LOCUS       NM_173651              20879 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens fibrous sheath interacting protein 2 (FSIP2), mRNA.
ACCESSION   NM_173651
VERSION     NM_173651.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 20879)
  AUTHORS   Zheng,R., Wang,Y., Li,Y., Guo,J., Wen,Y., Jiang,C., Yang,Y. and
            Shen,Y.
  TITLE     FSIP2 plays a role in the acrosome development during
            spermiogenesis
  JOURNAL   J Med Genet 60 (3), 254-264 (2023)
   PUBMED   35654582
  REMARK    GeneRIF: FSIP2 plays a role in the acrosome development during
            spermiogenesis.
REFERENCE   2  (bases 1 to 20879)
  AUTHORS   Liu,M., Sun,Y., Li,Y., Sun,J., Yang,Y. and Shen,Y.
  TITLE     Novel mutations in FSIP2 lead to multiple morphological
            abnormalities of the sperm flagella and poor ICSI prognosis
  JOURNAL   Gene 781, 145536 (2021)
   PUBMED   33631238
  REMARK    GeneRIF: Novel mutations in FSIP2 lead to multiple morphological
            abnormalities of the sperm flagella and poor ICSI prognosis.
REFERENCE   3  (bases 1 to 20879)
  AUTHORS   Zhang,Y., Zhu,X., Qiao,X., Sun,L., Tian,Y., Yang,Y., Zhao,Y. and
            Liu,C.
  TITLE     FSIP2 can serve as a predictive biomarker for Clear Cell Renal Cell
            Carcinoma prognosis
  JOURNAL   Int J Med Sci 17 (17), 2819-2825 (2020)
   PUBMED   33162809
  REMARK    GeneRIF: FSIP2 can serve as a predictive biomarker for Clear Cell
            Renal Cell Carcinoma prognosis.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 20879)
  AUTHORS   Liu,W., Wu,H., Wang,L., Yang,X., Liu,C., He,X., Li,W., Wang,J.,
            Chen,Y., Wang,H., Gao,Y., Tang,S., Yang,S., Jin,L., Zhang,F. and
            Cao,Y.
  TITLE     Homozygous loss-of-function mutations in FSIP2 cause male
            infertility with asthenoteratospermia
  JOURNAL   J Genet Genomics 46 (1), 53-56 (2019)
   PUBMED   30745215
  REMARK    GeneRIF: Homozygous loss-of-function mutations in FSIP2 cause male
            infertility with asthenoteratospermia
REFERENCE   5  (bases 1 to 20879)
  AUTHORS   Martinez,G., Kherraf,Z.E., Zouari,R., Fourati Ben Mustapha,S.,
            Saut,A., Pernet-Gallay,K., Bertrand,A., Bidart,M.,
            Hograindleur,J.P., Amiri-Yekta,A., Kharouf,M., Karaouzene,T.,
            Thierry-Mieg,N., Dacheux-Deschamps,D., Satre,V., Bonhivers,M.,
            Toure,A., Arnoult,C., Ray,P.F. and Coutton,C.
  TITLE     Whole-exome sequencing identifies mutations in FSIP2 as a recurrent
            cause of multiple morphological abnormalities of the sperm flagella
  JOURNAL   Hum Reprod 33 (10), 1973-1984 (2018)
   PUBMED   30137358
REFERENCE   6  (bases 1 to 20879)
  AUTHORS   Litchfield,K., Summersgill,B., Yost,S., Sultana,R., Labreche,K.,
            Dudakia,D., Renwick,A., Seal,S., Al-Saadi,R., Broderick,P.,
            Turner,N.C., Houlston,R.S., Huddart,R., Shipley,J. and Turnbull,C.
  TITLE     Whole-exome sequencing reveals the mutational spectrum of
            testicular germ cell tumours
  JOURNAL   Nat Commun 6, 5973 (2015)
   PUBMED   25609015
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 20879)
  AUTHORS   Wang,K.S., Liu,X., Zhang,Q., Wu,L.Y. and Zeng,M.
  TITLE     Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C)
            loci associated with alcohol withdrawal symptoms
  JOURNAL   J Neural Transm (Vienna) 119 (4), 425-433 (2012)
   PUBMED   22072270
REFERENCE   8  (bases 1 to 20879)
  AUTHORS   Hendrickson,S.L., Lautenberger,J.A., Chinn,L.W., Malasky,M.,
            Sezgin,E., Kingsley,L.A., Goedert,J.J., Kirk,G.D., Gomperts,E.D.,
            Buchbinder,S.P., Troyer,J.L. and O'Brien,S.J.
  TITLE     Genetic variants in nuclear-encoded mitochondrial genes influence
            AIDS progression
  JOURNAL   PLoS One 5 (9), e12862 (2010)
   PUBMED   20877624
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
            Publication Status: Online-Only
REFERENCE   9  (bases 1 to 20879)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
REFERENCE   10 (bases 1 to 20879)
  AUTHORS   Brown,P.R., Miki,K., Harper,D.B. and Eddy,E.M.
  TITLE     A-kinase anchoring protein 4 binding proteins in the fibrous sheath
            of the sperm flagellum
  JOURNAL   Biol Reprod 68 (6), 2241-2248 (2003)
   PUBMED   12606363
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC007966.3 and AC008174.2.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_173651.3.
            
            Summary: This gene encodes a protein associated with the sperm
            fibrous sheath. Genes encoding most of the fibrous-sheath
            associated proteins genes are transcribed only during the
            postmeiotic period of spermatogenesis. The protein encoded by this
            gene is specific to spermatogenic cells. Copy number variation in
            this gene may be associated with testicular germ cell tumors.
            Pseudogenes associated with this gene are reported on chromosomes 2
            and X. [provided by RefSeq, Aug 2016].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence because no single transcript was available for the
            full length of the gene. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            CCDS Note: The coding region has been updated to shorten the
            N-terminus to one that is more supported by the available
            transcript and conservation data.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000424728.6/ ENSP00000401306.1
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-190               AC007966.3         10928-11117         c
            191-316             AC007966.3         10450-10575         c
            317-478             AC007966.3         6627-6788           c
