LOCUS       XM_047422858            4714 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens FRAS1 related extracellular matrix 1
            (FREM1), transcript variant X26, mRNA.
ACCESSION   XM_047422858
VERSION     XM_047422858.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000009.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4714
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
     gene            1..4714
                     /gene="FREM1"
                     /gene_synonym="BNAR; C9orf143; C9orf145; C9orf154; MOTA;
                     TILRR; TRIGNO2"
                     /note="FRAS1 related extracellular matrix 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 EST, 121 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 29 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:158326"
                     /db_xref="HGNC:HGNC:23399"
                     /db_xref="MIM:608944"
     CDS             542..4555
                     /gene="FREM1"
                     /gene_synonym="BNAR; C9orf143; C9orf145; C9orf154; MOTA;
                     TILRR; TRIGNO2"
                     /codon_start=1
                     /product="FRAS1-related extracellular matrix protein 1
                     isoform X17"
                     /protein_id="XP_047278814.1"
                     /db_xref="GeneID:158326"
                     /db_xref="HGNC:HGNC:23399"
                     /db_xref="MIM:608944"
                     /translation="MNSLSWGAANAVLLLLLLAWASPTFISINRGVRVMKGHSAFLSG
                     DDLKFAIPKEKDACKVEVVMNEPITQRVGKLTPQVFDCHFLPNEVKYVHNGCPILDED
                     TVKLRLYRFTERDTFIETFILWVYLLEPDCNIIHMSNNVLEVPEFNGLSQAIDKNLLR
                     FDYDRMASLECTVSLDTARTRLPAHGQMVLGEPRPEEPRGDQPHSFFPESQLRAKLKC
                     PGGSCTPGLKKIGSLKVSCEEFLLMGLRYQHLDPPSPNIDYISIQLDLTDTRSKIVYK
                     SESAWLPVYIRAGIPNQIPKAAFMAVFILEVDQFILTSLTTSVLDCEEDETPKPLLVF
                     NITKAPLQGYVTHLLDHTRPISSFTWKDLSDMQIAYQPPNSSHSERRHDEVELEVYDF
                     FFERSAPMTVHISIRTADTNAPRVSWNTGLSLLEGQSRAITWEQFQVVDNDDIGAVRL
                     VTVGGLQHGWLTLRGGKGFLFTVADLQAGVVRYHHDDSDSTKDFVVFRIFDGHHSIRH
                     KFPINVLPKDDSPPFLITNVVIELEEGQTILIQGSMLRASDVDASDDYIFFNITKPPQ
                     AGEIMKKPGPGLIGYPVHGFLQRDLFNGIIYYRHFGGEIFEDSFQFVLWDSHEPPNLS
                     VPQVATIHITPVDDQLPKEAPGVSRHLVVKETEVAYITKKQLHFIDSESYDRELVYTI
                     TTPPFFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPPMQDI
                     GPHCRDVQFTFSVSNQHGGTLHGICFNITILPVDNQVPEAFTNPLKVTEGGQSIISTE
                     HILISDADTKLDNIDLSLRELPLHGRVELNGFPLNSGGTFSWGDLHTLKVRYQHDGTE
                     VLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMNCSEGGEVVITSEYI
                     FATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMP
                     CFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIG
                     PVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSVGFEKSNIG
                     ISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTND
                     EAPDFVVQNITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHGLLIDRGFSKD
