LOCUS       NM_138439                990 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens FLYWCH family member 2 (FLYWCH2), transcript variant
            1, mRNA.
ACCESSION   NM_138439
VERSION     NM_138439.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 990)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BG120460.1, DB455461.1, BC014089.2 and CA413438.1.
            
            On Nov 22, 2018 this sequence version replaced NM_138439.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript. All three variants encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU902079.1, SRR1803612.317283.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000396958.8/ ENSP00000380159.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                BG120460.1         21-30
            11-102              DB455461.1         11-102
            103-907             BC014089.2         1-805
            908-990             CA413438.1         35-117              c
FEATURES             Location/Qualifiers
     source          1..990
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.3"
     gene            1..990
                     /gene="FLYWCH2"
                     /note="FLYWCH family member 2"
                     /db_xref="GeneID:114984"
                     /db_xref="HGNC:HGNC:25178"
     exon            1..152
                     /gene="FLYWCH2"
                     /inference="alignment:Splign:2.1.0"
     exon            153..253
                     /gene="FLYWCH2"
                     /inference="alignment:Splign:2.1.0"
     exon            254..673
                     /gene="FLYWCH2"
                     /inference="alignment:Splign:2.1.0"
     CDS             352..774
                     /gene="FLYWCH2"
                     /codon_start=1
                     /product="FLYWCH family member 2"
                     /protein_id="NP_612448.1"
                     /db_xref="CCDS:CCDS10482.1"
                     /db_xref="GeneID:114984"
                     /db_xref="HGNC:HGNC:25178"
                     /translation="MPLPEPSEQEGESVKASQEPSPKPGTEVIPAAPRKPRKFSKLVL
                     LTASKDSTKVAGAKRKGVHCVMSLGVPGPATLAKALLQTHPEAQRAIEAAPQEPEQKR
                     SRQDPGTDRTEDSGLAAGPPEAAGENFAPCSVAPGKSL"
     exon            674..990
                     /gene="FLYWCH2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      960..965
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FLYWCH2"
                     /note="hexamer: AATAAA"
     polyA_site      987
                     /gene="FLYWCH2"
                     /note="major polyA site"
ORIGIN      
        1 agaagacagg gcacccgcgg ccttgctgcg catgctcgcg ctgtgacccc ggcttgaggt
       61 aacagcgcga gctgaggctg gggcccttgg cgcggaggct gagggacccg ccgcggcgct
      121 gtcgccggag agggagggca ccgctgtcgt cggccagaag ccaaggagtc ctcagtgacg
      181 gtgggatcca caacatctcc acatcgctgt ccccacccag ccagggcagc gccagcacta
      241 gctcagacgc aaggacggaa ccgctggact ccaggttcct tgcctgggag taggagaaat
      301 ccacctgctg ggggctgagt gtggcctgag ggacaggccc tgggtcccgg gatgcccctg
      361 cccgagccca gcgagcagga gggtgagagt gtgaaggcca gccaggagcc atcccccaag
      421 ccaggcacag aagtcatccc ggcagccccc aggaagccca gaaagttctc caaactggtc
      481 ctgctcacag cctccaaaga cagcaccaag gtggcggggg ccaagcgcaa gggtgtgcac
      541 tgtgtcatgt ccctgggggt gcccggcccc gccacccttg ccaaggccct cctccagacc
      601 caccccgagg cccagcgggc cattgaggca gcccctcagg agcctgagca gaaacggagc
      661 aggcaggacc caggcacaga cagaacagaa gacagtggat tagcagcggg gcctcctgag
      721 gctgctgggg agaactttgc cccctgctct gtggcgcccg gcaagtccct gtaaccttga
      781 caacaggcgc atcctcccag gccaccaacc cagccatagg ctcttctctg tccgcagggc
      841 ttctggggcc aaatgggtga atctttgctt ttaacattgt gtgatttctt ttcttttttt
      901 tttttttttt agatcaagta taagttactt ttgtaagcag aaaaatactt tcaaacaaga
      961 ataaaagaag ctgttcgcta gaccccataa
//
