LOCUS       NM_001306132            7679 bp    mRNA    linear   PRI 12-NOV-2024
DEFINITION  Homo sapiens fibronectin 1 (FN1), transcript variant 11, mRNA.
ACCESSION   NM_001306132 XM_005246417
VERSION     NM_001306132.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7679)
  AUTHORS   Millapan,T., Gutierrez,A., Rosas,K., Buchegger,K., Ili,C.G. and
            Brebi,P.
  TITLE     In Silico Insights Reveal Fibronectin 1 as a Theranostic Marker in
            Gastric Cancer
  JOURNAL   Int J Mol Sci 25 (20), 11113 (2024)
   PUBMED   39456895
  REMARK    GeneRIF: In Silico Insights Reveal Fibronectin 1 as a Theranostic
            Marker in Gastric Cancer.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7679)
  AUTHORS   Skoczynski,K., Kraus,A., Daniel,C., Buttner-Herold,M., Amann,K.,
            Schiffer,M., Hermann,K., Herrnberger-Eimer,L., Tamm,E.R. and
            Buchholz,B.
  TITLE     The extracellular matrix protein fibronectin promotes metanephric
            kidney development
  JOURNAL   Pflugers Arch 476 (6), 963-974 (2024)
   PUBMED   38563997
  REMARK    GeneRIF: The extracellular matrix protein fibronectin promotes
            metanephric kidney development.
REFERENCE   3  (bases 1 to 7679)
  AUTHORS   Bhattarai,P., Gunasekaran,T.I., Belloy,M.E., Reyes-Dumeyer,D.,
            Julich,D., Tayran,H., Yilmaz,E., Flaherty,D., Turgutalp,B.,
            Sukumar,G., Alba,C., McGrath,E.M., Hupalo,D.N., Bacikova,D., Le
            Guen,Y., Lantigua,R., Medrano,M., Rivera,D., Recio,P., Nuriel,T.,
            Ertekin-Taner,N., Teich,A.F., Dickson,D.W., Holley,S., Greicius,M.,
            Dalgard,C.L., Zody,M., Mayeux,R., Kizil,C. and Vardarajan,B.N.
  TITLE     Rare genetic variation in fibronectin 1 (FN1) protects against
            APOEepsilon4 in Alzheimer's disease
  JOURNAL   Acta Neuropathol 147 (1), 70 (2024)
   PUBMED   38598053
  REMARK    GeneRIF: Rare genetic variation in fibronectin 1 (FN1) protects
            against APOEepsilon4 in Alzheimer's disease.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7679)
  AUTHORS   Sakai,T., Choo,Y.Y., Mitsuhashi,S., Ikebe,R., Jeffers,A., Idell,S.,
            Tucker,T.A. and Ikebe,M.
  TITLE     Myocardin regulates fibronectin expression and secretion from human
            pleural mesothelial cells
  JOURNAL   Am J Physiol Lung Cell Mol Physiol 326 (4), L419-L430 (2024)
   PUBMED   38349126
  REMARK    GeneRIF: Myocardin regulates fibronectin expression and secretion
            from human pleural mesothelial cells.
REFERENCE   5  (bases 1 to 7679)
  AUTHORS   England,J., McFarquhar,A. and Campeau,P.M.
  TITLE     Spondylometaphyseal Dysplasia, Corner Fracture Type
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   32200603
REFERENCE   6  (bases 1 to 7679)
  AUTHORS   Ruegg,C., Postigo,A.A., Sikorski,E.E., Butcher,E.C., Pytela,R. and
            Erle,D.J.
  TITLE     Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte
            adherence to fibronectin and VCAM-1 and in homotypic cell
            clustering
  JOURNAL   J Cell Biol 117 (1), 179-189 (1992)
   PUBMED   1372909
REFERENCE   7  (bases 1 to 7679)
  AUTHORS   Baron,M., Main,A.L., Driscoll,P.C., Mardon,H.J., Boyd,J. and
            Campbell,I.D.
  TITLE     1H NMR assignment and secondary structure of the cell adhesion type
            III module of fibronectin
  JOURNAL   Biochemistry 31 (7), 2068-2073 (1992)
   PUBMED   1311202
REFERENCE   8  (bases 1 to 7679)
  AUTHORS   Gutman,A., Yamada,K.M. and Kornblihtt,A.
