LOCUS       NM_001112808            3294 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens FPGT-TNNI3K readthrough (FPGT-TNNI3K), transcript
            variant 1, mRNA.
ACCESSION   NM_001112808
VERSION     NM_001112808.3
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3294)
  AUTHORS   Perry,J.R., Day,F., Elks,C.E., Sulem,P., Thompson,D.J.,
            Ferreira,T., He,C., Chasman,D.I., Esko,T., Thorleifsson,G.,
            Albrecht,E., Ang,W.Q., Corre,T., Cousminer,D.L., Feenstra,B.,
            Franceschini,N., Ganna,A., Johnson,A.D., Kjellqvist,S.,
            Lunetta,K.L., McMahon,G., Nolte,I.M., Paternoster,L., Porcu,E.,
            Smith,A.V., Stolk,L., Teumer,A., Tsernikova,N., Tikkanen,E.,
            Ulivi,S., Wagner,E.K., Amin,N., Bierut,L.J., Byrne,E.M.,
            Hottenga,J.J., Koller,D.L., Mangino,M., Pers,T.H.,
            Yerges-Armstrong,L.M., Zhao,J.H., Andrulis,I.L., Anton-Culver,H.,
            Atsma,F., Bandinelli,S., Beckmann,M.W., Benitez,J., Blomqvist,C.,
            Bojesen,S.E., Bolla,M.K., Bonanni,B., Brauch,H., Brenner,H.,
            Buring,J.E., Chang-Claude,J., Chanock,S., Chen,J.,
            Chenevix-Trench,G., Collee,J.M., Couch,F.J., Couper,D.,
            Coveillo,A.D., Cox,A., Czene,K., D'adamo,A.P., Smith,G.D., De
            Vivo,I., Demerath,E.W., Dennis,J., Devilee,P., Dieffenbach,A.K.,
            Dunning,A.M., Eiriksdottir,G., Eriksson,J.G., Fasching,P.A.,
            Ferrucci,L., Flesch-Janys,D., Flyger,H., Foroud,T., Franke,L.,
            Garcia,M.E., Garcia-Closas,M., Geller,F., de Geus,E.E., Giles,G.G.,
            Gudbjartsson,D.F., Gudnason,V., Guenel,P., Guo,S., Hall,P.,
            Hamann,U., Haring,R., Hartman,C.A., Heath,A.C., Hofman,A.,
            Hooning,M.J., Hopper,J.L., Hu,F.B., Hunter,D.J., Karasik,D.,
            Kiel,D.P., Knight,J.A., Kosma,V.M., Kutalik,Z., Lai,S.,
            Lambrechts,D., Lindblom,A., Magi,R., Magnusson,P.K., Mannermaa,A.,
            Martin,N.G., Masson,G., McArdle,P.F., McArdle,W.L., Melbye,M.,
            Michailidou,K., Mihailov,E., Milani,L., Milne,R.L., Nevanlinna,H.,
            Neven,P., Nohr,E.A., Oldehinkel,A.J., Oostra,B.A., Palotie,A.,
            Peacock,M., Pedersen,N.L., Peterlongo,P., Peto,J., Pharoah,P.D.,
            Postma,D.S., Pouta,A., Pylkas,K., Radice,P., Ring,S.,
            Rivadeneira,F., Robino,A., Rose,L.M., Rudolph,A., Salomaa,V.,
            Sanna,S., Schlessinger,D., Schmidt,M.K., Southey,M.C., Sovio,U.,
            Stampfer,M.J., Stockl,D., Storniolo,A.M., Timpson,N.J., Tyrer,J.,
            Visser,J.A., Vollenweider,P., Volzke,H., Waeber,G.,
            Waldenberger,M., Wallaschofski,H., Wang,Q., Willemsen,G.,
            Winqvist,R., Wolffenbuttel,B.H., Wright,M.J., Boomsma,D.I.,
            Econs,M.J., Khaw,K.T., Loos,R.J., McCarthy,M.I., Montgomery,G.W.,
            Rice,J.P., Streeten,E.A., Thorsteinsdottir,U., van Duijn,C.M.,
            Alizadeh,B.Z., Bergmann,S., Boerwinkle,E., Boyd,H.A., Crisponi,L.,
            Gasparini,P., Gieger,C., Harris,T.B., Ingelsson,E., Jarvelin,M.R.,
            Kraft,P., Lawlor,D., Metspalu,A., Pennell,C.E., Ridker,P.M.,
            Snieder,H., Sorensen,T.I., Spector,T.D., Strachan,D.P.,
            Uitterlinden,A.G., Wareham,N.J., Widen,E., Zygmunt,M., Murray,A.,
            Easton,D.F., Stefansson,K., Murabito,J.M. and Ong,K.K.
