LOCUS       NM_198516               2503 bp    mRNA    linear   PRI 11-FEB-2025
DEFINITION  Homo sapiens polypeptide N-acetylgalactosaminyltransferase 18
            (GALNT18), transcript variant 1, mRNA.
ACCESSION   NM_198516 XM_350823
VERSION     NM_198516.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2503)
  AUTHORS   Jia,W., Zou,X., Xu,Z., Bai,L., Shan,A., Li,Y., Shi,J., Yang,F.,
            Ding,C., Narimatsu,H. and Zhang,Y.
  TITLE     Polypeptide N-acetylgalactosaminyltransferase 18 retains in
            endoplasmic reticulum depending on its luminal regions interacting
            with ER resident UGGT1, PLOD3 and LPCAT1
  JOURNAL   Glycobiology 31 (8), 947-958 (2021)
   PUBMED   33909026
  REMARK    GeneRIF: Polypeptide N-acetylgalactosaminyltransferase 18 retains
            in endoplasmic reticulum depending on its luminal regions
            interacting with ER resident UGGT1, PLOD3 and LPCAT1.
REFERENCE   2  (bases 1 to 2503)
  AUTHORS   Wang,J., Bansal,A.T., Martin,M., Germer,S., Benayed,R., Essioux,L.,
            Lee,J.S., Begovich,A., Hemmings,A., Kenwright,A., Taylor,K.E.,
            Upmanyu,R., Cutler,P., Harari,O., Marchini,J., Criswell,L.A. and
            Platt,A.
  TITLE     Genome-wide association analysis implicates the involvement of
            eight loci with response to tocilizumab for the treatment of
            rheumatoid arthritis
  JOURNAL   Pharmacogenomics J 13 (3), 235-241 (2013)
   PUBMED   22491018
REFERENCE   3  (bases 1 to 2503)
  AUTHORS   Raman,J., Guan,Y., Perrine,C.L., Gerken,T.A. and Tabak,L.A.
  TITLE     UDP-N-acetyl-alpha-D-galactosamine:polypeptide
            N-acetylgalactosaminyltransferases: completion of the family tree
  JOURNAL   Glycobiology 22 (6), 768-777 (2012)
   PUBMED   22186971
  REMARK    Erratum:[Glycobiology. 2015 Apr;25(4):465. doi:
            10.1093/glycob/cwv003.. PMID: 25715345]
REFERENCE   4  (bases 1 to 2503)
  AUTHORS   Li,X., Wang,J., Li,W., Xu,Y., Shao,D., Xie,Y., Xie,W., Kubota,T.,
            Narimatsu,H. and Zhang,Y.
  TITLE     Characterization of ppGalNAc-T18, a member of the
            vertebrate-specific Y subfamily of
            UDP-N-acetyl-alpha-D-galactosamine:polypeptide
            N-acetylgalactosaminyltransferases
  JOURNAL   Glycobiology 22 (5), 602-615 (2012)
   PUBMED   22171061
REFERENCE   5  (bases 1 to 2503)
  AUTHORS   Palmer,N.D., McDonough,C.W., Hicks,P.J., Roh,B.H., Wing,M.R.,
            An,S.S., Hester,J.M., Cooke,J.N., Bostrom,M.A., Rudock,M.E.,
            Talbert,M.E., Lewis,J.P., Ferrara,A., Lu,L., Ziegler,J.T.,
            Sale,M.M., Divers,J., Shriner,D., Adeyemo,A., Rotimi,C.N., Ng,M.C.,
            Langefeld,C.D., Freedman,B.I., Bowden,D.W., Voight,B.F.,
            Scott,L.J., Steinthorsdottir,V., Morris,A.P., Dina,C., Welch,R.P.,
            Zeggini,E., Huth,C., Aulchenko,Y.S., Thorleifsson,G.,
            McCulloch,L.J., Ferreira,T., Grallert,H., Amin,N., Wu,G.,
