LOCUS       NM_033223              10862 bp    mRNA    linear   PRI 01-AUG-2024
DEFINITION  Homo sapiens gamma-aminobutyric acid type A receptor subunit gamma3
            (GABRG3), transcript variant 1, mRNA.
ACCESSION   NM_033223
VERSION     NM_033223.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 10862)
  AUTHORS   Coskunpinar,E.M., Tur,S., Cevher Binici,N. and Yazan Songur,C.
  TITLE     Association of GABRG3, GABRB3, HTR2A gene variants with autism
            spectrum disorder
  JOURNAL   Gene 870, 147399 (2023)
   PUBMED   37019319
  REMARK    GeneRIF: Association of GABRG3, GABRB3, HTR2A gene variants with
            autism spectrum disorder.
REFERENCE   2  (bases 1 to 10862)
  AUTHORS   Ali,Z.A., Yasseen,A.A., McAllister,K.A., Al-Dujailli,A.,
            Al-Karaqully,A.J. and Jumaah,A.S.
  TITLE     SNP-PCR genotyping links alterations in the GABAA receptor (GABRG3:
            rs208129) and RELN (rs73670) genes to autism spectrum disorder
            among peadiatric Iraqi Arabs
  JOURNAL   Mol Biol Rep 49 (7), 6019-6028 (2022)
   PUBMED   35403940
  REMARK    GeneRIF: SNP-PCR genotyping links alterations in the GABAA receptor
            (GABRG3: rs208129) and RELN (rs73670) genes to autism spectrum
            disorder among peadiatric Iraqi Arabs.
REFERENCE   3  (bases 1 to 10862)
  AUTHORS   Saha,S., Chatterjee,M., Dutta,N., Sinha,S. and Mukhopadhyay,K.
  TITLE     GABA Receptor SNPs and Elevated Plasma GABA Levels Affect the
            Severity of the Indian ASD Probands
  JOURNAL   J Mol Neurosci 72 (6), 1300-1312 (2022)
   PUBMED   35562522
  REMARK    GeneRIF: GABA Receptor SNPs and Elevated Plasma GABA Levels Affect
            the Severity of the Indian ASD Probands.
REFERENCE   4  (bases 1 to 10862)
  AUTHORS   Iyer,G.R., Utage,P., Devi,R.R., Vattam,K.K. and Hasan,Q.
  TITLE     Expanding the clinico-molecular spectrum of Angelman syndrome
            phenotype with the GABRG3 gene: Evidence from methylation and
            sequencing studies
  JOURNAL   Ann Hum Genet 86 (2), 71-79 (2022)
   PUBMED   34779508
  REMARK    GeneRIF: Expanding the clinico-molecular spectrum of Angelman
            syndrome phenotype with the GABRG3 gene: Evidence from methylation
            and sequencing studies.
REFERENCE   5  (bases 1 to 10862)
  AUTHORS   Hou,S.J., Tsai,S.J., Kuo,P.H., Lin,W.Y., Liu,Y.L., Yang,A.C.,
            Lin,E. and Lan,T.H.
  TITLE     An association study in the Taiwan Biobank elicits the GABAA
            receptor genes GABRB3, GABRA5, and GABRG3 as candidate loci for
            sleep duration in the Taiwanese population
  JOURNAL   BMC Med Genomics 14 (1), 223 (2021)
   PUBMED   34530807
  REMARK    GeneRIF: An association study in the Taiwan Biobank elicits the
            GABAA receptor genes GABRB3, GABRA5, and GABRG3 as candidate loci
            for sleep duration in the Taiwanese population.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 10862)
  AUTHORS   Poulsen,C.F., Christjansen,K.N., Hastrup,S. and Hartvig,L.
  TITLE     Identification and cloning of a gamma 3 subunit splice variant of
            the human GABA(A) receptor
  JOURNAL   Brain Res Mol Brain Res 78 (1-2), 201-203 (2000)
   PUBMED   10891602
REFERENCE   7  (bases 1 to 10862)
  AUTHORS   Whiting,P.J., Bonnert,T.P., McKernan,R.M., Farrar,S., Le
            Bourdelles,B., Heavens,R.P., Smith,D.W., Hewson,L., Rigby,M.R.,
            Sirinathsinghji,D.J., Thompson,S.A. and Wafford,K.A.
