LOCUS       NM_005892               4003 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens formin like 1 (FMNL1), transcript variant 1, mRNA.
ACCESSION   NM_005892
VERSION     NM_005892.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4003)
  AUTHORS   Ma,G., Zhang,B., Fu,S., Lu,J., Zhang,L., Shang,P. and Yue,Z.
  TITLE     Formin-related protein 1 facilitates proliferation and aggressive
            phenotype of clear cell renal cell carcinoma through MAPK/MMP2
            pathway
  JOURNAL   Mol Cell Probes 71, 101921 (2023)
   PUBMED   37454877
  REMARK    GeneRIF: Formin-related protein 1 facilitates proliferation and
            aggressive phenotype of clear cell renal cell carcinoma through
            MAPK/MMP2 pathway.
REFERENCE   2  (bases 1 to 4003)
  AUTHORS   Walch,P., Selkrig,J., Knodler,L.A., Rettel,M., Stein,F.,
            Fernandez,K., Vieitez,C., Potel,C.M., Scholzen,K., Geyer,M.,
            Rottner,K., Steele-Mortimer,O., Savitski,M.M., Holden,D.W. and
            Typas,A.
  TITLE     Global mapping of Salmonella enterica-host protein-protein
            interactions during infection
  JOURNAL   Cell Host Microbe 29 (8), 1316-1332 (2021)
   PUBMED   34237247
REFERENCE   3  (bases 1 to 4003)
  AUTHORS   Higa,N., Shinsato,Y., Kamil,M., Hirano,T., Takajo,T., Shimokawa,M.,
            Minami,K., Yamamoto,M., Kawahara,K., Yonezawa,H., Hirano,H.,
            Furukawa,T., Yoshimoto,K. and Arita,K.
  TITLE     Formin-like 1 (FMNL1) Is Associated with Glioblastoma Multiforme
            Mesenchymal Subtype and Independently Predicts Poor Prognosis
  JOURNAL   Int J Mol Sci 20 (24), 6355 (2019)
   PUBMED   31861134
  REMARK    GeneRIF: Formin-like 1 protein (FMNL1) is a promising therapeutic
            target for glioblastoma multiforme (GBM) progression.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4003)
  AUTHORS   Cui,F., Ji,Y., Wang,M., Gao,F., Li,Y. and Li,X.
  TITLE     miR-143 inhibits proliferation and metastasis of nasopharyngeal
            carcinoma cells via targeting FMNL1 based on clinical and
            radiologic findings
  JOURNAL   J Cell Biochem 120 (10), 16427-16434 (2019)
   PUBMED   31001854
  REMARK    GeneRIF: miR-143 inhibits proliferation and metastasis of
            nasopharyngeal carcinoma cells via targeting FMNL1 based on
            clinical and radiologic findings.
REFERENCE   5  (bases 1 to 4003)
  AUTHORS   Yang,X.Y., Liao,J.J. and Xue,W.R.
  TITLE     FMNL1 down-regulation suppresses bone metastasis through reducing
            TGF-beta1 expression in non-small cell lung cancer (NSCLC)
  JOURNAL   Biomed Pharmacother 117, 109126 (2019)
   PUBMED   31387165
  REMARK    GeneRIF: Suppressing FMNL1 expression could inhibit bone metastasis
            in NSCLC through blocking TGF-beta1 signaling.
REFERENCE   6  (bases 1 to 4003)
  AUTHORS   Katoh,M. and Katoh,M.
  TITLE     Identification and characterization of human FMNL1, FMNL2 and FMNL3
            genes in silico
  JOURNAL   Int J Oncol 22 (5), 1161-1168 (2003)
   PUBMED   12684686
REFERENCE   7  (bases 1 to 4003)
  AUTHORS   Katoh,M. and Katoh,M.
  TITLE     Identification and characterization of human DAAM2 gene in silico
  JOURNAL   Int J Oncol 22 (4), 915-920 (2003)
   PUBMED   12632087
REFERENCE   8  (bases 1 to 4003)
  AUTHORS   Yayoshi-Yamamoto,S., Taniuchi,I. and Watanabe,T.
  TITLE     FRL, a novel formin-related protein, binds to Rac and regulates
            cell motility and survival of macrophages
  JOURNAL   Mol Cell Biol 20 (18), 6872-6881 (2000)
   PUBMED   10958683
REFERENCE   9  (bases 1 to 4003)
  AUTHORS   Kennerson,M.L., Nassif,N.T. and Nicholson,G.A.