            479-568             AC007966.3         5510-5599           c
            569-708             AC007966.3         4353-4492           c
            709-850             AC007966.3         3111-3252           c
            851-961             AC007966.3         2498-2608           c
            962-1082            AC008174.2         99542-99662         c
            1083-1169           AC008174.2         97106-97192         c
            1170-1285           AC008174.2         92281-92396         c
            1286-1331           AC008174.2         91367-91412         c
            1332-1438           AC008174.2         90095-90201         c
            1439-1502           AC008174.2         88819-88882         c
            1503-1560           AC008174.2         70622-70679         c
            1561-1597           AC008174.2         67096-67132         c
            1598-10481          AC008174.2         55858-64741         c
            10482-19918         AC008174.2         44251-53687         c
            19919-20416         AC008174.2         39342-39839         c
            20417-20517         AC008174.2         37913-38013         c
            20518-20564         AC008174.2         28904-28950         c
            20565-20608         AC008174.2         25185-25228         c
            20609-20678         AC008174.2         21502-21571         c
            20679-20879         AC008174.2         20094-20294         c
FEATURES             Location/Qualifiers
     source          1..20879
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q32.1"
     gene            1..20879
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /note="fibrous sheath interacting protein 2"
                     /db_xref="GeneID:401024"
                     /db_xref="HGNC:HGNC:21675"
                     /db_xref="MIM:615796"
     exon            1..190
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..20815
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /codon_start=1
                     /product="fibrous sheath-interacting protein 2"
                     /protein_id="NP_775922.3"
                     /db_xref="CCDS:CCDS54426.2"
                     /db_xref="GeneID:401024"
                     /db_xref="HGNC:HGNC:21675"
                     /db_xref="MIM:615796"
                     /translation="MELYLGACSKPAKVAVTKTVASVLAADTQQCRDGVHKTHFAGVG
                     PAQLLDLPLGVKLPVIPGSNAVFYTTNFGEKLFRPSYGFNLTDPYCRLLENQYKSLHD
                     PHLKAYYKRKDILKRLKKGGYITSNNKVVCTLRELNKYRQYLTSLKLDFERNYIKEQR
                     ILAKQLHNIPENNQIPQHCDVAQVQNWLLKEGTESIKDQERLMRHRYLDMISRKLEQL
                     ERTAEEQRLFLMDREERRQREHTRRKLTLRRKIEEEWKTKEMLLLTRMAEDVKREERI
                     EEQQHRNREESDRKKQDLLEKKMAYHLQKMQDTGFNGEDIGKNTFKYRGQDGTHASPK
                     NKKKTSEDIMLVYPAGDQNTYKETHGHTANAAHQRQNSSNNFTKKNSASVVYQADVQD
                     NGINQKRDGMVSKNSSIFDDRGGINISGQGSIISAQVSPTRNFSRVSQAFLDPSKEEK
                     ETNADWDGRPTKRSSYLCESGPQAHATDPGIFSSPVYTNMQQNLLQNCLQEKVTSEEL
                     NIIIQNVMTWVVATVTSILYPAITKYEKRLQNNTYPVSDDSILSSDSSSFCSTCSEDF
                     TYRSYTSATTKTFQAEPCAFVVDTSVRRPTTPIKPPPAHVEKTVVGKTCHIKGQSIIS
                     KHKYNKTNLLYSYPKLRSCKSDSHLLASFETGTKKSKDATTETDSLGSSLHCDKTAKA
                     MDEMKNLKNVFVNFKCYLKGETEVILESILREIMSDLTQAIPSLSSVTAEVFVEQCER
                     EKEILLSNAHIPSVASEIVENMLEKLESAVEKKCVEMFSQDLSVDIKPSLAASDELLT
                     SSNGKPLKNSMPHTLDPMCDIAEDMVHAILEKLMTLVSFKQNEFLHLKDTNKLSCQQH
                     KTDPICMFLQRAGKNKSSLESDEASLIVNEEVQNLISNIFSQSSLVAYIEEAINAILG
                     YIQTELNNERIIASEETVVLLQLLEDILFQLHQEPVNESFQKSRQPRISSPSDTKEKY
                     RLTGTRLSNSPRSGRPFPPINVPGMVLYSDDENEEIDNIVKNVLDSTFKDEKVKSQEQ
                     IPNHWFTKGNTCFECKRNIKPPTKPGSRSKAAFHDWELKTEPPSTNHEDILKKKLSSN
                     KDISTFSQDQKHQIEKASENIVTSILKEMLKDISSVPFGHLDSKTGSEASVLVSEKPQ
                     GLSHQEWIDQMFSVSEISTVAQEITDSVLNILHKASNYISNTTKSSISSSVHQISLHN
                     SDTEHIVKEAPNKYPLKTWFDSEKKMKYLSLFDVDPEKPPWLKSGKSEPKPVDDINDK
                     IIRTIFKRLKSFICPKLHMGFKSSLRSQLSKYTAKIVNIVLCAIQNELELHKENLNLR
                     EIDHTKSLTDKGFFANTDKKLESLVTSIDDDILASPLLTCIYDMLLSSENAHQRSISL
                     SSRKPKSATDSVDVQSILPNRQDKKSFHKYLATPCTHHSVNGGNHIKENAKLQVLERI
                     GETLHEMLSKLLGTHLHSQLSCSQQSREMTNKNQKMAAALQSNIQLISKAILDYILAK
                     LCGVDMDTSFASCGLKAISESLDIDNPSFASIIEKMAKSTKIISSIVSRRVQEDNKEE
                     TKSKAKPVAPVSSKTPSTKEMHPNKLKAVASDILNMVFAKLEGFANGHLEILGAINDG
                     NKKSNKIGWEYESTNISRDTHEASFLSALYMHAKKVSSAILKVIQTELNVTSSDLKTS
                     VENPPPETQILKYVVKLILDAVSSDMFNEMESEGGGIETYRYRPTYGSLPGGAESDSF
                     LEDDAYTAKKIIDERSPQREEVKTRSLKQWALEKTLNKIEVKLKEPHISPIAPIIRNI
                     LNEIFQSTLINQLNVLSLSHSNFNGMPHNVDEPTPQTSVQFMDKMMDPLLSEADITIV
                     TDNIVRTVFHKLYSAAMTERNVRENRYKTITFSANVSSHEHTYKGKSSVTALDENPCT
                     FQSRFSVADKETKVNLAEDIVQAILTNLETFATSKVKSLFYSQVNFTVPVALPIQQDH
                     STLSKALSAKDSYSDEQFSCCSVDHTKSGKTNLCQLSLSKLNTYALQVARRNLQGIKQ
                     ELDKERENPFLTHDIGISESIASQIVNALLDIISRKGKCDKNSSDKEIDLDQQKGVIE
                     KLLNETKYRKVLQLQIQDTIEGILCDIYEKTLFQNNLSFATPTLKCSIADKHSEENSE
                     MFMEGANKIIPKLSVPKSDVILISNDIVNIVLHNLSSAATLVINAKNPTSARLPLTFC
                     DTFPKIDCQQPLKGSKTERKTERFSYSRNQKSAYADDNQITVVEKEDTQKSATDSCEE
                     NANFITKTIFKRLESFATERIDSLITLAFQSKEKSFVIPELENCKQNDSIFYDSSQVE
                     SDVNVLKISATETILSQELTDFTFVGRREKLGSTIHLSQARLKTYADVIASAILKLIK
                     NDLDLEIQKIYPYQNNILFQENIIVSEIVDSMLKMLDDKRSVKEICFNSKENSNFSQL
                     ALSNEILLGHKEKERSTKQSLFTKYPLEQNQMILENKRQIIVLEEIFMRNGESKNKEK