  TITLE     Molecular and functional diversity of the expanding GABA-A receptor
            gene family
  JOURNAL   Ann N Y Acad Sci 868, 645-653 (1999)
   PUBMED   10414349
  REMARK    Review article
REFERENCE   8  (bases 1 to 10862)
  AUTHORS   Hadingham,K.L., Wafford,K.A., Thompson,S.A., Palmer,K.J. and
            Whiting,P.J.
  TITLE     Expression and pharmacology of human GABAA receptors containing
            gamma 3 subunits
  JOURNAL   Eur J Pharmacol 291 (3), 301-309 (1995)
   PUBMED   8719414
REFERENCE   9  (bases 1 to 10862)
  AUTHORS   Greger,V., Knoll,J.H., Woolf,E., Glatt,K., Tyndale,R.F.,
            DeLorey,T.M., Olsen,R.W., Tobin,A.J., Sikela,J.M., Nakatsu,Y. et
            al.
  TITLE     The gamma-aminobutyric acid receptor gamma 3 subunit gene (GABRG3)
            is tightly linked to the alpha 5 subunit gene (GABRA5) on human
            chromosome 15q11-q13 and is transcribed in the same orientation
  JOURNAL   Genomics 26 (2), 258-264 (1995)
   PUBMED   7601451
REFERENCE   10 (bases 1 to 10862)
  AUTHORS   Togel,M., Mossier,B., Fuchs,K. and Sieghart,W.
  TITLE     gamma-Aminobutyric acidA receptors displaying association of gamma
            3-subunits with beta 2/3 and different alpha-subunits exhibit
            unique pharmacological properties
  JOURNAL   J Biol Chem 269 (17), 12993-12998 (1994)
   PUBMED   8175718
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC127511.7, DN990720.1,
            S82769.1, AC104002.5 and BC029850.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_033223.4.
            
            Summary: This gene encodes a gamma-aminobutyric acid (GABA)
            receptor. GABA is the major inhibitory neurotransmitter in the
            mammalian brain where it acts at GABA-A receptors, which are
            ligand-gated chloride channels. Chloride conductance of these
            channels can be modulated by agents such as benzodiazepines that
            bind to the GABA-A receptor. GABA-A receptors are pentameric,
            consisting of proteins from several subunit classes: alpha, beta,
            gamma, delta and rho. The protein encoded by this gene is a gamma
            subunit, which contains the benzodiazepine binding site. Two
            transcript variants encoding distinct isoforms have been found for
            this gene. [provided by RefSeq, Aug 2012].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803612.44107.1,
                                           SRR1803617.21517.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA2145313
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000615808.5/ ENSP00000479113.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-101               AC127511.7         148124-148224       c
            102-531             DN990720.1         9-438
            532-1317            S82769.1           209-994
            1318-1318           AC104002.5         45897-45897         c
            1319-2105           BC029850.1         1129-1915
            2106-10862          AC104002.5         31443-40199         c
FEATURES             Location/Qualifiers
     source          1..10862
