LOCUS       NM_001144937            3090 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens fibronectin type III domain containing 7 (FNDC7),
            mRNA.
ACCESSION   NM_001144937
VERSION     NM_001144937.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3090)
  AUTHORS   Jiang,H., Chu,B.L., He,J., Liu,Z. and Yang,L.
  TITLE     Expression and prognosis analyses of the fibronectin type-III
            domain-containing (FNDC) protein family in human cancers: A Review
  JOURNAL   Medicine (Baltimore) 101 (49), e31854 (2022)
   PUBMED   36626432
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591719.8, BC130421.1 and BC057762.1.
            
            On May 17, 2019 this sequence version replaced NM_001144937.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by orthologous data.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1966682, SAMEA1968968
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000370017.9/
                                                ENSP00000359034.3
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-89                AL591719.8         16199-16287
            90-108              AL591719.8         16802-16820
            109-363             AL591719.8         21068-21322
            364-624             AL591719.8         22080-22340
            625-700             AL591719.8         25626-25701
            701-1358            BC130421.1         1-658
            1359-3083           BC057762.1         706-2430
            3084-3090           AL591719.8         46034-46040
FEATURES             Location/Qualifiers
     source          1..3090
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p13.3"
     gene            1..3090
                     /gene="FNDC7"
                     /note="fibronectin type III domain containing 7"
                     /db_xref="GeneID:163479"
                     /db_xref="HGNC:HGNC:26668"
     exon            1..89
                     /gene="FNDC7"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..2228
                     /gene="FNDC7"
                     /note="fibronectin type III domain-containing protein 7"
                     /codon_start=1
                     /product="fibronectin type III domain-containing protein 7
                     precursor"
                     /protein_id="NP_001138409.1"
                     /db_xref="CCDS:CCDS44185.1"
                     /db_xref="GeneID:163479"
                     /db_xref="HGNC:HGNC:26668"
                     /translation="MAGGRETCLPLIGFILICLKMVASAKSAPEIPTIDQAYSKLSNS
                     ITVEWATVPGATSYLLTAEDGDTVIETTVANSPGTVTGLKAATWYEITIRSISAAGRS
                     QASPPKQAKTVLAAPILEVSSPSSDSILVQWEAVYMAIAFSVSIMRANGLGSIWKENT
                     TNTSLTFTSLEAGTLYTIKAYAWNANRIPGDDSTCNQRTSPRAPANIQVSFDSGALKA
                     SFSWARAEGAFNYTVMALSDSSELTCSTTFSSCTISSLQCGTEYLISVLASNDAGSSK
                     SSSAMTLKTVACAPGRVTIQEDPPGHLSVAWSSVDLGDYYVVFVKSDDGLEVHCNTSL
                     TQCNFLSECGFTYFISVFVYNKAGQSPLGDIFNYTTAPCCPSDINPVLVSSDRVEIVW
                     SPVRGAELYETKAVDGYNMVECNDTTPACTLSALECDTKYNITVYSFNEVRGSNMSCT
                     PQFITTAPCSPEIKNVSRDAFSMINVHWRSTNDDATYTVTAQGEKGLYQCSSTGESCT
                     MRGLPCGSVFSVTAVAETQAGRSLPSYSVPLETVPCCPTGLTVTQITQSVINVSWTIG
                     RVAQTHVAVLESHTGQSKCHTHQNHCLLGCITCGINYTVTLKAISATGLTADCSYQSY
                     FSGACCPLGVKLYRLGPNGIRIYWQASRGSANYSTDLYGSKGIFTCTPSAGLSFCDVT
                     EIPCGDVYTVMVSPVAKTGLKLTFCPKKIYSVTCSGSTLGMVIYRGKRNEE"
     exon            90..108
                     /gene="FNDC7"
                     /inference="alignment:Splign:2.1.0"
     exon            109..363
                     /gene="FNDC7"
                     /inference="alignment:Splign:2.1.0"
     exon            364..624
                     /gene="FNDC7"
                     /inference="alignment:Splign:2.1.0"
     exon            625..882
                     /gene="FNDC7"
                     /inference="alignment:Splign:2.1.0"
     exon            883..1137
                     /gene="FNDC7"
                     /inference="alignment:Splign:2.1.0"
     exon            1138..1395
                     /gene="FNDC7"
                     /inference="alignment:Splign:2.1.0"
     exon            1396..1650
                     /gene="FNDC7"
                     /inference="alignment:Splign:2.1.0"
     exon            1651..1905
                     /gene="FNDC7"
                     /inference="alignment:Splign:2.1.0"
     exon            1906..2166
                     /gene="FNDC7"
