LOCUS       XM_017023113            5112 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens galactosamine (N-acetyl)-6-sulfatase
            (GALNS), transcript variant X6, mRNA.
ACCESSION   XM_017023113
VERSION     XM_017023113.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000016.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017023113.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5112
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
     gene            1..5112
                     /gene="GALNS"
                     /gene_synonym="GalN6S; GALNAC6S; GAS; MPS4A"
                     /note="galactosamine (N-acetyl)-6-sulfatase; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 20 ESTs, 461 long SRA reads, and 94% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     62 samples with support for all annotated introns"
                     /db_xref="GeneID:2588"
                     /db_xref="HGNC:HGNC:4122"
                     /db_xref="MIM:612222"
     CDS             502..1674
                     /gene="GALNS"
                     /gene_synonym="GalN6S; GALNAC6S; GAS; MPS4A"
                     /codon_start=1
                     /product="N-acetylgalactosamine-6-sulfatase isoform X6"
                     /protein_id="XP_016878602.1"
                     /db_xref="GeneID:2588"
                     /db_xref="HGNC:HGNC:4122"
                     /db_xref="MIM:612222"
                     /translation="MVGRYYEEFPINLKTGEANLTQIYLQEALDFIKRQARHHPFFLY
                     WAVDATHAPVYASKPFLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFVFFTS
                     DNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIMDL
                     FTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDRPIFYYRGDTLMAATLGQHKAHFW
                     TWTNSWENFRQGIDFCPGQNVSGVTTHNLEDHTKLPLIFHLGRDPGERFPLSFASAEY
                     QEALSRITSVVQQHQEALVPAQPQLNVCNWAVMAPTQSSTSVQPDKTRPCSPPVEKRP
                     HHASIGQKHKHRRASKVSLKSVFRPQRMRRRLVQPWGPQQSGPLRSSFSVPCLGVP"
     polyA_site      5112
                     /gene="GALNS"
                     /gene_synonym="GalN6S; GALNAC6S; GAS; MPS4A"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agccggaagg gccggcggac gctcgctagg tcggctcgct ggccggggct ccgcggctcc
       61 cgtggttgcc atggcggcgg ttgtcgcggc gacgaggtgg tggcagctgt tgctggtgct
      121 cagcgccgcg gggatggggg cctcgggcgc cccgcagccc cccaacatcc tgctcctgct
      181 catggacgac cgagggcggc actgctcaca ggacggctac ccatccgcaa tggcttctac
      241 accaccaacg cccatgccag aaacgcctac acaccgcagg agattgtggg cggcatccca
      301 gactcggagc agctcctgcc ggagcttctg aagaaggccg gctacgtcag caagattgtc
      361 ggcaagtggc atctgggtca caggccccag ttccaccccc tgaagcacgg atttgatgag
      421 tggtttggat cccccaactg ccactttgga ccttatgaca acaaggccag gcccaacatc
      481 cctgtgtaca gggactggga gatggttggc agatattatg aagaatttcc tattaatctg