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q12"
     gene            1..10862
                     /gene="GABRG3"
                     /note="gamma-aminobutyric acid type A receptor subunit
                     gamma3"
                     /db_xref="GeneID:2567"
                     /db_xref="HGNC:HGNC:4088"
                     /db_xref="MIM:600233"
     exon            1..408
                     /gene="GABRG3"
                     /inference="alignment:Splign:2.1.0"
     exon            409..557
                     /gene="GABRG3"
                     /inference="alignment:Splign:2.1.0"
     exon            558..625
                     /gene="GABRG3"
                     /inference="alignment:Splign:2.1.0"
     exon            626..846
                     /gene="GABRG3"
                     /inference="alignment:Splign:2.1.0"
     exon            847..929
                     /gene="GABRG3"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1067
                     /gene="GABRG3"
                     /inference="alignment:Splign:2.1.0"
     exon            1068..1220
                     /gene="GABRG3"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1417
                     /gene="GABRG3"
                     /inference="alignment:Splign:2.1.0"
     exon            1418..1477
                     /gene="GABRG3"
                     /inference="alignment:Splign:2.1.0"
     exon            1478..10862
                     /gene="GABRG3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4299..4304
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GABRG3"
                     /note="hexamer: AATACA"
     polyA_site      4316
                     /gene="GABRG3"
     regulatory      10839..10844
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GABRG3"
                     /note="hexamer: AATAAA"
     polyA_site      10862
                     /gene="GABRG3"
                     /note="major polyA site"
ORIGIN      
        1 gcacagcgca cacagccccg gcctgggcac ccgcgcccgc tcgcggctcc aggcggggtg
       61 ggcggcgccg cgccaggggg tccccggcgc ccattgctcc cgccgcccgg ttgcgcggac
      121 cggcgctagt gcgcgggtgg gggcggcgcg ccgcggtggc ccggcgtccc gtgtgcgtcc
      181 agtgtgcgcc ccgcgggggc gcggccagcg ccagagtaga tacctgtccc gcccgccgcg
      241 gccagcagcc tcggaggaag ccagggcaaa gagggccggc ggagaccagg tccgcgccgg
      301 aggaagccgc gcccggccga ggccccggac cctgcgcccc gagctccacg gcaccatggc
      361 cccgaagctg ctgctcctcc tctgcctgtt ctcgggcttg cacgcgcggt ccagaaaggt
      421 ggaagaggat gaatatgaag attcatcatc aaaccaaaag tgggtcttgg ctccaaaatc
      481 ccaagacacc gacgtgactc ttattctcaa caagttgcta agagaatatg ataaaaagct
      541 gaggccagat attggaataa aaccgaccgt aattgacgtt gacatttatg ttaacagcat
      601 tggtcctgtg tcatcaataa acatggaata ccaaattgac atattttttg ctcagacctg
      661 gacagatagt cgccttcgat tcaacagcac aatgaaaatt cttactctga acagcaacat
      721 ggtggggtta atctggatcc cagacaccat cttccgcaat tctaaaaccg cagaggctca
      781 ctggatcacc acacccaatc agctcctccg gatttggaat gacgggaaaa tcctttacac
      841 tttgaggctc accatcaatg ctgagtgcca gctgcagctg cacaacttcc ccatggacga