  TITLE     Genomic structure and physical mapping of C17orf1: a gene
            associated with the proximal element of the CMT1A-REP binary repeat
  JOURNAL   Genomics 53 (1), 110-112 (1998)
   PUBMED   9787083
REFERENCE   10 (bases 1 to 4003)
  AUTHORS   Aronsson,F.C., Magnusson,P., Andersson,B., Karsten,S.L.,
            Shibasaki,Y., Lendon,C.L., Goate,A.M. and Brookes,A.J.
  TITLE     The NIK protein kinase and C17orf1 genes: chromosomal mapping, gene
            structures and mutational screening in frontotemporal dementia and
            parkinsonism linked to chromosome 17
  JOURNAL   Hum Genet 103 (3), 340-345 (1998)
   PUBMED   9799091
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC008105.32.
            
            On Nov 23, 2018 this sequence version replaced NM_005892.3.
            
            Summary: This gene encodes a formin-related protein. Formin-related
            proteins have been implicated in morphogenesis, cytokinesis, and
            cell polarity. An alternative splice variant has been described but
            its full length sequence has not been determined. [provided by
            RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY278319.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000331495.8/ ENSP00000329219.2
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-369               AC008105.32        53671-54039
            370-453             AC008105.32        62390-62473
            454-567             AC008105.32        64153-64266
            568-641             AC008105.32        65010-65083
            642-725             AC008105.32        65434-65517
            726-854             AC008105.32        65858-65986
            855-963             AC008105.32        67922-68030
            964-1040            AC008105.32        69067-69143
            1041-1134           AC008105.32        69332-69425
            1135-1209           AC008105.32        70350-70424
            1210-1320           AC008105.32        70741-70851
            1321-1470           AC008105.32        72262-72411
            1471-1572           AC008105.32        72915-73016
            1573-1825           AC008105.32        73168-73420
            1826-2125           AC008105.32        73633-73932
            2126-2250           AC008105.32        74127-74251
            2251-2453           AC008105.32        74904-75106
            2454-2688           AC008105.32        75577-75811
            2689-2757           AC008105.32        75962-76030
            2758-2838           AC008105.32        76605-76685
            2839-2968           AC008105.32        76765-76894
            2969-3132           AC008105.32        77039-77202
            3133-3234           AC008105.32        77418-77519
            3235-3330           AC008105.32        77664-77759
            3331-3451           AC008105.32        77996-78116
            3452-3551           AC008105.32        78291-78390
            3552-4003           AC008105.32        78653-79104
FEATURES             Location/Qualifiers
     source          1..4003
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.31"
     gene            1..4003
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /note="formin like 1"
                     /db_xref="GeneID:752"
                     /db_xref="HGNC:HGNC:1212"
                     /db_xref="MIM:604656"
     exon            1..369
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     CDS             241..3543
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /note="isoform 1 is encoded by transcript variant 1;
                     formin-like protein 1; leukocyte formin; CLL-associated
                     antigen KW-13"
                     /codon_start=1
                     /product="formin-like protein 1 isoform 1"
                     /protein_id="NP_005883.3"
                     /db_xref="CCDS:CCDS11497.1"
                     /db_xref="GeneID:752"
                     /db_xref="HGNC:HGNC:1212"
                     /db_xref="MIM:604656"
                     /translation="MGNAAGSAEQPAGPAAPPPKQPAPPKQPMPAAGELEERFNRALN
                     CMNLPPDKVQLLSQYDNEKKWELICDQERFQVKNPPAAYIQKLKSYVDTGGVSRKVAA
                     DWMSNLGFKRRVQESTQVLRELETSLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQCS
                     VTYDMESTDNGASNSEKNKPLEQSVEDLSKGPPSSVPKSRHLTIKLTPAHSRKALRNS
                     RIVSQKDDVHVCIMCLRAIMNYQSGFSLVMNHPACVNEIALSLNNKNPRTKALVLELL
                     AAVCLVRGGHDIILAAFDNFKEVCGEQHRFEKLMEYFRNEDSNIDFMVACMQFINIVV
                     HSVENMNFRVFLQYEFTHLGLDLYLERLRLTESDKLQVQIQAYLDNIFDVGALLEDTE
                     TKNAVLEHMEELQEQVALLTERLRDAENESMAKIAELEKQLSQARKELETLRERFSES
                     TAMGPSRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAV
                     ATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAP
                     PLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDS
                     ELGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMSDFEEQFK
                     TKSQGPSLDLSALKSKAAQKAPSKATLIEANRAKNLAITLRKGNLGAERICQAIEAYD
                     LQALGLDFLELLMRFLPTEYERSLITRFEREQRPMEELSEEDRFMLCFSRIPRLPERM
                     TTLTFLGNFPDTAQLLMPQLNAIIAASMSIKSSDKLRQILEIVLAFGNYMNSSKRGAA
                     YGFRLQSLDALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGSVSLDS
                     VLADVRSLQRGLELTQREFVRQDDCMVLKEFLRANSPTMDKLLADSKTAQEAFESVVE
                     YFGENPKTTSPGLFFSLFSRFIKAYKKAEQEVEQWKKEAAAQEAGADTPGKGEPPAPK
                     SPPKARRPQMDLISELKRRQQKEPLIYESDRDGAIEDIITVIKTVPFTARTGKRTSRL
                     LCEASLGEEMPL"
     exon            370..453
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            454..567
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            568..641
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            642..725
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            726..854
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            855..963
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1040
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1041..1134
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1209
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1210..1320
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1321..1470
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1471..1572
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1573..1825
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1826..2125
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            2126..2250
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            2251..2453
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            2454..2688
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            2689..2757
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            2758..2838
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            2839..2968
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            2969..3132
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            3133..3234
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            3235..3330
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            3331..3451
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            3452..3551
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     exon            3552..4003
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3985..3990
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /note="hexamer: AATAAA"
     polyA_site      4003
                     /gene="FMNL1"
                     /gene_synonym="C17orf1; C17orf1B; FHOD4; FMNL; KW-13"
                     /note="major polyA site"
ORIGIN      
        1 gacttcctcc cccaaccctg cagctcgccg cccggtccca cggacggggc cgccccgatg
       61 ggacgccgcg ctccggcccc tgcgcgccgc tgagccgagc gccccccgct gccgagaccc
      121 ccgccgccac cgccagccgc tgccccctcg cccccgcccg ggccgggagc ctcgtccccg
      181 tcccccggaa agctggattt ccgaggctgg aggcgcctgg ccggctgggt ggggaccacc
      241 atgggcaacg cggccggcag cgccgagcag cccgcgggcc ccgccgcgcc gccccccaag
      301 cagcccgcgc ctcccaagca gccgatgccc gcggccggag agctggagga gaggttcaac
      361 cgcgccctga actgcatgaa cttgccccca gacaaggtcc agctgctgag ccagtatgac
      421 aacgagaaga agtgggagct catctgtgat caggagcggt ttcaagtcaa gaatcccccc
      481 gcagcctaca tccagaagct gaagagctat gtggatactg gtggggtcag ccgaaaggta
      541 gcagctgatt ggatgtccaa cctggggttt aagaggcgag ttcaggagtc cacgcaggtg