  CONSRTM   Australian Ovarian Cancer Study; GENICA Network; kConFab; LifeLines
            Cohort Study; InterAct Consortium; Early Growth Genetics (EGG)
            Consortium
  TITLE     Parent-of-origin-specific allelic associations among 106 genomic
            loci for age at menarche
  JOURNAL   Nature 514 (7520), 92-97 (2014)
   PUBMED   25231870
REFERENCE   2  (bases 1 to 3294)
  AUTHORS   Graff,M., Ngwa,J.S., Workalemahu,T., Homuth,G., Schipf,S.,
            Teumer,A., Volzke,H., Wallaschofski,H., Abecasis,G.R., Edward,L.,
            Francesco,C., Sanna,S., Scheet,P., Schlessinger,D., Sidore,C.,
            Xiao,X., Wang,Z., Chanock,S.J., Jacobs,K.B., Hayes,R.B., Hu,F., Van
            Dam,R.M., Crout,R.J., Marazita,M.L., Shaffer,J.R., Atwood,L.D.,
            Fox,C.S., Heard-Costa,N.L., White,C., Choh,A.C., Czerwinski,S.A.,
            Demerath,E.W., Dyer,T.D., Towne,B., Amin,N., Oostra,B.A., Van
            Duijn,C.M., Zillikens,M.C., Esko,T., Nelis,M., Nikopensius,T.,
            Metspalu,A., Strachan,D.P., Monda,K., Qi,L., North,K.E.,
            Cupples,L.A., Gordon-Larsen,P. and Berndt,S.I.
  CONSRTM   GIANT Consortium
  TITLE     Genome-wide analysis of BMI in adolescents and young adults reveals
            additional insight into the effects of genetic loci over the life
            course
  JOURNAL   Hum Mol Genet 22 (17), 3597-3607 (2013)
   PUBMED   23669352
REFERENCE   3  (bases 1 to 3294)
  AUTHORS   Cousminer,D.L., Berry,D.J., Timpson,N.J., Ang,W., Thiering,E.,
            Byrne,E.M., Taal,H.R., Huikari,V., Bradfield,J.P., Kerkhof,M.,
            Groen-Blokhuis,M.M., Kreiner-Moller,E., Marinelli,M., Holst,C.,
            Leinonen,J.T., Perry,J.R., Surakka,I., Pietilainen,O., Kettunen,J.,
            Anttila,V., Kaakinen,M., Sovio,U., Pouta,A., Das,S., Lagou,V.,
            Power,C., Prokopenko,I., Evans,D.M., Kemp,J.P., St Pourcain,B.,
            Ring,S., Palotie,A., Kajantie,E., Osmond,C., Lehtimaki,T.,
            Viikari,J.S., Kahonen,M., Warrington,N.M., Lye,S.J., Palmer,L.J.,
            Tiesler,C.M., Flexeder,C., Montgomery,G.W., Medland,S.E.,
            Hofman,A., Hakonarson,H., Guxens,M., Bartels,M., Salomaa,V.,
            Murabito,J.M., Kaprio,J., Sorensen,T.I., Ballester,F., Bisgaard,H.,
            Boomsma,D.I., Koppelman,G.H., Grant,S.F., Jaddoe,V.W., Martin,N.G.,
            Heinrich,J., Pennell,C.E., Raitakari,O.T., Eriksson,J.G.,
            Smith,G.D., Hypponen,E., Jarvelin,M.R., McCarthy,M.I., Ripatti,S.
            and Widen,E.