                     FSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKILK
                     TISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQ
                     NGQLQLKGGTGFLSPLA"
ORIGIN      
        1 agtacaaaac tagtagtgag aaaggaagct gggaagagac tgggaagagg caaccgacct
       61 cattaacaaa agctcagttt tgtccctgcg gacccaacca gcagaaggca cggggctagc
      121 ggtggctgtc cgccagggag gtcgggctct gtgtaaacag tagaaggcat ctttatcatg
      181 cccttctcac agggagtcct gaggcttggc gctcaggaag tttgcaaagc tgcagcagct
      241 gccttggaga agaccagcaa agaaagtgga gtgtgattag aaaagcactt gggaagccca
      301 ttaatcttgc cggcgttgtc aggagtgatc agcgagtttt attaaaagcc ctgggattgc
      361 ctgaaaggcc cccttgtctg actttgaaat gaaaggggca tgttaagatc tcggggcaca
      421 ttgtcaggac ccctcaccct gccccttgga ctatgagctg accctccagg aggaagcaca
      481 gaagccctcc tttgttaaag ggatttcgcc ggtggacaga gaagagttgg gccctgtcag
      541 catgaactct ctgagttggg gggctgcgaa tgccgtgctg ctgctgctcc tcctggcctg
      601 ggccagcccc accttcatca gcatcaaccg cggggtgagg gtgatgaagg gccactctgc
      661 cttcctgtca ggagatgacc tgaagtttgc catccctaaa gagaaagatg cctgcaaagt
      721 ggaagttgtg atgaatgagc caataaccca gagggttggg aaactcactc cacaggtctt
      781 tgactgccat ttccttccca acgaagtcaa gtatgttcac aatggttgtc caattcttga
      841 tgaagacaca gtgaagctca gactttacag atttactgaa agagatacct tcatagaaac
      901 ttttatcctg tgggtctatc tcctggaacc agactgtaac atcatccata tgagtaacaa
      961 tgtgctggag gtgcctgaat tcaatggctt gtcccaagcg attgataaaa atctgctcag
     1021 attcgattat gataggatgg ctagcctgga atgtaccgtc agcctggaca ctgcgagaac
     1081 tcggctgcca gcccatggcc agatggttct cggggagcct cgaccagaag aacctcgtgg
     1141 agatcagcca cacagttttt tcccagagtc ccaactgaga gcaaaactga agtgtccagg
     1201 tgggagctgt accccaggat taaagaaaat aggaagcctc aaagtgagct gtgaggagtt
     1261 cctgctgatg ggccttcgtt atcagcatct ggatccccct tcacccaaca ttgattatat
     1321 ctccatccaa ctggacctca cagataccag gagcaaaatt gtgtacaagt cagagagtgc
     1381 gtggctgcct gtctatatca gagctggaat tccgaatcag attccaaagg ctgcattcat
     1441 ggccgtgttt attctggaag tggatcagtt catcctgacc tccttgacta catcagttct
     1501 ggactgtgaa gaagatgaga cccctaaacc cttgctggtg ttcaacatta ctaaagcccc
     1561 gctccagggc tatgtgactc acctgttgga tcacaccaga ccaatctcct cattcacctg
     1621 gaaagatctc agtgacatgc agatcgccta tcagccacca aacagcagcc attctgagag
     1681 gagacatgat gaggtagaat tggaggtata cgacttcttc tttgaaagga gtgcacctat
     1741 gacagtccac atctccatca gaacagcaga tacaaatgcc ccccgtgtat cctggaatac
     1801 aggtctgagt ctccttgagg ggcagtctcg agccatcact tgggaacagt ttcaggttgt
     1861 cgacaatgac gacattggtg ctgtccggct agtcaccgtt ggtggcctgc agcatggatg
     1921 gctgacttta agagggggga aagggtttct cttcaccgtg gctgacctcc aggctggagt
     1981 tgttcgctat catcatgatg acagcgactc caccaaagac ttcgtggtct tccggatatt
     2041 tgatggccat cacagcatcc gtcacaaatt ccccatcaac gtcttgccca aagatgatag
     2101 tcccccgttc ctcataacca atgttgtgat tgaactggag gaggggcaga ccatcctgat
     2161 ccagggatcc atgctgcgag cttcagatgt ggacgccagt gatgactaca tcttcttcaa
     2221 tatcacaaag cctccacagg ctggggagat catgaagaag ccagggccag gactgatagg