            Willer,C.J., Raychaudhuri,S., McCarroll,S.A., Langenberg,C.,
            Hofmann,O.M., Dupuis,J., Qi,L., Segre,A.V., van Hoek,M.,
            Navarro,P., Ardlie,K., Balkau,B., Benediktsson,R., Bennett,A.J.,
            Blagieva,R., Boerwinkle,E., Bonnycastle,L.L., Bostrom,K.B.,
            Bravenboer,B., Bumpstead,S., Burtt,N.P., Charpentier,G.,
            Chines,P.S., Cornelis,M., Couper,D.J., Crawford,G., Doney,A.S.,
            Elliott,K.S., Elliott,A.L., Erdos,M.R., Fox,C.S., Franklin,C.S.,
            Ganser,M., Gieger,C., Grarup,N., Green,T., Griffin,S., Groves,C.J.,
            Guiducci,C., Hadjadj,S., Hassanali,N., Herder,C., Isomaa,B.,
            Jackson,A.U., Johnson,P.R., Jorgensen,T., Kao,W.H., Klopp,N.,
            Kong,A., Kraft,P., Kuusisto,J., Lauritzen,T., Li,M., Lieverse,A.,
            Lindgren,C.M., Lyssenko,V., Marre,M., Meitinger,T., Midthjell,K.,
            Morken,M.A., Narisu,N., Nilsson,P., Owen,K.R., Payne,F.,
            Perry,J.R., Petersen,A.K., Platou,C., Proenca,C., Prokopenko,I.,
            Rathmann,W., Rayner,N.W., Robertson,N.R., Rocheleau,G., Roden,M.,
            Sampson,M.J., Saxena,R., Shields,B.M., Shrader,P., Sigurdsson,G.,
            Sparso,T., Strassburger,K., Stringham,H.M., Sun,Q., Swift,A.J.,
            Thorand,B., Tichet,J., Tuomi,T., van Dam,R.M., van Haeften,T.W.,
            van Herpt,T., van Vliet-Ostaptchouk,J.V., Walters,G.B.,
            Weedon,M.N., Wijmenga,C., Witteman,J., Bergman,R.N., Cauchi,S.,
            Collins,F.S., Gloyn,A.L., Gyllensten,U., Hansen,T., Hide,W.A.,
            Hitman,G.A., Hofman,A., Hunter,D.J., Hveem,K., Laakso,M.,
            Mohlke,K.L., Morris,A.D., Palmer,C.N., Pramstaller,P.P., Rudan,I.,
            Sijbrands,E., Stein,L.D., Tuomilehto,J., Uitterlinden,A.,
            Walker,M., Wareham,N.J., Watanabe,R.M., Abecasis,G.R., Boehm,B.O.,
            Campbell,H., Daly,M.J., Hattersley,A.T., Hu,F.B., Meigs,J.B.,
            Pankow,J.S., Pedersen,O., Wichmann,H.E., Barroso,I., Florez,J.C.,
            Frayling,T.M., Groop,L., Sladek,R., Thorsteinsdottir,U.,
            Wilson,J.F., Illig,T., Froguel,P., van Duijn,C.M., Stefansson,K.,
            Altshuler,D., Boehnke,M., McCarthy,M.I., Soranzo,N., Wheeler,E.,
            Glazer,N.L., Bouatia-Naji,N., Magi,R., Randall,J., Johnson,T.,
            Elliott,P., Rybin,D., Henneman,P., Dehghan,A., Hottenga,J.J.,
            Song,K., Goel,A., Egan,J.M., Lajunen,T., Doney,A., Kanoni,S.,
            Cavalcanti-Proenca,C., Kumari,M., Timpson,N.J., Zabena,C.,
            Ingelsson,E., An,P., O'Connell,J., Luan,J., Elliott,A.,
            McCarroll,S.A., Roccasecca,R.M., Pattou,F., Sethupathy,P.,
            Ariyurek,Y., Barter,P., Beilby,J.P., Ben-Shlomo,Y., Bergmann,S.,
            Bochud,M., Bonnefond,A., Borch-Johnsen,K., Bottcher,Y., Brunner,E.,
            Bumpstead,S.J., Chen,Y.D., Chines,P., Clarke,R., Coin,L.J.,
            Cooper,M.N., Crisponi,L., Day,I.N., de Geus,E.J., Delplanque,J.,