                     GELLIAVEELLNKLYQRVREVTGHLPPLNETANFISNSKIKTSDTTQKNSFQSHINSV
                     ANDIVESVLGKMYLVVVTSLYENNKSRTEVEISDHNDSLLMKPLRFRETKQAGKISNS
                     PRYAISQAYSYVDSQNISVMENTLLPYLPLQVKKDLIQMVLNKITNFVSLPLKVSPKD
                     NPKPCFKAHLKTRSKITTLPKFTKKTHLGLSAAKAKSKTKLGPGEKTLKDSRSKTAIG
                     LSHIMSAGDAKNLLDTKLPTSELKIYAKDIIINILETIVKEFGKVKQTKALPSDQIIA
                     AGKIVNTVLQELYVTNNCNLAYPMKSSHLRLSQGNIGTGSLPKQQACFYLENVSSQLE
                     HIFPREGIFKKLFDKWQTESNDKENEKCKLLMIAENVLTEISIKAKELEYSLSLLNLP
                     PLENCESRFYNHFKGASTRAEDTKAQINMFGREIVEMLLEKLQLCFLSQIPTPDSEET
                     LSNSKEHITAKSKYGFPNKHSLSSLPIYNTKTKDQISVGSSNQIVQEIVETVLNMLES
                     FVDLQFKHISKYEFSEIVKMPIENLSSIQQKLLNKKMLPKLQPLKMFSDKSESNTINF
                     KENIQNILLRVHSFHSQLLTYAVNIISDMLAVIKNKLDNEISQMEPSSISILKENIVA
                     SEIIGTLMDQCTYFNESLIQNLSRESLFQGAENAYTVNQVELATNMKMFTSKLKEGSL
                     GINPSQVSKTGFVFCSDEDMKEKYRVSSDLPTSVRSSVEDTVKNSEPTKRPDSETMPS
                     CSTRNKVQDHRPRESNFGSFDQTMKGNSYLPEGSFLQKLLRKASDSTEAALKQVLSFI
                     EMGKGENLRVFHYENLKPVVEPNQIQTTISPLKICLAAENIVNTVLSSCGFPSQPHTN
                     ENREIMKPFFISKQSSLSEVSGGQKDNEKSLLRMQDKKINYIPEEENENLEASREDSS
                     FLQKLKKKEYPKIETVKEVEAFTFADHEMGSNEVHLIARHVTTSVVTYLKNFETTVFS
                     EEKMSVSTWSRKKYESKQFLRNIYDDSSIYQCCEHLTESVLYHLTSSISDGTKKGREK
                     EKAWEIQEATFSKIISIHSQVFESRSISIGELALCISEIIIKILFNNKIIQADIAQKM
                     VAIPTKYTYCPGIVSGGFDDLFQDLLVGVIHVLSKEIEVDYHFESNVRNKSFSMHRNN
                     SVPLCNKINRQASPRDWQFSTQQIGQLFQKNKLSYLACKLNSLVGNLKTSESKEVVNK
                     VFNIVSDLFSPDECLDTGMDSGKIQRTYFYSSNNEQPNSILTNNLQLSSKSVFLLNVV
                     CEKLIRILLEECTSTAFPDKGSVSEETSAEECQLLKMLQSVEDGKSDYRKGGMDCECL
                     QVDYMSDLLENVAEIDQDLLTSDSMLTIISHSLVKSLMDKLSHSIQQAPESLPFANKH
                     LNYRTREIQSSFIKARKSELIELGQSKSSLELRSYDSNSLTVSLNNPSVVSSKIQAPF
                     NKHCAVKSSSVSPFERQRTKEMDKVAIHNKLHQEGIYAGVYSATFLEGIISELFFNLS
                     MSLWGKNKNITVSWLNEMNTLFVNNVVNEFNNAQVTVLRNAEERLCFPPVHTETVSKI
                     VDSVYYDVLQQYELKVACGNNPVYDNASIAEQITNGILLEILDYKLPSCFKEHLIPHS
                     YYPLKPEIILQKLQSNLTEFTSLPRSSSDYSTMLSHSFLEDVIRRLLSQLIPPPITCS
                     SLGKKYLMSSDFNEMSTCIINKVMSAISKHKIWFTIYDNQYLYTGKNLQKMVDSVYCN
                     ILQMSDSLVSIQKSIVSRSPIMIDQIASFIIQEIIENHLQPFLSGEVLCHPRTPLDPV
                     STIVTQVLSEVIESHRPQKQSPLDIHLDSFVREIVARLLSKIFSPKHNTEIELKNMTQ
                     RIVNSINRHFNKAKIHILYDDKEQAFFSFNTDIVDELATSVYRNALKQHGLDLAVDKE
                     SEDSGIFVENITNLIVAAISDYLLHPLFSGDFSASTYSNSVAENIVQDILSNISKSTE
                     PSQSVPLYNTLLPYTFLEDMIRVLLSKLFSSASSLVLNRDTQKDISRVNFNDIASNLV
                     SDIRMKVSQHEIRFSKEEEETKFIYSEDDIQHLVDSVFANVVQTSGSQESAVQNITSS
                     NDILIDRIAGFIIKHICQKHLQPFVSGKSLSSSDTYFDDERRQLFYTSVYSSTFLEDV
                     ISGVLRKIFHRVVGIVQTKSIRDSEDELFEKAEELIHLITGEFSKAQVSIIDNTEERL
                     CLPPVERDVVKTIVDMVYSKVLQEYEMEVVPNKDFLNDTKTLAARITNIILAEIFDFQ
                     IHPDLIANLPFKSHSKLSANVLIQRVQYDISKSRFQRQASTMYTTMLSHSHLEKIVTQ
                     LTSQISPLNTSAEQSDTTKSDLSNTVIKLINEIMSIISKHEICIIKYGNKKQSMISAK
                     DIQSMVDSIYADLSHSNIYQSITKDKKSISDIPVSKIASFIIKEIFNHHIQSFLSEDK
                     TLLLAAVDQTYKLKAIDPKQRELSFIVNSSVFLEEVISELLCKILYAFSHNMLVTENP
                     DRVKLKLTRIVTTLVNSIVLEFTTSEILVADNFDKNLCFSERYKEMVQKIVNSVYGKV
                     LDQYKSLIQIHRVIQSDTICFGRKIYYLLLEEIYDYQVQSLVSGELESSSYSYPQADN
                     IIRNVLNIITKDSHALPPYITVLPHSLLEDMVYRLLGHVFPSTHTENELKEKKFPPDD
                     EFVEAASKLTDEIIKEISEHEIRLSMAEDNAESMQLEPIENLVDSICNNILKTSEFQA
                     EVQKDADKKGCSFLSKLAGFIMKEIMYHHLQPFLHGEESSFSDLSDYDHVSELAKSGK
                     EKTQPSLYSATFLEDIIIDLVHKFCSLLIITEDSKKNEMAELDIMGLALKLANSLIRE
                     FKKSDIKVLPNAEKMFSFPPIDKETVDKISNFVYEQFIEKCTSHDIQKGDESNIAIGM
                     IAALTQKAISAFRIQPLFSGDWSSTFFSFLNPDNITQRVQHLPQNTFTQISRCAKENQ
                     LSLPDQSYKDTSSTPDCKNMMSTLEINRGTMNRKKSFKTKDTSVKKGDIQNPVLSSIN
                     AIMKSGMINLTSGLATGVTNKKEVDENKVGICTQKHSENVSKVTSTTTVKSKDTQEPN
                     LSETFNNNEIEKKRNLIPTDKKGKDDEIYTHFSLIIDDTEYEKEVLGSDSEIGYKKKI
                     DNARESSFKKDDKLFQLSSLKSKRNLGTTTDTLEIRIRTSSNEGRRDSPTQTCRDEEH
                     HSDYEHVQNVIENIFEDVLELSSSPEPAYYSKLSYDQSPPGDNVLNVIQEISRDSAQS
                     VTTKKVSSSTNKNISAKEKEEEEREKEKVREEIKSEPSKPDDPQNQRESKPGIFPAKF
                     LEDVITEMVKQLIFSSIPETQIQDRCQNVSDKQNQAKLYDTAMKLINSLLKEFSDAQI
                     KVFRPDKGNQFPGGKVSSVPKVPPRYKEPTTDEAPSSIKIKSADKMPPMHKMMRKPSS
                     DKIPSIDKTLVNKVVHSSVCNILNDYGSQDSIWKNINSNGENLARRLTSAVINEIFQR
                     QVNLIFCDEVSVSACLPLESKDVVKKVQKLAQTASKECQTSSPYTIILPHKFLENVIS
                     ALFSKIFSTISSTKTKEPEDNLSTELNFLQMKLVSAVATEISQDKYMTIQYVETLQSD
                     DDEIIQLVVQSVYNNLLPQFGSQEIIQNCVTSGCKILSENIVDLVLREVASNQLQSYF
                     CGELTPHQCVEVENIVEKILKDVFQTTDVPLPKPSHADKLSYNIIEEIAVKFLSKLLS
                     IFPKVHKERTKSLETDMQKITSKVLNSVQEFISKSKIKLVPPTKESPTVPVADNATIE
                     NIVNSIYTSVLKHSGSYTSVFKDLMGKSNVLSDTIGFLMVNAISNSEFQPQVEEEVSN
                     SELVLEAVKIMEKVIKIIDELKSKEKSSSRKGLTLDAKLLEEVLALFLAKLIRLPSSS
                     SKDEKNLSKTELNKIASQLSKLVTAEISRSSISLIASDPEEHCLNPENTERIYQVVDS
                     VYSNILQQSGTNKEFYYDIKDTNTAFPKKVASLIIDGVSSFPLDTINSTISNADLSGE
                     LDVNRIVQKAQEHAFNVIPELEQEKLDQNLSEEESPIKIVPHVGKKPVKIDPKIISEH
                     LAVISIKTQPLEKLKQECLKRTGHSIAELRRASISGRNYSLGSPDLEKRKTERRTSLD
                     KTGRLDVKPLEAVARNSFQNIRKPDITKVELLKDVQSKNDLIVRLVAHDIDQVYLENY