  CONSRTM   ReproGen Consortium; Early Growth Genetics (EGG) Consortium
  TITLE     Genome-wide association and longitudinal analyses reveal genetic
            loci linking pubertal height growth, pubertal timing and childhood
            adiposity
  JOURNAL   Hum Mol Genet 22 (13), 2735-2747 (2013)
   PUBMED   23449627
REFERENCE   4  (bases 1 to 3294)
  AUTHORS   Berndt,S.I., Gustafsson,S., Magi,R., Ganna,A., Wheeler,E.,
            Feitosa,M.F., Justice,A.E., Monda,K.L., Croteau-Chonka,D.C.,
            Day,F.R., Esko,T., Fall,T., Ferreira,T., Gentilini,D.,
            Jackson,A.U., Luan,J., Randall,J.C., Vedantam,S., Willer,C.J.,
            Winkler,T.W., Wood,A.R., Workalemahu,T., Hu,Y.J., Lee,S.H.,
            Liang,L., Lin,D.Y., Min,J.L., Neale,B.M., Thorleifsson,G., Yang,J.,
            Albrecht,E., Amin,N., Bragg-Gresham,J.L., Cadby,G., den Heijer,M.,
            Eklund,N., Fischer,K., Goel,A., Hottenga,J.J., Huffman,J.E.,
            Jarick,I., Johansson,A., Johnson,T., Kanoni,S., Kleber,M.E.,
            Konig,I.R., Kristiansson,K., Kutalik,Z., Lamina,C., Lecoeur,C.,
            Li,G., Mangino,M., McArdle,W.L., Medina-Gomez,C.,
            Muller-Nurasyid,M., Ngwa,J.S., Nolte,I.M., Paternoster,L.,
            Pechlivanis,S., Perola,M., Peters,M.J., Preuss,M., Rose,L.M.,
            Shi,J., Shungin,D., Smith,A.V., Strawbridge,R.J., Surakka,I.,
            Teumer,A., Trip,M.D., Tyrer,J., Van Vliet-Ostaptchouk,J.V.,
            Vandenput,L., Waite,L.L., Zhao,J.H., Absher,D., Asselbergs,F.W.,
            Atalay,M., Attwood,A.P., Balmforth,A.J., Basart,H., Beilby,J.,
            Bonnycastle,L.L., Brambilla,P., Bruinenberg,M., Campbell,H.,
            Chasman,D.I., Chines,P.S., Collins,F.S., Connell,J.M.,
            Cookson,W.O., de Faire,U., de Vegt,F., Dei,M., Dimitriou,M.,
            Edkins,S., Estrada,K., Evans,D.M., Farrall,M., Ferrario,M.M.,
            Ferrieres,J., Franke,L., Frau,F., Gejman,P.V., Grallert,H.,
            Gronberg,H., Gudnason,V., Hall,A.S., Hall,P., Hartikainen,A.L.,
            Hayward,C., Heard-Costa,N.L., Heath,A.C., Hebebrand,J., Homuth,G.,
            Hu,F.B., Hunt,S.E., Hypponen,E., Iribarren,C., Jacobs,K.B.,
            Jansson,J.O., Jula,A., Kahonen,M., Kathiresan,S., Kee,F.,
            Khaw,K.T., Kivimaki,M., Koenig,W., Kraja,A.T., Kumari,M.,
            Kuulasmaa,K., Kuusisto,J., Laitinen,J.H., Lakka,T.A.,
            Langenberg,C., Launer,L.J., Lind,L., Lindstrom,J., Liu,J.,
            Liuzzi,A., Lokki,M.L., Lorentzon,M., Madden,P.A., Magnusson,P.K.,
            Manunta,P., Marek,D., Marz,W., Mateo Leach,I., McKnight,B.,
            Medland,S.E., Mihailov,E., Milani,L., Montgomery,G.W., Mooser,V.,
            Muhleisen,T.W., Munroe,P.B., Musk,A.W., Narisu,N., Navis,G.,
            Nicholson,G., Nohr,E.A., Ong,K.K., Oostra,B.A., Palmer,C.N.,
            Palotie,A., Peden,J.F., Pedersen,N., Peters,A., Polasek,O.,
            Pouta,A., Pramstaller,P.P., Prokopenko,I., Putter,C.,
            Radhakrishnan,A., Raitakari,O., Rendon,A., Rivadeneira,F.,
