LOCUS       NM_001037165           11194 bp    mRNA    linear   PRI 03-SEP-2024
DEFINITION  Homo sapiens forkhead box K1 (FOXK1), mRNA.
ACCESSION   NM_001037165 XM_926946 XM_931704 XM_942582 XM_946134
VERSION     NM_001037165.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 11194)
  AUTHORS   Zhang,Z., Zhao,M., Wang,Q., Wang,X., Wang,Y., Ge,Y., Wu,Z., Wang,W.
            and Shan,L.
  TITLE     Forkhead box protein FOXK1 disrupts the circadian rhythm to promote
            breast tumorigenesis in response to insulin resistance
  JOURNAL   Cancer Lett 599, 217147 (2024)
   PUBMED   39094826
  REMARK    GeneRIF: Forkhead box protein FOXK1 disrupts the circadian rhythm
            to promote breast tumorigenesis in response to insulin resistance.
REFERENCE   2  (bases 1 to 11194)
  AUTHORS   Chen,H., Fu,X., Wu,X., Zhao,J., Qiu,F., Wang,Z., Wang,Z., Chen,X.,
            Xie,D., Huang,J., Fan,J., Yang,X., Song,Y., Li,J., He,D., Xiao,G.,
            Lu,A. and Liang,C.
  TITLE     Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in
            fibroblast-like synoviocytes to ameliorate rheumatoid arthritis
  JOURNAL   Bone Res 12 (1), 31 (2024)
   PUBMED   38782893
  REMARK    GeneRIF: Gut microbial metabolite targets HDAC3-FOXK1-interferon
            axis in fibroblast-like synoviocytes to ameliorate rheumatoid
            arthritis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 11194)
  AUTHORS   Chen,S., Pan,X., Zhang,L., Cui,X. and Ye,J.
  TITLE     FOXK1 upregulation is correlated with tumor progression and tumor
            associated macrophages infiltration in renal cell carcinoma
  JOURNAL   Mol Carcinog 63 (1), 136-144 (2024)
   PUBMED   37818826
  REMARK    GeneRIF: FOXK1 upregulation is correlated with tumor progression
            and tumor associated macrophages infiltration in renal cell
            carcinoma.
REFERENCE   4  (bases 1 to 11194)
  AUTHORS   Duan,L., Huang,J., Zhang,Y., Pi,G., Ying,X., Zeng,F., Hu,D. and
            Ma,J.
  TITLE     FOXK1 regulates epithelial-mesenchymal transition and radiation
            sensitivity in nasopharyngeal carcinoma via the JAK/STAT3 signaling
            pathway
  JOURNAL   Genes Genomics 45 (6), 749-761 (2023)
   PUBMED   37043129
  REMARK    GeneRIF: FOXK1 regulates epithelial-mesenchymal transition and
            radiation sensitivity in nasopharyngeal carcinoma via the JAK/STAT3
            signaling pathway.
REFERENCE   5  (bases 1 to 11194)
  AUTHORS   Li,X., Lu,J., Liu,L., Li,F., Xu,T., Chen,L., Yan,Z., Li,Y. and
            Guo,W.
  TITLE     FOXK1 regulates malignant progression and radiosensitivity through
            direct transcriptional activation of CDC25A and CDK4 in esophageal
            squamous cell carcinoma
  JOURNAL   Sci Rep 13 (1), 7737 (2023)
   PUBMED   37173384
  REMARK    GeneRIF: FOXK1 regulates malignant progression and radiosensitivity
            through direct transcriptional activation of CDC25A and CDK4 in
            esophageal squamous cell carcinoma.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 11194)
  AUTHORS   Vaquerizas,J.M., Kummerfeld,S.K., Teichmann,S.A. and Luscombe,N.M.
  TITLE     A census of human transcription factors: function, expression and
            evolution
  JOURNAL   Nat Rev Genet 10 (4), 252-263 (2009)
   PUBMED   19274049
  REMARK    Review article
REFERENCE   7  (bases 1 to 11194)
  AUTHORS   Freddie,C.T., Ji,Z., Marais,A. and Sharrocks,A.D.
