggtt
      361 ctggcccaac caactaaaat ctgtgaacag catgtcagat ggggccggtt tgccaagggg
      421 agaggtcgca ggcccgtcaa gactctagag ctcacgagac tgcttccctt gaaatttgtg
      481 aagatctcca tccacgatca tgagaaacag cagctgcgcc tgaaactcgc cactggccgt
      541 actttttatc tgcagttgtg tccctcttct gacacacggg aagatctctt ttgctattgg
      601 gaaaaacttg tctatctcct gaggccacca gtagagagtt actgcagtac cccaacactt
      661 ctatctgggg acgcaccacc cgaagacaac aaaagcctag tggctgcaga gctccacaga
      721 gaaggggatc agagtgagac tgggctctac aagccttgtg atgtatctgc agccacctct
      781 tctgcttatg ctgggggaga gggaatccaa catgcctccc acggaacggc tagtgcggct
      841 tctccatcca cgagcactcc aggggctgct gaaggaggag cagcaaggac agcaggtggc
      901 atggcagtgg caggaacagc aacaggacct agaacagatg tggcaatagc aggggcagca
      961 atgagtcctg caacaggtgc tatgagcata gcaacaacca aatctgcagg cccaggtcaa
     1021 gtgaccacag cgctggcggg agcagctatc aaaaatccag gagaaaatga atccagcaag
     1081 tccatggcag gtgctgccaa catatcctca gagggtatta gcttggcctt ggtgggtgct
     1141 gcaagcacct ccttggaagg tacttccacc tcgatggcgg gggccgccag tctctcccaa
     1201 gacagcagct tgagtgcggc gtttgcaggc agtattacga ccagcaagtg tgcagcagaa
     1261 agaactgaag gaccagcagt gggacccctc atctccacct tgcaaagcga aggctacatg
     1321 agtgaacgag atggaagcca gaaagtttcc cagcccagtg ctgaagtctg gaatgaaaac
     1381 aaggaaagaa gagaaaagaa ggacagacat cccagtagga aaagttctca tcaccgcaag
     1441 gcaggtgaaa gtcaccgcag gagagcgggg gacaagaatc agaaagcgtc ttcccaccgg
     1501 tccgcatctg gccataaaaa cacgagagat gacaaaaaag aaaaagggta cagcaacgta
     1561 aggggcaagc gacatggctc ctctcgcaag agctccaccc acagctccac caaaaaggag
     1621 tcgagaacaa ctcaggaact ggggaagaac caatctgcat ctagcacagg agctttacaa
     1681 aagaaagcca gtaagatcag ctctttttta aggagcctca gggccactcc tggttcaaaa
     1741 acaagggtca catcacatga cagagaggta gatatcgtgg ctaagatggt ggagaagcaa
     1801 aacatagagg ccaaagtgga gaaagcccag ggtggccagg agctggagat gatcagtggc
     1861 actatgacat ccgagaagac ggagatgatc gtctttgaaa ccaaatccat ttaaagagga
     1921 gccagggcta caaccgccca gggatctgga agtatcccta gaggagccca tcccagcttt
     1981 ctttactgca gttcaaataa taaaggaaat cgtacaactc caaaagaaat acaatctcct
     2041 gcttgaattt ttctgcccat agcctggtgg tgacctcaca gtggcttctg tgatggtggc
     2101 tatgctacag ctggagaccc cagcctccag gcaagtagag ctccaccacc cgcccacggc
     2161 cagcagagcc aacgtgagtg ttcagctttg cctcaatccc ttttgcttcc ccgagactgt
     2221 caaagccaca gactaagagc tgggatgcat ggccaccacc atgtcccctc gcccattctc
     2281 ctcttttccc tgaatgcccc tgaacatgga cattcagtcc agttcttagc ctatgcagag
     2341 acaggattca catcccctca ggggatattc agggtaggaa ggagcaatac agcagtattt
     2401 gtaggcaatt agaataggaa atctattctt ctagatcagg aattggcaaa tcatgttctg
     2461 aggtccaaat cttaccagct gcctggattt gtaaataaag ttttattgga acata
//