      901 acactcctgc ccgctgattt tctccagcta tggctatccc aaagaagaaa tgatttatag
      961 atggagaaaa aattcagtgg aggcagctga ccagaaatca tggcggcttt atcagtttga
     1021 cttcatgggc ctcagaaaca ccacagaaat cgtgacaacg tctgcaggtg attatgttgt
     1081 catgactata tattttgaat tgagtagaag aatgggatac ttcaccattc agacatacat
     1141 tccctgtata ctgactgtgg ttttatcctg ggtgtcattt tggatcaaaa aagatgctac
     1201 gccagcaaga acagcattag gcatcaccac ggtgctgacc atgaccaccc tgagcaccat
     1261 cgccaggaag tccttgccac gcgtgtccta cgtgaccgcc atggaccttt ttgtgaccgt
     1321 gtgcttcctg tttgtcttcg ccgcgctgat ggagtatgcc accctcaact actattccag
     1381 ctgtagaaaa ccaaccacca cgaagaagac aacatcgtta ctacatccag attcctcaag
     1441 atggattcct gagcgaataa gcctacaagc cccttccaac tattccctcc tggacatgag
     1501 gccaccacca actgcgatga tcactttaaa caattccgtt tactggcagg aatttgaaga
     1561 tacctgtgtc tatgagtgtc tggatggcaa agactgtcag agcttcttct gctgctatga
     1621 agaatgtaaa tcaggatcct ggaggaaagg gcgtattcac atagacatct tggagctgga
     1681 ctcgtactcc cgggtctttt tccccacgtc cttcctgctc tttaacctgg tctactgggt
     1741 tggatacctg tatctctaag tgttgctcag agtgaagagt gaagagcatt tggtacacac
     1801 ttgaccttct gtcgtcccca gaccagtagt gaccaatcgg gagtagcaag gaaggacact
     1861 gcccagtgta tcttgttata aatgaccttt cagcaacaca ggaagtaccc agcaaaggtt
     1921 tctattatgt attttacaca cacacataca tacacacaca cagctaattg agttttaaag
     1981 taatattctt gctaatccct actgaattgt agcttggtgt tgtttctgaa tggtttttgg
     2041 atattggaag cagccgctga ttacccttgc aaagaaatct gtaaaatgtg cacgtgaatg
     2101 tctgagatgc tctctcaggc ctctagtcct tctgtatctt tcctttgcag ccctgggtgt
     2161 agtagcactc aggagtgttg aatcacccct ggccgagacc cactcctgct ggctcagcct
     2221 gggcatgtgt gtgctccagt gtgaacagca gtgggttcca accccagtct cctttctctg
     2281 tggcctctct ggctccagca ccatcatcgt tagctggcac tcctttacct aataacctcg
     2341 ttctaggcct ggggagagta cactcgcatt gtctacggtt tccattggag gagaaaataa
     2401 gattttcaaa atgctcatgt tgttggggtc aaagatgatt atctctgaac atcagaaggt
     2461 tattacttta ttccaactta ctgagagtca acaatatttg aactttgggt tcttggacta
     2521 gttcaacagc atttcacctt aagagctgtt tttcactaga ccaacgctca accctcgagt
     2581 atgtgtccag cttatgttat attattatgg gttcggtaat tgtcattttg caaagaaagg
     2641 tatacagtga acacaacctg ttatcttgaa gacatacacc ggaatgtgaa agacatgtag
     2701 ataaaatttt atttttattt tatttttttg agacagagtc atgctctgtc acctggccag
     2761 gctggagtgc agtggcacaa tcttagctca ctgcaacctc tgcctcccat gttcaagcga
     2821 ttttcctgcc tcagtttccc aagtggctgg gactacaggt gtgcgctacc acacccggct
     2881 aatttttgta tttttgtttt ttgttttttg ggttttttta gtagagacgg ggtttcacca
     2941 tgttggcctg gctggtctcg aactcctgac ctcaggtgat ctgcccgcct cagcctccca
     3001 aagtgctagg attacaggca tgagccacca tgcccggcca aaattaaaaa aaaaaaatta
     3061 gtgaatatta attttcaact caaaccaact ttagatgcaa aaaaatgggc aatggtgatc
     3121 atcaagtaca tattttgatg aacaagatta ttttatactt tgaaatatgg atacatagca
     3181 aaatcccaaa gaaaaaatat ccccccaaat caatactctt ttgatatttt tataatacaa
     3241 aaccaacttg ctgcttgctg ttagttcttt gttataactg gatgccaatg tgaactgcag
     3301 aagactgttt tgaaacttct cctcaccaat aggcaaaaca caagtcctac cagttagtta
     3361 ataatgcttt ggcattgtta aaatttgaaa ccagaatctc tgtgcttctc atctttctca