                     IKEERDSDEDEVVLTQTFAKEEGIKVFEDQVKEVKKPIQSKLSPKSTLSTSSLKKFLS
                     LSKCCQTTASANIESTEAISNQVIESKETHVKRAVAELDMATPKTMPETASSSWEEKP
                     QCKKEEKNLVTEPTHYFIHRIMSSSSYNQEDLISSTGEAEDCHSDPSAKILEESSQEQ
                     KPEHGNSVKFITIFERSKDVLGSANPSKEVISETPKPDVSKQGSKMLTKMSSTLSKVF
                     SQCNTNISRSSSPAHQDEH"
     exon            191..316
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            317..478
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            479..568
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            569..708
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            709..850
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            851..961
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            962..1082
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            1083..1169
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            1170..1285
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            1286..1331
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            1332..1438
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            1439..1502
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            1503..1560
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            1561..1597
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            1598..10481
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            10482..19918
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            19919..20416
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            20417..20517
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            20518..20564
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            20565..20608
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            20609..20678
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     exon            20679..20879
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /inference="alignment:Splign:2.1.0"
     regulatory      20857..20862
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /note="hexamer: AATAAA"
     polyA_site      20879
                     /gene="FSIP2"
                     /gene_synonym="SPGF34"
                     /note="major polyA site"
ORIGIN      
        1 attcctggtc aggtccggac agagggacaa cggggtgcta gagaaggaga gcggggcggg
       61 tgaggaaggg gctgaggggg ctgtgccggc catggagctg tacctcggcg cctgctccaa
      121 gcctgccaaa gtcgccgtca ccaagacggt cgccagcgtc ctggccgcgg acacccagca
      181 gtgcagagac ggcgtgcaca aaacccactt tgcaggggtt ggaccggctc agctactgga
      241 cctacctctc ggggtcaagc tgcctgtgat cccaggaagc aatgctgtat tctatactac
      301 gaatttcggt gaaaagcttt ttcgaccttc ttatggtttt aacctgactg atccctattg
      361 tcgacttttg gaaaaccaat ataaaagcct ccatgatcca catttaaaag catactataa
      421 gcgcaaagat attttgaaga gattaaagaa aggtggctac atcaccagca ataataaagt
      481 tgtatgtacc ttgagagaat tgaataagta caggcaatat cttaccagtt taaaattaga
      541 ctttgagaga aactatataa aagaacaaag aatacttgca aaacaactac ataacatacc
      601 ggaaaacaat caaatccctc aacattgtga tgttgcacaa gtccaaaact ggttgttaaa
      661 ggagggcact gaatctatta aggaccagga gcggctgatg aggcatagat atttggatat
      721 gataagtaga aaactagaac aacttgaacg cacagcagaa gaacaacgcc tattcctaat
      781 ggatagagaa gaaagacgac agcgggaaca cacaagaaga aaacttactc ttcgtagaaa
      841 aatagaagag gaatggaaga caaaagagat gttacttctg acaaggatgg cagaagatgt
      901 taaaagagaa gagaggatag aagaacaaca gcatagaaac agagaagaga gtgacaggaa
      961 gaaacaagat cttctagaga aaaaaatggc ttatcattta caaaaaatgc aagatactgg
     1021 ctttaacgga gaagatatag gaaaaaatac atttaaatac agaggtcaag atggaacaca
     1081 tgcttctcca aagaataaaa agaagacttc tgaagatata atgttagttt atcctgctgg
     1141 agaccagaat acatataaag aaacacatgg acatacagca aatgctgctc atcagcgtca
     1201 aaatagttca aataatttta cgaaaaaaaa ctcagcttct gttgtttatc aggcagatgt
     1261 acaggataat ggtataaatc aaaagagaga tgggatggta tctaaaaact caagtatttt
     1321 cgatgataga ggaggtataa atatttcagg ccaaggttca attatttcag cgcaggtatc
     1381 acccacgaga aatttttcca gagtttcaca ggcatttttg gatccttcaa aagaagagaa
     1441 ggagacaaat gctgattggg atggaagacc aaccaagaga tcaagctatc tctgcgaatc
     1501 aggacctcag gctcatgcta cagacccggg tatattttct tctcctgttt acacaaatat
     1561 gcaacagaac ttgctgcaaa attgcttgca agaaaaagta acttctgaag aactgaatat
     1621 tataattcag aatgtaatga cctgggttgt ggctacagtg accagtatat tgtacccagc
     1681 catcacaaag tatgaaaaaa gattgcaaaa taatacatac ccagtatctg atgactccat
     1741 cctctcttca gatagttcaa gtttctgtag cacgtgcagt gaagacttta catatagaag
     1801 ctacacatct gcaacaacta aaacatttca ggcagaaccc tgtgcatttg tagttgacac
     1861 gtcagtaagg agaccaacca cacctataaa acctcctcct gcacatgtgg aaaaaacagt
     1921 tgtggggaaa acatgtcaca taaaaggaca atctataatc tctaaacata aatataataa
     1981 aaccaacttg ctatattcat accctaagct cagaagttgt aaatcagata gtcacctttt
     2041 agcatcattt gaaacaggca caaaaaaatc taaggatgct accactgaaa cagatagctt
     2101 agggagttca ttgcattgtg ataaaacagc aaaagccatg gatgaaatga agaatttaaa
     2161 aaatgttttt gttaacttta aatgttactt gaaaggggaa actgaagtga ttttagaaag
     2221 cattttgcga gaaataatgt ctgatttaac ccaggccatt ccctctctct cttctgttac
     2281 tgctgaagtt tttgttgaac aatgtgaacg tgaaaaagaa atcttgcttt ccaatgctca
     2341 tattccctca gttgcttctg agattgtgga aaatatgctt gagaagttag agtctgcagt
     2401 tgagaaaaaa tgtgttgaga tgttttcaca agatttgtca gtcgacatta aaccaagttt
     2461 agcagccagt gatgaacttc tcacatcatc taatggaaaa cctttgaaaa attcaatgcc
     2521 tcatactttg gacccaatgt gtgatattgc agaggacatg gtgcatgcca ttttagaaaa
     2581 gctaatgact cttgtttctt ttaagcaaaa tgaatttctt catcttaaag acacaaataa
     2641 gctttcctgc cagcaacata agacagaccc aatatgtatg ttccttcaaa gagctggcaa