            Fedson,A.C., Fischer-Rosinsky,A., Forouhi,N.G., Frants,R.,
            Franzosi,M.G., Galan,P., Goodarzi,M.O., Graessler,J., Grundy,S.,
            Gwilliam,R., Hallmans,G., Hammond,N., Han,X., Hartikainen,A.L.,
            Hayward,C., Heath,S.C., Hercberg,S., Hicks,A.A., Hillman,D.R.,
            Hingorani,A.D., Hui,J., Hung,J., Jula,A., Kaakinen,M., Kaprio,J.,
            Kesaniemi,Y.A., Kivimaki,M., Knight,B., Koskinen,S., Kovacs,P.,
            Kyvik,K.O., Lathrop,G.M., Lawlor,D.A., Le Bacquer,O., Lecoeur,C.,
            Li,Y., Mahley,R., Mangino,M., Manning,A.K., Martinez-Larrad,M.T.,
            McAteer,J.B., McPherson,R., Meisinger,C., Melzer,D., Meyre,D.,
            Mitchell,B.D., Mukherjee,S., Naitza,S., Neville,M.J., Oostra,B.A.,
            Orru,M., Pakyz,R., Paolisso,G., Pattaro,C., Pearson,D., Peden,J.F.,
            Pedersen,N.L., Perola,M., Pfeiffer,A.F., Pichler,I., Polasek,O.,
            Posthuma,D., Potter,S.C., Pouta,A., Province,M.A., Psaty,B.M.,
            Rayner,N.W., Rice,K., Ripatti,S., Rivadeneira,F., Rolandsson,O.,
            Sandbaek,A., Sandhu,M., Sanna,S., Sayer,A.A., Scheet,P.,
            Seedorf,U., Sharp,S.J., Shields,B., Sijbrands,E.J., Silveira,A.,
            Simpson,L., Singleton,A., Smith,N.L., Sovio,U., Swift,A.,
            Syddall,H., Syvanen,A.C., Tanaka,T., Tonjes,A., Uitterlinden,A.G.,
            van Dijk,K.W., Varma,D., Visvikis-Siest,S., Vitart,V.,
            Vogelzangs,N., Waeber,G., Wagner,P.J., Walley,A., Ward,K.L.,
            Watkins,H., Wild,S.H., Willemsen,G., Witteman,J.C., Yarnell,J.W.,
            Zelenika,D., Zethelius,B., Zhai,G., Zhao,J.H., Zillikens,M.C.,
            Borecki,I.B., Loos,R.J., Meneton,P., Magnusson,P.K., Nathan,D.M.,
            Williams,G.H., Silander,K., Salomaa,V., Smith,G.D., Bornstein,S.R.,
            Schwarz,P., Spranger,J., Karpe,F., Shuldiner,A.R., Cooper,C.,
            Dedoussis,G.V., Serrano-Rios,M., Lind,L., Palmer,L.J., Franks,P.W.,
            Ebrahim,S., Marmot,M., Kao,W.H., Pramstaller,P.P., Wright,A.F.,
            Stumvoll,M., Hamsten,A., Buchanan,T.A., Valle,T.T., Rotter,J.I.,
            Siscovick,D.S., Penninx,B.W., Boomsma,D.I., Deloukas,P.,
            Spector,T.D., Ferrucci,L., Cao,A., Scuteri,A., Schlessinger,D.,
            Uda,M., Ruokonen,A., Jarvelin,M.R., Waterworth,D.M.,
            Vollenweider,P., Peltonen,L., Mooser,V. and Sladek,R.
  CONSRTM   DIAGRAM Consortium; MAGIC Investigators
  TITLE     A genome-wide association search for type 2 diabetes genes in
            African Americans
  JOURNAL   PLoS One 7 (1), e29202 (2012)
   PUBMED   22238593
REFERENCE   6  (bases 1 to 2503)
  AUTHORS   Xu,J., Zheng,S.L., Isaacs,S.D., Wiley,K.E., Wiklund,F., Sun,J.,
            Kader,A.K., Li,G., Purcell,L.D., Kim,S.T., Hsu,F.C., Stattin,P.,
            Hugosson,J., Adolfsson,J., Walsh,P.C., Trent,J.M., Duggan,D.,
            Carpten,J., Gronberg,H. and Isaacs,W.B.
