LOCUS       NM_001127345             545 bp    mRNA    linear   PRI 17-FEB-2024
DEFINITION  Homo sapiens G antigen 12B (GAGE12B), mRNA.
ACCESSION   NM_001127345
VERSION     NM_001127345.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 545)
  AUTHORS   Nin,D.S., Wujanto,C., Tan,T.Z., Lim,D., Damen,J.M.A., Wu,K.Y.,
            Dai,Z.M., Lee,Z.W., Idres,S.B., Leong,Y.H., Jha,S., Ng,J.S.,
            Low,J.J.H., Chang,S.C., Tan,D.S.P., Wu,W., Choo,B.A. and Deng,L.W.
  TITLE     GAGE mediates radio resistance in cervical cancers via the
            regulation of chromatin accessibility
  JOURNAL   Cell Rep 36 (9), 109621 (2021)
   PUBMED   34469741
  REMARK    GeneRIF: GAGE mediates radio resistance in cervical cancers via the
            regulation of chromatin accessibility.
REFERENCE   2  (bases 1 to 545)
  AUTHORS   Gjerstorff,M.F. and Ditzel,H.J.
  TITLE     An overview of the GAGE cancer/testis antigen family with the
            inclusion of newly identified members
  JOURNAL   Tissue Antigens 71 (3), 187-192 (2008)
   PUBMED   18179644
  REMARK    Review article
REFERENCE   3  (bases 1 to 545)
  AUTHORS   Harrington,J.J., Sherf,B., Rundlett,S., Jackson,P.D., Perry,R.,
            Cain,S., Leventhal,C., Thornton,M., Ramachandran,R.,
            Whittington,J., Lerner,L., Costanzo,D., McElligott,K., Boozer,S.,
            Mays,R., Smith,E., Veloso,N., Klika,A., Hess,J., Cothren,K., Lo,K.,
            Offenbacher,J., Danzig,J. and Ducar,M.
  TITLE     Creation of genome-wide protein expression libraries using random
            activation of gene expression
  JOURNAL   Nat Biotechnol 19 (5), 440-445 (2001)
   PUBMED   11329013
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC233302.2 and AC142497.3.
            
            On Dec 28, 2020 this sequence version replaced NM_001127345.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BM832793.1, HY012971.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-92                AC233302.2         7140-7231           c
            93-184              AC233302.2         6008-6099           c
            185-305             AC233302.2         5422-5542           c
            306-431             AC233302.2         2473-2598           c
            432-545             AC142497.3         1475-1588
FEATURES             Location/Qualifiers
     source          1..545
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xp11.23"
     gene            1..545
                     /gene="GAGE12B"
                     /gene_synonym="GAGE-12B"
                     /note="G antigen 12B"
                     /db_xref="GeneID:729428"
                     /db_xref="HGNC:HGNC:26779"
     exon            1..92
                     /gene="GAGE12B"
                     /gene_synonym="GAGE-12B"
                     /inference="alignment:Splign:2.1.0"
     exon            93..184
                     /gene="GAGE12B"
                     /gene_synonym="GAGE-12B"
                     /inference="alignment:Splign:2.1.0"
     CDS             101..454
                     /gene="GAGE12B"
                     /gene_synonym="GAGE-12B"
                     /codon_start=1
                     /product="G antigen 12B/C/D/E"
                     /protein_id="NP_001120817.2"
                     /db_xref="GeneID:729428"
                     /db_xref="HGNC:HGNC:26779"
                     /translation="MSWRGRSTYYWPRPRRYVQPPEMIGPMRPEQFSDEVEPATPEEG
                     EPATQRQDPAAAQEGEDEGASAGQGPKPEAHSQEQGHPQTGCECEDGPDGQEMDPPNP
                     EEVKTPEEGEKQSQC"
     exon            185..305
                     /gene="GAGE12B"
                     /gene_synonym="GAGE-12B"
                     /inference="alignment:Splign:2.1.0"
     exon            306..431
                     /gene="GAGE12B"
                     /gene_synonym="GAGE-12B"
                     /inference="alignment:Splign:2.1.0"
     exon            432..545
                     /gene="GAGE12B"
                     /gene_synonym="GAGE-12B"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttcgcccac gtgaagaacg ccagggagct gtgaggcagt gctgtgtggt tcctgccgtc
       61 cggactcttt ttcctctact gagattcatc tgtgtgaaat atgagttggc gaggaagatc
      121 gacctattat tggcctagac caaggcgcta tgtacagcct cctgaaatga ttgggcctat
      181 gcggcccgag cagttcagtg atgaagtgga accagcaaca cctgaagaag gggaaccagc
      241 aactcaacgt caggatcctg cagctgctca ggagggagag gatgagggag catctgcagg
      301 tcaagggccg aagcctgaag ctcatagcca ggaacagggt cacccacaga ctgggtgtga
      361 gtgtgaagat ggtcctgatg ggcaggagat ggacccgcca aatccagagg aggtgaaaac
      421 gcctgaagaa ggtgaaaagc aatcacagtg ttaaaagaag acacgttgaa atgatgcagg
      481 ctgctcctat gttggaaatt tgttcattaa aattctccca ataaagcttt acagccttct
      541 gcaaa
//
