LOCUS       XM_011522982            5406 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens galactosamine (N-acetyl)-6-sulfatase
            (GALNS), transcript variant X1, mRNA.
ACCESSION   XM_011522982
VERSION     XM_011522982.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000016.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011522982.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 5% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5406
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
     gene            1..5406
                     /gene="GALNS"
                     /gene_synonym="GalN6S; GALNAC6S; GAS; MPS4A"
                     /note="galactosamine (N-acetyl)-6-sulfatase; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 20 ESTs, 422 long SRA reads, and 93% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     25 samples with support for all annotated introns"
                     /db_xref="GeneID:2588"
                     /db_xref="HGNC:HGNC:4122"
                     /db_xref="MIM:612222"
     CDS             223..1968
                     /gene="GALNS"
                     /gene_synonym="GalN6S; GALNAC6S; GAS; MPS4A"
                     /codon_start=1
                     /product="N-acetylgalactosamine-6-sulfatase isoform X1"
                     /protein_id="XP_011521284.1"
                     /db_xref="GeneID:2588"
                     /db_xref="HGNC:HGNC:4122"
                     /db_xref="MIM:612222"
                     /translation="MQMLVSGWEEADGHIPHLKTKQKWRRKTAWADRGAAPSCTHAGD
                     AEMGWGDLGVYGEPSRETPNLDRMAAEGLLFPNFYSANPLCSPSRAALLTGRLPIRNG
                     FYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAGYVSKIVGKWHLGHRPQFHPLKH
                     GFDEWFGSPNCHFGPYDNKARPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQIYLQE
                     ALDFIKRQARHHPFFLYWAVDATHAPVYASKPFLGTSQRGRYGDAVREIDDSIGKILE
                     LLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPG
                     HVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDRPIFYYR
                     GDTLMAATLGQHKAHFWTWTNSWENFRQGIDFCPGQNVSGVTTHNLEDHTKLPLIFHL
                     GRDPGERFPLSFASAEYQEALSRITSVVQQHQEALVPAQPQLNVCNWAVMAPTQSSTS
                     VQPDKTRPCSPPVEKRPHHASIGQKHKHRRASKVSLKSVFRPQRMRRRLVQPWGPQQS
                     GPLRSSFSVPCLGVP"
     polyA_site      5406
                     /gene="GALNS"
                     /gene_synonym="GalN6S; GALNAC6S; GAS; MPS4A"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agccggaagg gccggcggac gctcgctagg tcggctcgct ggccggggct ccgcggctcc
       61 cgtggttgcc atggcggcgg ttgtcgcggc gacgaggtgg tggcagctgt tgctggtgct
      121 cagcgccgcg gggatggggg cctcgggcgc cccgcagccc cccaacatcc tgctcctgct
      181 catggacgac atgcacgtgt ttagaggcca gctcctgcga gcatgcagat gctggtgtca
      241 ggctgggagg aggcagacgg acacattccc cacctgaaga ccaagcagaa gtggaggcga
      301 aagacagcgt gggctgaccg tggagcggcc ccatcgtgca cgcacgcagg cgatgctgag
      361 atgggatggg gtgacctcgg ggtgtatgga gagccctcca gagagacccc gaatttggac
      421 cggatggctg cagaagggct gcttttccca aacttctatt ctgccaaccc tctgtgctcg