  TITLE     Inherited genetic variant predisposes to aggressive but not
            indolent prostate cancer
  JOURNAL   Proc Natl Acad Sci U S A 107 (5), 2136-2140 (2010)
   PUBMED   20080650
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   7  (bases 1 to 2503)
  AUTHORS   Trynka,G., Zhernakova,A., Romanos,J., Franke,L., Hunt,K.A.,
            Turner,G., Bruinenberg,M., Heap,G.A., Platteel,M., Ryan,A.W., de
            Kovel,C., Holmes,G.K., Howdle,P.D., Walters,J.R., Sanders,D.S.,
            Mulder,C.J., Mearin,M.L., Verbeek,W.H., Trimble,V., Stevens,F.M.,
            Kelleher,D., Barisani,D., Bardella,M.T., McManus,R., van Heel,D.A.
            and Wijmenga,C.
  TITLE     Coeliac disease-associated risk variants in TNFAIP3 and REL
            implicate altered NF-kappaB signalling
  JOURNAL   Gut 58 (8), 1078-1083 (2009)
   PUBMED   19240061
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131935.7, AB078147.1 and BC037341.2.
            
            On Nov 23, 2018 this sequence version replaced NM_198516.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC060864.1, AK055111.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000227756.5/ ENSP00000227756.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-412               AC131935.7         159429-159840
            413-2236            AB078147.1         1-1824
            2237-2503           BC037341.2         2235-2501
FEATURES             Location/Qualifiers
     source          1..2503
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..2503
                     /gene="GALNT18"
                     /gene_synonym="GalNAc-T15; GalNAc-T18; GALNACT18; GALNT15;
                     GALNTL4"
                     /note="polypeptide N-acetylgalactosaminyltransferase 18"
                     /db_xref="GeneID:374378"
                     /db_xref="HGNC:HGNC:30488"
                     /db_xref="MIM:615136"
     exon            1..647
                     /gene="GALNT18"
                     /gene_synonym="GalNAc-T15; GalNAc-T18; GALNACT18; GALNT15;
                     GALNTL4"
                     /inference="alignment:Splign:2.1.0"
     CDS             413..2236
                     /gene="GALNT18"
                     /gene_synonym="GalNAc-T15; GalNAc-T18; GALNACT18; GALNT15;
                     GALNTL4"
                     /EC_number="2.4.1.41"
                     /note="isoform 1 is encoded by transcript variant 1;
                     putative polypeptide
                     N-acetylgalactosaminyltransferase-like protein 4;
                     UDP-N-acetyl-alpha-D-galactosamine:polypeptide
                     N-acetylgalactosaminyltransferase 15; GalNAc-transferase
                     18; galNAc-T-like protein 4; pp-GaNTase-like protein 4;
                     polypeptide GalNAc transferase-like protein 4; protein-UDP
                     acetylgalactosaminyltransferase-like protein 4;
                     UDP-GalNAc:polypeptide
                     N-acetylgalactosaminyltransferase-like protein 4;
                     UDP-N-acetyl-alpha-D-galactosamine:polypeptide
                     N-acetylgalactosaminyltransferase-like 4; polypeptide
                     GalNAc transferase 18;
                     UDP-N-acetyl-alpha-D-galactosamine:polypeptide
                     N-acetylgalactosaminyltransferase 18"
                     /codon_start=1
                     /product="polypeptide N-acetylgalactosaminyltransferase 18
                     isoform 1"
                     /protein_id="NP_940918.2"