  TITLE     Human fibronectin is synthesized as a pre-propolypeptide
  JOURNAL   FEBS Lett 207 (1), 145-148 (1986)
   PUBMED   3770189
REFERENCE   9  (bases 1 to 7679)
  AUTHORS   Kornblihtt,A.R., Vibe-Pedersen,K. and Baralle,F.E.
  TITLE     Isolation and characterization of cDNA clones for human and bovine
            fibronectins
  JOURNAL   Proc Natl Acad Sci U S A 80 (11), 3218-3222 (1983)
   PUBMED   6304699
REFERENCE   10 (bases 1 to 7679)
  AUTHORS   Zucker,M.B., Mosesson,M.W., Broekman,M.J. and Kaplan,K.L.
  TITLE     Release of platelet fibronectin (cold-insoluble globulin) from
            alpha granules induced by thrombin or collagen; lack of requirement
            for plasma fibronectin in ADP-induced platelet aggregation
  JOURNAL   Blood 54 (1), 8-12 (1979)
   PUBMED   444675
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC012462.5 and AC073284.5.
            
            On Apr 15, 2020 this sequence version replaced NM_001306132.1.
            
            Summary: This gene encodes fibronectin, a glycoprotein present in a
            soluble dimeric form in plasma, and in a dimeric or multimeric form
            at the cell surface and in extracellular matrix. The encoded
            preproprotein is proteolytically processed to generate the mature
            protein. Fibronectin is involved in cell adhesion and migration
            processes including embryogenesis, wound healing, blood
            coagulation, host defense, and metastasis. The gene has three
            regions subject to alternative splicing, with the potential to
            produce 20 different transcript variants, at least one of which
            encodes an isoform that undergoes proteolytic processing. The
            full-length nature of some variants has not been determined.
            [provided by RefSeq, Jan 2016].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CR749317.1, BC143754.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-414               AC012462.5         70138-70551         c
            415-543             AC012462.5         69179-69307         c
            544-681             AC012462.5         67807-67944         c
            682-813             AC012462.5         66316-66447         c
            814-951             AC012462.5         65198-65335         c
            952-1110            AC012462.5         62663-62821         c
            1111-1302           AC012462.5         59577-59768         c
            1303-1482           AC012462.5         58629-58808         c
            1483-1659           AC012462.5         57833-58009         c
            1660-1812           AC012462.5         56574-56726         c
            1813-1941           AC012462.5         55156-55284         c
            1942-2085           AC012462.5         53725-53868         c
            2086-2207           AC012462.5         49320-49441         c
            2208-2388           AC012462.5         44417-44597         c
            2389-2565           AC012462.5         44046-44222         c
            2566-2694           AC012462.5         42781-42909         c
            2695-2784           AC012462.5         42591-42680         c
            2785-2979           AC012462.5         41610-41804         c
            2980-3252           AC012462.5         40721-40993         c
            3253-3519           AC012462.5         38872-39138         c
            3520-3614           AC012462.5         33740-33834         c
            3615-3783           AC012462.5         32163-32331         c
            3784-3870           AC012462.5         31620-31706         c
            3871-4062           AC012462.5         29011-29202         c
            4063-4245           AC012462.5         26115-26297         c
            4246-4335           AC012462.5         22695-22784         c
            4336-4605           AC012462.5         21172-21441         c
            4606-4722           AC012462.5         19343-19459         c
            4723-4887           AC012462.5         18503-18667         c
            4888-5043           AC012462.5         17811-17966         c
            5044-5157           AC012462.5         16695-16808         c
            5158-5345           AC012462.5         13613-13800         c
            5346-5433           AC012462.5         12658-12745         c
            5434-5610           AC012462.5         10981-11157         c
            5611-5700           AC012462.5         10112-10201         c
            5701-5880           AC012462.5         9697-9876           c