     2701 aaataaatct agtcttgaat ctgatgaagc tagtttaatt gtcaatgaag aagtacaaaa
     2761 tttaatatca aatatttttt cccagtcttc tttggttgct tatatagagg aagcaatcaa
     2821 tgctatacta ggttatatac aaactgaact aaataatgag agaattattg catctgaaga
     2881 aaccgtagta ctccttcagc tacttgagga catccttttt cagctccatc aggaaccagt
     2941 aaatgaaagt tttcaaaaaa gtaggcaacc tagaataagt agtccttctg acaccaaaga
     3001 aaagtacaga ctcactggca ctagattatc aaatagtcct aggtctggaa gaccatttcc
     3061 acctataaat gttccaggca tggttcttta ttctgatgat gaaaatgagg aaatagacaa
     3121 tattgtaaaa aatgtgcttg attcaacttt caaagatgaa aaagtaaaat cacaagaaca
     3181 gattcctaat cattggttta caaagggaaa cacttgtttt gaatgcaaaa gaaatatcaa
     3241 accacctaca aagcctggtt ctagaagcaa agctgcattt catgattggg aattaaagac
     3301 tgagccacca tctactaatc atgaagatat tttaaagaaa aaactttctt cgaataaaga
     3361 catttcaact ttcagccaag atcaaaagca tcaaatagaa aaggcttcag aaaacatagt
     3421 cacaagtatt ttaaaggaaa tgctcaagga catatcttcc gttccttttg gtcacttaga
     3481 cagcaaaact ggcagtgaag cttcagttct tgtttcagaa aagcctcaag gactgtcaca
     3541 tcaagaatgg atagaccaga tgttttctgt ttcagaaatc agtacagtgg ctcaagaaat
     3601 aacagattct gtgttaaaca tacttcataa ggcatcaaac tacatttcca ataccactaa
     3661 aagttccatt tcatcatcag ttcatcagat ttccttacat aattctgaca ctgaacacat
     3721 agtcaaagaa gcaccaaata aatacccatt aaaaacatgg tttgacagtg aaaagaaaat
     3781 gaaatattta tctttatttg acgttgatcc tgaaaagcct ccctggttaa aatctggaaa
     3841 aagtgaacct aaacctgtag atgacattaa tgataagatc attcgtacaa tttttaaaag
     3901 actgaagtca tttatttgtc caaaattgca tatgggcttc aaatcttcat tacgatctca
     3961 acttagtaag tacacagcta aaatagtaaa cattgtttta tgtgctatcc agaatgaact
     4021 ggaacttcac aaggaaaacc taaatcttag ggagattgac cataccaaat cccttacaga
     4081 taaaggattt tttgctaata ctgataaaaa attagaatct cttgtcacga gtattgatga
     4141 tgacattttg gcgagtccat tattaacctg tatttatgat atgttgttat caagtgaaaa
     4201 tgcacatcaa agaagcattt cactctcttc tcgtaagcca aagtctgcaa ctgacagtgt
     4261 tgatgtacaa agcattttgc caaataggca agataaaaaa tcttttcaca aatatttggc
     4321 tactccttgt actcaccaca gtgtcaatgg tggaaaccat attaaagaga atgcaaaatt
     4381 gcaagtgtta gaaagaattg gggaaacact acatgaaatg ttaagcaagc tcctggggac
     4441 ccatcttcat tctcagctat cttgtagtca acaaagcaga gagatgacca ataagaatca
     4501 gaaaatggct gctgcattgc agtctaatat tcagttaatt tctaaagcaa ttttggatta
     4561 tatccttgca aaattatgtg gtgttgacat ggataccagt tttgcaagtt gtggattaaa
     4621 agctatctca gagtctcttg acattgacaa cccatcattt gcttcaatta ttgagaaaat
     4681 ggccaaatcc accaaaataa tctccagcat agtttccaga agggttcagg aggacaataa
     4741 agaagagact aaaagcaagg caaaacctgt tgctcctgtg tcttccaaaa caccaagcac
     4801 aaaagaaatg catccaaata aactaaaagc tgtagcttca gatattctta atatggtttt
     4861 tgctaaactg gaagggtttg ccaacggaca tttagaaatt ttgggtgcta ttaatgatgg
     4921 aaataagaaa agcaataaga taggctggga atatgaaagc accaatattt ccagagacac
     4981 acatgaagca tcatttctgt ctgctttata tatgcatgca aagaaggtat caagtgctat
     5041 tttgaaggtt attcaaacag aattaaatgt gacctcatca gatttgaaga caagtgtaga
     5101 aaacccacca cctgagactc aaatacttaa gtatgtagtc aagttaattt tagatgcagt
     5161 atcttccgat atgtttaatg aaatggaatc tgaaggggga ggcattgaaa cttatcgata
     5221 caggccaaca tatggaagtc ttcctggagg agctgaatca gattcatttc tagaagatga
     5281 tgcatataca gcgaaaaaaa ttattgatga gagatcccca caaagagaag aagtgaaaac
     5341 acgttctctt aaacaatggg ctctcgaaaa aaccttaaac aaaattgaag taaaactcaa
     5401 agaaccacat atatctccaa ttgctcccat tataagaaat attttgaatg aaatttttca
     5461 aagtacttta atcaatcaat taaatgtcct ttctctctcc cactctaatt ttaatggcat
     5521 gcctcacaat gttgatgagc caactcccca aacatctgtt caatttatgg ataaaatgat
     5581 ggatccttta ctttcggaag cagatataac catagtaaca gataatattg ttaggactgt
     5641 atttcacaaa ctttattcag ctgccatgac agaaagaaat gtaagggaaa ataggtataa
     5701 aactatcact ttttcagcaa atgtttcttc tcatgaacac acctataaag gaaagtcctc
     5761 tgtcacggct ttggatgaaa atccatgtac ttttcagtct agattcagcg ttgctgacaa
     5821 ggagacaaag gtaaatctag ctgaagatat tgtacaggca atattaacaa atttagaaac
     5881 ttttgctact tccaaagtaa aatctctctt ttattctcaa gtcaacttta cagttccagt
     5941 ggctttacct attcagcaag atcacagtac attgagcaaa gcattatcag ccaaagattc
     6001 atattctgat gagcaatttt cctgttgctc agtagatcat accaagtcag gaaagaccaa
     6061 cttgtgccaa ctgtctttgt ctaaattaaa tacttatgca ctacaagtgg ctagaagaaa
     6121 tttacaagga atcaaacagg aattagataa agaaagggaa aatccttttt taactcatga
     6181 cattgggatt tctgaaagta ttgcaagtca aattgttaac gcattgttag acattatatc
     6241 acgtaaaggc aaatgtgaca aaaacagttc tgacaaagag atcgatttag atcagcaaaa
     6301 aggtgttatt gaaaagctgc tcaatgagac caaatatcga aaagtacttc aacttcaaat
     6361 acaagatacc attgaaggta tcctatgtga tatttatgaa aaaaccctgt ttcagaataa
     6421 tctctcattt gccacaccca ctctgaaatg tagcatagct gataaacatt cagaagaaaa
     6481 ttctgaaatg ttcatggagg gtgcaaataa gattattcct aagctttcag ttcctaaatc
     6541 agatgtcatt ttgatatcca atgatatagt gaatattgtt cttcataatc tcagttctgc
     6601 tgccacgctt gtcataaatg caaagaatcc tacttctgca agattgcccc tgacattttg
     6661 tgatacgttt ccaaaaatag actgtcaaca gcctcttaag gggtcaaaaa ctgaaagaaa
     6721 aacagagcgt ttttcatatt caagaaatca gaaatcagct tatgctgatg ataatcagat
     6781 aactgtagta gagaaagaag acactcagaa atctgctact gactcatgtg aggaaaatgc
     6841 taacttcatt actaaaacta tttttaaacg tttggaatct tttgccacag aaagaataga
     6901 ttcattaatt acccttgctt tccaaagtaa agaaaagtca tttgttatcc cagaattgga
     6961 aaattgtaaa caaaatgaca gcatctttta tgattcaagc caagtggaat cagatgtaaa
     7021 tgtcctgaaa atatcagcaa ctgaaaccat tctcagccaa gagcttacag atttcacttt
     7081 tgttggtcgc agagaaaaac ttggatccac aattcaccta tcgcaagcta ggcttaagac
     7141 atatgctgac gtcattgcca gtgccatttt gaagcttatt aaaaatgact tagacttaga
     7201 aattcaaaag atatatccat atcaaaacaa tattttgttc caagaaaaca tcattgtgag
