LOCUS       XM_047434609            1814 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens FTO alpha-ketoglutarate dependent
            dioxygenase (FTO), transcript variant X10, mRNA.
ACCESSION   XM_047434609
VERSION     XM_047434609.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000016.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1814
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
     gene            1..1814
                     /gene="FTO"
                     /gene_synonym="ALKBH9; BMIQ14; GDFD; IFEX9"
                     /note="FTO alpha-ketoglutarate dependent dioxygenase;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 ESTs, 592 long SRA reads, 2 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 10 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:79068"
                     /db_xref="HGNC:HGNC:24678"
                     /db_xref="MIM:610966"
     CDS             223..1596
                     /gene="FTO"
                     /gene_synonym="ALKBH9; BMIQ14; GDFD; IFEX9"
                     /codon_start=1
                     /product="alpha-ketoglutarate-dependent dioxygenase FTO
                     isoform X8"
                     /protein_id="XP_047290565.1"
                     /db_xref="GeneID:79068"
                     /db_xref="HGNC:HGNC:24678"
                     /db_xref="MIM:610966"
                     /translation="MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQL
                     KYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNP
                     GCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAK
                     EKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEE
                     PYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKI
                     SWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYI
                     LQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKC
                     TDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRR
                     EWHARVE"
     polyA_site      1814
                     /gene="FTO"
                     /gene_synonym="ALKBH9; BMIQ14; GDFD; IFEX9"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 ctacgctctt ccagctgtcg gacctgggaa attctcctgt gctaaatccc gtggcgctcg
       61 cgggtgtcgc cgcggtgcat cctgggagtt gtagtttttt ctactcagag ggagaatagc
      121 tccagacggg agcaggacgc tgagagaact acatgcagga ggcggggtcc agggcgaggg
      181 atctacgcag cttgcggtgg cgaaggcggc tttagtggca gcatgaagcg caccccgact
      241 gccgaggaac gagagcgcga agctaagaaa ctgaggcttc ttgaagagct tgaagacact
      301 tggctccctt atctgacccc caaagatgat gaattctatc agcagtggca gctgaaatat
      361 cctaaactaa ttctccgaga agccagcagt gtatctgagg agctccataa agaggttcaa
      421 gaagcctttc tcacactgca caagcatggc tgcttatttc gggacctggt taggatccaa
      481 ggcaaagatc tgctcactcc ggtatctcgc atcctcattg gtaatccagg ctgcacctac
      541 aagtacctga acaccaggct ctttacggtc ccctggccag tgaaagggtc taatataaaa
      601 cacaccgagg ctgaaatagc cgctgcttgt gagaccttcc tcaagctcaa tgactacctg
      661 cagatagaaa ccatccaggc tttggaagaa cttgctgcca aagagaaggc taatgaggat
      721 gctgtgccat tgtgtatgtc tgcagatttc cccagggttg ggatgggttc atcctacaac
      781 ggacaagatg aagtggacat taagagcaga gcagcataca acgtaacttt gctgaatttc
      841 atggatcctc agaaaatgcc atacctgaaa gaggaacctt attttggcat ggggaaaatg
      901 gcagtgagct ggcatcatga tgaaaatctg gtggacaggt cagcggtggc agtgtacagt
      961 tatagctgtg aaggccctga agaggaaagt gaggatgact ctcatctcga aggcagggat
     1021 cctgatattt ggcatgttgg ttttaagatc tcatgggaca tagagacacc tggtttggcg
     1081 ataccccttc accaaggaga ctgctatttc atgcttgatg atctcaatgc cacccaccaa
     1141 cactgtgttt tggccggttc acaacctcgg tttagttcca cccaccgagt ggcagagtgc
     1201 tcaacaggaa ccttggatta tattttacaa cgctgtcagt tggctctgca gaatgtctgt
     1261 gacgatgtgg acaatgatga tgtctctttg aaatcctttg agcctgcagt tttgaaacaa
     1321 ggagaagaaa ttcataatga ggtcgagttt gagtggctga ggcagttttg gtttcaaggc
     1381 aatcgataca gaaagtgcac tgactggtgg tgtcaaccca tggctcaact ggaagcactg
     1441 tggaagaaga tggagggtgt gacaaatgct gtgcttcatg aagttaaaag agaggggctc
     1501 cccgtggaac aaaggaatga aatcttgact gccatccttg cctcgctcac tgcacgccag
     1561 aacctgagga gagaatggca tgccagagtt gaatgatcca aaggacatcg ggagaagctg
     1621 tgtgaatgca gggggaaaca ttttaaaata acagcagtac atatagactc aatgacccat
     1681 gcaaggagct ggaatggatt aagatttaat ggtgacagtg gaagaaatta tcatttgaaa
     1741 agtgctccaa agaaaaggta cagttcaatg tccacacccg agttgtcttt ctaaataaaa
     1801 tataataaaa atca
//