            5881-5970           AC012462.5         7805-7894           c
            5971-6162           AC012462.5         6592-6783           c
            6163-6269           AC012462.5         6392-6498           c
            6270-6408           AC012462.5         4777-4915           c
            6409-6573           AC012462.5         2346-2510           c
            6574-6686           AC012462.5         1-113               c
            6687-6699           AC073284.5         94615-94627         c
            6700-6806           AC073284.5         93989-94095         c
            6807-6917           AC073284.5         91079-91189         c
            6918-7679           AC073284.5         89975-90736         c
FEATURES             Location/Qualifiers
     source          1..7679
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q35"
     gene            1..7679
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /note="fibronectin 1"
                     /db_xref="GeneID:2335"
                     /db_xref="HGNC:HGNC:3778"
                     /db_xref="MIM:135600"
     exon            1..414
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     CDS             267..6989
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /note="isoform 11 precursor is encoded by transcript
                     variant 11; cold-insoluble globulin; migration-stimulating
                     factor; lnc-ABCA12-8; epididymis secretory sperm binding
                     protein"
                     /codon_start=1
                     /product="fibronectin isoform 11 precursor"
                     /protein_id="NP_001293061.2"
                     /db_xref="CCDS:CCDS77522.1"
                     /db_xref="GeneID:2335"
                     /db_xref="HGNC:HGNC:3778"
                     /db_xref="MIM:135600"
                     /translation="MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVA
                     VSQSKPGCYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYT
                     GNTYRVGDTYERPKDSMIWDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHET
                     GGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGE
                     GSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSV
                     QTTSSGSGPFTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCT
                     CLGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNY
                     EQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQ
                     NYDADQKFGFCPMAAHEEICTTNEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTC
                     IAYSQLRDQCIVDDITYNVNDTFHKRHEEGHMLNCTCFGQGRGRWKCDPVDQCQDSET
                     GTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPN
                     SHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLI
                     SIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW
                     VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE
                     QSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTEL
                     NLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ
                     FVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT
                     YYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLT
                     VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG
                     SSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPG
                     VEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT
                     GYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT
                     IIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
                     NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW
                     IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE
                     SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF
                     TVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTD
                     VQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVV
                     SVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTP
                     KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP
                     PRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ
                     PGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG
                     YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK
                     TVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRP
