LOCUS       XM_047427936            5954 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens GRB2 associated binding protein 2 (GAB2),
            transcript variant X3, mRNA.
ACCESSION   XM_047427936
VERSION     XM_047427936.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000011.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5954
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
     gene            1..5954
                     /gene="GAB2"
                     /note="GRB2 associated binding protein 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 13 ESTs, 572 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 3 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:9846"
                     /db_xref="HGNC:HGNC:14458"
                     /db_xref="MIM:606203"
     CDS             59..1975
                     /gene="GAB2"
                     /codon_start=1
                     /product="GRB2-associated-binding protein 2 isoform X2"
                     /protein_id="XP_047283892.1"
                     /db_xref="GeneID:9846"
                     /db_xref="HGNC:HGNC:14458"
                     /db_xref="MIM:606203"
                     /translation="MSGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAGLTFNKKELQD
                     SFVFDIKTSERTFYLVAETEEDMNKWVQSICQICGFNQAEESTDSLRNVSSAGHGPRS
                     SPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHMQPTLSTSAPQEYLYLHQC
                     ISRRAENARSASFSQGTRASFLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSR
                     HNTEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVDNM
                     DVPATPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQR
                     PPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGV
                     GSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDS
                     LGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPIT
                     KSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPA
                     PKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWT
                     DVRQSSEPSKGAKL"
ORIGIN      
        1 aaatggtgga ctagaccagg cctggaagaa acgctggttt atcctgcgga gtggccggat
       61 gagcggtgac ccagatgttc tggaatacta caagaacgat cactccaaga agcctctgcg
      121 gatcatcaac ctgaacttct gtgagcaggt agatgcaggc ctgaccttta acaagaagga
      181 gctgcaggat agttttgtgt ttgacatcaa gaccagtgaa cgcacctttt acctggtggc
      241 tgagacagaa gaggacatga ataagtgggt ccagagcatc tgccagatct gtggcttcaa
      301 tcaggctgag gagagcacag actccctgag aaatgtttcc tcagccggtc atggcccccg
      361 ctcttctcca gctgagctca gcagctctag ccagcacctt ctccgagagc gcaagtcctc
      421 agccccatca cactccagcc agccaactct gttcacgttt gaaccccctg tgtcaaacca
      481 catgcagccc accttgtcca ccagcgcacc tcaggagtat ctctacttgc accagtgcat
      541 aagccgaaga gcagaaaatg caaggagtgc cagcttctct cagggcacca gagcctcttt
      601 tctcatgagg agtgacacag ctgtacaaaa acttgcccag ggcaatggac actgtgtcaa
      661 cgggatcagt ggtcaagtcc atggcttcta tagccttccc aagccgagcc ggcacaatac
      721 agaattcaga gacagtacct acgacctccc ccgcagcctg gcctcccatg gccacaccaa
      781 gggcagcctc acaggctccg agacagataa tgaggatgtg tacaccttca agacgcccag
