LOCUS       NM_001109977           11517 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens FHF complex subunit HOOK interacting protein 1A
            (FHIP1A), transcript variant 1, mRNA.
ACCESSION   NM_001109977 XM_001128362 XR_015672
VERSION     NM_001109977.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 11517)
  AUTHORS   Benz,C., Ali,M., Krystkowiak,I., Simonetti,L., Sayadi,A.,
            Mihalic,F., Kliche,J., Andersson,E., Jemth,P., Davey,N.E. and
            Ivarsson,Y.
  TITLE     Proteome-scale mapping of binding sites in the unstructured regions
            of the human proteome
  JOURNAL   Mol Syst Biol 18 (1), e10584 (2022)
   PUBMED   35044719
REFERENCE   2  (bases 1 to 11517)
  AUTHORS   Christensen,J.R., Kendrick,A.A., Truong,J.B., Aguilar-Maldonado,A.,
            Adani,V., Dzieciatkowska,M. and Reck-Peterson,S.L.
  TITLE     Cytoplasmic dynein-1 cargo diversity is mediated by the
            combinatorial assembly of FTS-Hook-FHIP complexes
  JOURNAL   Elife 10, e74538 (2021)
   PUBMED   34882091
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 11517)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (bases 1 to 11517)
  AUTHORS   Mattera,R., Williamson,C.D., Ren,X. and Bonifacino,J.S.
  TITLE     The FTS-Hook-FHIP (FHF) complex interacts with AP-4 to mediate
            perinuclear distribution of AP-4 and its cargo ATG9A
  JOURNAL   Mol Biol Cell 31 (9), 963-979 (2020)
   PUBMED   32073997
REFERENCE   5  (bases 1 to 11517)
  AUTHORS   Chan,J.Y., Ng,A.Y.J., Cheng,C.L., Nairismagi,M.L., Venkatesh,B.,
            Cheah,D.M.Z., Li,S.T., Chan,S.H., Ngeow,J., Laurensia,Y., Lim,J.Q.,
            Pang,J.W.L., Nagarajan,S., Song,T., Chia,B., Tan,J., Huang,D.,
            Goh,Y.T., Poon,E., Somasundaram,N., Tao,M., Quek,R.H.H., Farid,M.,
            Khor,C.C., Bei,J.X., Tan,S.Y., Lim,S.T., Ong,C.K. and Tang,T.
  TITLE     Whole exome sequencing identifies recessive germline mutations in
            FAM160A1 in familial NK/T cell lymphoma
  JOURNAL   Blood Cancer J 8 (11), 111 (2018)
   PUBMED   30420729
  REMARK    GeneRIF: this report implicates a novel recessive germline mutation
            in FAM160A1 with familial NKTL.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 11517)
  AUTHORS   Yamada,Y., Kato,K., Oguri,M., Horibe,H., Fujimaki,T., Yasukochi,Y.,
            Takeuchi,I. and Sakuma,J.
  TITLE     Identification of nine genes as novel susceptibility loci for
            early-onset ischemic stroke, intracerebral hemorrhage, or
            subarachnoid hemorrhage
  JOURNAL   Biomed Rep 9 (1), 8-20 (2018)
   PUBMED   29930801
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC079795.6, AC097455.3 and AC092611.3.