                     /db_xref="CCDS:CCDS7807.1"
                     /db_xref="GeneID:374378"
                     /db_xref="HGNC:HGNC:30488"
                     /db_xref="MIM:615136"
                     /translation="MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQ
                     EPAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWG
                     QELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDSLPEVSIVF
                     IFVNEALSVLLRSIHSAMERTPPHLLKEIILVDDNSSNEELKEKLTEYVDKVNSQKPG
                     FIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRII
                     SPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCF
                     IVDRQYFQEIGLLDEGMEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTE
                     DLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTF
                     RWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCLDQGPDTENVPIMYICHGMTPQNVYY
                     TSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQGGPIQNR
                     KSKRCLELQENSDLEFGFQLVLQKCSGQHWSITNVLRSLAS"
     exon            648..840
                     /gene="GALNT18"
                     /gene_synonym="GalNAc-T15; GalNAc-T18; GALNACT18; GALNT15;
                     GALNTL4"
                     /inference="alignment:Splign:2.1.0"
     exon            841..1007
                     /gene="GALNT18"
                     /gene_synonym="GalNAc-T15; GalNAc-T18; GALNACT18; GALNT15;
                     GALNTL4"
                     /inference="alignment:Splign:2.1.0"
     exon            1008..1191
                     /gene="GALNT18"
                     /gene_synonym="GalNAc-T15; GalNAc-T18; GALNACT18; GALNT15;
                     GALNTL4"
                     /inference="alignment:Splign:2.1.0"
     exon            1192..1389
                     /gene="GALNT18"
                     /gene_synonym="GalNAc-T15; GalNAc-T18; GALNACT18; GALNT15;
                     GALNTL4"
                     /inference="alignment:Splign:2.1.0"
     exon            1390..1504
                     /gene="GALNT18"
                     /gene_synonym="GalNAc-T15; GalNAc-T18; GALNACT18; GALNT15;
                     GALNTL4"
                     /inference="alignment:Splign:2.1.0"
     exon            1505..1690
                     /gene="GALNT18"
                     /gene_synonym="GalNAc-T15; GalNAc-T18; GALNACT18; GALNT15;
                     GALNTL4"
                     /inference="alignment:Splign:2.1.0"
     exon            1691..1828
                     /gene="GALNT18"
                     /gene_synonym="GalNAc-T15; GalNAc-T18; GALNACT18; GALNT15;
                     GALNTL4"
                     /inference="alignment:Splign:2.1.0"
     exon            1829..1924
                     /gene="GALNT18"
                     /gene_synonym="GalNAc-T15; GalNAc-T18; GALNACT18; GALNT15;
                     GALNTL4"
                     /inference="alignment:Splign:2.1.0"
     exon            1925..2089
                     /gene="GALNT18"
                     /gene_synonym="GalNAc-T15; GalNAc-T18; GALNACT18; GALNT15;
                     GALNTL4"
                     /inference="alignment:Splign:2.1.0"
     exon            2090..2503
                     /gene="GALNT18"
                     /gene_synonym="GalNAc-T15; GalNAc-T18; GALNACT18; GALNT15;
                     GALNTL4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2483..2488
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GALNT18"