                     RPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGL
                     TRGATYNVIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDE
                     WERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTC
                     LGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRP
                     GGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE"
     exon            415..543
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            544..681
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            682..813
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            814..951
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1110
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..1302
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..1482
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            1483..1659
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            1660..1812
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            1813..1941
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            1942..2085
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            2086..2207
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            2208..2388
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            2389..2565
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            2566..2694
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            2695..2784
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            2785..2979
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            2980..3252
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            3253..3519
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            3520..3614
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            3615..3783
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            3784..3870
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            3871..4062
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            4063..4245
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            4246..4335
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            4336..4605
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            4606..4722
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            4723..4887
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            4888..5043
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            5044..5157
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            5158..5345
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            5346..5433
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            5434..5610
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            5611..5700
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            5701..5880
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            5881..5970
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            5971..6162
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            6163..6269
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            6270..6408
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            6409..6573
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            6574..6699
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            6700..6806
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            6807..6917
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     exon            6918..7679
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7660..7665
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /note="hexamer: AATAAA"
     polyA_site      7679
                     /gene="FN1"
                     /gene_synonym="CIG; ED-B; FINC; FN; FNZ; GFND; GFND2;
                     LETS; MSF; SMDCF"
                     /note="major polyA site"
ORIGIN      
        1 gcccgcgccg gctgtgctgc acagggggag gagagggaac cccaggcgcg agcgggaaga
       61 ggggacctgc agccacaact tctctggtcc tctgcatccc ttctgtccct ccacccgtcc
      121 ccttccccac cctctggccc ccaccttctt ggaggcgaca acccccggga ggcattagaa
      181 gggatttttc ccgcaggttg cgaagggaag caaacttggt ggcaacttgc ctcccggtgc
      241 gggcgtctct cccccaccgt ctcaacatgc ttaggggtcc ggggcccggg ctgctgctgc
      301 tggccgtcca gtgcctgggg acagcggtgc cctccacggg agcctcgaag agcaagaggc
      361 aggctcagca aatggttcag ccccagtccc cggtggctgt cagtcaaagc aagcccggtt