            Rudan,I., Saaristo,T.E., Sambrook,J.G., Sanders,A.R., Sanna,S.,
            Saramies,J., Schipf,S., Schreiber,S., Schunkert,H., Shin,S.Y.,
            Signorini,S., Sinisalo,J., Skrobek,B., Soranzo,N., Stancakova,A.,
            Stark,K., Stephens,J.C., Stirrups,K., Stolk,R.P., Stumvoll,M.,
            Swift,A.J., Theodoraki,E.V., Thorand,B., Tregouet,D.A., Tremoli,E.,
            Van der Klauw,M.M., van Meurs,J.B., Vermeulen,S.H., Viikari,J.,
            Virtamo,J., Vitart,V., Waeber,G., Wang,Z., Widen,E., Wild,S.H.,
            Willemsen,G., Winkelmann,B.R., Witteman,J.C., Wolffenbuttel,B.H.,
            Wong,A., Wright,A.F., Zillikens,M.C., Amouyel,P., Boehm,B.O.,
            Boerwinkle,E., Boomsma,D.I., Caulfield,M.J., Chanock,S.J.,
            Cupples,L.A., Cusi,D., Dedoussis,G.V., Erdmann,J., Eriksson,J.G.,
            Franks,P.W., Froguel,P., Gieger,C., Gyllensten,U., Hamsten,A.,
            Harris,T.B., Hengstenberg,C., Hicks,A.A., Hingorani,A., Hinney,A.,
            Hofman,A., Hovingh,K.G., Hveem,K., Illig,T., Jarvelin,M.R.,
            Jockel,K.H., Keinanen-Kiukaanniemi,S.M., Kiemeney,L.A., Kuh,D.,
            Laakso,M., Lehtimaki,T., Levinson,D.F., Martin,N.G., Metspalu,A.,
            Morris,A.D., Nieminen,M.S., Njolstad,I., Ohlsson,C.,
            Oldehinkel,A.J., Ouwehand,W.H., Palmer,L.J., Penninx,B., Power,C.,
            Province,M.A., Psaty,B.M., Qi,L., Rauramaa,R., Ridker,P.M.,
            Ripatti,S., Salomaa,V., Samani,N.J., Snieder,H., Sorensen,T.I.,
            Spector,T.D., Stefansson,K., Tonjes,A., Tuomilehto,J.,
            Uitterlinden,A.G., Uusitupa,M., van der Harst,P., Vollenweider,P.,
            Wallaschofski,H., Wareham,N.J., Watkins,H., Wichmann,H.E.,
            Wilson,J.F., Abecasis,G.R., Assimes,T.L., Barroso,I., Boehnke,M.,
            Borecki,I.B., Deloukas,P., Fox,C.S., Frayling,T., Groop,L.C.,
            Haritunian,T., Heid,I.M., Hunter,D., Kaplan,R.C., Karpe,F.,
            Moffatt,M.F., Mohlke,K.L., O'Connell,J.R., Pawitan,Y., Schadt,E.E.,
            Schlessinger,D., Steinthorsdottir,V., Strachan,D.P.,
            Thorsteinsdottir,U., van Duijn,C.M., Visscher,P.M., Di Blasio,A.M.,
            Hirschhorn,J.N., Lindgren,C.M., Morris,A.P., Meyre,D., Scherag,A.,
            McCarthy,M.I., Speliotes,E.K., North,K.E., Loos,R.J. and
            Ingelsson,E.
  TITLE     Genome-wide meta-analysis identifies 11 new loci for anthropometric
            traits and provides insights into genetic architecture
  JOURNAL   Nat Genet 45 (5), 501-512 (2013)
   PUBMED   23563607
REFERENCE   5  (bases 1 to 3294)
  AUTHORS   Speliotes,E.K., Willer,C.J., Berndt,S.I., Monda,K.L.,
            Thorleifsson,G., Jackson,A.U., Lango Allen,H., Lindgren,C.M.,
            Luan,J., Magi,R., Randall,J.C., Vedantam,S., Winkler,T.W., Qi,L.,
            Workalemahu,T., Heid,I.M., Steinthorsdottir,V., Stringham,H.M.,
            Weedon,M.N., Wheeler,E., Wood,A.R., Ferreira,T., Weyant,R.J.,
            Segre,A.V., Estrada,K., Liang,L., Nemesh,J., Park,J.H.,