            
            On Nov 22, 2018 this sequence version replaced NM_001109977.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 both encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803617.69112.1,
                                           DRR138518.119211.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000435205.6/ ENSP00000413196.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-290               AC079795.6         37225-37514
            291-398             AC079795.6         82750-82857
            399-523             AC097455.3         2388-2512
            524-750             AC097455.3         86002-86228
            751-1377            AC097455.3         97314-97940
            1378-1536           AC097455.3         106505-106663
            1537-1623           AC097455.3         108704-108790
            1624-1791           AC092611.3         3462-3629
            1792-1871           AC092611.3         12437-12516
            1872-2062           AC092611.3         20318-20508
            2063-3196           AC092611.3         23219-24352
            3197-3375           AC092611.3         29992-30170
            3376-3514           AC092611.3         30520-30658
            3515-11517          AC092611.3         36261-44263
FEATURES             Location/Qualifiers
     source          1..11517
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4q31.3"
     gene            1..11517
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /note="FHF complex subunit HOOK interacting protein 1A"
                     /db_xref="GeneID:729830"
                     /db_xref="HGNC:HGNC:34237"
     exon            1..290
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            291..398
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            399..523
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            524..750
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /inference="alignment:Splign:2.1.0"
     CDS             646..3768
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /note="protein FAM160A1; family with sequence similarity
                     160 member A1; FTS and Hook-interacting protein like"
                     /codon_start=1
                     /product="FHF complex subunit HOOK-interacting protein 1A"
                     /protein_id="NP_001103447.1"
                     /db_xref="CCDS:CCDS47146.1"
                     /db_xref="GeneID:729830"
                     /db_xref="HGNC:HGNC:34237"
                     /translation="MMSSVSTESKLQQAVSLQGVDPETCMIVFKNHWAQVVKILEKHD
                     PLKNTQAKYGSIPPDEASAVQNYVEHMLFLLIEEQAKDAAMGPILEFVVSENIMEKLF
                     LWSLRREFTDETKIEQLKMYEMLVTQSHQPLLHHKPILKPLMMLLSSCSGTTTPTVEE
                     KLVVLLNQLCSILAKDPSILELFFHTSEDQGAANFLIFSLLIPFIHREGSVGQQARDA
                     LLFIMSLSAENTMVAHHIVENTYFCPVLATGLSGLYSSLPTKLEEKGEEWHCLLKDDW
                     LLLPSLVQFMNSLEFCNAVIQVAHPLIRNQLVNYIYNGFLVPVLAPALHKVTVEEVMT
                     TTAYLDLFLRSISEPALLEIFLRFILLHQHENVHILDTLTSRINTPFRLCVVSLALFR
                     TLIGLHCEDVMLQLVLRYLIPCNHMMLSQRWAVKERDCYSVSAAKLLALTPVCCSSGI
                     TLTLGNQERDYILWSKCMHDTSGPVERPFPEAFSESACIVEYGKALDISYLQYLWEAH
                     TNILRCMRDCRVWSALYDGDSPDPEMFLQSLTEEGSVSSACPVFGLPQQLPRKTGPQL