  TITLE     Functional interactions between the Forkhead transcription factor
            FOXK1 and the MADS-box protein SRF
  JOURNAL   Nucleic Acids Res 35 (15), 5203-5212 (2007)
   PUBMED   17670796
REFERENCE   8  (bases 1 to 11194)
  AUTHORS   Tsai,K.L., Huang,C.Y., Chang,C.H., Sun,Y.J., Chuang,W.J. and
            Hsiao,C.D.
  TITLE     Crystal structure of the human FOXK1a-DNA complex and its
            implications on the diverse binding specificity of winged
            helix/forkhead proteins
  JOURNAL   J Biol Chem 281 (25), 17400-17409 (2006)
   PUBMED   16624804
  REMARK    GeneRIF: crystallographic analysis of the FOXK1a-DNA complex
REFERENCE   9  (bases 1 to 11194)
  AUTHORS   Huang,J.T. and Lee,V.
  TITLE     Identification and characterization of a novel human FOXK1 gene in
            silico
  JOURNAL   Int J Oncol 25 (3), 751-757 (2004)
   PUBMED   15289879
REFERENCE   10 (bases 1 to 11194)
  AUTHORS   Katoh,M. and Katoh,M.
  TITLE     Identification and characterization of human FOXK1 gene in silico
  JOURNAL   Int J Mol Med 14 (1), 127-132 (2004)
   PUBMED   15202027
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC072054.10, AC092428.4 and AC092610.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001037165.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1965299,
                              SAMEA1966682 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000328914.5/ ENSP00000328720.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-574               AC072054.10        129312-129885
            575-760             AC092428.4         35818-36003
            761-917             AC092610.1         9616-9772
            918-1064            AC092610.1         10394-10540
            1065-1258           AC092610.1         12151-12344
            1259-1425           AC092610.1         14208-14374
            1426-1710           AC092610.1         14468-14752
            1711-1935           AC092610.1         16221-16445
            1936-11194          AC092610.1         17341-26599
FEATURES             Location/Qualifiers
     source          1..11194
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7p22.1"
     gene            1..11194
                     /gene="FOXK1"
                     /gene_synonym="FOXK1L"
                     /note="forkhead box K1"
                     /db_xref="GeneID:221937"
                     /db_xref="HGNC:HGNC:23480"
                     /db_xref="MIM:616302"
     exon            1..574
                     /gene="FOXK1"
                     /gene_synonym="FOXK1L"
                     /inference="alignment:Splign:2.1.0"
     CDS             15..2216
                     /gene="FOXK1"
                     /gene_synonym="FOXK1L"
                     /note="myocyte nuclear factor; MNF"
                     /codon_start=1