            Gustafsson,S., Kilpelainen,T.O., Yang,J., Bouatia-Naji,N., Esko,T.,
            Feitosa,M.F., Kutalik,Z., Mangino,M., Raychaudhuri,S., Scherag,A.,
            Smith,A.V., Welch,R., Zhao,J.H., Aben,K.K., Absher,D.M., Amin,N.,
            Dixon,A.L., Fisher,E., Glazer,N.L., Goddard,M.E., Heard-Costa,N.L.,
            Hoesel,V., Hottenga,J.J., Johansson,A., Johnson,T., Ketkar,S.,
            Lamina,C., Li,S., Moffatt,M.F., Myers,R.H., Narisu,N., Perry,J.R.,
            Peters,M.J., Preuss,M., Ripatti,S., Rivadeneira,F., Sandholt,C.,
            Scott,L.J., Timpson,N.J., Tyrer,J.P., van Wingerden,S.,
            Watanabe,R.M., White,C.C., Wiklund,F., Barlassina,C., Chasman,D.I.,
            Cooper,M.N., Jansson,J.O., Lawrence,R.W., Pellikka,N.,
            Prokopenko,I., Shi,J., Thiering,E., Alavere,H., Alibrandi,M.T.,
            Almgren,P., Arnold,A.M., Aspelund,T., Atwood,L.D., Balkau,B.,
            Balmforth,A.J., Bennett,A.J., Ben-Shlomo,Y., Bergman,R.N.,
            Bergmann,S., Biebermann,H., Blakemore,A.I., Boes,T.,
            Bonnycastle,L.L., Bornstein,S.R., Brown,M.J., Buchanan,T.A.,
            Busonero,F., Campbell,H., Cappuccio,F.P., Cavalcanti-Proenca,C.,
            Chen,Y.D., Chen,C.M., Chines,P.S., Clarke,R., Coin,L., Connell,J.,
            Day,I.N., den Heijer,M., Duan,J., Ebrahim,S., Elliott,P.,
            Elosua,R., Eiriksdottir,G., Erdos,M.R., Eriksson,J.G.,
            Facheris,M.F., Felix,S.B., Fischer-Posovszky,P., Folsom,A.R.,
            Friedrich,N., Freimer,N.B., Fu,M., Gaget,S., Gejman,P.V.,
            Geus,E.J., Gieger,C., Gjesing,A.P., Goel,A., Goyette,P.,
            Grallert,H., Grassler,J., Greenawalt,D.M., Groves,C.J.,
            Gudnason,V., Guiducci,C., Hartikainen,A.L., Hassanali,N.,
            Hall,A.S., Havulinna,A.S., Hayward,C., Heath,A.C., Hengstenberg,C.,
            Hicks,A.A., Hinney,A., Hofman,A., Homuth,G., Hui,J., Igl,W.,
            Iribarren,C., Isomaa,B., Jacobs,K.B., Jarick,I., Jewell,E.,
            John,U., Jorgensen,T., Jousilahti,P., Jula,A., Kaakinen,M.,
            Kajantie,E., Kaplan,L.M., Kathiresan,S., Kettunen,J., Kinnunen,L.,
            Knowles,J.W., Kolcic,I., Konig,I.R., Koskinen,S., Kovacs,P.,
            Kuusisto,J., Kraft,P., Kvaloy,K., Laitinen,J., Lantieri,O.,
            Lanzani,C., Launer,L.J., Lecoeur,C., Lehtimaki,T., Lettre,G.,
            Liu,J., Lokki,M.L., Lorentzon,M., Luben,R.N., Ludwig,B.,
            Manunta,P., Marek,D., Marre,M., Martin,N.G., McArdle,W.L.,
            McCarthy,A., McKnight,B., Meitinger,T., Melander,O., Meyre,D.,
            Midthjell,K., Montgomery,G.W., Morken,M.A., Morris,A.P., Mulic,R.,
            Ngwa,J.S., Nelis,M., Neville,M.J., Nyholt,D.R., O'Donnell,C.J.,
            O'Rahilly,S., Ong,K.K., Oostra,B., Pare,G., Parker,A.N., Perola,M.,
            Pichler,I., Pietilainen,K.H., Platou,C.G., Polasek,O., Pouta,A.,
            Rafelt,S., Raitakari,O., Rayner,N.W., Ridderstrale,M., Rief,W.,
            Ruokonen,A., Robertson,N.R., Rzehak,P., Salomaa,V., Sanders,A.R.,