     7261 tgaaattgtt gacagtatgt taaagatgtt agatgataaa agatctgtaa aggaaatttg
     7321 ttttaattca aaagaaaatt ctaacttttc acaattagct ttatcaaatg aaatattgct
     7381 gggtcacaaa gagaaggaaa gaagtaccaa acaatctcta tttacaaagt atccattaga
     7441 gcaaaaccaa atgatattgg aaaacaaaag gcagataatt gttttggaag aaatatttat
     7501 gagaaatgga gaatcaaaaa acaaagaaaa aggtgaactg ctcattgcag tggaagaact
     7561 tttgaataag ttgtatcaaa gagtaaggga agtcacaggc catttgcctc cacttaatga
     7621 aactgccaac tttatatcta attctaagat taaaacatca gacacaacac agaaaaacag
     7681 ttttcaatca catattaaca gtgtagcaaa tgacatagtt gaaagtgttt tggggaaaat
     7741 gtacttggta gttgtgacat cattatatga aaataataaa agtaggacag aagttgaaat
     7801 atctgaccac aatgattcct tactaatgaa accattaagg tttagagaaa ctaaacaagc
     7861 aggaaaaata agtaattccc ctagatatgc gatatcacag gcttattctt atgtcgacag
     7921 tcaaaatatc tctgtgatgg aaaacactct tttgccatat ttaccattgc aagtgaagaa
     7981 agacttaatt caaatggttc tcaataagat cacaaatttt gtctcacttc ctttaaaggt
     8041 gagccctaag gacaacccta agccatgctt taaagcacat ttaaaaacaa gatcaaaaat
     8101 taccactttg cctaaattta caaaaaaaac acacttagga ctgagtgctg ctaaggccaa
     8161 aagcaaaacc aagttaggtc ctggagagaa gaccctaaaa gacagcagat ccaagactgc
     8221 cattgggttg tcacacatca tgtcagctgg agatgccaaa aatttactgg acacaaaatt
     8281 gcccacttca gaactaaaaa tatatgccaa ggatataata attaacatcc tagaaacaat
     8341 tgtgaaggaa tttggaaagg taaagcaaac caaagcttta ccatctgatc aaatcatagc
     8401 agcaggtaaa atagttaata cagttttgca agaattatat gttaccaata actgcaattt
     8461 ggcttacccg atgaaatcct cacatctcag actttcacag gggaatatag gcacaggatc
     8521 ccttcctaaa caacaagcat gtttttactt ggagaatgtt tcttcacagc tagagcacat
     8581 ttttcctaga gaaggtatat ttaaaaaatt gtttgacaag tggcaaacag aatcaaatga
     8641 caaggaaaat gaaaaatgta agctattgat gatagctgaa aatgttttga ctgaaatttc
     8701 aataaaagca aaagaattag aatattctct ttcactttta aatttgcccc ctcttgagaa
     8761 ttgtgaaagc aggttttata atcattttaa aggagcttct actagagccg aggatactaa
     8821 agcacaaatt aatatgtttg gaagggaaat tgttgaaatg ctacttgaaa aactacagct
     8881 atgctttctg tcccaaattc ccactccaga tagtgaagaa actctatcaa acagtaaaga
     8941 acacattact gctaaaagta aatatggttt tccaaacaag catagcctca gcagtttacc
     9001 aatctataac acaaagacaa aagaccaaat ttctgtgggc tccagcaacc aaattgttca
     9061 agagattgta gaaacggttt taaacatgtt agagtcattt gtggacttgc agtttaaaca
     9121 tatctccaaa tatgagtttt ctgaaattgt gaaaatgcct atagaaaacc tttcttctat
     9181 ccaacagaaa ctgttaaaca aaaaaatgtt gccaaaatta caaccactga aaatgttttc
     9241 tgataaatcc gagtcaaata ctattaattt caaggaaaac atacagaata tccttctacg
     9301 ggttcattca ttccattcac aattacttac atatgctgtt aatatcatca gtgacatgct
     9361 tgctgtaatt aagaacaagc tagacaacga aataagccaa atggaaccat cttcaattag
     9421 catattgaaa gagaacattg tagcaagtga gatcattggc acactaatgg accagtgtac
     9481 ttatttcaat gagtctttga tacaaaacct ttcaagagaa agtttgttcc aaggagctga
     9541 aaatgcctac actgttaatc aggttgaatt agcaactaat atgaaaatgt tcacatcaaa
     9601 gttaaaggaa ggtagtttgg ggattaatcc ttcacaagtg agtaaaactg ggtttgtgtt
     9661 ttgttcagat gaagatatga aagaaaagta cagggtttca tcagatttac ccacctctgt
     9721 cagatcctct gtagaagaca cagttaaaaa ctcagagcca acgaaaaggc ctgattcaga
     9781 aactatgcca tcgtgttcta ctagaaacaa agtacaagac cacagaccaa gggaatctaa
     9841 ctttggtagt tttgatcaga ccatgaaagg aaatagctac ctccctgaag gcagtttctt
     9901 acaaaagctg cttaggaaag caagtgactc cacagaagca gcattaaagc aagtcttgtc
     9961 attcatagaa atgggaaaag gtgaaaatct aagagtgttt cattatgaga acctaaaacc
    10021 agttgttgaa ccaaaccaaa ttcagacaac catttcccct ctcaaaatat gtttagctgc
    10081 agaaaatatt gtcaatactg tgctatccag ctgtggcttt ccaagtcaac cacacactaa
    10141 tgagaacagg gaaataatga aaccattttt catatcaaaa caaagctctt tatctgaagt
    10201 atctggaggg caaaaggata acgaaaaaag tttgcttaga atgcaggata aaaaaatcaa
    10261 ctatatacct gaggaagaaa atgaaaacct tgaagccagc cgggaagatt cttctttttt
    10321 gcaaaaattg aaaaaaaagg agtacccaaa gatagagact gtgaaggaag ttgaagcctt
    10381 tacttttgct gatcatgaaa tgggttccaa tgaagttcat ctgatagcaa gacatgtcac
    10441 cacatctgtg gtcacatatt tgaagaactt tgaaactaca gtttttagtg aggaaaagat
    10501 gtctgtttct acatggtcaa ggaaaaaata tgaatcaaaa cagttcctaa gaaacatata
    10561 cgatgattct tcaatttatc aatgttgtga acatctcact gagtcagtac tttaccattt
    10621 aacttcgagc atttctgatg gcaccaaaaa gggtagagaa aaagagaaag catgggaaat
    10681 tcaagaagca acatttagca agattatttc aattcattct caagtgtttg agagcaggtc
    10741 aatttccatt ggagaacttg ctttatgtat ttctgaaatc attattaaaa ttctttttaa
    10801 taataaaatt atacaggctg acattgcaca gaaaatggtt gccataccta caaaatacac
    10861 ttactgtcca ggaatagttt ctggtggctt tgatgacctc tttcaggatc tcttagtagg
    10921 agtgattcat gtactgtcca aagaaataga agtagattat cactttgaaa gcaatgtaag
    10981 aaacaaatca ttttctatgc atagaaataa tagtgtaccc ctttgcaaca aaatcaatag
    11041 acaggcaagc cccagagact ggcaattttc tactcaacaa attggtcaac tttttcaaaa
    11101 aaataagtta agttatcttg catgtaagtt aaacagcctg gttggtaacc taaaaacaag
    11161 tgaatccaaa gaagtagtca ataaagtttt taatattgtt tcagatttat tttcaccaga
    11221 tgaatgccta gatacgggta tggattctgg taaaatacaa agaacatatt tctactcctc
    11281 gaataatgag caacctaata gcatacttac caataaccta cagctctcct caaaatcagt
    11341 ttttcttctc aatgttgtat gtgagaaact tatcagaata cttttggaag aatgcacaag
    11401 cactgctttt cctgataaag ggtctgtttc agaggaaaca tcagcagaag aatgtcaact
    11461 tttaaaaatg cttcaaagtg tagaagatgg aaaatctgat tatcgtaagg gaggaatgga
    11521 ctgtgaatgc cttcaagtag attacatgtc agaccttttg gagaatgtgg cagaaattga
    11581 tcaagactta ttgacatcag actctatgct tactattatt tcccacagct tggttaaatc
    11641 attgatggac aaattatctc acagcataca acaagctccg gaaagtctac cttttgcaaa
    11701 taagcatttg aactacagaa caagagaaat acagtctagt ttcataaaag caagaaagtc