      421 gttatgacaa tggaaaacac tatcagataa atcaacagtg ggagcggacc tacctaggca
      481 atgcgttggt ttgtacttgt tatggaggaa gccgaggttt taactgcgag agtaaacctg
      541 aagctgaaga gacttgcttt gacaagtaca ctgggaacac ttaccgagtg ggtgacactt
      601 atgagcgtcc taaagactcc atgatctggg actgtacctg catcggggct gggcgaggga
      661 gaataagctg taccatcgca aaccgctgcc atgaaggggg tcagtcctac aagattggtg
      721 acacctggag gagaccacat gagactggtg gttacatgtt agagtgtgtg tgtcttggta
      781 atggaaaagg agaatggacc tgcaagccca tagctgagaa gtgttttgat catgctgctg
      841 ggacttccta tgtggtcgga gaaacgtggg agaagcccta ccaaggctgg atgatggtag
      901 attgtacttg cctgggagaa ggcagcggac gcatcacttg cacttctaga aatagatgca
      961 acgatcagga cacaaggaca tcctatagaa ttggagacac ctggagcaag aaggataatc
     1021 gaggaaacct gctccagtgc atctgcacag gcaacggccg aggagagtgg aagtgtgaga
     1081 ggcacacctc tgtgcagacc acatcgagcg gatctggccc cttcaccgat gttcgtgcag
     1141 ctgtttacca accgcagcct cacccccagc ctcctcccta tggccactgt gtcacagaca
     1201 gtggtgtggt ctactctgtg gggatgcagt ggctgaagac acaaggaaat aagcaaatgc
     1261 tttgcacgtg cctgggcaac ggagtcagct gccaagagac agctgtaacc cagacttacg
     1321 gtggcaactc aaatggagag ccatgtgtct taccattcac ctacaatggc aggacgttct
     1381 actcctgcac cacagaaggg cgacaggacg gacatctttg gtgcagcaca acttcgaatt
     1441 atgagcagga ccagaaatac tctttctgca cagaccacac tgttttggtt cagactcgag
     1501 gaggaaattc caatggtgcc ttgtgccact tccccttcct atacaacaac cacaattaca
     1561 ctgattgcac ttctgagggc agaagagaca acatgaagtg gtgtgggacc acacagaact
     1621 atgatgccga ccagaagttt gggttctgcc ccatggctgc ccacgaggaa atctgcacaa
     1681 ccaatgaagg ggtcatgtac cgcattggag atcagtggga taagcagcat gacatgggtc
     1741 acatgatgag gtgcacgtgt gttgggaatg gtcgtgggga atggacatgc attgcctact
     1801 cgcagcttcg agatcagtgc attgttgatg acatcactta caatgtgaac gacacattcc
     1861 acaagcgtca tgaagagggg cacatgctga actgtacatg cttcggtcag ggtcggggca
     1921 ggtggaagtg tgatcccgtc gaccaatgcc aggattcaga gactgggacg ttttatcaaa
     1981 ttggagattc atgggagaag tatgtgcatg gtgtcagata ccagtgctac tgctatggcc
     2041 gtggcattgg ggagtggcat tgccaacctt tacagaccta tccaagctca agtggtcctg
     2101 tcgaagtatt tatcactgag actccgagtc agcccaactc ccaccccatc cagtggaatg
     2161 caccacagcc atctcacatt tccaagtaca ttctcaggtg gagacctaaa aattctgtag
     2221 gccgttggaa ggaagctacc ataccaggcc acttaaactc ctacaccatc aaaggcctga
     2281 agcctggtgt ggtatacgag ggccagctca tcagcatcca gcagtacggc caccaagaag
     2341 tgactcgctt tgacttcacc accaccagca ccagcacacc tgtgaccagc aacaccgtga
     2401 caggagagac gactcccttt tctcctcttg tggccacttc tgaatctgtg accgaaatca
     2461 cagccagtag ctttgtggtc tcctgggtct cagcttccga caccgtgtcg ggattccggg
     2521 tggaatatga gctgagtgag gagggagatg agccacagta cctggatctt ccaagcacag
     2581 ccacttctgt gaacatccct gacctgcttc ctggccgaaa atacattgta aatgtctatc
     2641 agatatctga ggatggggag cagagtttga tcctgtctac ttcacaaaca acagcgcctg
     2701 atgcccctcc tgacacgact gtggaccaag ttgatgacac ctcaattgtt gttcgctgga
     2761 gcagacccca ggctcccatc acagggtaca gaatagtcta ttcgccatca gtagaaggta
     2821 gcagcacaga actcaacctt cctgaaactg caaactccgt caccctcagt gacttgcaac
     2881 ctggtgttca gtataacatc actatctatg ctgtggaaga aaatcaagaa agtacacctg
     2941 ttgtcattca acaagaaacc actggcaccc cacgctcaga tacagtgccc tctcccaggg
     3001 acctgcagtt tgtggaagtg acagacgtga aggtcaccat catgtggaca ccgcctgaga
     3061 gtgcagtgac cggctaccgt gtggatgtga tccccgtcaa cctgcctggc gagcacgggc
     3121 agaggctgcc catcagcagg aacacctttg cagaagtcac cgggctgtcc cctggggtca
     3181 cctattactt caaagtcttt gcagtgagcc atgggaggga gagcaagcct ctgactgctc
     3241 aacagacaac caaactggat gctcccacta acctccagtt tgtcaatgaa actgattcta
     3301 ctgtcctggt gagatggact ccacctcggg cccagataac aggataccga ctgaccgtgg
     3361 gccttacccg aagaggacag cccaggcagt acaatgtggg tccctctgtc tccaagtacc
     3421 cactgaggaa tctgcagcct gcatctgagt acaccgtatc cctcgtggcc ataaagggca
     3481 accaagagag ccccaaagcc actggagtct ttaccacact gcagcctggg agctctattc
     3541 caccttacaa caccgaggtg actgagacca ccattgtgat cacatggacg cctgctccaa
     3601 gaattggttt taagctgggt gtacgaccaa gccagggagg agaggcacca cgagaagtga
     3661 cttcagactc aggaagcatc gttgtgtccg gcttgactcc aggagtagaa tacgtctaca
     3721 ccatccaagt cctgagagat ggacaggaaa gagatgcgcc aattgtaaac aaagtggtga
     3781 caccattgtc tccaccaaca aacttgcatc tggaggcaaa ccctgacact ggagtgctca
     3841 cagtctcctg ggagaggagc accaccccag acattactgg ttatagaatt accacaaccc
     3901 ctacaaacgg ccagcaggga aattctttgg aagaagtggt ccatgctgat cagagctcct
     3961 gcacttttga taacctgagt cccggcctgg agtacaatgt cagtgtttac actgtcaagg
     4021 atgacaagga aagtgtccct atctctgata ccatcatccc agctgttcct cctcccactg