      541 aagacggggg aagccaacct cacccagatc tacctgcagg aagccctgga cttcattaag
      601 agacaggcac ggcaccaccc ctttttcctc tactgggctg tcgacgccac gcacgcaccc
      661 gtctatgcct ccaaaccctt cttgggcacc agtcagcgag ggcggtatgg agacgccgtc
      721 cgggagattg atgacagcat tgggaagata ctggagctcc tccaagacct gcacgtcgcg
      781 gacaacacct tcgtcttctt cacgtcggac aacggcgctg ccctcatttc cgcccccgaa
      841 caaggtggca gcaacggccc ctttctgtgt gggaagcaga ccacgtttga aggagggatg
      901 agggagcctg ccctcgcatg gtggccaggg cacgtcactg caggccaggt gagccaccag
      961 ctgggcagca tcatggacct cttcaccacc agcctggccc ttgcgggcct gacgccgccc
     1021 agcgacaggg ccattgatgg cctcaacctc ctccccaccc tcctgcaggg ccggctgatg
     1081 gacaggccta tcttctatta ccgtggcgac acgctgatgg cggccaccct cgggcagcac
     1141 aaggctcact tctggacctg gaccaactcc tgggagaact tcagacaggg cattgatttc
     1201 tgccctgggc agaacgtttc aggggtcaca actcacaatc tggaagacca cacgaagctg
     1261 cccctgatct tccacctggg acgggaccca ggggagaggt tccccctcag ctttgccagc
     1321 gccgagtacc aggaggccct cagcaggatc acctcggtcg tccagcagca ccaggaggcc
     1381 ttggtccccg cgcagcccca gctcaacgtg tgcaactggg cggtcatggc acccacccag
     1441 agcagcacct ccgtgcagcc tgacaagacc aggccttgtt cacctccagt agagaaacgg
     1501 cctcatcacg ccagcatcgg ccagaaacac aagcacagac gtgcctccaa agtttcactg
     1561 aagtctgtgt tcaggccaca aaggatgcgt cgtcgtcttg tccagccctg ggggccgcag
     1621 cagtcagggc ctctcaggag cagcttttct gtcccctgct tgggggtccc atagggtggc
     1681 atgtggacgg cccagccatc ccgcgtgtgc agtggccgca aaggcctgtt tcccagcaca
     1741 gctgatgtgg gtcccagcag ggcaggtctt cacagctcct tcagatggga cacgtgcggc
     1801 cctcgctcta gtcggcaaaa acgagccaca cacaggtctg cggtgtcgct cctgggtgcc
     1861 cagagcccac cgagcacagt ggagatggcc gagcccagcc tcgaggcccc tgggccgtcg
     1921 ctcacctgtt tacacgggct gggcgtggct gcccacagcc cctggatctg ccgcgcagga
     1981 ttcgggaaga aggcccctcg gcagctgcag acttcagcct gggctcctgc tgtgcgggcg
     2041 aaaaggccca gctgaagcct ctttccaggg ccagacccgg ctgcagcgtg ggagccgctg
     2101 ggtgcccgcc gtgccgtggg aaggaaggtg gtggctctga acagccaggg agccacagcg
     2161 tgggccggcg gatgtaacag gagagcaccg gccatcggga gcacctacca gcagtgagga
     2221 ccatggaggg cagatggcct tgtccctgcc cagggacagt ccaccctgca gggttattta
     2281 ggactgggca gggcagggcc acctccgtta gttggggggc ggggggcggg ggtgcctggc
     2341 aagtttcata ggaagatatt cagggccctt ccttcaaagg gacctgggca gctggcgtcc
     2401 ccgcctctgg actcagtggt ggagcaggga ggtccctgtc tcaggacccc tgagtctcgg
     2461 ggccccagga gcccagggcc accagccgtg gaggagccct ggccttctgc cttccacacc
     2521 caatcccact ccgtgctgct gggtccttct ctacgaccca ggctgcagtg gctccacggg
     2581 cgcaggccac acctgccatg gagacagtgg gcacagggca ggggaggtgg gcgcacacag
     2641 cctggctgcc actgccatct cctgggcact gggggaactg cccccaccgc cacacctgtg
     2701 ctctctgcag ggggaaaagt gccaactcag acctggcgag ctgagccact ggggtctgag
     2761 gggcccagat gccaccgtga gcagagccat gggggagatg cacagacacg cgtgtgaagc