                     /inference="alignment:Splign:2.1.0"
     exon            2167..2196
                     /gene="FNDC7"
                     /inference="alignment:Splign:2.1.0"
     exon            2197..2265
                     /gene="FNDC7"
                     /inference="alignment:Splign:2.1.0"
     exon            2266..3090
                     /gene="FNDC7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3060..3065
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FNDC7"
                     /note="hexamer: AATATA"
     polyA_site      3083
                     /gene="FNDC7"
                     /note="major polyA site"
ORIGIN      
        1 gccatgtgag tactatgtcc aacaggatgg ctggtggacg agagacatgt ttgcctttga
       61 ttggattcat tcttatctgt cttaaaatgg ttgcttcagc aaaatcagct cctgaaatac
      121 ccactattga tcaggcatat tcaaaactca gcaacagtat cactgtagaa tgggctacag
      181 tgccgggtgc caccagttac ctcctcacgg ctgaagacgg ggacacagtc attgaaacca
      241 cggtggccaa ttccccaggc actgtgacgg gactaaaggc tgcaacctgg tatgaaatca
      301 ccatcagatc catcagcgct gctgggagaa gccaggcgtc acctccaaag caggcaaaga
      361 cagtgttggc tgcaccaatt ctagaagtaa gctctccaag ttcagactcc attcttgtgc
      421 agtgggaagc tgtatatatg gcaattgcat tctccgtgtc cattatgcga gccaatggct
      481 tggggagtat atggaaagag aatactacaa acacctcctt gacattcacc agtttagaag
      541 ccggaactct ctacaccata aaggcctatg catggaatgc caacagaatc cctggggatg
      601 actccacctg caatcagaga acaagtcctc gggcccctgc caacattcaa gtctctttcg
      661 atagtggagc tctgaaggca tctttttcct gggcacgggc agaaggagct ttcaattata
      721 ctgtgatggc tttgagcgac tcttcagagc tgacctgcag tacaactttc agttcctgca
      781 ccatctcttc cctccagtgt ggaactgaat acttgatttc agttttagca agtaatgatg
      841 ctggatctag caaatcatct tcagcaatga ccctgaaaac tgttgcttgt gcacccggaa
      901 gagtgacgat ccaagaagat ccccctggcc acctgtctgt ggcttggtcc agtgtagatc
      961 tgggtgacta ctatgtggtc tttgtgaaga gtgatgatgg cttggaagta cactgcaaca
     1021 catctctcac tcagtgcaac ttcttatctg agtgtggctt cacttatttt attagtgttt
     1081 ttgtctataa caaggcaggg caaagtcctt tgggtgacat attcaattat accacagctc
     1141 cctgttgtcc tagtgacatt aaccccgtgt tggtgtccag tgacagagtt gagattgtct
     1201 ggtctcctgt ccgtggtgcc gaactgtatg aaaccaaggc tgtagatggg tacaacatgg
     1261 ttgagtgcaa tgacactact cctgcgtgca ccctttcggc tctagagtgt gacaccaagt
     1321 acaacatcac agtgtattca ttcaatgaag tccgaggcag caatatgtca tgtactcccc
     1381 agttcataac cacagctcct tgcagtcctg aaataaaaaa tgtttcaagg gatgcattct
     1441 ccatgattaa tgtgcactgg cgatccacta atgatgatgc tacttacacg gtgactgccc
     1501 aaggggagaa aggactgtat cagtgcagca gcacaggaga gtcctgcacc atgcggggct
     1561 tgccctgtgg ctcagtgttc tctgtcactg ctgtggccga aacacaggca ggacggagcc
     1621 tgcccagcta cagtgtgccc ctggaaacag tgccatgctg tccaaccggt ctgacagtaa
     1681 ctcaaatcac ccagtcagta atcaacgtga gctggactat tgggagagtg gctcaaaccc
     1741 atgttgcagt tctggagtca cacactggac agtctaagtg tcacactcat caaaaccact
     1801 gcctcctagg atgcatcaca tgtggcatca attacacagt gacattaaaa gcaattagtg
     1861 ccaccgggtt gactgcagat tgctcctacc aaagttattt ctctggtgcc tgctgccctt
     1921 tgggggtgaa attatatagg ctgggcccta atggcatccg gatctactgg caagcctcca
     1981 ggggctctgc caattacagc actgacctct atggctccaa aggcattttc acgtgcaccc
     2041 cgagtgctgg cctcagtttc tgtgatgtca ctgagatacc ctgtggggat gtatacactg
     2101 tgatggtctc accagttgct aaaacaggat tgaagcttac tttctgtcca aaaaaaatat
     2161 attcagtaac ttgctctgga agtacacttg gaatggtgat ttatagaggg aagagaaatg
     2221 aagaatgaca aagtgagccc cagataaaaa caaaaacttg accaaagttg tctcatttgt
     2281 tagtgattag agatggaaaa gatctactag aatgtagaat aaaaatgcct ctaggatagg
     2341 aaaagctcct ttggccttta gaagaacaac tctgactctg cttcctgagg gcaaggtcag
     2401 gtgtgtcctc acctgcacag cagttggaga tctgctatgt gaggactctg gagagaaatg
     2461 aatccagaaa gtcccctgga cggctgctag cctgagttgg cacactgtga gaaccctgga
     2521 aacaagaaag ttctgcttag cagaaattct gagatttcac atccacacac accacagact
     2581 tcaacacatc cacttcatga gtgttttaca acagcacttg tctgcagccc cctcaggggc
     2641 tggaaatgtt cactcccaga aagtcaagcc acccacatgc agacagcact tatcccaaga
     2701 caaacctcca gcaggacttc agtataggtt ggaaagcagt agctgccagg gcaacctgag
     2761 ataacaaacg ccctcatcgc aagttaggag caaagctgag ctgcttgcag ggttcgctga
     2821 gccaaagcat caggtggcgt gacatctatg ggagcatctg ggaaagcaga gctgccagcc
     2881 tgttgctaga agggttgcag ttatgctttc tgcatgagag aagatgtcaa atggagagcc
     2941 tcaaactgtg gccgactgac atgcgtgcat cttttggggg aggaccatcc atcttattgg
     3001 ccatatcccc cactcatatt gtaattactt ttttcatctt tggaggggga aggcaatgaa
     3061 atataacata aatctctcat acctaaaaaa
//