                     /product="forkhead box protein K1"
                     /protein_id="NP_001032242.1"
                     /db_xref="CCDS:CCDS34591.1"
                     /db_xref="GeneID:221937"
                     /db_xref="HGNC:HGNC:23480"
                     /db_xref="MIM:616302"
                     /translation="MAEVGEDSGARALLALRSAPCSPVLCAAAAAAAFPAAAPPPAPA
                     QPQPPPGPPPPPPPPLPPGAIAGAGSSGGSSGVSGDSAVAGAAPALVAAAAASVRQSP
                     GPALARLEGREFEFLMRQPSVTIGRNSSQGSVDLSMGLSSFISRRHLQLSFQEPHFYL
                     RCLGKNGVFVDGAFQRRGAPALQLPKQCTFRFPSTAIKIQFTSLYHKEEAPASPLRPL
                     YPQISPLKIHIPEPDLRSMVSPVPSPTGTISVPNSCPASPRGAGSSSYRFVQNVTSDL
                     QLAAEFAAKAASEQQADTSGGDSPKDESKPPFSYAQLIVQAISSAQDRQLTLSGIYAH
                     ITKHYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASEAKLVEQ
                     AFRKRRQRGVSCFRTPFGPLSSRSAPASPTHPGLMSPRSGGLQTPECLSREGSPIPHD
                     PEFGSKLASVPEYRYSQSAPGSPVSAQPVIMAVPPRPSSLVAKPVAYMPASIVTSQQP
                     AGHAIHVVQQAPTVTMVRVVTTSANSANGYILTSQGAAGGSHDAAGAAVLDLGSEARG
                     LEEKPTIAFATIPAAGGVIQTVASQMAPGVPGHTVTILQPATPVTLGQHHLPVRAVTQ
                     NGKHAVPTNSLAGNAYALTSPLQLLATQASSSAPVVVTRVCEVGPKEPAAAVAATATT
                     TPATATTASASASSTGEPEVKRSRVEEPSGAVTTPAGVIAAAGPQGPGTGE"
     exon            575..760
                     /gene="FOXK1"
                     /gene_synonym="FOXK1L"
                     /inference="alignment:Splign:2.1.0"
     exon            761..917
                     /gene="FOXK1"
                     /gene_synonym="FOXK1L"
                     /inference="alignment:Splign:2.1.0"
     exon            918..1064
                     /gene="FOXK1"
                     /gene_synonym="FOXK1L"
                     /inference="alignment:Splign:2.1.0"
     exon            1065..1258
                     /gene="FOXK1"
                     /gene_synonym="FOXK1L"
                     /inference="alignment:Splign:2.1.0"
     exon            1259..1425
                     /gene="FOXK1"
                     /gene_synonym="FOXK1L"
                     /inference="alignment:Splign:2.1.0"
     exon            1426..1710
                     /gene="FOXK1"
                     /gene_synonym="FOXK1L"
                     /inference="alignment:Splign:2.1.0"
     exon            1711..1935
                     /gene="FOXK1"
                     /gene_synonym="FOXK1L"
                     /inference="alignment:Splign:2.1.0"
     exon            1936..11194
                     /gene="FOXK1"
                     /gene_synonym="FOXK1L"
                     /inference="alignment:Splign:2.1.0"
     regulatory      11169..11174
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FOXK1"
                     /gene_synonym="FOXK1L"
                     /note="hexamer: AATAAA"
     polyA_site      11194