                     APRKDKSQTELEWDDSYDTGISSGADVGSPGPYDDLEVSGPPAPIDPPKHIQEMKKNA
                     LLLFKGSYIEESDFQDDVMVYRLCAEKDSEDMKDSQEEAARPPAEAQAEVQSVPINNG
                     PLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPESNSELASPAPEAEHSSN
                     LTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEK
                     EGKKELEDEEDDFDSFIAEMPAVETVPSPFVGRDEAAFASRHPVRTQSTPFTGPFISV
                     VLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLAS
                     VKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMTPAALTKDPIQEASRTGSGKNLL
                     DGPPRVLQPFLTHRTKVAEAPPNLPLPVRNPMLAAALFPEFLKELAALAQEHSILCYK
                     ILGDFEDSCC"
     exon            751..1377
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            1378..1536
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            1537..1623
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            1624..1791
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            1792..1871
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            1872..2062
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            2063..3196
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            3197..3375
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            3376..3514
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            3515..11517
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /inference="alignment:Splign:2.1.0"
     regulatory      11496..11501
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /note="hexamer: ATTAAA"
     polyA_site      11517
                     /gene="FHIP1A"
                     /gene_synonym="FAM160A1; FHIP-L"
                     /note="major polyA site"
ORIGIN      
        1 agtgacccac gcgcctcagc ccgcggctga cgcaccttcg aaaagttgcg ctccgacctt
       61 ctcacgacct acattcttcc cgggcactcc tgagtttgag ccgggcctgg aggacctggg
      121 ccaagacttt cgagcggcgg ccgcccgagg tgcgaggagc cagcccggct ttcctcactg
      181 ggtcccgcgc aggcgtcccc gggaccgcag agcaaacttt ctggactatc tgaggacact
      241 tgtccagcga gccccactgc tcggggagga ggagccacgg ccggggacag gtgatacact
      301 tgggtgttga aggacatttt tgaaatcatg agaactcaat gtttgactat gaatgtttcg
      361 ttataactgc ctggaaggtt agcgtcaaag aagttgagat ttttaaagtc ttcttctagg
      421 ggtttccagc agagccaaat gttagaaaaa tctttccgct cctctgaaga gtgaagtgag
      481 caaatacaac ccagcagtag gttattgaag acagcagccc caggttttgg aaggtgacaa
      541 tgaaatgtga agaagttaca tttctcaaac ttgaaagtta gtgacggctt accaaatttt
      601 aatgaaaatt aaatatgact tagaagcatt gatttatgaa ggcttatgat gtcatcggtt
      661 tcgacagaaa gcaaactcca gcaggctgtg agcctacagg gagttgaccc agaaacatgc
      721 atgattgtat ttaaaaacca ctgggcacag gttgtgaaaa tcttggagaa gcacgacccc
      781 ttgaagaaca cccaggcaaa atatgggtct atccctccag atgaggccag tgccgtgcag
      841 aattacgtag aacacatgct cttcttgttg attgaagagc aagccaaaga tgctgcaatg
      901 gggccgattc tggaatttgt ggtctctgag aacatcatgg agaaactttt cctttggagc
      961 ttgagaaggg agtttactga tgagactaaa attgagcagc taaagatgta tgagatgttg
     1021 gtcacccagt cgcaccagcc tctgctgcac cacaaaccca ttctgaagcc tctgatgatg
     1081 ttgctgagct cttgttcagg aacaaccacc cccactgtgg aggagaagct ggttgtccta