     3421 catagaaaac tgaattaatt tgacctagaa accgtaattt ttaaaattat ctattgtgca
     3481 taccataatt acccagaaac gtaaaatatt ttgcagagaa agtatagaaa agtatcaatt
     3541 tcacacaatg tcctggatgt ataccagaca cagaagagga tgggagcaga agaggccaga
     3601 aaaagtgaaa ttagattcat ctgcttattc ctattaagat tgttgcatat taaacggatg
     3661 caaagatata gatatgtctg aatttccaaa gatggagtct atacagcgtg agacattcaa
     3721 acccattgtt tctctccctg tcaactctct gtcttttggt ttggtagttg ctacataatc
     3781 cacaagccaa ttggcttcag tttagcaaat tcagttttaa aaataaaaga gtatttgtgg
     3841 agaaacaggt tgaaaatatt gtcttagatg caatgtctcc tctattggag aatttcacac
     3901 tctggtactc tagttctgtc tctcatgcat aagcaacccc cgccttggca gaagtattct
     3961 gcaaggaccc tgaccaaagg aatccaagtc acaccacagc actgagcgcc aagggaaggt
     4021 ggcccaaggg cagtcttaag acacaatgtc aaacgttatg aatgggtaat ttctaacaag
     4081 ctgaagaact gcaacctgct acattgtaaa cgaagttctg gagagaactg aattttctag
     4141 aaaaattctt attgggagga aaataaccta aaacaacttt ttataacatg gatttgtttg
     4201 attttacctt aaaagaattt tactgatgcc ttgtgtttca aaaccactca acatttggat
     4261 attgttagca accctcctga aattttacat gtaggataaa tacaccaata acctcagttt
     4321 tctgaatcca gccattctct tcttcccaac ctcagcagcc ctcctgatca aaacagatga
     4381 gttcagcgct ccttttctag gaaggagaac cttcatctca agaaagtcca atggatttca
     4441 ctaactgagc atcatagtgt ggattcctgc atatacagca ggctccccac tagggggtct
     4501 caataaaaag agctaaagca ccccctaaga gcatgtccat gccgggttct ccgcaggctt
     4561 gcataattca agttctccat atcagtctca actcctgaga tgagcctttt cagtccacaa
     4621 tgaggaagag atgggtgtgc cttggtgagg tgcagagctc aggggatttt taatcatgta
     4681 catgtttact ttctagagga aggagaggag cagtgtgggg agagtgggaa ggaagtacgc
     4741 tttctttcac taaagactct ctttgccagg atgcctgatc aggagggacg tgtgtgggca
     4801 cgaggtgcaa ggctgttcca cacagctaag ccccagcttg ctttgcatgc agaattggga
     4861 aatatttggg gtggaagttg tctgagtgat ctgcattcca aaggtgctac tgtgttcctc
     4921 actttcagaa atactctaag ttgaggagat gacagttctg tattttgaca tggaatccaa
     4981 atttctgacc actgtggatc acacttaaaa ctgtgactgt ctgtctttta agctgcatac
     5041 tgggtggggg gaaagcaaag aaaaggcatt tcacattaat ggaattggag aaaaatgtct
     5101 cttcagagcc tagaaagctt cagcttctgc aaagtcccaa caccacctac cagaacagag
     5161 actccctaca taccagacag agaaggacaa agttagtata atttactctg gacccagcca
     5221 atactgcccc caatttaccc aaaacatgcc ttaaaatgaa acagaaagct caaataatac
     5281 acatctttta agattttcca tttcctgcag ttagctatat ttcatgccaa gttttattta
     5341 tcttttatga atggatggaa ataggatttc atttctttat atgccaaaca gtcttaccct
     5401 taattttaca tcaaaccaat taagtacaaa gattttgcag gctctttgac tgagaaaatg
     5461 cgtgttctca agagcaaagc attttcactc tacataaggg aaattggggc caatctaaaa
     5521 tgtcagcaac acagtcctga tggggatgag tgtctctaat agaaactccg caccaaatca
     5581 ttttacctgg tgatagcttg ctgcagtaag tttgcaggca tgttgcttcg ttgttctgca
     5641 atataaccac actcgaagca acaggagagg ggccggtaac ccattctgca ttgactccag
     5701 ctccctatga ctaggaagca atgagccact ctatctaaag ggctagaaca caaaacagac
     5761 aaaacctctt cttccttgat catttttatc tcagctgcca aaatggaaat tttctgtgat
     5821 ttcctttgag acttgaagaa ttacacctgg tctccaacca ttattcttat caccgtatcg
