LOCUS       XM_024448782            6058 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens GRB2 associated binding protein 2 (GAB2),
            transcript variant X1, mRNA.
ACCESSION   XM_024448782
VERSION     XM_024448782.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000011.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_024448782.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6058
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
     gene            1..6058
                     /gene="GAB2"
                     /note="GRB2 associated binding protein 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 13 ESTs, 577 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 6 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:9846"
                     /db_xref="HGNC:HGNC:14458"
                     /db_xref="MIM:606203"
     CDS             103..2079
                     /gene="GAB2"
                     /codon_start=1
                     /product="GRB2-associated-binding protein 2 isoform X1"
                     /protein_id="XP_024304550.1"
                     /db_xref="GeneID:9846"
                     /db_xref="HGNC:HGNC:14458"
                     /db_xref="MIM:606203"
                     /translation="MASAQEKAWKKRWFILRSGRMSGDPDVLEYYKNDHSKKPLRIIN
                     LNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLVAETEEDMNKWVQSICQICGFNQ
                     AEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSN
                     HMQPTLSTSAPQEYLYLHQCISRRAENARSASFSQGTRASFLMRSDTAVQKLAQGNGH
                     CVNGISGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYT
                     FKTPSNTLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPP
                     PRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYE
                     YPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERA
                     GDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPT
                     PLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENY
                     VPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDEKVD
                     YVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAKL"
ORIGIN      
        1 agtggtgaag aggcagcatt aaggaaaaga ctagccccag ttctctccta agagccattt
       61 cagcccactt cagtctatta gattgaagat gctggaaggc gaatggcttc agcacaggaa
      121 aaggcctgga agaaacgctg gtttatcctg cggagtggcc ggatgagcgg tgacccagat
      181 gttctggaat actacaagaa cgatcactcc aagaagcctc tgcggatcat caacctgaac
      241 ttctgtgagc aggtagatgc aggcctgacc tttaacaaga aggagctgca ggatagtttt
      301 gtgtttgaca tcaagaccag tgaacgcacc ttttacctgg tggctgagac agaagaggac
      361 atgaataagt gggtccagag catctgccag atctgtggct tcaatcaggc tgaggagagc
      421 acagactccc tgagaaatgt ttcctcagcc ggtcatggcc cccgctcttc tccagctgag
      481 ctcagcagct ctagccagca ccttctccga gagcgcaagt cctcagcccc atcacactcc
      541 agccagccaa ctctgttcac gtttgaaccc cctgtgtcaa accacatgca gcccaccttg
      601 tccaccagcg cacctcagga gtatctctac ttgcaccagt gcataagccg aagagcagaa
      661 aatgcaagga gtgccagctt ctctcagggc accagagcct cttttctcat gaggagtgac
      721 acagctgtac aaaaacttgc ccagggcaat ggacactgtg tcaacgggat cagtggtcaa
      781 gtccatggct tctatagcct tcccaagccg agccggcaca atacagaatt cagagacagt