     1141 ctcaatcagc tctgttccat tcttgccaaa gatccatcca ttttagaact cttcttccac
     1201 actagtgaag accaaggcgc tgccaacttc ctcatcttct cccttctgat tcccttcatt
     1261 caccgagagg ggtcagtagg ccagcaagct cgggatgcat tgctcttcat catgtctctt
     1321 tctgctgaga acaccatggt ggcccatcac atcgtggaga acacctactt ttgtccagta
     1381 cttgcaactg ggctcagtgg tctctactct tccctgccta caaagctaga agagaaaggc
     1441 gaggaatggc actgccttct gaaagatgac tggcttctac ttccttctct tgtccagttc
     1501 atgaactccc tggagttttg caatgcagtc atacaggtgg ctcacccctt gattcgaaat
     1561 cagcttgtca attacattta caatggattt ttggtaccag tcttggctcc tgctctccat
     1621 aaggtgactg tggaagaggt catgaccaca actgcatatc tggacctttt cctgcgtagc
     1681 atctccgagc cagcactact tgagatcttc ctccgtttta tcctattgca ccagcacgag
     1741 aatgtccaca tcctagacac tctcacgagt cgaatcaaca ccccgtttcg gctttgtgtg
     1801 gtgtctctgg cattattcag aactctcatt ggtttacatt gtgaagatgt gatgttacag
     1861 ctagttctaa ggtatctgat cccctgcaat cacatgatgc tgagtcagag gtgggctgtg
     1921 aaggagagag actgttactc tgtttctgcg gccaagcttc tcgccttgac tcctgtctgc
     1981 tgctccagcg ggatcactct gacgctgggg aaccaagaga gggattatat tctctggtca
     2041 aagtgtatgc atgacacttc agggcctgtg gagcggccat tccccgaagc gttctccgag
     2101 tcagcctgca ttgtggagta tgggaaagcc ctggacatca gctacctgca gtacctgtgg
     2161 gaggcccaca ccaacatcct ccgctgcatg agggactgcc gtgtctggtc cgccctgtat
     2221 gatggcgact cccccgaccc tgagatgttt ctccagagtc tgacggagga gggcagtgtg
     2281 agctcggcct gccctgtgtt cgggctcccg caacaactcc ccaggaagac aggacctcag
     2341 ctggctccca gaaaggacaa gagccagaca gagctggaat gggatgacag ctatgacact
     2401 ggaatctcct caggggctga cgtgggctcc ccagggcctt atgatgatct ggaggtttca
     2461 ggccccccag cacccattga tccccccaaa cacatccagg agatgaagaa gaatgccctc
     2521 ctgctcttca aagggtccta catagaagag tcggactttc aggatgatgt gatggtgtac
     2581 aggctgtgtg ctgagaagga ctccgaggac atgaaggatt ctcaggagga agctgctagg
     2641 ccaccagctg aagcccaggc tgaagttcag agtgtcccca tcaacaacgg ccccctcctc
     2701 agcacccagc cagagacaga ttcagaggag gagtggaata gggacaattc agacccgttt
     2761 cacagtgagc ccaaggagcc aaagcaagag agggaacctg aagcagcccc agaatccaac
     2821 tcagagttag catcccctgc ccctgaggca gagcacagct ctaacctgac agccgcccac
     2881 ccggagagcg aggagctcat tgcccagtat gaccaaatca ttaaagagct ggattccggc
     2941 gccgagggct tgatggaaca gaattacccc acacctgatc ccttgcttct cactaaggag
     3001 gaagaaggga aggaagagag taaaggagaa aaggagaagg aggggaagaa ggagctagaa
     3061 gatgaggagg atgactttga ctcttttata gcggagatgc ctgctgtaga gactgtgcct
     3121 tccccatttg tggggagaga tgaggctgcc tttgccagtc gccatcccgt gaggactcaa
     3181 agcaccccat tcacaggccc attcatcagc gtagtcctgt caaagctgga gaacatgctg
     3241 gagaactctt tacatgttaa tttgctgctt atcgggatca ttactcagct agccagctac
     3301 ccccagccac tcctgcgctc ctttctgctc aacaccaaca tggtcttcca gccaagcgtc
     3361 cgctctctct atcaggtcct tgcatctgtg aaaaacaaga ttgaacagtt tgcttctgtg
     3421 gagagagact tcccagggct cctcattcaa gctcagcagt acctgctctt ccgtgtggac
     3481 atgtctgata tgacccctgc agcactaacc aaagatccca ttcaggaggc ttccaggaca
     3541 ggaagtggca agaacctttt ggatggacct ccaagagtgc ttcagccctt cctgacccac
     3601 agaaccaagg tggctgaggc accccccaac ctgcccctgc cggtgaggaa ccccatgctg
     3661 gctgctgccc tcttcccaga gttcctgaag gagctggcgg ccttggccca ggaacactcc