      601 ctacgggagc tggagacctc cctgaggacc aaccacattg ggtgggtgca ggagttcctc
      661 aatgaagaga accgtggcct ggatgtgctg ctcgagtacc tggcctttgc ccagtgctct
      721 gtcacgtatg acatggagag cacagacaac ggggcttcca actcagagaa aaacaagccc
      781 ctggagcagt ctgtggaaga cctcagcaag ggtccaccct cctccgtgcc caaaagccgc
      841 cacctgacca tcaagctgac cccagcccac agcaggaagg ccctgcggaa ttcccgcatc
      901 gtcagccaga aggacgacgt ccacgtctgt attatgtgcc tacgcgccat catgaactac
      961 cagtctggct tcagccttgt catgaaccac ccagcctgtg tcaatgagat tgctctgagc
     1021 ctcaacaaca agaaccccag aaccaaggct ctggtgctgg agctgctggc ggccgtgtgc
     1081 ttggtgcggg gaggacatga catcatcctt gcagcctttg acaacttcaa ggaggtgtgt
     1141 ggggagcagc accgctttga aaagctgatg gaatatttcc ggaatgagga cagcaacatc
     1201 gacttcatgg tggcctgcat gcagttcatc aacattgtgg tacattcggt ggagaacatg
     1261 aacttccgtg tcttcctgca atatgagttc acccacttgg gcctggacct gtacttggag
     1321 aggcttcggc tcaccgagag tgacaagctg caggtgcaga tccaggcgta cctggacaat
     1381 atttttgatg tgggggcgct gctggaggac acagagacca agaacgctgt gctggagcac
     1441 atggaggaac tgcaggagca agtggcgctg ctgacagagc ggcttcggga cgcggagaac
     1501 gaatccatgg ccaagattgc agaactggaa aaacagctaa gccaggcgcg caaggagttg
     1561 gagaccctgc gggagcgctt cagcgaatcg accgccatgg ggccctccag gcgtccccca
     1621 gagcctgaga aagcgcctcc cgctgccccg acgcggccct cggccctgga gctgaaggtg
     1681 gaggagctgg aggagaaggg gttaatccgt attctgcggg ggccggggga tgctgtctcc
     1741 atcgagatcc tccccgtcgc tgtggcaact ccgagcggcg gtgatgctcc gactccgggg
     1801 gtgccgaccg gctcccccag cccagatctc gcacctgcag cagagccggc tcccggagca
     1861 gcgccaccgc cgccgccccc actgcccggc ctcccctccc cgcaggaagc cccgccctct
     1921 gcgcccccac aggccccgcc tctccctggc agcccggagc ccccgcctgc gccgccgctg
     1981 cccggagacc tgccgccccc acccccgcca ccgccaccac ctccgggcac tgacgggccg
     2041 gtgcctccgc cgccgccgcc gccgccgccg cctcccggag gtcctcctga tgccctagga
     2101 agacgcgact cagaattggg cccaggagtg aaggccaaga agcccatcca gactaagttc
     2161 cgaatgccac tcttgaactg ggtggcactg aaacccagcc agatcaccgg cactgtcttc
     2221 acagagctca atgatgagaa ggtgctgcag gagctagaca tgagtgattt tgaggaacag
     2281 ttcaagacca agtcccaagg ccccagcctg gacctcagcg ctctcaagag taaggcagcc
     2341 cagaaggccc ccagcaaggc gacactcatt gaggccaacc gggccaagaa cttggccatc
     2401 accctgcgga agggcaacct gggggccgag cgcatctgcc aagccattga ggcgtacgac
     2461 ctgcaggctc tgggcctgga cttcctggag ctgctgatgc gcttcctgcc cacagagtat
     2521 gagcgcagcc tcatcacccg ctttgagcgg gagcagcggc caatggagga gctgtcagag
     2581 gaggaccgct tcatgctatg cttcagccgc atcccgcgcc tgccggagcg catgaccaca
     2641 ctcaccttcc tgggcaactt cccggacaca gcccagctgc tcatgccgca actgaatgcc
     2701 atcattgcag cctcaatgtc catcaagtcc tctgacaaac tccgccagat cctggagatt
     2761 gtcctggcct ttggcaacta catgaacagt agcaagcgtg gggcagccta tggcttccgg
     2821 ctccagagcc tggatgcgct gttggagatg aagtcgactg atcgcaagca gacgctgctg
     2881 cactacctgg tgaaggtcat tgctgagaag tacccgcaac tcacaggctt ccacagcgac
     2941 ctgcacttcc tggacaaggc gggctcagtg tccctggaca gtgtcctggc ggacgtgcgc
     3001 tccctgcagc gaggcctaga gttgacacag agagagtttg tgcggcagga tgactgcatg
     3061 gtgctcaagg agttcctgag ggccaactcg cccaccatgg acaagctgct ggcagacagc
     3121 aagacggctc aggaggcctt tgagtctgtg gtggagtact tcggagagaa ccccaagacc
     3181 acatccccag gcctgttctt ctccctcttt agccgcttca ttaaggccta caagaaagct
     3241 gagcaggagg tggaacagtg gaaaaaagaa gccgctgccc aggaggcagg cgctgatacc
     3301 ccgggcaaag gggagccccc agcacccaag tcaccgccaa aggcccggcg gccacagatg
     3361 gacctcatct ctgagctgaa acggaggcag cagaaggagc cactcattta tgagagcgac
     3421 cgtgatgggg ccattgaaga catcatcaca gtgatcaaga cggtgccctt cacggcccgc
     3481 accggcaagc ggacatcccg gctcctctgt gaggccagcc tgggagaaga gatgcccctc
     3541 tagcccctca gatctgcgga accagcccta catccgcgca gacacaggcc gccgcagtgc
     3601 ccgtcggcgt cccccgggcc ccccactgca ggtcacctcc gacctctcgc tgtagccgct
     3661 atttctgcag gtggattctg caggggtgtg gggccgtgga caggctgagg ctcaaggaag
     3721 gtggtcctca gctcggctgg ccgggcagcc cctcctccgc tgtggcccgc ctcaaacggg
     3781 ctggtgcatc ctcctcttgg ccacagaggg cagcatcgcc cgccccttcc cccaaatgct
     3841 gcttgcagca cccaccctaa agccccctcc aaatagccat acttagcctc agcaggagcc
     3901 tggcctgtaa cttataaagt gcacctcgcc cccgcaagcc ccagccccga ggaccgtcca
     3961 tggaccttat ttttatatga gattaataaa gatgtttgca aaa
//