                     /gene="FOXK1"
                     /gene_synonym="FOXK1L"
                     /note="major polyA site"
ORIGIN      
        1 ggagccgcgc gaacatggcc gaagtcggcg aggacagcgg cgcccgcgcc ctgctcgcgc
       61 tgcgctcggc gccctgcagc ccagtgctgt gcgccgcagc cgccgccgcc gccttccccg
      121 cggccgcacc cccgccggcc cccgcgcagc cccagcctcc gcccgggccg ccgccgccgc
      181 cgccaccgcc gctgcctccg ggcgcgatcg cgggcgcggg ctcctccggg ggctcctccg
      241 gggtatccgg ggactccgcg gtcgcgggcg cggcgccggc cctggtggcc gcggcggccg
      301 cctcggtacg gcagagcccg gggccggcgc tggcgcggct ggagggccgc gagttcgagt
      361 tcctcatgcg ccagcccagc gtcaccatcg gccgcaactc gtcgcagggc tcggtggact
      421 tgagcatggg cctgtccagc ttcatctcgc ggcgccacct gcagctcagc ttccaggagc
      481 cgcacttcta cctgcgctgc ctcggcaaga acggcgtctt cgtggacggg gccttccaga
      541 gacgcggcgc gcccgccctg cagctgccca agcagtgtac cttccggttt cccagcacgg
      601 ccatcaagat ccagttcacg tcgctctatc acaaagaaga ggccccagcc tccccgctgc
      661 ggccactgta cccccagatc tcccctctga agatccacat cccggagccg gacctccgga
      721 gcatggtcag ccccgtcccc tccccgacgg gcaccatcag tgtccccaac tcctgcccag
      781 ccagtccacg cggtgccggc tcctccagtt accgctttgt gcagaacgtg acctcggacc
      841 tgcagctggc agcagagttt gcagcaaagg ccgcgtcgga gcagcaggca gacacgtctg
      901 gaggagacag ccccaaggat gagtcaaagc cgccgttctc ctacgcgcag ctgatcgtgc
      961 aggccatctc ctccgcccag gaccggcagc tgaccctgag cgggatctac gcccacatca
     1021 ccaagcatta cccctactac cggacggccg acaaaggctg gcagaattct atccggcaca
     1081 acctctcttt gaaccgttac tttatcaaag tcccacgttc ccaggaggag cctgggaagg
     1141 ggtccttttg gcgaatagac cctgcctctg aagccaagct cgtggaacag gcattccgga
     1201 aacggaggca gaggggtgtc tcctgcttcc gcaccccctt cgggcctctg tcctcaagga
     1261 gcgctccagc ttcgcccaca caccccgggc tgatgtcccc tcgctccggc ggcctgcaga
     1321 ccccagagtg cctgtctcgg gagggctccc ccattccaca cgaccctgag tttgggtcca
     1381 agttagcttc tgtcccagag taccggtatt cccaaagcgc acccggctcc cccgtcagcg
     1441 cccagccagt gatcatggcc gtgcctcccc gaccgtccag cctcgtggcc aagcccgtgg
     1501 cctacatgcc cgcctccatc gtaacctcac agcagcccgc gggccacgcc atccacgtcg
     1561 tgcagcaggc ccccaccgtc accatggtca gggtggtcac cacatctgcc aactcggcca
     1621 acggatacat cctcaccagc cagggcgcgg cggggggctc ccatgatgcg gcgggcgcag
     1681 ccgtgctgga cctgggcagc gaggccagag gcctggagga gaaacccacc attgcgtttg
     1741 ccacaatccc cgcggctggt ggagtcatcc agacggtggc cagccagatg gcccccgggg
     1801 tccccggaca cacggtcacc atcctgcagc ccgccacacc cgtgaccctc gggcagcacc
     1861 accttccagt ccgggccgtg acccagaacg gaaagcatgc ggttcccacg aacagtttag
     1921 ccggcaacgc ttacgccctc accagccctt tgcagctcct tgcgacccaa gcgagttcat
     1981 ccgcgccggt ggtggtcacc cgggtgtgcg aggtggggcc caaggagcca gcagcagccg
     2041 tcgcggccac ggccaccacc accccagcca ctgccaccac cgcctctgcc tccgcctctt
     2101 ccactggaga gcccgaggtc aaaaggtccc gggtggagga gcccagtggt gctgtaacca