     5881 gttcagtgct ctcaaggcac aaagcacttg gaattcactc catgatcttg caactctttt
     5941 tgagtgcttt tcctgagcga ttttaaactc tacccgtaag aaatttcatc tgcaatttct
     6001 gtaaaaaaaa aaaaaaaaaa aaagaatggc ttaagctcca cataatctga tgtaaatata
     6061 cattgaaacg ttaagttcta tttgtactga aacactgtcc accttagact ttagaacact
     6121 atcatttaac agatattcag aaaggttccg gaaatacggg ggaaagaacc agactacgaa
     6181 tacattggaa atgttaaatt tacaatattc tcctgagccc ccttccaatt tcccaaaatt
     6241 gagaaagtgt gtaatctgta cctatttttt ttctcaaatt ggcctggagg aaacattcag
     6301 gttcagagag tttagcagtg cctctatgtt tgtgttctct gtgtaatcac atgaaagaac
     6361 caacaaataa ctcttcagga taaatgacac ctgcatcgct gatcccttgt tgacttatgt
     6421 tttattataa aaatagatct ctatcattat agggataaaa cgtgtatgtt ttgagatgat
     6481 ttggtaagaa ctcagccatt cagtatttct ggaagaatta aaaacttggc tttctttttc
     6541 ttaatgtcta atagttttga agactagata ttagggcatt ttctttcctc cttttaaaat
     6601 ttctactgat tacaagctag caatttcagg atatcagctt gatctagttg tattaaggcc
     6661 aaaaggcaga ctttctttat atttattttt attatttatt tatttattta tttatttatt
     6721 tatttattta ttttgagatg aagttttact cttgttgccc aggctggagt gcagtggcgc
     6781 catctcggct cactgcaacc tccacctccc gggttcaagc aattctcttg cctcagcttc
     6841 ccgagtagct gggattacag gcacccacca ccatgtctgg ctaatttttt atatttttag
     6901 tagagatggg ctttcaccat gttggccagg ctggtctcga actcctgacc ttcaggtgat
     6961 ccacccgcct tggcctccca aagtactggg attacaggcg tgagccaccg cgcccaacct
     7021 gtatttactt ttttaatgcc acctagctga ataatgcttt gggttttact gttgtcaata
     7081 aaacccctta taccttttat tgtcctgctt acttataaaa gccaaatttt aggcgaactt
     7141 aaataaatca gtgctgaaaa actagttgaa caatcagtca ctgacaagtt ttcaatgttt
     7201 tgagttaacc aagtgggctt ttcagattag gttattcaag agcatgagct agaaaataat
     7261 taggcagaca aaacatatgt tctcacacac acaccacttc caaaacagac atgatttgaa
     7321 tgtagcattc aggttattga ggtgaacgta aattgctttg cttgaacaat tgagataatc
     7381 acctactttc gccacttcac ttttcacatt tgtaaacaca cacagggttt ttccagccca
     7441 gtgagcaggc tacacaatgt gaggatgata atggttcctg cagggaagcc agagcctcta
     7501 tgtctgccga acagtttaaa ttgaacaggt tggaaagaac attgattgcc aataattaaa
     7561 tgccccagac tgagcaggta gctgctacat tttctcttct cttttctagt tattcagggt
     7621 tccttctttg attttcatga gaaaggaaca tttacacttc ctgtgagggg cttagactcc
     7681 gatttctccc agttgcctca cttactgaag ttcgatccca gtgaatgatg tgtatgtacc
     7741 caacacatcc aatttgtatt ttcttaaata tgtgtttctt aggtatctaa ggatacatga
     7801 gcgagcccac agcacaatta ttgcagtccc caagatgtca gtcttctcaa aatgacaaca
     7861 ttgtcactaa ccacttttta aaaaagaact gaaattccca ttttttgtta aacgtttttc
     7921 caatacatag caatgtgtaa aatagactcc caaatctcct ttgggaaagg aacctgtgga
     7981 ccctggagct aagttgtcat tttagggaca tggtgataat caggactgat gccagtaagt
     8041 gggaagttca ttacggcaag gcagtgggaa ggtgccagca tcccctttcc acctgagatg
     8101 ggctgaattt tcacccggaa gtctgaagcc tctggaaggg caggtggaat cgctcctggc
     8161 aagggcatga ccgtgcacag gctgacatga ttttcctttt gggtggattg gagttttaca
     8221 actggattca ttagcacacg tgtgggaaca tgtgcctgtg cccacccaca gcacttcctt
     8281 ggaactctaa gctgcttctc taatctaagg aggtctattc gaaaggatag tgcttgactt
     8341 tcaatttata aaagattatt ggaaacacct taagtagtcc taacccactg tcagcttcca
