LOCUS       NM_001080998            2094 bp    mRNA    linear   PRI 03-AUG-2024
DEFINITION  Homo sapiens FSHD region gene 2 family member B (FRG2B), mRNA.
ACCESSION   NM_001080998 XM_927564
VERSION     NM_001080998.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2094)
  AUTHORS   Rijkers,T., Deidda,G., van Koningsbruggen,S., van Geel,M.,
            Lemmers,R.J., van Deutekom,J.C., Figlewicz,D., Hewitt,J.E.,
            Padberg,G.W., Frants,R.R. and van der Maarel,S.M.
  TITLE     FRG2, an FSHD candidate gene, is transcriptionally upregulated in
            differentiating primary myoblast cultures of FSHD patients
  JOURNAL   J Med Genet 41 (11), 826-836 (2004)
   PUBMED   15520407
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY744466.1 and AL731696.4.
            
            On May 17, 2019 this sequence version replaced NM_001080998.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY744466.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000425520.2/ ENSP00000401310.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-890               AY744466.1         1-890
            891-2094            AL731696.4         11278-12481         c
FEATURES             Location/Qualifiers
     source          1..2094
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q26.3"
     gene            1..2094
                     /gene="FRG2B"
                     /note="FSHD region gene 2 family member B"
                     /db_xref="GeneID:441581"
                     /db_xref="HGNC:HGNC:33518"
     exon            1..231
                     /gene="FRG2B"
                     /inference="alignment:Splign:2.1.0"
     CDS             54..890
                     /gene="FRG2B"
                     /note="HSA10-FRG2; FSHD region gene 2 protein family
                     member B"
                     /codon_start=1
                     /product="protein FRG2-like-1"
                     /protein_id="NP_001074467.1"
                     /db_xref="CCDS:CCDS44502.1"
                     /db_xref="GeneID:441581"
                     /db_xref="HGNC:HGNC:33518"
                     /translation="MGKGNEDPDLHCSSIQCSTDQPPFQQISFTEKGSDEKKPFKEKG
                     KTAFSHSSEKHIQRQGSEPNPNKENSEETKLKAGNSTAGSEPESSSYRENCRKRKMSS
                     KDSCQDTAGNCPEKECSLSLNKKSRSSTPVHNSEIQETCDAHHRGRSRACTGRSKRHR
                     SRALGVQTPSIRKSLVTSVRAMSEAVYQDLAQVWAQQIHSPLTCEQLTLLTRLRGPLC
                     AQVQTLYSMATQAAYVFPAESWLVPATLPGPGESALDREAHPFPGQEITETVSGSDEA
                     KL"
     exon            232..306
                     /gene="FRG2B"
                     /inference="alignment:Splign:2.1.0"
     exon            307..384
                     /gene="FRG2B"
                     /inference="alignment:Splign:2.1.0"
     exon            385..2094
                     /gene="FRG2B"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacactctgc ctttggacgt gagagagagc gcacctttca cttgagcttc aacatgggaa
       61 agggaaatga agaccccgat ctccactgct cctccatcca gtgctccact gaccagcccc
      121 ctttccaaca gatctccttt acagaaaagg gctcagatga gaagaaacca ttcaaagaaa
      181 aaggcaagac cgccttctcc cattccagtg agaagcacat acaaaggcaa ggatcggagc
      241 ccaatccaaa caaggagaat tctgaggaaa ccaagctcaa ggccgggaac agcactgctg
      301 gatcagaacc agagtccagc tcatatcggg aaaactgcag gaaaagaaaa atgagttcca
      361 aggacagctg ccaagacaca gcagggaact gtccagaaaa ggagtgcagc ttgtcattga
      421 ataaaaaatc aagatcctcc actcctgtgc acaacagtga aatccaggag acctgtgatg
      481 cccaccatag gggacgttcc agggcttgca ctgggcgcag caagcggcat aggtctcggg
      541 ccctaggagt ccaaacaccg tcaattcgaa aaagcttggt gacctctgtg cgagctatgt
      601 cagaggctgt ttatcaagac ctagcccagg tgtgggcaca gcagatccat tctccactta
      661 cctgtgagca gctgacactg ctcactcggc tccgggggcc tctgtgtgcc caggtgcaga
      721 ccttgtattc catggccacc caggcagctt atgtcttccc tgctgagagc tggcttgtcc
      781 cagccacact gccaggtcct ggggaatcag ccctggatag agaagcccat cccttccctg
      841 ggcaggagat aactgagact gtcagtggat cagatgaggc taagctgtga gcaccctgac
      901 cctattcagc agagatgcag ctctgggaat gagaacaagg atctgcttct tctcagattc
      961 ttccagatga ccagcagtga caattttaga cacactgtgt taataaatga cagaacctga
     1021 agaagtcata ggaaagaaac ttgagcggta tactcagaat ggtgagagcc ctgaattttg
     1081 cagaccgcta agactataga caaattttat atttcatgtt agacatttga tgccttttgg
     1141 atgtctgatg acagtcatgc atttctatat aatcagaaaa acattagaat gtaatcgtga
     1201 atttgcatat tttagattgt agaaaagtaa atataaaatt atgtgctcct tttttgtttt
     1261 tttttttgag acagtcttgc tatgttaccc aggctggagt gcagtggcac aatcttagct
     1321 cactgcaacc tctgcttcct gggttcaaac aattctcatg cctcagcctc ccaagcagct
     1381 gggactacag gcatgtactg ctatgcctgg ctaatttttt ttttcctgta ttgttagtag
     1441 agacagagtt ttgtcacttt ggccaggttg gcctcgaact caggtgatct gccagcctcc
     1501 gcctcccaac gtgctgggat tacaggcatg agccgcctta ccaagaaatt gcttctcttt
     1561 taatccagaa aaggttgtag gctctcactc ttccagcctg aacccatgga gtactaatat
     1621 ccacaaacca ttaatagcac tccctgtggg aaaatgtcta tatattttgt ttgatataat
     1681 tatagtaaaa ttactatgca agctgtttac ttttaatatt tctacataaa atttaagtca
     1741 agatatagta aatggtaaat gattgtactt atttattgac ctgcctcatg tttcatttca
     1801 ttttaaacat cctaaattta tattttatta tattttatac atttcaattg attgtactat
     1861 attgcaggat atggagattt catcacgtac tacaatacag tgtattttgt tatatttgac
     1921 gtatattcta cttgtatttt gtactgagat catacactat ttcattatct aagtgtatta
     1981 attgtttggt tgctttataa ttttcatttt atgtaatgaa ataaacaatg ttgtttggaa
     2041 ttttaaattt ctttcatatg gaatttgtat ttaataaaaa tgtgaaaaag agaa
//