      841 acctacgacc tcccccgcag cctggcctcc catggccaca ccaagggcag cctcacaggc
      901 tccgagacag ataatgagga tgtgtacacc ttcaagacgc ccagcaacac cctgtgcagg
      961 gagttcgggg acctcctggt agacaatatg gatgttccgg ccaccccact ctcagcctac
     1021 cagatcccta ggacattcac tctggacaaa aaccacaatg ccatgacagt ggccactcct
     1081 ggggactcag ccatagctcc cccaccccgc ccccccaagc caagtcaggc agaaacacct
     1141 cgatggggca gtcctcagca gagaccgcca atcagtgaaa atagcagatc tgtcgctgcc
     1201 accatcccca gacgcaacac cctccctgca atggacaaca gccgacttca ccgagcttct
     1261 tcctgtgaga cctacgagta cccacagcgt ggtggagaga gtgcaggccg gtctgctgaa
     1321 tccatgagtg atggagttgg ctctttcctg ccagggaaaa tgattgtggg ccgatcggac
     1381 agcaccaatt ctgaagacaa ctatgtgccc atgaatccag gttcttccac cctgttggcc
     1441 atggaacgag caggtgataa ttcccagagc gtctacatcc caatgagccc aggggcccat
     1501 cactttgact cacttggcta cccatcaaca acccttcctg tgcaccgagg ccccagcaga
     1561 ggaagtgaga ttcagccacc ccctgtcaac cgcaacctca aacctgatcg gaaagcaaag
     1621 ccaacaccac ttgacctgag gaacaacacc gtcatcgatg aactcccctt caagtcacct
     1681 atcaccaagt cttggtctag ggccaaccac accttcaact ccagctcctc ccagtactgc
     1741 cgccccatct ccacccagag catcaccagc acagactcag gagacagcga agagaactat
     1801 gtccctatgc aaaacccagt gtctgcatct cccgttccca gtggcacgaa cagtcctgcc
     1861 cctaagaaga gcaccggcag cgttgattat ctggccctgg acttccagcc gagctcccca
     1921 agcccccacc gcaagccatc tacttcatcc gtcacctctg atgagaaggt ggactacgtt
     1981 caggtggaca aggagaagac ccaggccctg cagaacacca tgcaggagtg gacagacgtg
     2041 cggcagtcct cagagccttc caagggtgcc aagctgtgat gagagggcca ccgcagagcc
     2101 caggaggcag catctccaga gctggccctt cccatctccc ctctcccctc tcccgttctt
     2161 cctcccatcc acctcctctc tactctgcca gtctcagcct tcaaagcact tgacatcagg
     2221 gaccctgaac ccttcccctg ggaggtgagg gcctgatcaa ggcacctcct ctgcccactc
     2281 ggggcccagc tgtgattttt atcagtaatg gccatgcctc cacccacctt agttaggagc
     2341 tacttccaaa aagcatcctt cagcctcttc ctgtccttta gacctgactc tctaccagat
     2401 gtttggaggg aagggctggg gctctgagcc agattccaca cctcacgttc agtcacagcc
     2461 ctcagctatc ttccctccgg ccactgggct acctctcctt cagtcccaga agacaagtct
     2521 caccaaccca gggagtcaag gaccagcaaa ccaaagtgga taatggactt tttcattcct
     2581 gtttttcttg gcaggagaga agcaaggcca ctaaaagagg agatggtgga gacggaggct
     2641 cagcagtggt cttgaggggt aaaggactta gatgcccaga tgaagaggga aagctgacat
     2701 ctgcagggaa cccactttga ggctgaggcc atggcaggac agctgctgtg gggtgcagag
     2761 gcagaagatg aaggacaaaa ggaagggaaa actgatggcc aacctagagc agcaaggagc
     2821 agggcttgga gctcgggtgg tggagatgac aaggacactg tggggtctgg gtccccagaa
     2881 ctctggagct acaggccact ctaggcccaa gggctagtcc tcttccccag tcccctcaga
     2941 ggcccccgcc agccccacct tgaaagcagc atacagggga aggcttggac caagctgggc
     3001 gaccaagcac atggggcagg aacacatggt aaaggggtgg ggaatatggg agggagtgtg
     3061 gtgtggatgg gggtgatgca gggactgagg ggaaccctgg gacaggcaca ggctgggcag
     3121 aggcacaggg cagtgcaggg gactctgcag tggggtcggg aagtgagttt ctttgcagtg
     3181 agcagtgcag tggaagtcgg gcacagaggt agcagacaga tgtgaagcag tggtgaaggc
     3241 catgtagcaa gtggggaaat acatccaaag ggcctgggag ttggggggtg cccaacgcaa
     3301 tccttggggg tgcagggtgg agcagaaagt gaaggaggga cacgtgcaag agtggtgtgc
     3361 atggtggtgt gacatgagga ccgttcctag gatgggacag tgggtcaggc aggacaagga
     3421 gaaagcaggg cagaatgatg cctagaggac cacatcaggc atggctgaca gcttgtgccc