     2161 caccggctgg agtgatcgca gctgccggcc cccaggggcc aggcaccggg gagtgaggtc
     2221 acctgcaacg cgggggagtg ggactcaccc agcggcgacc ccgaagctgg acccggcagc
     2281 tcaggcggcc gcacccacag acggaggaga acagcccgcg gcggcctgtg ggcatcggcg
     2341 gcacctggac acacccagcc ctttccattt gatcgcctgc cttcccgtgg tttaagacaa
     2401 aaacacataa acaagttcag acaactgatt gtatgattct gggaattctt tgctttcctt
     2461 tccttctccc tcggcaccac ctcctctccc caggcctccc tgtcgggcat ggggaggagg
     2521 ttggagctca gcatcttgag gaatgtgtca agacagcccc tccgctccgc gctgcacggc
     2581 cagccgcctt tgtccgggag gacagacaga aacgcagcaa ggcacacacc aaggctgccg
     2641 gggaggcccg ggcaccggac agatgcctgt tgggaagcca ggagctgccg agccacggac
     2701 cacctaacag cctctccgcc cggaacgtga catagagagt gttggcatta actcgggggg
     2761 tgtccgattt cacttcagac cccaagtttt tctttgtttg tttaaacatg gaattcagac
     2821 ttcattgtac acctgagaca gacacaaaag ggatcatgta tttttgagga ttttacctgt
     2881 tgacgtctga tgaccggccg taggtccagg gttcccgctg ggtttaatcc cctcgaagag
     2941 taaacctgcc gctctgtctg ataacttcaa gtaagagcag cggcttcctg ggttggcgtt
     3001 cgcggtggaa ggttcctagg atgaaaggtg agcctggatc cgccggccgc agacatcgcg
     3061 ctgctgggga cgattggggc cgctgctctg cagaccagac cttcccgaat tatccgtggc
     3121 tccgatgtcc cggtgctgac ggccacatgg ggacctaaca gtgccaaacg ccatctgctc
     3181 cagctgcttt ttcacccagt tgcagagtcc tcaccactcc cacattgatc tgctgttttc
     3241 aattggaacc atttctcctg cctgaaactc cagggcccct ccctgggctg tccgtgagca
     3301 ggagacccca ccccagcagc agtggtgagc aggcctgtgc ctccacgccc agcccccgcc
     3361 aacgcgactg gttttgtttg ccacacggtg agaaccggag gacgggatgc tccagccagt
     3421 tgggtggttc tggggtccct gaggaagccc cctcctgcac ttccattaag acagccagtg
     3481 gttcctggat ctttgtcacc aagcagcgtt gagccagagc tgtctaatgc tgagcccagc
     3541 tcaggaagga gagaggagtc cttcagtgtg tcttggagat gcgaagtgcg tcctcgtaaa
     3601 ggtcagctgt cagttttgct ggccgctccg gcgctggctc tcctgtccgg gaccacaacg
     3661 agaaacagcg acagattcga cgcagagctc cggaagtgcc tgaggagcag tggttcttgg
     3721 aaatcgcccg tcctccgcat cacagcctct caccagcaaa gcagcctctg cccaggccct
     3781 ggcgggagag ctgcagaggg acccaggtgc ctggagggca tttgagggag gtggctggac
     3841 aggtgtctcc ctgaagaaga agggagaaca cttttcaaag tgattccgag gcagtgcggg
     3901 aggacacacg tgctgtgcag tggagtgggg tcgcccgtgg cccccatcag agtccccgtc
     3961 ccccaggaca agtgcagaac ctctgtgggc cccctccttc cacctagata gagaaaaccc
     4021 cttgttcggt ttccttcccg tgtcccgttg tttttctaag ccccccgaat tgagtcgttt
     4081 ctatggcact aacctttcca tgggaaataa gctctttgtg gaagtccgta cctgttgccc
     4141 tgggtgaggt ttcagagaaa cgggggcagg atgaacacag ccggctgtcc tgggtgcagt
     4201 tacgtccgtg gagggtgaga gattgcgccc cgttccacac ttgtgtcgcc tgctgttgtc
     4261 tgtgggcctt ttctttccgt ggtgcctggt gtgtgcgtgc atggcgtgag agaacggggg
     4321 gtgggggttg gaggtggctc cccgacaccg gtgcctgtgt ggcctgagcc ggcgccctcc
     4381 cgggagcgcc cgtcacgggg ggcctctgtg attacctgct gctgctctct cccgcgtggt