      841 caacaccctg tgcagggagt tcggggacct cctggtagac aatatggatg ttccggccac
      901 cccactctca gcctaccaga tccctaggac attcactctg gacaaaaacc acaatgccat
      961 gacagtggcc actcctgggg actcagccat agctccccca ccccgccccc ccaagccaag
     1021 tcaggcagaa acacctcgat ggggcagtcc tcagcagaga ccgccaatca gtgaaaatag
     1081 cagatctgtc gctgccacca tccccagacg caacaccctc cctgcaatgg acaacagccg
     1141 acttcaccga gcttcttcct gtgagaccta cgagtaccca cagcgtggtg gagagagtgc
     1201 aggccggtct gctgaatcca tgagtgatgg agttggctct ttcctgccag ggaaaatgat
     1261 tgtgggccga tcggacagca ccaattctga agacaactat gtgcccatga atccaggttc
     1321 ttccaccctg ttggccatgg aacgagcagg tgataattcc cagagcgtct acatcccaat
     1381 gagcccaggg gcccatcact ttgactcact tggctaccca tcaacaaccc ttcctgtgca
     1441 ccgaggcccc agcagaggaa gtgagattca gccaccccct gtcaaccgca acctcaaacc
     1501 tgatcggaaa gcaaagccaa caccacttga cctgaggaac aacaccgtca tcgatgaact
     1561 ccccttcaag tcacctatca ccaagtcttg gtctagggcc aaccacacct tcaactccag
     1621 ctcctcccag tactgccgcc ccatctccac ccagagcatc accagcacag actcaggaga
     1681 cagcgaagag aactatgtcc ctatgcaaaa cccagtgtct gcatctcccg ttcccagtgg
     1741 cacgaacagt cctgccccta agaagagcac cggcagcgtt gattatctgg ccctggactt
     1801 ccagccgagc tccccaagcc cccaccgcaa gccatctact tcatccgtca cctctgatga
     1861 gaaggtggac tacgttcagg tggacaagga gaagacccag gccctgcaga acaccatgca
     1921 ggagtggaca gacgtgcggc agtcctcaga gccttccaag ggtgccaagc tgtgatgaga
     1981 gggccaccgc agagcccagg aggcagcatc tccagagctg gcccttccca tctcccctct
     2041 cccctctccc gttcttcctc ccatccacct cctctctact ctgccagtct cagccttcaa
     2101 agcacttgac atcagggacc ctgaaccctt cccctgggag gtgagggcct gatcaaggca
     2161 cctcctctgc ccactcgggg cccagctgtg atttttatca gtaatggcca tgcctccacc
     2221 caccttagtt aggagctact tccaaaaagc atccttcagc ctcttcctgt cctttagacc
     2281 tgactctcta ccagatgttt ggagggaagg gctggggctc tgagccagat tccacacctc
     2341 acgttcagtc acagccctca gctatcttcc ctccggccac tgggctacct ctccttcagt
     2401 cccagaagac aagtctcacc aacccaggga gtcaaggacc agcaaaccaa agtggataat
     2461 ggactttttc attcctgttt ttcttggcag gagagaagca aggccactaa aagaggagat
     2521 ggtggagacg gaggctcagc agtggtcttg aggggtaaag gacttagatg cccagatgaa
     2581 gagggaaagc tgacatctgc agggaaccca ctttgaggct gaggccatgg caggacagct
     2641 gctgtggggt gcagaggcag aagatgaagg acaaaaggaa gggaaaactg atggccaacc
     2701 tagagcagca aggagcaggg cttggagctc gggtggtgga gatgacaagg acactgtggg
     2761 gtctgggtcc ccagaactct ggagctacag gccactctag gcccaagggc tagtcctctt
     2821 ccccagtccc ctcagaggcc cccgccagcc ccaccttgaa agcagcatac aggggaaggc
     2881 ttggaccaag ctgggcgacc aagcacatgg ggcaggaaca catggtaaag gggtggggaa
     2941 tatgggaggg agtgtggtgt ggatgggggt gatgcaggga ctgaggggaa ccctgggaca
     3001 ggcacaggct gggcagaggc acagggcagt gcaggggact ctgcagtggg gtcgggaagt
     3061 gagtttcttt gcagtgagca gtgcagtgga agtcgggcac agaggtagca gacagatgtg
     3121 aagcagtggt gaaggccatg tagcaagtgg ggaaatacat ccaaagggcc tgggagttgg
     3181 ggggtgccca acgcaatcct tgggggtgca gggtggagca gaaagtgaag gagggacacg
     3241 tgcaagagtg gtgtgcatgg tggtgtgaca tgaggaccgt tcctaggatg ggacagtggg
     3301 tcaggcagga caaggagaaa gcagggcaga atgatgccta gaggaccaca tcaggcatgg
     3361 ctgacagctt gtgcccatgg gctgtggcgt atgtcagatc gcagggtagg aacgagtctg