     3481 atgggctgtg gcgtatgtca gatcgcaggg taggaacgag tctggcctgg tgccggccca
     3541 gtgtttcctc agctcatccg ccctctgttg ctccctagca ttccaggagc catcttggac
     3601 tctcctcccc aggtttgaaa ggccatcaga ttagcaggga cggggtgtag ggcatcaccc
     3661 aaggttcctt ctcttaaact aagggtgggg gatctgaatg tttttatgtt gactgttctt
     3721 gactaaattt tcaagagttt cagaagcaac aggacagacc agacgtttca ttctaccctg
     3781 gggcgaacag aacttcttcc tcccaaacaa tgacttcctg ccatgtttga tggggacagc
     3841 taccactgtc ctctgccccc attccccttt cagctcccat gagcatgcat agttcaccag
     3901 accaatggcc tagccattct ctaagtccca tcctggaaga agttatttct tcaagagctg
     3961 cacctctcct cctagcatta gtttagatca actcaaggag tatttattaa tggctgctgt
     4021 ctccagtttc tggggttaag cactaaggac acaagaatca atcagacctt ctccctgaac
     4081 ttaagatagc cacaatcaga aaaaggacaa ggacatgaga cagtggtgat ggccatcaga
     4141 cagagacttc aaatgctgat ggagggcaga ggaagtactt agggaggttg gtgtcagagg
     4201 caggagtggg ggatcaggga aggtggattc taggaaaagg gagtgcctga ggtaggcctt
     4261 agaaggggat gagtcagatt tttacagagg aggagggcag ggcttgggtc cagtggagga
     4321 agaaggaagg agaggcttgg aaagccttgt gtcttgggaa caaaaggcct ttgagcatat
     4381 gggtccagcc actcagaagt gtaggggcca tgccttggtg ttccaataag tgaatggaag
     4441 cagtggtggt agctacactg ggcagagttg gcagggtgct ggttcactct gcccagccct
     4501 gaatgtgtgc cttaaaggcc ccctacaagg ggccccatac gacagagctt ttaactggtg
     4561 ccttccctgt acccgcagca gccacaagtg ggcccagact attgcagcct cccataaaca
     4621 tgtgagcatg ttctgagtgt gccatgatgt gagtggacct ggctggaatc ttcggagagc
     4681 gactgaggtg ttcaaatcga atctcccagg aggcttcctt ccagccccct attctggtaa
     4741 ctaccaggag gcttccttcc agccccctat tctggtaact accaaaatcc ctcgggtgca
     4801 agtgtagggg tagagatgga aggatgagag gtgaaattga ccttttgaaa gcaaagctct
     4861 ggctcacagg ccccaaacta ccagccgtat ctagcatatc cccaccctcc acccactacc
     4921 tcctccaaca aaggagtcaa ctcagttgaa aaaactggtc ctttggccta tccatgggtc
     4981 aaagtccacc tctcctgggg gcctggagag gactgagcct acggaaaggg gataccttcc
     5041 cactcagcac tgcttcacac aggccccctg cctggggctc tccaaggagc cttcttcacc
     5101 cacttccagc tccacttctg caaggttaag tcaagtgaga acgatgagaa atagggagat
     5161 ggtgtctcct taagtccttg atctgcctgt ctgtggaatg ggaggttgga ttagctgcgc
     5221 tgaggtccca tccacagctg gtgctcagct gcttgaaggg gagactccct cctctgtaac
     5281 ttctttctgg gggattgggg tgggcagtac ctatccccag tcccctccta gcttgacttt
     5341 agtggtttcc aatgtagaag ttaacaaagt atgccccatt cctgtgacaa aagcacaacc
     5401 attctgaagt tactggagca tgggctcagc tcatcctccc tctggcccct tctcccatgg
     5461 ggacatctcg gcccagcacc cctatcccat ttccagagtt cttccttccc catctgggcc
     5521 ttcataaaat gcaggggaag ccagactggt ctcaggagcg ctaaagccct tccgtggggg
     5581 gtcgtctttc tgggactagc cctgctgttt aggacctggg accacaatgg ggtacctgcc
     5641 gagggggtcc ccaagagatc caggctgtca tgtgatttat ggtggcatgt gttgtgtatt
     5701 tgttggctac ttgtgtcttg aaatctagaa ttatttcacg cagaattgtc actgtttgtc
     5761 aggaagagaa aatgggctag tggaagccca gtcttgagtt cttgtcttgt taccatttaa
     5821 aattgacatt taattttcaa atcactgttg gtgcctaatc acttaagtta ttaatttatt
     5881 ctgttgtatt ctttttttta aattgtaaca tatttatccg gtgggtggga caggagtgtg
     5941 ttcaagtggg tcatgttttt gctgtggtga cacatggtac aggcttggag cttgcaggtc
     6001 cctttctact gtggtgttgg agcaggacaa taaagtccac tagaaatgca ccccagaa
//