      481 ccatcgaggg cggcactgct cacaggacgg ctacccatcc gcaatggctt ctacaccacc
      541 aacgcccatg ccagaaacgc ctacacaccg caggagattg tgggcggcat cccagactcg
      601 gagcagctcc tgccggagct tctgaagaag gccggctacg tcagcaagat tgtcggcaag
      661 tggcatctgg gtcacaggcc ccagttccac cccctgaagc acggatttga tgagtggttt
      721 ggatccccca actgccactt tggaccttat gacaacaagg ccaggcccaa catccctgtg
      781 tacagggact gggagatggt tggcagatat tatgaagaat ttcctattaa tctgaagacg
      841 ggggaagcca acctcaccca gatctacctg caggaagccc tggacttcat taagagacag
      901 gcacggcacc accccttttt cctctactgg gctgtcgacg ccacgcacgc acccgtctat
      961 gcctccaaac ccttcttggg caccagtcag cgagggcggt atggagacgc cgtccgggag
     1021 attgatgaca gcattgggaa gatactggag ctcctccaag acctgcacgt cgcggacaac
     1081 accttcgtct tcttcacgtc ggacaacggc gctgccctca tttccgcccc cgaacaaggt
     1141 ggcagcaacg gcccctttct gtgtgggaag cagaccacgt ttgaaggagg gatgagggag
     1201 cctgccctcg catggtggcc agggcacgtc actgcaggcc aggtgagcca ccagctgggc
     1261 agcatcatgg acctcttcac caccagcctg gcccttgcgg gcctgacgcc gcccagcgac
     1321 agggccattg atggcctcaa cctcctcccc accctcctgc agggccggct gatggacagg
     1381 cctatcttct attaccgtgg cgacacgctg atggcggcca ccctcgggca gcacaaggct
     1441 cacttctgga cctggaccaa ctcctgggag aacttcagac agggcattga tttctgccct
     1501 gggcagaacg tttcaggggt cacaactcac aatctggaag accacacgaa gctgcccctg
     1561 atcttccacc tgggacggga cccaggggag aggttccccc tcagctttgc cagcgccgag
     1621 taccaggagg ccctcagcag gatcacctcg gtcgtccagc agcaccagga ggccttggtc
     1681 cccgcgcagc cccagctcaa cgtgtgcaac tgggcggtca tggcacccac ccagagcagc
     1741 acctccgtgc agcctgacaa gaccaggcct tgttcacctc cagtagagaa acggcctcat
     1801 cacgccagca tcggccagaa acacaagcac agacgtgcct ccaaagtttc actgaagtct
     1861 gtgttcaggc cacaaaggat gcgtcgtcgt cttgtccagc cctgggggcc gcagcagtca
     1921 gggcctctca ggagcagctt ttctgtcccc tgcttggggg tcccataggg tggcatgtgg
     1981 acggcccagc catcccgcgt gtgcagtggc cgcaaaggcc tgtttcccag cacagctgat
     2041 gtgggtccca gcagggcagg tcttcacagc tccttcagat gggacacgtg cggccctcgc
     2101 tctagtcggc aaaaacgagc cacacacagg tctgcggtgt cgctcctggg tgcccagagc
     2161 ccaccgagca cagtggagat ggccgagccc agcctcgagg cccctgggcc gtcgctcacc
     2221 tgtttacacg ggctgggcgt ggctgcccac agcccctgga tctgccgcgc aggattcggg
     2281 aagaaggccc ctcggcagct gcagacttca gcctgggctc ctgctgtgcg ggcgaaaagg
     2341 cccagctgaa gcctctttcc agggccagac ccggctgcag cgtgggagcc gctgggtgcc
     2401 cgccgtgccg tgggaaggaa ggtggtggct ctgaacagcc agggagccac agcgtgggcc
     2461 ggcggatgta acaggagagc accggccatc gggagcacct accagcagtg aggaccatgg
     2521 agggcagatg gccttgtccc tgcccaggga cagtccaccc tgcagggtta tttaggactg
     2581 ggcagggcag ggccacctcc gttagttggg gggcgggggg cgggggtgcc tggcaagttt
     2641 cataggaaga tattcagggc ccttccttca aagggacctg ggcagctggc gtccccgcct
     2701 ctggactcag tggtggagca gggaggtccc tgtctcagga cccctgagtc tcggggcccc
     2761 aggagcccag ggccaccagc cgtggaggag ccctggcctt ctgccttcca cacccaatcc
     2821 cactccgtgc tgctgggtcc ttctctacga cccaggctgc agtggctcca cgggcgcagg
     2881 ccacacctgc catggagaca gtgggcacag ggcaggggag gtgggcgcac acagcctggc