     8401 attttcagga gcaaatgatg actgctttga tttggttagg ctttcttaca acaggttttt
     8461 ataaaatatt gtttatattt gtaacaggaa ggattttcaa tgtcaatttc atccatgagt
     8521 gaagaccccc cactgcacag agcagcactt ctgtcactct catggggaga tcagggtacc
     8581 cactcctcta cgtagcttgg cagacccaga ccaccctgag ccagcctgcc acatccgcta
     8641 gtccatgcac ctccagggtg gccttgggag ctacagagag gaaaaaaaga aaaaatgttg
     8701 cattcttaag caattaaaga ctccttccaa tgtaattaaa aaataagtaa tgtggcaaaa
     8761 gatgcacata acttgctccc tcaagttcta aattgtcacc aaatatgaaa ggtttttaga
     8821 tgaagtacat ctacatcata accatcatca ccctcattgt cctcttccat gtttctacta
     8881 gtactcagct attgattcaa cacaaaggct tagagccttt tctgaactat aacgaaatca
     8941 gaacttacat cgtggaaaaa gcgaaaaagt ttcattagag tttaaacatt aagtatacag
     9001 atcctactcc aaaattttgc tcgcctaaaa catttccaga actgctgtgt tccccagcag
     9061 tcctgcctgc cctgcctcaa tcagaatttc aaattactat ttagaagaac attccattca
     9121 attgttgttt gttgattgct ttctctcttt ttttttccgt ttttacctta gttggctatt
     9181 ttattccttt tcgtaaagat aacgtttgaa ttgtctaaca actatctttt ttcactaaaa
     9241 tacatgcatc tttggaaact gcaaattttg tgagctcaaa aagacaatca ctgtgcttct
     9301 tatcatctaa tttgagtcta ggctttgttt ccccctaact tatcctggca tttttacttt
     9361 gaatagaaat agtcacaggc aaaatatatt catgaaatgt acagtgctta ctattatatg
     9421 atctctgttt agaataacta ttttattaaa acagtctaaa agacactgtc catcattctt
     9481 gacatttgat atgtctaatt ttgtgctagt gaaccaagtt tacctgctca cacgtttgta
     9541 caactacaca atgtgttttc ctttacgtgc agctccggta ctgagcaaaa ggttcgttgt
     9601 ttaggagtga aattttctgt gaaagttttg ggagagtaat tattttcagg gatcagacct
     9661 atgtgttgtt aggagcaaga ggccatcttg tgtttacatg cagtggtctg tgtatttgtg
     9721 tctgtacgta cagtggtaaa actgaaacaa cttattaata atgtgtgtca ctctacccat
     9781 caccccaaat ttagctgaaa caagtagaaa ggagcgcagt tttctagcga tagcgtatta
     9841 gcactaagcc tctggttagg ataaaaagga gcaagggaga gggagaaaga gaggacagag
     9901 ggagagagag aaagtggcaa tctgtacatt tcctgacaaa gtgggatcat gttctttcca
     9961 agaaaaggaa aagaaatcca gcttcactac ctgatcagga gtccctctgg ggtccacaca
    10021 agcctgcctc ctttggagag cccttgagca tcactgttgt gaccggggtg cacacctggg
    10081 cgactccttg atcattcgtg cattctggtc aagttgaccc gataagccaa aagtactttt
    10141 caagatttag atggcaaaca gccatcccca cccttgtcta ggaagtcgta ttcgcaggtc
    10201 acaggaaggc gtcaggtcag gcttgaagca gccggggtgt gggcagggtc ctctctctgt
    10261 gaagcctgtg tgggaggtga aactgtcagg ggtcctggga gatggcccag gcaggaaggg
    10321 aaggagagag gcgcggactg ctctctgttc ccatggaatc cttcctgcct gtgaagccat
    10381 tgtcctccag atgggaggta ggccgggaga ttccagaatc cgaaaacatt ttggaatcat
    10441 cttagagcac cggtgtggat gcgcttggcc ccgagggggc cgcgccctgc cccagtgcgt
    10501 gcgcctcctg ccccagcagg gacccgccct caccaagtgg cctccagtag cccctgtgtc
    10561 cctgtcgtcc cgcgagggat tggaggccct ggctccgggc ggtcccgagg tcccgccgcc
    10621 ctcctcccct gcgcagagga cgtggctccc cgctatccgt gcggctcgtg gtgtcctagt
    10681 gaaatgaggg cgcactggcg cccgacgtgc cttggcgaca cgggcggcgc cgcgccccgc
    10741 ttcgtgcgtc ccgtccccgc cgtgccctca gctgggcctc gtggctgggc cgccctctgt
    10801 atttgtattt ggattcctac gtttgtactt ctaatacaaa taaatgcaca tgttgtcaga
    10861 aa
//