     4441 gactatatgt cctcagggct gcctgtggcc accctgatgg gagacctctg tttgcttctg
     4501 ggccactgca ggttggcctc ctcaatacaa gctgatgtct gcagggagcg ccgcgtgctg
     4561 ggattgcacc acgtgttggt cacaaatcga ggtcgccttt tggcctggtc tgctcaggct
     4621 ggccctgacc cacgtggttt cctggcttct gagacgcagc gcattcttcc tgttagcggt
     4681 agcgttctct gatttcactg cttcattgcc aagggcgtgg aaagggggtg gtggatggag
     4741 ccgggaggtg gcgagcacag gaccccgggg ctgcattctg ccgtgtgggg ttctgcactg
     4801 tctagcttct gcggggactg caaagaggga tgaagggacg tggtcctagg ggtcggctca
     4861 gactcggagc agggcaggga gaggagggca aggagaggag gcctgggtcc tggatccact
     4921 gctctgggct cataaccatg agattttgaa agagtttttg gtcatctgag caggtaccat
     4981 gcctggctca tgccggaact tgtcttggaa ccggtagcca gaggcccagg aagggacagg
     5041 gcccaaaagg gttgcatgtc ccggccacaa agccctccct gtgtgccctg agccagccca
     5101 gcaagcgcct cccagccagg cgctttcgca gaagcaagag cacaggccag ggggaccggg
     5161 agagcctcag cccccagcct gggcggcctg tgaccctgag ccgtgtggag ccaggaccca
     5221 agaaccttct ctaggttctc aagggtgagc tgacccgggc aatgtgcagg aatgtgggga
     5281 gcaaaagtag ctgattccag ccccgttctg gggtcactgg ggaggcagag gctgagggcc
     5341 tgttctctgg tcaccaggga ctgggggcac ggtccacagc ggatgagaac agcaggtcac
     5401 agtagtggct ttgggaaggg cccctcctgc tttgccctgt tcggaaaggg gctccctcag
     5461 agcccctggg cccagtaacc cgcttctgtc tcctgactcc tgctggataa attgccaggt
     5521 ttatcaaata caagaaaaca cctgctttgg ctaggaggta agtcccaaaa agaacgtctt
     5581 aagtagagca aaggcatcca ccgaggccat ttggtggccc ctgggaagtg gggaagcagg
     5641 gcctgagcgt ccccaggctg ctagggcagc agctggctca gggcacactc tctcgtgcca
     5701 gcttctgcca ccagcccagt gtccacggag ccgcggggcc agaggagctc agggagacct
     5761 ggctgtctag ggcatggtac ccagtatccc ggtgtgtgcc catcctcagc cacttgtgtc
     5821 tttctttcca tgtgggagtt ctcccggtga cacctgccct ccgttgaggg tggaatctgt
     5881 cactcatgcc tttgagggac ccagatggac catccctctt ctgcttgctt tctacattcc
     5941 taaaaacctc aacgttaatc cctcaccagt cgggccgagt gtggcctcat ggttctgccg
     6001 cggcccagtc ttctcccact ggcttcacgc tagagggcgc catgcgctct gggtgaaatg
     6061 agacgctggt gtggggtccc catgtagaga ccctcaggtc cctatccaga gaccctccag
     6121 gcagtgctgg gaagacactg gtggcgggga ccatgaccag gcgggtggag ccatgtgtgt
     6181 ctcacacctg ccgcccctca ctttccttcc cgaggtctgg taggtcctct ttgggatttg
     6241 ctgtttattt gtatctccct tttctttgat ttaagaacaa tgccaagtga aaaagctggg
     6301 aatgaatttc tgagttgctg agtgttccct gctcctaggt accacgctct gtgcttctca
     6361 ggcagggagg agatggattc ggtggagttg ggccaggacg ggggcttcac cctgccccct
     6421 ccagactgcc gaagccccca agaagttttg agcccagctg ggcctcgcct ccccggctcc
     6481 tgggtccatt ttctgtactg gtttgagatc acaggcatca ttcagcgaat gctcttgtgt
     6541 cctctgcata aagagggccc tccctggagc acccccgggg agctgggact ctccagaaag
     6601 ccccgggtga gggctccgtc ttgagagaga gagaaatccc ttctttgggc gattcagtga