    11761 agaattaata gaattaggac agagtaaaag ttctttagaa ctcaggagct atgatagtaa
    11821 ttctttgaca gtatccctga ataatcccag tgtggttagc tccaaaatac aagcaccatt
    11881 taacaagcat tgtgcagtaa aatcctcttc tgtgtcacct tttgaaagac agagaacaaa
    11941 ggaaatggat aaggtagcca ttcataataa gctacatcag gaaggtatat atgctggtgt
    12001 ttattcagcc acatttttgg aaggaataat ttcagaattg ttttttaatc tctctatgtc
    12061 attgtggggc aaaaataaaa acatcactgt gtcctggctc aatgagatga atacattatt
    12121 tgtcaacaat gtagtgaatg aatttaataa tgctcaagtc actgttctac ggaatgctga
    12181 agaaaggctg tgttttccac cagttcatac agaaactgtt agcaaaattg ttgactcagt
    12241 ttattatgat gttttacagc agtatgaatt aaaagtggcc tgtggtaata atccggtata
    12301 cgacaatgcc tcaatagcag aacaaataac aaatggcata ttgttagaga ttttagacta
    12361 caaactgcca tcttgcttca aggaacatct cataccccat tcatattacc ctctcaaacc
    12421 tgaaattata ttgcaaaagc ttcaaagtaa cctaacagaa tttacttctc tacccaggtc
    12481 ttcatcagac tatagtacca tgttatcaca ttcattttta gaagatgtca taagaaggct
    12541 tttatctcag ctaattcctc cacccattac atgttcctct ttaggaaaaa aatatttaat
    12601 gagttctgat tttaatgaaa tgtccacttg tataataaat aaggttatgt cagccatttc
    12661 aaaacataaa atctggttca ctatatatga taatcaatat ctatatactg gaaaaaacct
    12721 ccaaaagatg gtggattctg tatattgtaa tattttgcaa atgtctgact ctcttgtttc
    12781 aatacaaaaa agtatagtaa gccgaagccc aattatgatt gaccaaatag ccagctttat
    12841 catccaagag attatcgaaa atcatcttca accatttttg agtggagagg ttttatgtca
    12901 tccaaggact ccactggatc cagtgtctac tattgttaca caggttctga gtgaagtgat
    12961 agagtcacac agacctcaga agcaatcacc tttagatatt caccttgatt catttgtaag
    13021 ggagattgtt gccagacttt tgtcaaagat tttcagccca aagcataaca ctgaaattga
    13081 gttgaaaaac atgacccaaa gaatagtaaa ctccataaat aggcatttca ataaagctaa
    13141 aattcacatt ctctatgatg acaaagaaca ggctttcttt tctttcaata cagatattgt
    13201 ggatgaactt gccacctcag tttatagaaa tgctttaaag cagcatgggc tagaccttgc
    13261 tgttgataaa gagtctgaag acagtggcat ttttgtggaa aatattacca atttaattgt
    13321 agcagctatt tcagattacc ttcttcatcc actgttttct ggggattttt cagcttctac
    13381 ctattctaat tcagtggctg agaatattgt tcaggacatc cttagtaaca tcagtaaatc
    13441 tactgagcca agccagagtg tacctctata taacaccttg ctgccataca catttttaga
    13501 agatatgatc agagtactat tatctaaatt attttcttct gcatctagcc tggttctaaa
    13561 cagagacacc caaaaagata tatcaagagt gaatttcaat gacattgctt caaacctagt
    13621 tagtgatatt aggatgaaag tttcccaaca tgaaattcga ttttcaaaag aggaagaaga
    13681 aaccaagttt atttattcag aagatgatat tcagcacctt gttgattcag tatttgcaaa
    13741 tgttgtgcaa acctctggtt ctcaagaatc agctgtgcaa aatatcacaa gcagtaatga
    13801 cattcttata gatagaatag caggtttcat cattaaacat atctgtcaaa aacatcttca
    13861 gccatttgtg agtggaaaat cattatcttc atcagacaca tattttgatg atgagagaag
    13921 gcagttattt tataccagtg tttactcttc aacattcttg gaagatgtaa tctctggggt
    13981 tttaagaaaa atattccaca gggtagtagg cattgtacaa acaaaatcca taagagattc
    14041 agaagatgaa ctgtttgaga aagctgaaga actcatacat ttgattacag gggaattctc
    14101 aaaagcccaa gttagcatta tagataatac tgaggaaaga ctgtgtttac ctccagtgga
    14161 gagggatgta gtcaaaacaa ttgttgacat ggtgtacagc aaagttttgc aagaatatga
    14221 aatggaagtc gtgcccaata aagattttct aaatgacaca aagacattgg ctgcaagaat
    14281 aactaatatc atcctggctg aaatttttga tttccaaatt catccagatc ttatagcaaa
    14341 tctgcctttt aaatcacatt ccaaactcag tgcaaatgtt ttaatacaaa gagttcaata
    14401 tgatataagt aaatcaagat tccaaagaca agcttcaaca atgtatacca ctatgttatc
    14461 acatagtcat ttggaaaaaa tagttactca gcttacatct cagataagtc cattgaacac
    14521 cagtgcagag cagtcagata ctactaaatc agacttaagt aatacagtga taaaactgat
    14581 aaatgaaatt atgtcaataa tttcaaaaca tgaaatatgt attattaaat atgggaataa
    14641 aaaacagagt atgatttcag caaaagatat ccagtctatg gttgattcca tttatgctga
    14701 tctttctcat tcaaatatat accagtccat tacaaaagat aaaaagagca taagtgacat
    14761 acctgtttca aaaatagcga gttttataat aaaagaaatc tttaaccatc atattcaatc
    14821 atttttatct gaagataaaa ctctcctttt ggcagcagtt gatcaaactt ataaattgaa
    14881 agcaatagat cctaaacaaa gagaattatc ttttattgtg aactcatctg tctttttgga
    14941 ggaagtaatt tctgagctct tatgcaaaat tctttatgca ttttcacata acatgttggt
    15001 tactgaaaat ccagatagag tgaaactgaa acttaccagg attgttacaa cattggtaaa
    15061 ttcaattgtt ctggagttca ccacatcaga gattttagtt gcagataact ttgataaaaa
    15121 tttgtgtttc tcagaaagat acaaagaaat ggttcaaaaa atagtcaact cagtatatgg
    15181 aaaagtatta gatcaatata aatctctgat tcaaatacat agggttatac aaagtgacac
    15241 aatatgtttt ggtaggaaaa tatattattt gctattggaa gaaatatatg attatcaagt
    15301 gcagtcatta gtttcaggag aattagagtc ttcttcttat tcgtatcccc aagctgataa
    15361 tatcatcaga aatgtgctta acataatcac aaaggatagc catgccttgc caccatatat
    15421 tactgtgttg cctcattctc ttttagaaga tatggtttac aggcttctag ggcatgtctt
    15481 cccttcaact cacactgaaa atgaactaaa agagaaaaag tttccaccgg atgatgaatt
    15541 tgtggaggca gcttcaaaat tgactgatga aattataaaa gaaatttctg aacatgagat
    15601 tcgactttcc atggcagagg ataatgcaga aagtatgcag ttagaaccta ttgaaaattt
    15661 ggtcgactcc atatgtaata atattttgaa aacatctgaa ttccaagctg aagtacaaaa
    15721 agatgcagac aaaaaaggat gctcattcct cagtaaatta gctggtttta ttatgaaaga
    15781 aatcatgtat catcatttac agccattttt acatggtgaa gaatcatctt tcagtgactt
    15841 atctgattat gaccatgtct ctgaacttgc taaatctggt aaagaaaaga cacagccttc
    15901 tctctattca gctacatttt tggaagacat aatcattgac cttgttcaca aattttgttc
    15961 tctcctcatt attactgaag attctaagaa aaatgaaatg gcagagctag atattatggg
    16021 cttggctcta aaacttgcaa attctctgat aagggaattt aagaaaagtg atattaaagt
    16081 tttaccaaat gctgaaaaaa tgttttcttt tccaccaatt gataaagaga cagttgataa
    16141 aatatccaat tttgtatatg aacagttcat agaaaaatgc acatctcatg atattcaaaa
    16201 aggtgatgaa agtaacattg ctatagggat gattgctgct ctaacccaga aggcaatatc
    16261 tgcattcagg attcaaccac ttttttcagg agactggtct tccaccttct tttcatttct