     2821 ctgggggccc tccttacccc ttccctgccc tctgtccccg ccaactccag gccagcccca
     2881 ggagaggggc tcagtggcgt ctctggcaca gaggagaggg agtgtggcca cctggacccc
     2941 tgcttctggg acagctgagc ggcctttgag aaatgcagat cccccatcca gactcaaaca
     3001 caccctgcgg ctgcctctgc tgcccctgga gtttgggagc agcttcctca cccaaaccca
     3061 ctcctgctct ggtggccaag ggggcaggga cactcatgcg gcatccctgc tgccgcctag
     3121 ggctggagac tgtccttagt accctgagca gcacccagaa tccaaagtct gtccccggaa
     3181 agtgccctca gggccatgcg gcgtctgacg tggcacagaa gtggcctgga tggggacaca
     3241 gaaccaaact gcactcattt cagccaagaa ggctcctctt agcggcataa gtctcccttt
     3301 ctgttgccag gaaaagtgcc ctcccatcaa gcaaggcttc cgctaagcaa ggctgcactg
     3361 tgaggtccac acacacccag gcgatggagg ggtgcgggct ccgctcagca ccgcactgaa
     3421 ctgagcccag cagcgcagta gggactggct tctccctggg aaaggcttct tgagaggctg
     3481 aagctgcagg agagggtgat gagttgagaa gctcagggtg ggccctcctg ggaggaccgc
     3541 ctgccctttc taacactgct ggccctcgga ggccctcagc cacttggcag ctgcatcccc
     3601 catacccggg acctccccac caagttctca tttctccaat ggcagccttc agagctgaga
     3661 ggccgagtca agagggtgcc atctcccaag ttcccatgat tcctggggag cgtctgtgta
     3721 gctgcccacc tggaccgagg tggtccccac actgaggcca attggttggg gtccggggtt
     3781 gacctgggca ggggacacat caaaactgct cgaggccaag cgcggtggct cacgcctata
     3841 atcccagcac tttgggaggc caaggcaggt ggatcacctg aggtcagaag tttgagacca
     3901 gcctggccaa cttggggaac ccttgtctct accaaaaata caaaaatggt tgggcgtggt
     3961 ggctcacacc tgtaatccca gcaccttggg aggccaaggc aggtggatca cgaggtcagg
     4021 agttcaagac cagcctggtc aagatggtga aactccgtct ctactaaaaa tacaaaaatt
     4081 agccaggcgt ggtggcgcgt gcctgtaatc ccagcagcta ctcactcagg aggctgaggc
     4141 aggagaatct cttgaacccg gaaggcagag gttgcagtga gccaagatcg cgccactgaa
     4201 ctccagcctg ggtgacagag tgagactgtc tcagaacagc aacaacaaaa tgcccgctgc
     4261 tgctgggtcc agaagagctt gaataactgc atgttctttt tctcaatttt catttcccag
     4321 aactgggcac ctccgggctg tgaaaagtta gggaagtgtc tgacacctcc agaatccatt
     4381 cccaagaagt gcctctggtc ccactagcac ctgcgcagac tcaggccagg cctagaatct
     4441 ccggttggcc ctgcaagtgc ctggaggaag gatggctctg gcctcggtcc tcccccaacc
     4501 ctgcccaagc cagacagaca gcacctgcag acgcaggggg actgcacaat tccacctgcc
     4561 caggacctga ccctggcgtg tgcttggccc tcctcctcgc ccacggcgcc tcagatttca
     4621 ggaccctcct cctcgcccac ggcgcctcag acctcaggac cctgccgtct cacgcctttg
     4681 tgaaccccaa atatctgaga ccagtctcag tttattttgc caaggttaag gatgcacctg
     4741 tgacagcctc aggaggtcct gacaacaggt gcctgaggtg gctggggata cagtttgcct
     4801 ttatacatct tagggagaca caagatcagt atgtgtatgg cgtacattgg ttcagtcagc
     4861 cttccactga atacacgatt gagtctggcc cagtgaatcc gcatttttat gtaaacagta
     4921 agggaacggg gcaatcatat aagcgtttgt ctcaggggag ccccagaggg atgacttcca
     4981 gttccgtctg tcctttgtcc acaaggaatt tccctggacg ctaattatga gggaggcgtg
     5041 tagcttctta tcattgtaac tatgttattt agaaataaaa cgggaggcag gtttgcctaa
     5101 ttcccagctt ga
//