                     /gene_synonym="GalNAc-T15; GalNAc-T18; GALNACT18; GALNT15;
                     GALNTL4"
                     /note="hexamer: AATAAA"
     polyA_site      2503
                     /gene="GALNT18"
                     /gene_synonym="GalNAc-T15; GalNAc-T18; GALNACT18; GALNT15;
                     GALNTL4"
                     /note="major polyA site"
ORIGIN      
        1 gctgttctcc tagcagcgcg ggccggtcgg accgccaagg cagccggcgc tggcgatggg
       61 aagcggcgtg gccgccgaca caggcagtgg caaagtttcc cagacgtaca catctggacg
      121 cgcggctgcc ggctacccgt gacccctcta ggaagggttc agggattttt aatttggaaa
      181 aaaatccacc tggtttcctt tgtcaaggtc tctccgggtg gccagcggca ggagctgcaa
      241 acttgggcac ggcggctaca ccggcagcgg accgggcttt ggagaacctc gggactcagg
      301 tgctgaggtg cccagcggct ccggacgtgc tacggggtgc gagcgcgggg gagttcgggg
      361 cgcacgacaa ggaagggccc ccgggagctc tatatggagg aaggagccca gaatggtgtg
      421 caccaggaag accaaaactt tggtgtccac ttgcgtgatc ctgagcggca tgactaacat
      481 catctgcctg ctctacgtgg gctgggtcac caactacatc gccagcgtgt atgtgcgggg
      541 gcaggagccg gcgcccgaca agaagctgga ggaagacaaa ggggacactc tgaagattat
      601 tgagcggctg gaccacctgg agaatgtcat caagcagcac attcaagagg ctcctgccaa
      661 gcctgaggag gcagaggccg agcccttcac agactcctct ctgtttgcac actggggcca
      721 ggagctcagc cccgaaggcc ggcgcgtggc cctgaagcaa ttccagtact acggctacaa
      781 cgcctacctc agcgaccgcc tgcccctgga ccggcccctg cctgacctca gacccagtgg
      841 gtgccgtaac ctctcatttc ctgacagcct gccagaggtg agcatcgtgt tcatcttcgt
      901 caatgaagcg ctttcagtgc tgctgcgctc catccactcg gccatggaac gcacgccccc
      961 acatctgctc aaggagatca ttctggtgga tgacaacagc agtaacgagg aactgaagga
     1021 gaagctgacc gaatatgtgg acaaggtgaa cagccagaag ccaggcttca tcaaagtcgt
     1081 gcgtcacagc aagcaggaag gcctcatccg ctccagggtc agtggctgga gggcggccac
     1141 tgcccctgtg gtggcactct ttgatgccca cgtggagttc aatgtgggct gggctgaacc
     1201 tgtactcacc cgcatcaagg agaaccggaa gcggatcatc tcgccatcct ttgataacat
     1261 caaatatgac aactttgaga tagaagagta cccgctggct gcccagggct ttgactggga
     1321 gctgtggtgc cgctacctaa atccccccaa ggcctggtgg aagctggaga actccacagc
     1381 gccaatcagg agccctgccc tcattggctg cttcattgtg gaccggcagt acttccagga
     1441 gatcggcctg ctggacgaag gcatggaagt ctacgggggc gagaatgtgg agcttgggat
     1501 cagggtgtgg cagtgtggcg ggagtgtgga ggtcctgccc tgctcacgga ttgcccacat
     1561 tgagcgagcc cacaagccct acacagagga cctcaccgcc catgtccgca ggaacgctct
     1621 cagggtggct gaagtctgga tggatgaatt taaaagccac gtctacatgg catggaacat
     1681 accgcaggag gactcaggaa ttgacattgg ggacatcact gcaaggaagg ctctcaggaa
     1741 acagctgcag tgcaagacct tccggtggta cctggtcagc gtgtacccag agatgaggat
     1801 gtactccgac atcattgcct atggagtgct gcagaattct ctgaagactg atttgtgtct
     1861 tgaccagggg ccagatacag agaatgtccc catcatgtac atctgccatg ggatgacgcc
     1921 tcagaacgtg tactacacga gcagtcagca gatccatgtg ggcattctga gccccaccgt
     1981 ggatgatgat gacaaccgat gcctggtgga cgtcaacagc cggccccggc tcatcgaatg
     2041 cagctacgcc aaagccaaga ggatgaagct tcactggcag ttctctcagg gaggacccat
     2101 ccagaaccgc aagtctaagc gctgtctgga gctgcaggag aatagcgacc tggagttcgg
     2161 cttccagctg gtgttgcaga agtgctcggg ccagcactgg agcatcacca acgtcctgag
     2221 gagcctcgcg tcctgaccca ccggggccac ttccggctgc ctctttgcta ctgtgtagca
     2281 cctgctgcaa cgttgcctgc tgtccacgtg gggttgtttg gagtctgggg aaccaggtta
     2341 gtgggccccc aagaagagct ttttatttcc tattcaattt tcatggagtt tatagaaaga
     2401 tgctgattgg taggtgatgg tatgatatca aactattttg cagttgtaaa taggggacag
     2461 atggaaaata tttataactg acaataaaat attattaaga aaa
//