     3721 attctgtgct acaagatctt gggtgacttt gaggactcct gctgttagct tttttttttt
     3781 tttttaatag aggttcttgt tttgtaaggt tttagtgtct tgactgaatg ttaaatgcaa
     3841 agctgcttac aaagatttct actttaatgt ttcctgacaa tacttgattt gtggggaggg
     3901 gaattttctg tatctttcct ctctctctct agccgggcct ttccacctta tgttatatat
     3961 agaatgtaag tctcataagc tggttgctcc cttggcagtt ttctttgctc tgtttttcct
     4021 ccttatattt ttttggttgt cattctccta tccctttgag ttactcttct tgcagctcag
     4081 atcacgtcaa gcagatattg gggttcagtg atgtctggtg atgtctggaa gtgccccatg
     4141 tcagaattcc agctgttcag cagcacagga agattgtaca cctgcaactg tgcgaatggt
     4201 cctgttgcct cctgcatttt ggcctctgtt ctataaagga agagtaaaga tggagctcct
     4261 cctgcctcca tcacgaaagc acatatcatc tgtccctttg gattttactt ccaggacgtg
     4321 tgtcgtcccc agcgtgtgtt gccttatggt gccggcagag cctcagctat ctgcctggga
     4381 agtcggatgt ccttggagag aatttggaat gcagataatt tttcttattt cttgagagct
     4441 tactttaatc agcatgacac tacctaaaca ctgaagatgg ccttatatta gtaagatttg
     4501 cacaaaatta agtataccta tgcaaactat tactttggtt tttaggagtt tgatcagatg
     4561 aagaagtaat ggtatcacat atatatgtaa gaagacaacc atcattattt ttgtaagtgt
     4621 tttataaaaa caaactgatt aacttgtgaa gccatttcat agtgggtttt ttcagggagg
     4681 gtatgctggg tgggatgggg agataaacta aatgcagcct gtaaaaacac tgatcattat
     4741 ttaaaattct attccctttt gctagtaagc tgcactttgt agagaaacag gaactgtaca
     4801 gcccactttg ggaccttgga tgtaaatgca aacaggtcac ctggagccct gcaaagccaa
     4861 gtgcctgctg gcgactcact ctgcatggaa atgctgcctt ccgagtaatg gggttcatta
     4921 gaaggcccca acgtgctgta tgagcgtccc tctgctgctt tgcagcctgc tccaagaggc
     4981 aggattatac ttagagccac agccatgtta aaccaccacc aagaggggaa aacagaataa
     5041 ttgtgagctg aaaatgagac cataaacaac tgatttttat ggatattaaa ttccactccc
     5101 ctctattttg ggcccagttc tgcaggtgcg aagcaagtaa cgagcttgag cctgcctgtt
     5161 tggaaggaaa ttggaaggtt tgtctctctc tgttctttgt gggcatctct gtggagccct
     5221 gagggcagcc acaggtctgg tggttgtgcc tcaggagcac tggtttggtc ttaatcaggc
     5281 ctttcatgca caggcagggc agtggcggaa gaaccacacc tgcaatgctg tggagcagtg
     5341 gaggcccttt tgtgcttcag gaatcttgaa gcagctttgt attgagtgaa tgagaaattg
     5401 agagctggcc tgtgaaatga caacaggaga cctggcctgg gcagggtgag ctgttaggag
     5461 ccagccttgc tttcgtgttt catagtccaa gcaagacacc aaagattcct actcactgta
     5521 catttctgtt tgtcttgaca aatggtttgc tcagctgtgg tgcagcagcc agaagggatg
     5581 aagcacagca gactggtctg cttctggctt cctgatgtct ggttgtattt gcacagccca
     5641 caactctcca ttagaaaaga aggtagctta agatagagaa agaggaacag ttgaagatgg
     5701 aagttcggct gtaatttatt atactctgtt tgtttttgca caagtattta tcttcttgtt
     5761 tggacttaca aagtcataaa atgccaacgc cacatctgta aatggaattc tttagctttg
     5821 tagtttgatt tacacctttc tccattatct ggtggtggtg ttgattcttc ttgaatccat
     5881 atttctgcat tgtagaatac catggtcccc tttgtggaaa gtttcctttg ggaaaagatt
     5941 gattttgtgc ctcttactgt ttttttcaat aggtactgaa ataaacttac tttattattt
     6001 tatttttttg agacaggatc ttgcgctgcc tgggctagag tggagtggtg tgatcacagc
     6061 tcattgtagc ctcaacctcc tgggctcaag tgatcctccc acctcagcct tccgagtagc
     6121 tgggaatata ggaacgtgcc accacaccca gctaactttt tggtatagtt tgtagagatg
     6181 gggtttcacc ttgttgccca ggctggtctt aaagtcctgg gctcaagtga tcgtcccgcc
     6241 ttggcctccc gaagtgctgg gattacaggt gtgagccact gggtccagcc tgaagtagac
     6301 ttactttaaa tgaggacaga gatgactggt gtgtgcagtg acaggcagga gaatgtaact