     2941 tgccactgcc atctcctggg cactggggga actgccccca ccgccacacc tgtgctctct
     3001 gcagggggaa aagtgccaac tcagacctgg cgagctgagc cactggggtc tgaggggccc
     3061 agatgccacc gtgagcagag ccatggggga gatgcacaga cacgcgtgtg aagcctgggg
     3121 gccctcctta ccccttccct gccctctgtc cccgccaact ccaggccagc cccaggagag
     3181 gggctcagtg gcgtctctgg cacagaggag agggagtgtg gccacctgga cccctgcttc
     3241 tgggacagct gagcggcctt tgagaaatgc agatccccca tccagactca aacacaccct
     3301 gcggctgcct ctgctgcccc tggagtttgg gagcagcttc ctcacccaaa cccactcctg
     3361 ctctggtggc caagggggca gggacactca tgcggcatcc ctgctgccgc ctagggctgg
     3421 agactgtcct tagtaccctg agcagcaccc agaatccaaa gtctgtcccc ggaaagtgcc
     3481 ctcagggcca tgcggcgtct gacgtggcac agaagtggcc tggatgggga cacagaacca
     3541 aactgcactc atttcagcca agaaggctcc tcttagcggc ataagtctcc ctttctgttg
     3601 ccaggaaaag tgccctccca tcaagcaagg cttccgctaa gcaaggctgc actgtgaggt
     3661 ccacacacac ccaggcgatg gaggggtgcg ggctccgctc agcaccgcac tgaactgagc
     3721 ccagcagcgc agtagggact ggcttctccc tgggaaaggc ttcttgagag gctgaagctg
     3781 caggagaggg tgatgagttg agaagctcag ggtgggccct cctgggagga ccgcctgccc
     3841 tttctaacac tgctggccct cggaggccct cagccacttg gcagctgcat cccccatacc
     3901 cgggacctcc ccaccaagtt ctcatttctc caatggcagc cttcagagct gagaggccga
     3961 gtcaagaggg tgccatctcc caagttccca tgattcctgg ggagcgtctg tgtagctgcc
     4021 cacctggacc gaggtggtcc ccacactgag gccaattggt tggggtccgg ggttgacctg
     4081 ggcaggggac acatcaaaac tgctcgaggc caagcgcggt ggctcacgcc tataatccca
     4141 gcactttggg aggccaaggc aggtggatca cctgaggtca gaagtttgag accagcctgg
     4201 ccaacttggg gaacccttgt ctctaccaaa aatacaaaaa tggttgggcg tggtggctca
     4261 cacctgtaat cccagcacct tgggaggcca aggcaggtgg atcacgaggt caggagttca
     4321 agaccagcct ggtcaagatg gtgaaactcc gtctctacta aaaatacaaa aattagccag
     4381 gcgtggtggc gcgtgcctgt aatcccagca gctactcact caggaggctg aggcaggaga
     4441 atctcttgaa cccggaaggc agaggttgca gtgagccaag atcgcgccac tgaactccag
     4501 cctgggtgac agagtgagac tgtctcagaa cagcaacaac aaaatgcccg ctgctgctgg
     4561 gtccagaaga gcttgaataa ctgcatgttc tttttctcaa ttttcatttc ccagaactgg
     4621 gcacctccgg gctgtgaaaa gttagggaag tgtctgacac ctccagaatc cattcccaag
     4681 aagtgcctct ggtcccacta gcacctgcgc agactcaggc caggcctaga atctccggtt
     4741 ggccctgcaa gtgcctggag gaaggatggc tctggcctcg gtcctccccc aaccctgccc
     4801 aagccagaca gacagcacct gcagacgcag ggggactgca caattccacc tgcccaggac
     4861 ctgaccctgg cgtgtgcttg gccctcctcc tcgcccacgg cgcctcagat ttcaggaccc
     4921 tcctcctcgc ccacggcgcc tcagacctca ggaccctgcc gtctcacgcc tttgtgaacc
     4981 ccaaatatct gagaccagtc tcagtttatt ttgccaaggt taaggatgca cctgtgacag
     5041 cctcaggagg tcctgacaac aggtgcctga ggtggctggg gatacagttt gcctttatac
     5101 atcttaggga gacacaagat cagtatgtgt atggcgtaca ttggttcagt cagccttcca
     5161 ctgaatacac gattgagtct ggcccagtga atccgcattt ttatgtaaac agtaagggaa
     5221 cggggcaatc atataagcgt ttgtctcagg ggagccccag agggatgact tccagttccg
     5281 tctgtccttt gtccacaagg aatttccctg gacgctaatt atgagggagg cgtgtagctt
     5341 cttatcattg taactatgtt atttagaaat aaaacgggag gcaggtttgc ctaattccca
     5401 gcttga
//