     3421 gcctggtgcc ggcccagtgt ttcctcagct catccgccct ctgttgctcc ctagcattcc
     3481 aggagccatc ttggactctc ctccccaggt ttgaaaggcc atcagattag cagggacggg
     3541 gtgtagggca tcacccaagg ttccttctct taaactaagg gtgggggatc tgaatgtttt
     3601 tatgttgact gttcttgact aaattttcaa gagtttcaga agcaacagga cagaccagac
     3661 gtttcattct accctggggc gaacagaact tcttcctccc aaacaatgac ttcctgccat
     3721 gtttgatggg gacagctacc actgtcctct gcccccattc ccctttcagc tcccatgagc
     3781 atgcatagtt caccagacca atggcctagc cattctctaa gtcccatcct ggaagaagtt
     3841 atttcttcaa gagctgcacc tctcctccta gcattagttt agatcaactc aaggagtatt
     3901 tattaatggc tgctgtctcc agtttctggg gttaagcact aaggacacaa gaatcaatca
     3961 gaccttctcc ctgaacttaa gatagccaca atcagaaaaa ggacaaggac atgagacagt
     4021 ggtgatggcc atcagacaga gacttcaaat gctgatggag ggcagaggaa gtacttaggg
     4081 aggttggtgt cagaggcagg agtgggggat cagggaaggt ggattctagg aaaagggagt
     4141 gcctgaggta ggccttagaa ggggatgagt cagattttta cagaggagga gggcagggct
     4201 tgggtccagt ggaggaagaa ggaaggagag gcttggaaag ccttgtgtct tgggaacaaa
     4261 aggcctttga gcatatgggt ccagccactc agaagtgtag gggccatgcc ttggtgttcc
     4321 aataagtgaa tggaagcagt ggtggtagct acactgggca gagttggcag ggtgctggtt
     4381 cactctgccc agccctgaat gtgtgcctta aaggccccct acaaggggcc ccatacgaca
     4441 gagcttttaa ctggtgcctt ccctgtaccc gcagcagcca caagtgggcc cagactattg
     4501 cagcctccca taaacatgtg agcatgttct gagtgtgcca tgatgtgagt ggacctggct
     4561 ggaatcttcg gagagcgact gaggtgttca aatcgaatct cccaggaggc ttccttccag
     4621 ccccctattc tggtaactac caggaggctt ccttccagcc ccctattctg gtaactacca
     4681 aaatccctcg ggtgcaagtg taggggtaga gatggaagga tgagaggtga aattgacctt
     4741 ttgaaagcaa agctctggct cacaggcccc aaactaccag ccgtatctag catatcccca
     4801 ccctccaccc actacctcct ccaacaaagg agtcaactca gttgaaaaaa ctggtccttt
     4861 ggcctatcca tgggtcaaag tccacctctc ctgggggcct ggagaggact gagcctacgg
     4921 aaaggggata ccttcccact cagcactgct tcacacaggc cccctgcctg gggctctcca
     4981 aggagccttc ttcacccact tccagctcca cttctgcaag gttaagtcaa gtgagaacga
     5041 tgagaaatag ggagatggtg tctccttaag tccttgatct gcctgtctgt ggaatgggag
     5101 gttggattag ctgcgctgag gtcccatcca cagctggtgc tcagctgctt gaaggggaga
     5161 ctccctcctc tgtaacttct ttctggggga ttggggtggg cagtacctat ccccagtccc
     5221 ctcctagctt gactttagtg gtttccaatg tagaagttaa caaagtatgc cccattcctg
     5281 tgacaaaagc acaaccattc tgaagttact ggagcatggg ctcagctcat cctccctctg
     5341 gccccttctc ccatggggac atctcggccc agcaccccta tcccatttcc agagttcttc
     5401 cttccccatc tgggccttca taaaatgcag gggaagccag actggtctca ggagcgctaa
     5461 agcccttccg tggggggtcg tctttctggg actagccctg ctgtttagga cctgggacca
     5521 caatggggta cctgccgagg gggtccccaa gagatccagg ctgtcatgtg atttatggtg
     5581 gcatgtgttg tgtatttgtt ggctacttgt gtcttgaaat ctagaattat ttcacgcaga
     5641 attgtcactg tttgtcagga agagaaaatg ggctagtgga agcccagtct tgagttcttg
     5701 tcttgttacc atttaaaatt gacatttaat tttcaaatca ctgttggtgc ctaatcactt
     5761 aagttattaa tttattctgt tgtattcttt tttttaaatt gtaacatatt tatccggtgg
     5821 gtgggacagg agtgtgttca agtgggtcat gtttttgctg tggtgacaca tggtacaggc
     5881 ttggagcttg caggtccctt tctactgtgg tgttggagca ggacaataaa gtccactaga
     5941 aatgcacccc agaa
//