            Sandhu,M.S., Sanna,S., Saramies,J., Savolainen,M.J., Scherag,S.,
            Schipf,S., Schreiber,S., Schunkert,H., Silander,K., Sinisalo,J.,
            Siscovick,D.S., Smit,J.H., Soranzo,N., Sovio,U., Stephens,J.,
            Surakka,I., Swift,A.J., Tammesoo,M.L., Tardif,J.C.,
            Teder-Laving,M., Teslovich,T.M., Thompson,J.R., Thomson,B.,
            Tonjes,A., Tuomi,T., van Meurs,J.B., van Ommen,G.J., Vatin,V.,
            Viikari,J., Visvikis-Siest,S., Vitart,V., Vogel,C.I., Voight,B.F.,
            Waite,L.L., Wallaschofski,H., Walters,G.B., Widen,E., Wiegand,S.,
            Wild,S.H., Willemsen,G., Witte,D.R., Witteman,J.C., Xu,J.,
            Zhang,Q., Zgaga,L., Ziegler,A., Zitting,P., Beilby,J.P.,
            Farooqi,I.S., Hebebrand,J., Huikuri,H.V., James,A.L., Kahonen,M.,
            Levinson,D.F., Macciardi,F., Nieminen,M.S., Ohlsson,C.,
            Palmer,L.J., Ridker,P.M., Stumvoll,M., Beckmann,J.S., Boeing,H.,
            Boerwinkle,E., Boomsma,D.I., Caulfield,M.J., Chanock,S.J.,
            Collins,F.S., Cupples,L.A., Smith,G.D., Erdmann,J., Froguel,P.,
            Gronberg,H., Gyllensten,U., Hall,P., Hansen,T., Harris,T.B.,
            Hattersley,A.T., Hayes,R.B., Heinrich,J., Hu,F.B., Hveem,K.,
            Illig,T., Jarvelin,M.R., Kaprio,J., Karpe,F., Khaw,K.T.,
            Kiemeney,L.A., Krude,H., Laakso,M., Lawlor,D.A., Metspalu,A.,
            Munroe,P.B., Ouwehand,W.H., Pedersen,O., Penninx,B.W., Peters,A.,
            Pramstaller,P.P., Quertermous,T., Reinehr,T., Rissanen,A.,
            Rudan,I., Samani,N.J., Schwarz,P.E., Shuldiner,A.R., Spector,T.D.,
            Tuomilehto,J., Uda,M., Uitterlinden,A., Valle,T.T., Wabitsch,M.,
            Waeber,G., Wareham,N.J., Watkins,H., Wilson,J.F., Wright,A.F.,
            Zillikens,M.C., Chatterjee,N., McCarroll,S.A., Purcell,S.,
            Schadt,E.E., Visscher,P.M., Assimes,T.L., Borecki,I.B.,
            Deloukas,P., Fox,C.S., Groop,L.C., Haritunians,T., Hunter,D.J.,
            Kaplan,R.C., Mohlke,K.L., O'Connell,J.R., Peltonen,L.,
            Schlessinger,D., Strachan,D.P., van Duijn,C.M., Wichmann,H.E.,
            Frayling,T.M., Thorsteinsdottir,U., Abecasis,G.R., Barroso,I.,
            Boehnke,M., Stefansson,K., North,K.E., McCarthy,M.I.,
            Hirschhorn,J.N., Ingelsson,E. and Loos,R.J.
  CONSRTM   MAGIC; Procardis Consortium
  TITLE     Association analyses of 249,796 individuals reveal 18 new loci
            associated with body mass index
  JOURNAL   Nat Genet 42 (11), 937-948 (2010)
   PUBMED   20935630
REFERENCE   6  (bases 1 to 3294)
  AUTHORS   Prakash,T., Sharma,V.K., Adati,N., Ozawa,R., Kumar,N., Nishida,Y.,
            Fujikake,T., Takeda,T. and Taylor,T.D.
  TITLE     Expression of conjoined genes: another mechanism for gene
            regulation in eukaryotes
  JOURNAL   PLoS One 5 (10), e13284 (2010)
   PUBMED   20967262
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC098692.3, AC119672.1, AC093158.2, AC105271.2 and BX470253.2.
