LOCUS       NM_032135               3135 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens fibrous sheath CABYR binding protein (FSCB), mRNA.
ACCESSION   NM_032135
VERSION     NM_032135.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3135)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS One 7 (12), e51954 (2012)
   PUBMED   23251661
REFERENCE   2  (bases 1 to 3135)
  AUTHORS   Li,Y.F., He,W., Jha,K.N., Klotz,K., Kim,Y.H., Mandal,A., Pulido,S.,
            Digilio,L., Flickinger,C.J. and Herr,J.C.
  TITLE     FSCB, a novel protein kinase A-phosphorylated calcium-binding
            protein, is a CABYR-binding partner involved in late steps of
            fibrous sheath biogenesis
  JOURNAL   J Biol Chem 282 (47), 34104-34119 (2007)
   PUBMED   17855365
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB036759.1, BC039878.1, AL356022.3 and AL136775.1.
            
            On May 17, 2019 this sequence version replaced NM_032135.3.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC039878.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000340446.5/ ENSP00000344579.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28                DB036759.1         14-41
            29-880              BC039878.1         1-852
            881-2849            AL356022.3         43272-45240         c
            2850-3135           AL136775.1         2226-2511
FEATURES             Location/Qualifiers
     source          1..3135
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q21.2"
     gene            1..3135
                     /gene="FSCB"
                     /gene_synonym="C14orf155"
                     /note="fibrous sheath CABYR binding protein"
                     /db_xref="GeneID:84075"
                     /db_xref="HGNC:HGNC:20494"
                     /db_xref="MIM:611779"
     exon            1..3135
                     /gene="FSCB"
                     /gene_synonym="C14orf155"
                     /inference="alignment:Splign:2.1.0"
     CDS             297..2774
                     /gene="FSCB"
                     /gene_synonym="C14orf155"
                     /codon_start=1
                     /product="fibrous sheath CABYR-binding protein"
                     /protein_id="NP_115511.3"
                     /db_xref="CCDS:CCDS9679.1"
                     /db_xref="GeneID:84075"
                     /db_xref="HGNC:HGNC:20494"
                     /db_xref="MIM:611779"
                     /translation="MVGKSQQTDVIEKKKHMAIPKSSSPKATHRIGNTSGSKGSYSAK
                     AYESIRVSSELQQTWTKRKHGQEMTSKSLQTDTIVEEKKEVKLVEETVVPEEKSADVR
                     EAAIELPESVQDVEIPPNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFS
                     ESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSF
                     TQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEE
                     ATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQ
                     PPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKA
                     PIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPA
                     EEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEV
                     QSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKG
                     VSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQP
                     PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEV
                     QSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSP
                     PPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGSVVLEGEAKFEEVSKINSVLKDLS
                     NTNDGQAPTLEIESVFHIELKQRPPEL"
     regulatory      2920..2925
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FSCB"
                     /gene_synonym="C14orf155"
                     /note="hexamer: AATAAA"
     polyA_site      2943
                     /gene="FSCB"
                     /gene_synonym="C14orf155"
                     /note="major polyA site"