     6661 gttcaggagg aggaggaagc ttttccttgg ctttgaaatc agtgttttta tggagacaaa
     6721 gaacagacct cagtgggaaa aatgaaaacg taatggaaca cggggaggtg tcggagaaga
     6781 aaggattttc cccttcgctt tcagagccgg cgggagtgca ggtctgtttt gcttcagaag
     6841 cctcacattc tgctttgccc ttgagtgact tcatgcggga tgaggaactg ttgacccctc
     6901 tagagaggac accccaagtc catcctgggc tcctcctcac ccctctgaga aagcccccct
     6961 aaaaaaaggc ttcagagtca ccggcatgcc gcctcacgtt gcaggacgga atcgcgcgct
     7021 cctcacgctg gagtaagtta cgaaacatga tcgtcaggct ctttgcaaac gcagagcccc
     7081 agaacgctgg atggaggcct cctcggccct gcgggcggcc tggctgcggt aggtctgctg
     7141 caaggagcca ccacggggac tgcgccacac tcctgatgaa aacgtgttta cccacagcct
     7201 cgcctcgagc ctccttgaca ataccgctgc ttcaaagcaa tattatttaa tgagaatact
     7261 ttacattgct cacatgtgct gctatgaaga caggattagt ctgtagacgg gactcagctc
     7321 cagaggttcc tgggtaatgt attgtggctc ttggaaatga gggtagaatt tgaaatataa
     7381 caaatggtct ctcgcccggt tctgtccctt atttttagat tgttttcctg catcttacaa
     7441 tttccttttc ttttcaaagt tcctttctcc aggcctgttt ttcagtgctc aggacacggt
     7501 tttcatcaca tacttactgt ttttttggtt gggttttgat acgaaaagct gctacgtttg
     7561 gtgaccagag ggagggtttg gaatctgtgc tttgcagggg atctcggtgg gtaccgcggc
     7621 ccctcgcagg gtggcgagtg gggtccgtgc ctcgagaagg gggcccttac ccacaccgtg
     7681 cggcttgaat tctgtcggag ttgaatctgt ggaaaggatt gtcccattag agctgctgcg
     7741 tcctttcctc tgtcctccct gtcacccaaa ccccgaagtc acagctgctt agaagaatgg
     7801 gattttgggg atacaaccac acacatttcc ctctggactg aaattttaaa aacagaccca
     7861 tttcactgac ttcttttttt tttttttttt tttttttttt ttgagacgga gtctcgctct
     7921 gtcgcccagg ctggagtgca gtggcgtgat ctcggctcac tgcaagctcc gcctcccggg
     7981 ttcacgccat tctcctgcct cagcctcccg agtagctggg actacaggcg cccgctacca
     8041 cgcccggcta attttttgta tttttagtag agacggggtt tcaccgtgtt agccaggatg
     8101 gtctcgatct cctgacctcg tgatccgccc gcctcggcct cccaaagtgc tgggattaca
     8161 ggcgtgagcc accgcgcccg gcccactgac ttctttaggg aaaatagttt cagtcttggg
     8221 ttgtcttgtg agcccacggg catgggaccc tgtctctgct gggcttttcc ggccccgtcc
     8281 cagctcctcc tcaggcagag gctgcagccc tcagctctgc tgctggatgg aacatttcaa
     8341 ccccctccgg gaaggtgggc agggtggagg gcccagggct aggcctgcca tgcaccatga
     8401 gcaggggtgc tacctgggtg tgtgaagttg ggctggcttt tcctggaggt gggtgagaag
     8461 gctctccggg caaatcagaa ggccacgaga gagagaggag cggggagagt ggtgaggagg
     8521 attcgtctct gactgatgaa cctcgccgtg cctgtctgtc acatccaagt ctgtgccagc
     8581 tgctgggagg tcagactcct gccctgagaa acagcccagt ccttggagaa tgaaaccctg
     8641 agggtcagtg agtggaggcc ttccctcggg gccagccatt cccgggaggc ctgagtgtga
     8701 cctggaagct ctgtgggtca ccaagactgg cattttcctt gtatttttgt gcagggctga
     8761 agtgagcgtt cctcctctga attggtgagg ctttggaaat tttttgtttc ttctactcat
     8821 cctaatggct ggttttggct gcccggagta tcagagaata tcactaagag ggcagtcagt
     8881 ttatttttag gcatctttct ttctgtccag ggagaaaccc ctcggaagaa tcttagtcac