     2281 ctatcctgtc catggcttcc ttcagaggga tttgtttaat ggaatcattt attatcgtca
     2341 ttttggtgga gaaatctttg aagattcttt tcaatttgtc ctgtgggaca gccatgaacc
     2401 tccaaatctt tcagtgccac aggtggcaac aatccatata actccagtgg atgaccagct
     2461 tccaaaagag gctcctggag tttctcggca tttggttgtc aaggaaactg aggtggccta
     2521 tataactaag aaacagctac attttataga ttcagaatca tatgacaggg agctggtcta
     2581 cacaataact actcctccat ttttctcctt cagccacaga cacttggatg ctgggaaatt
     2641 atttatggtg gacagcatac caaaagtagt taagaatcct acggccctgg agctgaggtc
     2701 attcactcag catgctgtga actatatgaa agtggcctac atgcccccca tgcaagacat
     2761 tggtccccat tgcagagatg tccagttcac attttctgtc agtaaccaac atggcggtac
     2821 tttgcatggg atctgcttta acattacaat cctcccagtg gacaatcaag ttcctgaggc
     2881 gttcaccaac cctctgaaag tgactgaggg aggtcaaagc atcatcagca cagagcacat
     2941 tctaatttct gatgcagata ccaagctgga caatattgac ctctccctgc gggaattgcc
     3001 tctgcacgga agggtggagc tgaatggatt tcctctaaat tcagggggca cattttcttg
     3061 gggcgatctc cataccttaa aagttaggta tcaacatgat ggaactgaag ttcttcagga
     3121 tgacctactc ttggaggtca ccgatggcac aaattcagca gaatttgtac tacatgttga
     3181 ggtattccct gtcaacgatg agccaccagt cttaaaggct gacctcatgc ctgtcatgaa
     3241 ttgctcagag ggaggagagg tggtcatcac ctctgaatac atttttgcta ctgatgtgga
     3301 cagcgataac ttgaagttga tgtttgtgat tgctcgcgaa cctcagcatg gggtggtgag
     3361 gagagctgga gtcacagtgg atcagttctc tcagagagat gttatctcag aggccgtgac
     3421 atacaaacac acaggtggcg agattggcct gatgccttgt tttgacacca ttacattggt
     3481 ggtttcggat ggagaggctg gcccttttgt gaatggctgt tgctacaatg gacccaatcc
     3541 atctgttcca cttcatgcgt cctttccagt gtatgatctc aacatcacgg tatacccagt
     3601 agacaaccag ccaccttcca ttgcaatagg tcccgtgttt gttgtagatg agggctgctc
     3661 aacagccctt actgttaacc atttgtccgc cactgaccct gacactgcag cagatgactt
     3721 ggaatttgtt ttggtttctc ctcctcagtt tggctacctc gaaaatatac tcccttctgt
     3781 gggttttgaa aaaagcaata ttggcataag tatagattca tttcagtgga aagacatgaa
     3841 cgcttttcac attaactatg tgcagtccag gcatctgagg atagaaccaa ctgccgacca
     3901 gttcacggtg tacgtcacag atgggaagca tcactccttg gagataccat tttctattat
     3961 aatcaacccc acaaatgatg aagctcctga ctttgtagtg cagaatatta ctgtgtgtga
     4021 gggtcagatg aaagagctgg actcttccat catcagcgct gtggacctgg acattcccca
     4081 ggatgccctg ctgttcagca tcactcaaaa gccacgccat ggcctcctca tcgatagggg
     4141 gtttagcaaa gacttctctg agaataagca gccagccaac cctcaccaga aacatgcacc
     4201 tgttcacagc ttttccatgg aactcctcaa gactggaatg aggttgacgt acatgcatga
     4261 tgactcagag agccttgctg atgattttac aatccaattg tcagatggga aacataagat
     4321 acttaaaacc atttcagtag aggtcatccc agttaatgat gaaaaaccaa tgctgagcaa
     4381 gaaggctgaa attgcaatga atatgggtga aactcgtatt atttccagtg ctattctttc
     4441 agccatagat gaagactcac ccagggagaa gatttactat gtatttgaaa ggcttcccca
     4501 aaatgggcaa cttcagctta agggagggac tgggttcctc tctcccctgg catgaaatgc
     4561 actcaggagg aagtggatct gaacttgctg agatacacac acaccggggc aatggattcc
     4621 cagaatcaag atagcttcac cttctacctt tgggatggca acaacaggtc ccctgctctt
     4681 gactgtcaaa tcaccatcaa ggacatggaa aaag
//