     6361 tcccatgctg gggtgctggc agcaaactca cacgataaca ctaacttcct atttggattt
     6421 ggaaactggt tcctgtttct gaatccatta cagtcctcag aggtttttgt ccatggtttt
     6481 gcaaaatgaa gtcagaaaat ggagctggat gtagagagaa caggaaaacc catgtggctg
     6541 ggtgaaataa ctgagagtgg gttatttagg gagtgacgtg gacatgccaa agaaaaacag
     6601 cagagaactg agtctatcca cgggagaaga gcaaatcctg cacgattcgg gggagtgaac
     6661 attgatctag gcggatatga agaaaccagg gagtgggtgg gtgagaatgg gaactccttg
     6721 tcaggaaaaa aatcattggc aatgaagtag aatattctgg tcctaaagta aatcggcaag
     6781 cccttagaaa tatctttttt tataatgagt tggggggaaa atcttaaata tgtttggcat
     6841 gcttaaagat atggtccgag agtgtggaca cttctctatg tgacaggctc ctacaccagt
     6901 cgctgtgctc cttgctggaa gaatgtaggg gaagagaaac cgtgggtacc gcccgctggc
     6961 gcagcccctg agctggcgtc actgcgtctg gcctgggcag gaaaggtgag ggagccaagg
     7021 gttcctggag tatcacaaca ttaacctcaa ttcataattc agggcccgac ttaaagttcc
     7081 agactgagtg acttctgtgg ttcaaaatat atgagagcac tgggatattt aaaattgatt
     7141 ttttggaaat ggccaagtaa atgtttttta aaattttaca caaagaaatt ccaacttagg
     7201 ttcagcctaa aacataattt catgggtggt aaaatacaat ttcccaacca tgaaatggga
     7261 gtgctggaat agccagttag agatgtgatt tttctttacc attagatacc tcctttccct
     7321 ggtatttaga ggaattgtga agtggtcccc attttgtgga gtatcatttt ggaaaatgct
     7381 ttgatgtgct cgggttggag tggatgtctg tcaggtgtta ggtaggacgc attcggtatt
     7441 tttataggtc atcaggagta ccctttcctt agcaggtgga ttttatttag gtcagatata
     7501 gttagtttct gtccaggata agacatcatg gagccagggt cttgtcagga aagcatcctc
     7561 ttatgaacag aatctagaaa caggctacat gaatattggg gttgcctgtt taatttgggc
     7621 agccagtggg tactcagggt cgaaagttgt ttccagtgtc tccaaatcag cttggctgtg
     7681 gccgtcatgt ggactgattc ccaggtctgt ttgaggttta gggttgtgga tgggctgctc
     7741 ttctgaatct ggatcagtgt gtctaggttg tgttcaggag ggaagcacag ccgcagcagt
     7801 ctggacaaat caagtgcttt aacgatggca tcgtcctctg ggaataatca gtccttaata
     7861 cagttttcac ttgacataat agttttggta aactgtcttt atctggctgc accccctttt
     7921 aagtaagccc ttaattttaa atggtcccgg cgtggtgttc agtatctgca tatgccccag
     7981 ttctcattta agggcagttc aatgtaattg ctaattacca gccctgtatt tactgaaatg
     8041 gctgtctgtc atgcttgcca tttttatgaa acactttatt gcaggtcagc tattattgca
     8101 cgtgctactt caagtcactg gctcaggctg gtgtcatgtg tggtttgctg caaacggcag
     8161 cctgctttgc agtgtgagct cttcctggaa acagcagtct cttgtagctg atgccacatc
     8221 agctttaagt cattaggaag atattctagg ccccttgttg cttcagccat cagtctataa
     8281 ataacacaac actaattttc catcaagtaa cagcttaaaa cagaacactg tcaaaccact
     8341 ttatgttcca cccttaaatc acatcactga ggaaacactg taagagaatg cagttgactc
     8401 tttccccccc ttctttttga atgaacctcg taaacctaat gctttagaaa gagctctcag
     8461 aagactgaga atggttttta ggataatttt gcctcagtaa atcctctcta cattcaggca
     8521 tttattaggc cattacttgt tttgggacta cagattatcc tggcagctca ataactggat
     8581 aaacaggact ttagtgaaag attttcagag gttctttagg gaaaagaatg accaggagaa
     8641 ggtgggtgga agccttcagt tctttgacct cttgcacgta gaatcctaaa actgatcatg
     8701 attttagcta ggactgacct ttcctagctt gtagggtcac tgtgaatttt gttcatgtct
     8761 taaaaggttt aagttaacct agttcactgt tacctacaca agtaacaaga cggccaatag
     8821 gacctgtcag catgacttcg acatgcattc caggcatctt tcggggagtt tagatttact
     8881 gtgtcatttc agaacccaac aaaggtgatg gaagctctta ggccagatta aatttcatgg