ORIGIN      
        1 agttataaca gagactaaag aagaaagacg cttactgaat aaggtgggat ccaacaagag
       61 tgtagtatgg aatgcaatag cttatgaatt actttttttc tgagggagct caacagaatg
      121 acacctaaga aagggaaagt ctttgacact tggtacgttt gtgatttttg gtcattactt
      181 gaaaattaat aagtttgaaa tcactactct tagaaatgga agaaagtgat gactctaatc
      241 agcctatctc agcgtgtagg caagaaattc gaaagagaag atgacccagc aaaccaatgg
      301 taggcaaatc ccagcaaact gatgtaatag agaaaaagaa acacatggcc ataccaaaat
      361 catctagccc caaagctacc catcgtattg gtaatacttc tggaagcaaa ggcagctact
      421 ctgccaaagc ctatgagtct attagagtat cttctgagct tcagcaaact tggacaaaga
      481 gaaagcatgg acaggaaatg actagtaagt ctctccagac agacaccatt gtagaagaga
      541 aaaaagaagt caagttagtt gaggaaaccg tggtacctga agaaaagtca gctgatgtta
      601 gagaagctgc tattgaattg ccagagagtg ttcaggatgt agaaattcca ccaaacatac
      661 cttcagttca actaaaaatg gacagatctc agcagaccag ccgtacagga tactggacca
      721 tgatgaacat cccccctgta gaaaaagtgg acaaggaaca acagacatac tttagtgaat
      781 cagaaatagt ggttatttcc aggccagata gttcttctac aaagtcaaag gaagatgccc
      841 tgaaacataa atcgtcggga aagatttttg ctagtgaaca ccctgaattt caaccagcaa
      901 caaacagcaa tgaagaaatt gggcagaaaa atatcagcag aacttcattt actcaggaga
      961 ctaaaaaagg tcccccggta cttttagaag atgagcttag ggaagaagta actgtacctg
     1021 ttgtacaaga aggttctgct gttaaaaaag tggcttctgc tgaaatagag cctccatcaa
     1081 cagaaaaatt cccagctaaa atacagcctc cattagttga agaggccact gctaaagcgg
     1141 agcccagacc tgctgaagag acccatgtcc aagtacagcc atcaactgaa gagactcctg
     1201 atgctgaggc agccactgca gttgcggaga attctgttaa agttcagcct ccacctgctg
     1261 aagaggcccc tttagtggag tttcctgctg aaattcagcc tccatcagct gaagagtctc
     1321 cttctgtaga gcttctggct gaaattctgc ctccatcagc tgaagagtcc ccttcagaag
     1381 agcctcctgc tgaaattctg cctccaccag ctgaaaagtc tccttcagta gagcttcttg
     1441 gtgaaattcg gtctccctca gcacaaaagg ctcccattga agtacagcct ttaccagctg
     1501 agggcgccct tgaagaggcc ccagctaaag tagagcctcc cactgttgaa gagacccttg
     1561 ctgatgttca gcctctatta cctgaagagg ctcctagaga agaggctcga gaacttcagc
     1621 tttcaacagc tatggagacc cctgcagaag aggctcctac tgaatttcag tctccattac
     1681 ctaaagagac cactgcagaa gaggcctctg ctgaaattca gcttctagca gctacggagc
     1741 ctcctgcaga tgaaactcct gccgaagctc ggtctccact atctgaggag acttctgcag
     1801 aagaggctca tgctgaagtt caatctccat tagctgaaga gaccactgca gaagaggcct
     1861 ctgctgaaat tcagcttcta gcagctatag aggctcctgc agatgaaact cctgctgaag
     1921 ctcagtctcc actatctgag gagacttctg cagaagaggc tcctgctgaa gttcagtctc
     1981 catcagctaa gggagtttct atagaagagg cccctcttga gcttcagcct ccatcaggtg
     2041 aagagaccac tgcagaagag gcctctgctg caattcagct tctagcagct acagaggctt
     2101 ctgcagaaga ggctcctgct gaagttcagc ctccaccagc tgaggaggcc cccgctgaag
     2161 ttcagcctcc accagctgag gaggcccccg ctgaagttca gcctccacca gctgaggagg
     2221 cccccgctga agttcagcct ccaccagctg aggaggcccc cgctgaagtt cagcctccac
     2281 cagctgagga ggcccccgct gaagttcagc ctccaccagc tgaggaggcc cctgctgaag
     2341 ttcagtctct accagctgag gagactccta tagaagagac ccttgctgca gtacactctc
     2401 ccccagctga tgatgtccct gcagaagagg cctccgttga caaacattcc ccaccagctg
     2461 atttgcttct gactgaggag tttcctatag gagaggcctc tgctgaagtt tcacctccac
     2521 catctgaaca aacccctgaa gatgaggctc tggtagagaa tgtgtctaca gaatttcagt
     2581 caccgcaggt ggcaggaatt ccagcagtaa aattaggatc ggttgttttg gaaggtgaag
     2641 caaaatttga agaggtttca aaaatcaatt ctgtccttaa agatttgtct aataccaatg
     2701 atggacaggc tcccactctt gaaatagaaa gtgtttttca tatagaatta aaacaacgtc
     2761 ctcctgaact gtagtcaggt tgtacctaag ctagcaatca gaagctacat ggttttggaa
     2821 gaacatactt tagaaaaggg tgggcagcgg gaagtagctt tgtcaataag gcaaattaaa
     2881 ggggacccca agacttggaa tacaggttgg aaaatgaaca ataaaaactg tagcagcata
     2941 aaattacttg tgttaatttc attcaaattt atggcatgaa aaatacctat tttgaaagta
     3001 agtttataat tgaaaaaaat tgcttaaaat atccttccta cagtaaactt gttgacacga
     3061 gtaaagttta atctgcagcc atcttttctt gtctttgcct tccctttata agtaaatata
     3121 gtttctagtg gaaaa
//