            
            On Jul 1, 2020 this sequence version replaced NM_001112808.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB208941.1, SRR18074969.1471217.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2151741, SAMEA2155550
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            readthrough transcript :: includes exons from GeneID 8790, 51086
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-119               AC098692.3         33854-33972
            120-287             AC098692.3         35276-35443
            288-380             AC098692.3         36930-37022
            381-489             AC098692.3         71714-71822
            490-575             AC119672.1         12823-12908
            576-673             AC119672.1         14036-14133
            674-784             AC093158.2         16843-16953
            785-883             AC093158.2         76695-76793
            884-1022            AC093158.2         81256-81394
            1023-1167           AC093158.2         88087-88231
            1168-1272           AC093158.2         88320-88424
            1273-1367           AC093158.2         98511-98605
            1368-1517           AC093158.2         99225-99374
            1518-1604           AC093158.2         112501-112587
            1605-1661           AC093158.2         113153-113209
            1662-1754           AC093158.2         114267-114359
            1755-1812           AC093158.2         114452-114509
            1813-2007           AC093158.2         114636-114830
            2008-2112           AC093158.2         115533-115637
            2113-2165           AC105271.2         42253-42305
            2166-2218           AC105271.2         42647-42699
            2219-2351           AC105271.2         45663-45795
            2352-2461           AC105271.2         69614-69723
            2462-2521           AC105271.2         95362-95421
            2522-2691           AC105271.2         98270-98439
            2692-2771           BX470253.2         36049-36128
            2772-3294           BX470253.2         39721-40243
FEATURES             Location/Qualifiers
     source          1..3294
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p31.1"
     gene            1..3294
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /note="FPGT-TNNI3K readthrough"
                     /db_xref="GeneID:100526835"
                     /db_xref="HGNC:HGNC:42952"
     exon            1..119
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..2848
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /EC_number="2.7.11.1"
                     /note="isoform a is encoded by transcript variant 1;
                     FPGT-TNNI3K fusion protein; Serine/threonine-protein
                     kinase TNNI3K; Cardiac ankyrin repeat kinase; Cardiac
                     troponin I-interacting kinase; TNNI3-interacting kinase"
                     /codon_start=1
                     /product="FPGT-TNNI3K fusion protein isoform a"
                     /protein_id="NP_001106279.3"
                     /db_xref="GeneID:100526835"
                     /db_xref="HGNC:HGNC:42952"
                     /translation="MAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITA
                     ADEKQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGD
                     KWNSFTILLIHSDEWKKKVSESYVITIERLEDDLQIKEKELTELRNIFGSDEAFSKVN
                     LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELI
                     TSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAA
                     YYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDN
                     EDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQ
                     ISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACY
                     HGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIVTLLKHYKRP
                     QDELPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEF
                     HEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQ
                     FVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLT
                     QPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQC
                     TRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSL
                     LIRGWNACPEGRPEFSEVVMKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGP
                     GRSHVAALRSRFELEYALNARSYAALSQSAGQYSSQGLSLEEMKRSLQYTPIDKYGYV
                     SDPMSSMHFHSCRNSSSFEDSS"
     exon            120..287
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            288..380
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            381..489
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            490..575
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            576..673
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            674..784
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            785..883
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            884..1022
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1167
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            1168..1272
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1367
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            1368..1517
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            1518..1604
