LOCUS       NM_001098405             561 bp    mRNA    linear   PRI 12-JUN-2024
DEFINITION  Homo sapiens G antigen 12F (GAGE12F), mRNA.
ACCESSION   NM_001098405
VERSION     NM_001098405.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 561)
  AUTHORS   Shi,D.B., Ma,R.R., Zhang,H., Hou,F., Guo,X.Y. and Gao,P.
  TITLE     GAGE7B promotes tumor metastasis and growth via activating the
            p38delta/pMAPKAPK2/pHSP27 pathway in gastric cancer
  JOURNAL   J Exp Clin Cancer Res 38 (1), 124 (2019)
   PUBMED   30871606
  REMARK    GeneRIF: GAGE7B significantly promotes gastric cancer progression
            by upregulating the p38delta/pMAPKAPK2/pHSP27 pathway, but it is
            negatively regulated by miR-30c.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 561)
  AUTHORS   Gjerstorff,M.F. and Ditzel,H.J.
  TITLE     An overview of the GAGE cancer/testis antigen family with the
            inclusion of newly identified members
  JOURNAL   Tissue Antigens 71 (3), 187-192 (2008)
   PUBMED   18179644
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC142497.3.
            
            On Jan 12, 2021 this sequence version replaced NM_001098405.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: HY010893.1, BI868671.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000440137.2/ ENSP00000404123.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-108               AC142497.3         32448-32555
            109-200             AC142497.3         33595-33686
            201-321             AC142497.3         34152-34272
            322-447             AC142497.3         37101-37226
            448-561             AC142497.3         39698-39811
FEATURES             Location/Qualifiers
     source          1..561
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xp11.23"
     gene            1..561
                     /gene="GAGE12F"
                     /gene_synonym="AL4; CT4.7; GAGE-7; GAGE-7B; GAGE-8; GAGE7;
                     GAGE7B"
                     /note="G antigen 12F"
                     /db_xref="GeneID:100008586"
                     /db_xref="HGNC:HGNC:31906"
                     /db_xref="MIM:300730"
     exon            1..108
                     /gene="GAGE12F"
                     /gene_synonym="AL4; CT4.7; GAGE-7; GAGE-7B; GAGE-8; GAGE7;
                     GAGE7B"
                     /inference="alignment:Splign:2.1.0"
     exon            109..200
                     /gene="GAGE12F"
                     /gene_synonym="AL4; CT4.7; GAGE-7; GAGE-7B; GAGE-8; GAGE7;
                     GAGE7B"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..470
                     /gene="GAGE12F"
                     /gene_synonym="AL4; CT4.7; GAGE-7; GAGE-7B; GAGE-8; GAGE7;
                     GAGE7B"
                     /note="g antigen 12F/G/I; GAGE-12F; G antigen 7; G antigen
                     12G; G antigen 12I; Cancer/testis antigen 4.7"
                     /codon_start=1
                     /product="G antigen 12F"
                     /protein_id="NP_001091875.1"
                     /db_xref="CCDS:CCDS43946.1"
                     /db_xref="GeneID:100008586"
                     /db_xref="HGNC:HGNC:31906"
                     /db_xref="MIM:300730"
                     /translation="MSWRGRSTYYWPRPRRYVQPPEMIGPMRPEQFSDEVEPATPEEG
                     EPATQRQDPAAAQEGEDEGASAGQGPKPEAHSQEQGHPQTGCECEDGPDGQEMDPPNP
                     EEVKTPEEGEKQSQC"
     exon            201..321
                     /gene="GAGE12F"
                     /gene_synonym="AL4; CT4.7; GAGE-7; GAGE-7B; GAGE-8; GAGE7;
                     GAGE7B"
                     /inference="alignment:Splign:2.1.0"
     exon            322..447
                     /gene="GAGE12F"
                     /gene_synonym="AL4; CT4.7; GAGE-7; GAGE-7B; GAGE-8; GAGE7;
                     GAGE7B"
                     /inference="alignment:Splign:2.1.0"
     exon            448..561
                     /gene="GAGE12F"
                     /gene_synonym="AL4; CT4.7; GAGE-7; GAGE-7B; GAGE-8; GAGE7;
                     GAGE7B"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcttctgcc cggccccttc gcccacgtga agaacgccag ggagctgtga ggcagtgctg
       61 tgtggttcct gccgtccgga ctctttttcc tctactgaga ttcatctgtg tgaaatatga
      121 gttggcgagg aagatcgacc tattattggc ctagaccaag gcgctatgta cagcctcctg
      181 aaatgattgg gcctatgcgg cccgagcagt tcagtgatga agtggaacca gcaacacctg
      241 aagaagggga accagcaact caacgtcagg atcctgcagc tgctcaggag ggagaggatg
      301 agggagcatc tgcaggtcaa gggccgaagc ctgaagctca tagccaggaa cagggtcacc
      361 cacagactgg gtgtgagtgt gaagatggtc ctgatgggca ggagatggac ccgccaaatc
      421 cagaggaggt gaaaacgcct gaagaaggtg aaaagcaatc acagtgttaa aagaagacac
      481 gttgaaatga tgcaggctgc tcctatgttg gaaatttgtt cattaaaatt ctcccaataa
      541 agctttacag ccttctgcaa a
//