     4081 acctgcgatt caccaacatt ggtccagaca ccatgcgtgt cacctgggct ccacccccat
     4141 ccattgattt aaccaacttc ctggtgcgtt actcacctgt gaaaaatgag gaagatgttg
     4201 cagagttgtc aatttctcct tcagacaatg cagtggtctt aacaaatctc ctgcctggta
     4261 cagaatatgt agtgagtgtc tccagtgtct acgaacaaca tgagagcaca cctcttagag
     4321 gaagacagaa aacaggtctt gattccccaa ctggcattga cttttctgat attactgcca
     4381 actcttttac tgtgcactgg attgctcctc gagccaccat cactggctac aggatccgcc
     4441 atcatcccga gcacttcagt gggagacctc gagaagatcg ggtgccccac tctcggaatt
     4501 ccatcaccct caccaacctc actccaggca cagagtatgt ggtcagcatc gttgctctta
     4561 atggcagaga ggaaagtccc ttattgattg gccaacaatc aacagtttct gatgttccga
     4621 gggacctgga agttgttgct gcgaccccca ccagcctact gatcagctgg gatgctcctg
     4681 ctgtcacagt gagatattac aggatcactt acggagagac aggaggaaat agccctgtcc
     4741 aggagttcac tgtgcctggg agcaagtcta cagctaccat cagcggcctt aaacctggag
     4801 ttgattatac catcactgtg tatgctgtca ctggccgtgg agacagcccc gcaagcagca
     4861 agccaatttc cattaattac cgaacagaaa ttgacaaacc atcccagatg caagtgaccg
     4921 atgttcagga caacagcatt agtgtcaagt ggctgccttc aagttcccct gttactggtt
     4981 acagagtaac caccactccc aaaaatggac caggaccaac aaaaactaaa actgcaggtc
     5041 cagatcaaac agaaatgact attgaaggct tgcagcccac agtggagtat gtggttagtg
     5101 tctatgctca gaatccaagc ggagagagtc agcctctggt tcagactgca gtaaccacta
     5161 ttcctgcacc aactgacctg aagttcactc aggtcacacc cacaagcctg agcgcccagt
     5221 ggacaccacc caatgttcag ctcactggat atcgagtgcg ggtgaccccc aaggagaaga
     5281 ccggaccaat gaaagaaatc aaccttgctc ctgacagctc atccgtggtt gtatcaggac
     5341 ttatggtggc caccaaatat gaagtgagtg tctatgctct taaggacact ttgacaagca
     5401 gaccagctca gggagttgtc accactctgg agaatgtcag cccaccaaga agggctcgtg
     5461 tgacagatgc tactgagacc accatcacca ttagctggag aaccaagact gagacgatca
     5521 ctggcttcca agttgatgcc gttccagcca atggccagac tccaatccag agaaccatca
     5581 agccagatgt cagaagctac accatcacag gtttacaacc aggcactgac tacaagatct
     5641 acctgtacac cttgaatgac aatgctcgga gctcccctgt ggtcatcgac gcctccactg
     5701 ccattgatgc accatccaac ctgcgtttcc tggccaccac acccaattcc ttgctggtat
     5761 catggcagcc gccacgtgcc aggattaccg gctacatcat caagtatgag aagcctgggt
     5821 ctcctcccag agaagtggtc cctcggcccc gccctggtgt cacagaggct actattactg
     5881 gcctggaacc gggaaccgaa tatacaattt atgtcattgc cctgaagaat aatcagaaga
     5941 gcgagcccct gattggaagg aaaaagacag ttcaaaagac ccctttcgtc acccaccctg
     6001 ggtatgacac tggaaatggt attcagcttc ctggcacttc tggtcagcaa cccagtgttg
     6061 ggcaacaaat gatctttgag gaacatggtt ttaggcggac cacaccgccc acaacggcca
     6121 cccccataag gcataggcca agaccatacc cgccgaatgt aggacaagaa gctctctctc
     6181 agacaaccat ctcatgggcc ccattccagg acacttctga gtacatcatt tcatgtcatc
     6241 ctgttggcac tgatgaagaa cccttacagt tcagggttcc tggaacttct accagtgcca
     6301 ctctgacagg cctcaccaga ggtgccacct acaacgtcat agtggaggca ctgaaagacc
     6361 agcagaggca taaggttcgg gaagaggttg ttaccgtggg caactctgtc aacgaaggct
     6421 tgaaccaacc tacggatgac tcgtgctttg acccctacac agtttcccat tatgccgttg
     6481 gagatgagtg ggaacgaatg tctgaatcag gctttaaact gttgtgccag tgcttaggct
     6541 ttggaagtgg tcatttcaga tgtgattcat ctagatggtg ccatgacaat ggtgtgaact
     6601 acaagattgg agagaagtgg gaccgtcagg gagaaaatgg ccagatgatg agctgcacat
     6661 gtcttgggaa cggaaaagga gaattcaagt gtgaccctca tgaggcaacg tgttatgatg
     6721 atgggaagac ataccacgta ggagaacagt ggcagaagga atatctcggt gccatttgct
     6781 cctgcacatg ctttggaggc cagcggggct ggcgctgtga caactgccgc agacctgggg
     6841 gtgaacccag tcccgaaggc actactggcc agtcctacaa ccagtattct cagagatacc
     6901 atcagagaac aaacactaat gttaattgcc caattgagtg cttcatgcct ttagatgtac
     6961 aggctgacag agaagattcc cgagagtaaa tcatctttcc aatccagagg aacaagcatg
     7021 tctctctgcc aagatccatc taaactggag tgatgttagc agacccagct tagagttctt
     7081 ctttctttct taagcccttt gctctggagg aagttctcca gcttcagctc aactcacagc
     7141 ttctccaagc atcaccctgg gagtttcctg agggttttct cataaatgag ggctgcacat
     7201 tgcctgttct gcttcgaagt attcaatacc gctcagtatt ttaaatgaag tgattctaag
     7261 atttggtttg ggatcaatag gaaagcatat gcagccaacc aagatgcaaa tgttttgaaa
     7321 tgatatgacc aaaattttaa gtaggaaagt cacccaaaca cttctgcttt cacttaagtg
     7381 tctggcccgc aatactgtag gaacaagcat gatcttgtta ctgtgatatt ttaaatatcc
     7441 acagtactca ctttttccaa atgatcctag taattgccta gaaatatctt tctcttacct
     7501 gttatttatc aatttttccc agtattttta tacggaaaaa attgtattga aaacacttag
     7561 tatgcagttg ataagaggaa tttggtataa ttatggtggg tgattatttt ttatactgta
     7621 tgtgccaaag ctttactact gtggaaagac aactgtttta ataaaagatt tacattcca
//