    16321 aaatccagat aatatcaccc aaagggttca acacctacca caaaacacct ttacacaaat
    16381 aagcagatgt gcaaaagaga accaactttc tttaccagat caatcatata aagatacttc
    16441 ttccacccca gattgcaaaa acatgatgag cactttggaa ataaatagag gtacaatgaa
    16501 tagaaagaaa agttttaaaa ccaaggacac atcagtgaaa aaaggtgaca tccaaaatcc
    16561 agtacttagc tctataaatg caattatgaa aagcggcatg attaacctaa catcagggtt
    16621 ggctacaggt gtgacaaata aaaaggaagt ggatgaaaat aaagtgggaa tttgtactca
    16681 aaaacatagt gagaatgtat caaaagttac ttcaactacc actgtgaaaa gtaaagatac
    16741 tcaggagcca aatttgagtg aaacatttaa taataatgaa attgagaaga aaagaaattt
    16801 aattccaaca gataaaaaag ggaaagatga tgagatatac acacattttt cattaataat
    16861 tgatgataca gaatatgaga aggaagtact tggatcagat tctgaaatag gctataaaaa
    16921 gaagattgac aatgcaaggg aaagctcatt taaaaaagat gacaagctct ttcagttatc
    16981 ctccttgaag tccaagagaa atctagggac tacaacagat actttggaaa taagaattcg
    17041 aacatcaagc aatgagggga gaagagactc tccaacacaa acgtgtaggg atgaggaaca
    17101 ccactcagat tatgaacatg ttcaaaatgt cattgaaaat atttttgaag atgttttaga
    17161 actatcttct tctccagaac cagcatatta ttcgaaactc agttatgacc aaagcccccc
    17221 aggtgataat gtattaaatg taattcaaga gattagcagg gattcggcac agtctgttac
    17281 aacaaaaaaa gtatcctcct caactaacaa aaatatctct gccaaagaaa aagaagagga
    17341 agagagagaa aaagagaaag taagagagga gattaaaagt gaacccagta aaccagatga
    17401 tcctcaaaac caacgagaaa gtaaacctgg aatttttccc gctaagtttt tagaagatgt
    17461 tattactgag atggttaaac aattgatctt ttcttctata ccagaaacac aaatacaaga
    17521 tagatgtcaa aatgttagtg ataagcaaaa tcaagccaaa ctctatgaca ctgctatgaa
    17581 actcatcaat tcactgttaa aggagttctc agatgctcaa attaaggttt tcaggccaga
    17641 taagggaaat cagttccctg ggggtaaagt gtcttcagtt cctaaagtac ctccaaggta
    17701 taaagagcca actacagatg aagcaccatc cagcattaag ataaaatctg cagataaaat
    17761 gccacctatg cataaaatga tgagaaaacc ttcttcagat aagataccat caattgacaa
    17821 aacattggtc aataaagttg ttcactcctc tgtttgtaat attttaaatg actatggatc
    17881 tcaagactct atttggaaga atataaacag taatggagaa aatttagcaa gaagactaac
    17941 tagtgcagtg ataaatgaaa ttttccaacg tcaggttaac ttgatatttt gtgatgaggt
    18001 ttcagtttca gcatgtttgc ctctggaatc taaggatgtt gttaaaaagg tccaaaagtt
    18061 ggcccaaaca gccagcaaag aatgtcaaac ttcatcacca tatacaataa tattacctca
    18121 taaatttttg gagaatgtga tttctgctct tttctccaaa attttctcaa caatatccag
    18181 cacaaaaaca aaagaacctg aggacaattt gtccacagaa ctgaatttcc ttcaaatgaa
    18241 gttagtaagt gcagttgcaa cagagatctc ccaagataaa tatatgacta tacagtatgt
    18301 agaaacctta caatctgatg atgatgaaat tattcaatta gtggttcagt ctgtttataa
    18361 taatctcttg ccacagtttg gatcacaaga gattatacaa aattgtgtaa ccagtggatg
    18421 caaaatcctt tcagaaaaca tagttgactt ggttctacga gaagtggcta gcaatcagct
    18481 gcagagctat ttttgtggag agctaactcc acatcagtgt gtggaagttg aaaacatcgt
    18541 tgaaaagatc cttaaagatg ttttccaaac tactgatgtg cccctaccta aaccttcaca
    18601 tgctgataag ctgtcttata acataataga agaaattgct gtgaaatttt tatcaaagct
    18661 tttatctata tttccaaaag tacataaaga aagaacaaaa tctctagaga ctgatatgca
    18721 aaaaataact tcaaaagtac taaattcagt ccaagaattt atctccaaaa gtaagattaa
    18781 acttgtacca cccaccaagg aatcacctac tgtgcctgta gctgataatg caactattga
    18841 aaacatagtt aattctattt ataccagtgt tttaaagcac tctggctctt atacttctgt
    18901 atttaaagat ttaatgggta aaagcaatgt cctctctgat acaataggct ttttaatggt
    18961 gaatgcaatt tcgaattctg aatttcaacc tcaagtagag gaagaagtat caaattcaga
    19021 attagttctg gaagctgtca aaattatgga aaaagtgatc aaaattattg atgaacttaa
    19081 gtctaaggaa aagtcttcat ccagaaaagg tttgacatta gatgccaaac ttttagaaga
    19141 ggtgttggcc ttgttcttgg ctaaactaat aaggttgcca agttcctcaa gcaaagatga
    19201 aaaaaactta tcaaagactg agttaaataa aattgcatct caactgtcaa aattggtaac
    19261 agctgaaatt tccagaagta gcattagtct aatagcttct gatcctgaag agcactgttt
    19321 aaatccagaa aatacagaaa ggatttatca ggttgtcgat tccgtttata gtaacatact
    19381 gcaacaatca ggaaccaaca aagaatttta ttatgatata aaagatacaa atacagcctt
    19441 tcctaaaaaa gtggctagtt taattattga tggagtttca agttttccat tagatacaat
    19501 taactcaaca atttcaaatg ctgatctctc tggagagcta gacgttaata gaattgttca
    19561 aaaggcccaa gaacatgctt ttaatgtgat tcctgaatta gagcaagaaa agttagatca
    19621 aaatttatct gaagaggaat ctccaattaa aatagttcca catgttggaa aaaaaccagt
    19681 caaaatagat ccaaaaatta tttcagaaca cttagcagtt atttctataa aaactcaacc
    19741 tcttgagaaa cttaagcagg agtgtttgaa aagaactgga catagcatag cagaactgag
    19801 aagagcatca ataagtggga gaaattactc cttaggatca cctgatttag aaaagagaaa
    19861 gacagaaaga cgtacctcat tggataagac tggaagactg gatgtaaaac ccctagaggc
    19921 cgttgctaga aattcatttc agaatataag aaagcctgat attacaaagg tggagctctt
    19981 aaaagatgtt caaagtaaaa atgatcttat tgttcgatta gtagctcatg atattgatca
    20041 agtgtatttg gaaaattaca taaaagagga acgagattct gatgaagatg aagttgtttt
    20101 aacacagact tttgcaaaag aagaaggcat caaagtattt gaagatcaag tgaaagaagt
    20161 caagaagcca atacaaagca aactttctcc taagtcaaca ctaagcacga gcagcctgaa
    20221 aaaatttttg tcactaagta aatgttgtca gaccacagcc agtgcaaata ttgaaagtac
    20281 tgaagcaatc tcaaatcagg taatagaatc caaggagaca catgttaaaa gagctgttgc
    20341 tgagcttgac atggccacac caaagacgat gcctgaaaca gcctcttcat cttgggagga
    20401 aaagccccag tgtaagaaag aagaaaagaa tcttgttact gaaccaacac attacttcat
    20461 acacagaatt atgagttcat cttcatacaa ccaagaagat ctcatttcat ctactggtga
    20521 ggctgaagat tgtcactcag acccaagtgc taaaatatta gaagaaagtt ctcaggaaca
    20581 aaagccagag catggaaaca gtgttaagtt tatcaccatc tttgaaagat ccaaggatgt
    20641 tcttggcagt gcaaatccct caaaggaagt catttcagaa actcccaagc ccgatgtctc
    20701 caaacaagga tctaaaatgc tgacaaaaat gtcttcaact ttgtcaaagg tgttttctca
    20761 atgtaacacc aatatttcca gatcttcctc accagctcac caggatgaac actgaagctt
    20821 ttgtacctga tataagtatg cttacttctt ttagaaaata aaatggtttt taaagcata
//