     8941 aacggaggct gcagaagtct gtgctgctta gtgtgtcagc tgacttttta ctgggacaag
     9001 tctatgaaag gcccacctgt aacaaggccc ctttttgccc tgtggatatt ttaaaagagg
     9061 gaatttggtg ttgacaatct tacttacacg actcttgcta agctatttga ctaagggttt
     9121 caatcagatg cttcccacct cacaagcaag ggtcagctct atttgcaaat aatccatgaa
     9181 tatgtttgtc taaaacctgc tgaagaggca tggcagccac ttccatgctg cttttggtaa
     9241 tgggtaaaga atatggcctt tcagatagat ctggtggctt ttccccaata gtcaccatgt
     9301 ggaaactatg caactaaatt caatggaaat gaaagataca atataaaata gcgggtcatg
     9361 gccataagct gtgtcctgaa ctaaccaact ccaagctgaa ggagggtgtg tactttccga
     9421 aacttcgagg ccatcttagt aattatttta gcaataatta ctaaaatgta catggggtgg
     9481 gggagctcag ctaaaatatc cttactttgg tgcaataatg atctaggttc tttttcctag
     9541 gcctaggcct ccaccttgaa agacaggaac agaagttcac tgtgatgtgt gaccctggac
     9601 agagatcaaa cagctccttt ctagacccag atgacccaga acgcagaagc ctagtagttg
     9661 gtatcaccag tgtctcttca aaagggcccc acaaaaggct gtccattaat ttgtttcata
     9721 cagtaagcga gcttttactg aatactccct ctgttaggta gcatgcagag tgctagggct
     9781 ggcacattcc tgccttccca ccagaaccct ccaacctcct ccccaggcaa cagaacacag
     9841 ggtttgggcc tgaccaggca gagctggttc aagccagcct ggggcagagc cagttttcca
     9901 gcacacttct aacttctagt cagagcctca gcattataca cccagcctac aggtgtgtgg
     9961 attcctgaga cagatggcaa tggcatcacc tgtggtgcca actcatacat tttaatgaga
    10021 tttctccctg aagggtgaac cagtagacca gactaaacgc acactcatgc aagaatgtaa
    10081 aattgtattt cactgaggcc cctttataag cagagccatc tttgcgaatt tcttggggtg
    10141 ttaatgtaaa catatcttta gaatatctca tcgggtttca gtcagagcca tgctttgggt
    10201 ttttcctagc agcagtgatg atatcaactt acaaggtttg gctttcagga tttcagaagc
    10261 tggcattcaa gacaacaggc agtttgtcag agctgaatga gaatcagcct ggacaaatca
    10321 agtgctttaa caagggcatc ttcctctggg aataatcagt ccttaataca gtttgcactt
    10381 gacataatag ttttggtaaa tgtctttttc tggctgcacc cccttttaag taagccttta
    10441 attttaaatg gtctggaaag atcttcgatg ctttctgtaa ggtttagtca ccaagaagcc
    10501 agaacttttg gtgaaaacag aatttataaa atgaaactga accttctcct ttcttacaaa
    10561 ataaagatcc tgtcagactc cagtctcaga ccacctttgc ccatttgtaa ttcagacttg
    10621 cagagtgagg agagaactgc ttcagcctta ctgtcttgta gagagatttg gtgaaaatca
    10681 tgttacttta gacccagtag ttttcaggac cgcaacagga tgcggggcac ctggcttccc
    10741 gggtaaggtc acatagtctc ttaaaattct gtcactaatt tttttaaacg acttttttta
    10801 aaaagccacc tcctcatgcc tgtccaaaat gaaccacgca actggttacc tttctctgcc
    10861 taccttttgg gctggggaag aggggcacct ttctcatcac tctcagggaa gtcctgagga
    10921 actgtgcaag ccaggaagca tgagtcgctg aattggtgat ggaggggtgt ccactttttt
    10981 ctagttcctc agctgcttct ggagcagtgt tcacaacggg aatgttttta ctgtccttgg
    11041 taggctacag gttcacagct tcaaatcaag gcctccaagg attttattct cttacatcac
    11101 agttttgaca agtatgcttt taaaaaacaa catttgcaaa actggtcttt aagcgacgtg
    11161 agtcagaggt aacaaaggca tatatatacc gaacaaaggt gctccggtgc agtggagaga
    11221 acagtattag tgtcgcaagc acaggagtgc agacagcccc gccttcatcg tgatgcctgc
    11281 agcacaccac gattatcatg agaggtcaag attttgattt actaatttat aatcttattt
    11341 ccaagcaaaa caagtcaatt tcatgttaca acttttttct tgtttctttt tatcttgttt
    11401 ggcctgaggg ttgggggatt tgggggagtt gtcagctgca caatctttga agtgtaagtt
    11461 aatttttatg tgatatttca gtatatattt tattgattaa atttattgga aaactta
//