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            1605..1661
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            1662..1754
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            1755..1812
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            1813..2007
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            2008..2112
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            2113..2165
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            2166..2218
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            2219..2351
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            2352..2461
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            2462..2521
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            2522..2691
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            2692..2771
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     exon            2772..3294
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3267..3272
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /note="hexamer: ATTAAA"
     polyA_site      3294
                     /gene="FPGT-TNNI3K"
                     /gene_synonym="CARK; TNNI3K"
                     /note="major polyA site"
ORIGIN      
        1 gcgtgctgtg cggcgcggtc tcagggaagg tggggctatg gcagctgcta gggaccctcc
       61 ggaagtatcg ctgcgagaag ccacccagcg aaaattgcgg aggttttccg agctaagagg
      121 caaacttgta gcacgtggag aattctggga catagttgca ataacagcgg ctgatgaaaa
      181 acaggaactt gcttacaacc aacagctgtc agaaaagctg aaaagaaagg agttacccct
      241 tggagttcaa tatcacgttt ttgtggatcc tgctggagcc aaaattggaa atggaggatc
      301 aacactttgt gcccttcaat gtttggaaaa gctatatgga gataaatgga attcttttac
      361 catcttatta attcactctg atgaatggaa gaaaaaagtc agtgaatcat atgttatcac
      421 aatagaaaga ttagaagatg acctgcagat caaggaaaaa gaactgacag aactaaggaa
      481 tatatttggc tctgatgaag ccttcagtaa agtcaattta aattaccgca ctgaaaatgg
      541 gctgtctcta cttcatttat gttgcatttg tggaggcaag aaatcacata ttcgaactct
      601 tatgttgaaa gggctccgcc catctcgact gacaagaaat ggatttacag ccttgcattt
      661 agcagtttac aaggataatg cagaattgat cacttctctg cttcacagtg gagctgatat
      721 acagcaggtt ggatacggtg gcctcactgc cctccatatt gctacaatag ctggccacct
      781 agaggctgct gatgtgctgt tgcaacatgg agctaatgtc aatattcaag atgcagtttt
      841 tttcactcca ttgcatattg cagcgtacta tggacatgaa caggtaactc gccttctttt
      901 gaaatttggt gctgatgtaa atgtaagtgg tgaagttgga gatagacccc tccacctagc
      961 atctgcaaaa ggattcttga atattgcaaa actcttgatg gaagaaggca gcaaagcaga
     1021 tgtgaatgct caagataatg aagaccatgt cccactccat ttctgttctc gatttggaca
     1081 ccatgatata gttaagtatc tgctgcaaag tgatttggaa gttcaacctc atgttgttaa
     1141 tatctatgga gataccccct tacacctggc atgctacaat ggcaaatttg aagttgccaa
     1201 ggaaatcatc caaatatcag gaacagaaag tctgactaag gaaaacatct tcagtgaaac
     1261 agcttttcat agtgcttgta cctatggcaa gagcattgac ctagtcaaat ttcttcttga
     1321 tcagaatgtc ataaacatca accaccaagg aagggatggg cacactggat tacactctgc
     1381 ttgctaccac ggtcacattc gcctggttca gttcttactg gataatggag ctgatatgaa
     1441 tctagtggct tgtgatccca gcaggtctag tggtgaaaaa gatgagcaga catgtttgat
     1501 gtgggcttat gaaaaagggc atgatgccat tgtcacactc ctgaagcatt ataagagacc
     1561 acaagatgaa ttgccctgta atgaatattc tcagcctgga ggagatggct cctatgtgtc
     1621 tgttccatca cccttgggga agattaaaag catgacaaaa gagaaggcag atattctcct
     1681 cctaagagct ggattgcctt cacatttcca tcttcagctc tcagaaattg agttccatga
     1741 gattattggc tcaggttctt ttgggaaagt atataaagga cgatgcagaa ataaaatagt
     1801 ggctataaaa cgttatcgag ccaataccta ctgctccaag tcagatgtgg atatgttttg
     1861 ccgagaggtg tccattctct gccagctcaa tcatccctgc gtaattcagt ttgtgggtgc
     1921 ttgcttgaat gatcccagcc agtttgccat tgtcactcaa tacatatcag ggggttctct
     1981 gttctccctc cttcatgagc agaagaggat tcttgatttg cagtctaaat taattattgc
     2041 agtagatgtt gccaaaggca tggagtacct tcacaacctg acacagccaa ttatacatcg
     2101 tgacttgaac agtcacaata ttcttctcta tgaggatggg catgctgtgg tggcagattt
     2161 tggagaatca agatttctac agtctctgga tgaagacaac atgacaaaac aacctgggaa
     2221 cctccgttgg atggctcctg aggtgttcac gcagtgcact cggtacacca tcaaagcaga
     2281 tgtcttcagc tatgctctgt gtctgtggga aattctcact ggcgaaattc cattcgctca
     2341 tctcaagcca gcggctgcgg cagcagacat ggcttaccac cacatcagac ctcccattgg
     2401 ctattccatt cccaagccca tatcatctct gctgatacga gggtggaacg catgtcctga
     2461 aggaagaccc gaattttctg aagttgtcat gaagttagaa gagtgtctct gcaacattga
     2521 gctgatgtct cctgcatcaa gtaacagcag tgggtctctc tcaccttctt cttcttctga
     2581 ttgcctggtg aaccggggag gacctggccg gagtcatgtg gcagcattaa gaagtcgttt
     2641 cgaattggaa tatgctctaa atgcaaggtc ctatgctgct ttgtcccaaa gtgctggaca
     2701 atattcctct caaggtctgt ctttggagga gatgaaaaga agtcttcaat acacacccat
     2761 tgacaaatat ggctatgtat ccgatcccat gagctcaatg cattttcatt cttgccgaaa
     2821 tagtagcagc tttgaggaca gcagctgaca gcattcggcg tatacctaag gagagttttt
     2881 tccccgaact gacagcaacg attccaacca cggcaagctg gcttccaact ataacatttt
     2941 actctcaaag gtctccttaa attgggcttg tttttacttg tcctatttaa ttccccacta
     3001 ttagcaggct ttggatttgt gcctaaggaa taatatgcaa aagaaccaag acagaatgta
     3061 tatgaagaat tgtttttaat tttgtaaatt aaaaaaaaat ttagatcgtt acttggaaat
     3121 ggagcctaag tctgtggtgg acagataata attatgtttt cctgggctga attatgtaga
     3181 cttgtgtttg acagctatgg gtttatttct tagaacattg ttcattttct tttctcatta
     3241 tgttacttct agtgttcacc tctgtgatta aagattcttt ggtgaaatag aaaa
//