     8941 tctttgcacc tgccctgtca ttctcgccat ggggaaaatg cgttgaaaag aaaaataccg
     9001 gggccaggga gaagccgtga atgtatttat ttgctttggt gaagctgctg aacactggct
     9061 gcggagggcc ccccgccccc atcccgcttc aggccccagt gacccagttg cgtcttaagt
     9121 tccatcgtcc agatttcagg ccaccagagg ctgccaaagg tgactgaagc ggtctccaag
     9181 tcactctgtc accacttttt ttttttttga gatggagtct cgctctatcg cccaggctgg
     9241 agtgcagtgg cccaatctcg gctcactgca acctccgcct cccaggttcg agcgaattct
     9301 cctgcctcaa cctcccaagt agctgggatt acaggcacct gccaccacac ccggctaatt
     9361 tttgtatttc taatagagat gagagtgtta ccatgttggt caggctggtc ttgaactcct
     9421 gacctcaggt gatctgccca cctcaacctc ccaaagtgct gggattatag gcatgagcca
     9481 ccgcgcctgg cctctgtcac tttttttgct ccttacccag tttttgtttt ttgttgtttt
     9541 gttttgtttt agcgtgatac tacaatggaa agactcctag ttggttattc tttatctcgg
     9601 attctttttt ctggaattgt ttgctcattt gagtggttgg tggtttgccc tgtgtcagac
     9661 acggtgaaaa gagtgcagga aagctggggc caggggaagc gaagtggctt caatccgggc
     9721 tgacagccaa gaagagtttt cctcccttcg gtgacagggc ctgcccctcc gagtctagag
     9781 gtaaaagcag cttctagaac tggcccctaa gtctccaaat gtgttggcta agctgaaatg
     9841 agagactctg aattagagtt tttgtttgtt tgtttgttct ctgcatgaag ttcacaggcc
     9901 tgtatggatg ttaaattgtg tctatagcct ctaaatctcc aggttaactg gtccagattt
     9961 ttttttttta atcagtaaca atgggaattt aaaatcaaat atttggccag gtgcggtggc
    10021 tcatgcccgt aatcccagca ctttgggagg ccgaggcagg cgcatcacct gaggagtttg
    10081 agaccagcct gaccaacatg gtgaaatcct gtctctacta aaaatacaaa aaattagcca
    10141 ggcgtggtgg cgtgtgcctg taatcccagc taccagggag gctgaggcat gagaatcgct
    10201 tgaacctggg agatggaggt tgcagtgagc cgagatcatg ccactgcact ccagcctggg
    10261 caacagaggg agactctgtc tcaaaaataa taatcaaatc aagtatttta agtttggctc
    10321 ttcttttttt caagaaaggc tttttggata cctagaatac cttcatgtat gtggcttgat
    10381 ttctgtttca ggaaaagggg ggcgggagga gagacaacag ccgtgttcca gagtctgtcc
    10441 tgagatgtcg ctgagtccag acacttgggc tgcacgtgcc ctgcagatga caaaggccgg
    10501 cagctcagca cacgtgcagg aggggttaaa gccaatattg agtttttgtt cttgttgttt
    10561 taatctgaac gattattctc ctgtaaaaat aatttgggag gggcgggtgt tgttcggtgt
    10621 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtattttt ttttttacag tggcgcctgt
    10681 ctaaagtatt tttcacaaca tgtttgataa tcagtgcttt aaaaagcagc agtgtcctat
    10741 gaagtggaaa tgtcagttct agagcattgg atgtgaagtt ctggtcatgt caccttgcgt
    10801 gtctcaccct ggaggagtga aggtgggcgc ccggcggggg ggtgtggctg caccccagca
    10861 ccgggagggg gcacgcacga caccagagga agggacagcc ccacccatgt caacagcagg
    10921 caacctgtgt tttcatttca agtgggatac agtatttttt taataaggag ccatactttt
    10981 ttttaagagt ttgagatctg aatgtgattt ctaattgtat cagacgttaa tgttttaaag
    11041 ctataacaaa gtttaaaatt tctacttttt gtttttcatt tattttaact gttcttttat
    11101 ctattaaatt gttgtatgtg gatggggaag ttttgtttct cctcttagca tttgtttcta
    11161 taaccagaaa taaaattcta tattaaagaa atga
//
