LOCUS       NM_203402               1808 bp    mRNA    linear   PRI 11-JUN-2024
DEFINITION  Homo sapiens fat storage inducing transmembrane protein 1 (FITM1),
            mRNA.
ACCESSION   NM_203402 XM_090783
VERSION     NM_203402.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1808)
  AUTHORS   Kadereit,B., Kumar,P., Wang,W.J., Miranda,D., Snapp,E.L.,
            Severina,N., Torregroza,I., Evans,T. and Silver,D.L.
  TITLE     Evolutionarily conserved gene family important for fat storage
  JOURNAL   Proc Natl Acad Sci U S A 105 (1), 94-99 (2008)
   PUBMED   18160536
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL136295.3.
            
            On Aug 6, 2020 this sequence version replaced NM_203402.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038191.791864.1,
                                           SRR14038194.1305970.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000267426.6/
                                                ENSP00000267426.5
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1171              AL136295.3         78203-79373         c
            1172-1808           AL136295.3         77185-77821         c
FEATURES             Location/Qualifiers
     source          1..1808
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q12"
     gene            1..1808
                     /gene="FITM1"
                     /gene_synonym="FIT1"
                     /note="fat storage inducing transmembrane protein 1"
                     /db_xref="GeneID:161247"
                     /db_xref="HGNC:HGNC:33714"
                     /db_xref="MIM:612028"
     exon            1..1171
                     /gene="FITM1"
                     /gene_synonym="FIT1"
                     /inference="alignment:Splign:2.1.0"
     CDS             906..1784
                     /gene="FITM1"
                     /gene_synonym="FIT1"
                     /note="fat-inducing transcript 1; fat-inducing protein 1"
                     /codon_start=1
                     /product="fat storage-inducing transmembrane protein 1"
                     /protein_id="NP_981947.1"
                     /db_xref="CCDS:CCDS9611.1"
                     /db_xref="GeneID:161247"
                     /db_xref="HGNC:HGNC:33714"
                     /db_xref="MIM:612028"
                     /translation="MERGPVVGAGLGAGARIQALLGCLLKVLLWVASALLYFGSEQAA
                     RLLGSPCLRRLYHAWLAAVVIFGPLLQFHVNPRTIFASHGNFFNIKFVNSAWGWTCTF
                     LGGFVLLVVFLATRRVAVTARHLSRLVVGAAVWRGAGRAFLLIEDLTGSCFEPLPQGL
                     LLHELPDRRSCLAAGHQWRGYTVSSHTFLLTFCCLLMAEEAAVFAKYLAHGLPAGAPL
                     RLVFLLNVLLLGLWNFLLLCTVIYFHQYTHKVVGAAVGTFAWYLTYGSWYHQPWSPGS
                     PGHGLFPRPHSSRKHN"
     exon            1172..1808
                     /gene="FITM1"
                     /gene_synonym="FIT1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1789..1794
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FITM1"
                     /gene_synonym="FIT1"
                     /note="hexamer: AATAAA"
     polyA_site      1808
                     /gene="FITM1"
                     /gene_synonym="FIT1"
                     /note="major polyA site"
ORIGIN      
        1 gctgactgcc ctgctgtcgc cgcctcagca gtcagactgg gagggcaggc ttatatggag
       61 agccctgagg cccagggtag ttggttggag gatggaactt aaggtttcaa ttgactcctg
      121 tctggcaatt gcccttttag ggtctcctct acctctgtca cctgggagta aacctaatct
      181 ttagggatct gagggtcaac gtgatcaaca gatgaaaccg ccagtttata cagcagccct
      241 gggccaaact agtcccttag agaccctcaa tccagacagg aactagggca gagccaagct
      301 gctggggtca cagggcactg aagtggatac ccatgctgat ctgcctccca aggcctatga
      361 tggccacagt gctgtgcaca gccaccttgc tgcatcctgc tgttggtggg ctcttgtgct
      421 cagaacccca ggagaagggc tagatcacac tgataagact ggcagctttt tttaaaaaac
      481 gactttcaag gtttggttat ttttatctcc atgacctctg atttccctgt ggagcaaatg
      541 gtaaagtagg ggtgggtgga gagggacttt ggcagactat ggacaaggac agccctgaac
      601 agctggccct gtcacaggaa ctggaacatg gtcggagcca aggacacagg actaacagga
      661 aaggacacag actgctgtca ggacacatac taccacacac ccgaggccag gaccctgctg
      721 acgtggcaga cctccaccct ggccccttac tgccccccgc ccctctcccc cacctgccag
      781 ctgccaacag ggctctgcct tgtgtctgcc acacctgtca ctgcctatcc ttgtccaggg
      841 ggggccccat cagcccctcc tcagctgccc agcaaagcaa gcagttagtg gggaggggag
      901 ggaacatgga gcgggggccg gtggtggggg caggactggg ggccggggcc cgaatccagg
      961 cactgctggg ctgcctgctc aaggtgctgc tctgggtggc ctctgccttg ctgtactttg
     1021 gaagcgaaca ggccgcccgc cttctgggca gcccctgctt acggcgcctc taccatgcct
     1081 ggctggcagc agtggtcatc tttgggccgc ttctgcagtt ccatgtcaac cctcggacta
     1141 tcttcgccag ccacggcaac ttcttcaaca taaaatttgt gaattcagcc tggggctgga
     1201 catgcacttt cttagggggc tttgtgttgc tggtggtgtt cctggctaca cggcgcgtgg
     1261 cagtaactgc cagacacctg agccgactgg tagtaggggc agccgtgtgg cggggagccg
     1321 gccgggcctt cctgctcatc gaggacctga ctggctcctg cttcgagcca ctgccccagg
     1381 gtctgctgct ccacgagctg cctgaccgcc gcagctgcct ggcagccggc caccagtggc
     1441 gaggctacac cgtctcctcc cacaccttcc tgctcacctt ttgctgcctg ctcatggcag
     1501 aggaagcagc tgtgttcgcc aagtacctgg cccatgggct tcctgccggc gccccactgc
     1561 gccttgtctt cctgctgaac gtgctgctgc tgggcctctg gaacttcttg ctgctctgta
     1621 ccgtcatcta tttccaccag tacactcaca aggtggtggg cgccgcagtg ggcacctttg
     1681 cctggtacct cacctatggc agctggtatc atcagccctg gtctccaggg agcccaggcc
     1741 atgggctctt cccccgtccc cactccagcc gcaagcataa ctgaaagaaa taaaaaccat
     1801 cgggcctg
//
