LOCUS       NM_002003               7588 bp    mRNA    linear   PRI 09-FEB-2025
DEFINITION  Homo sapiens ficolin 1 (FCN1), mRNA.
ACCESSION   NM_002003
VERSION     NM_002003.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7588)
  AUTHORS   Gao,P., Tang,K., Lu,Y., Wang,M., Wang,W., Wang,T., Sun,Y., Zhao,J.
            and Mao,Y.
  TITLE     Increased expression of ficolin-1 is associated with airway
            obstruction in asthma
  JOURNAL   BMC Pulm Med 23 (1), 470 (2023)
   PUBMED   37996869
  REMARK    GeneRIF: Increased expression of ficolin-1 is associated with
            airway obstruction in asthma.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7588)
  AUTHORS   Moulana,Z., Bagherzadeh,M., Mirzakhani,M., Rostami,A.,
            Mohammadnia-Afrouzi,M. and Shahbazi,M.
  TITLE     Increased Levels of serum Pentraxin 3 in Critical Coronavirus
            Disease-2019 Patients
  JOURNAL   Environ Sci Pollut Res Int 29 (57), 85569-85573 (2022)
   PUBMED   34212320
  REMARK    GeneRIF: Increased Levels of serum Pentraxin 3 in Critical
            Coronavirus Disease-2019 Patients.
REFERENCE   3  (bases 1 to 7588)
  AUTHORS   Brix,N., Glerup,M., Thiel,S., Mistegaard,C.E., Skals,R.G.,
            Berntson,L., Fasth,A., Nielsen,S.M., Nordal,E., Rygg,M., Hasle,H.,
            Albertsen,B.K. and Herlin,T.
  CONSRTM   Nordic Study Group of Pediatric Rheumatology (NoSPeR) group
  TITLE     M-ficolin: a valuable biomarker to identify leukaemia from juvenile
            idiopathic arthritis
  JOURNAL   Arch Dis Child 107 (4), 371-376 (2022)
   PUBMED   34686494
  REMARK    GeneRIF: M-ficolin: a valuable biomarker to identify leukaemia from
            juvenile idiopathic arthritis.
REFERENCE   4  (bases 1 to 7588)
  AUTHORS   Olszowski,T., Milona,M., Janiszewska-Olszowska,J., Safranow,K.,
            Uzar,I., Walczak,A., Sikora,M., Chlubek,D. and Adler,G.
  TITLE     FCN1 polymorphisms are not the markers of dental caries
            susceptibility in Polish children: A case-control study
  JOURNAL   Oral Dis 28 (3), 771-776 (2022)
   PUBMED   33600013
  REMARK    GeneRIF: FCN1 polymorphisms are not the markers of dental caries
            susceptibility in Polish children: A case-control study.
REFERENCE   5  (bases 1 to 7588)
  AUTHORS   Li,Y., You,E.Q., Lin,W.H., Liu,X.N., Shen,D.P., Zhang,X.L., Ma,D.C.
            and Li,H.M.
  TITLE     Association of ficolin-1 and ficolin-3 gene variation and pulmonary
            tuberculosis susceptibility in a Chinese population
  JOURNAL   J Clin Lab Anal 35 (4), e23732 (2021)
   PUBMED   33591573
  REMARK    GeneRIF: Association of ficolin-1 and ficolin-3 gene variation and
            pulmonary tuberculosis susceptibility in a Chinese population.
            Erratum:[J Clin Lab Anal. 2021 Dec;35(12):e24092. doi:
            10.1002/jcla.24092.. PMID: 34817895]
REFERENCE   6  (bases 1 to 7588)
  AUTHORS   Harumiya,S., Takeda,K., Sugiura,T., Fukumoto,Y., Tachikawa,H.,
            Miyazono,K., Fujimoto,D. and Ichijo,H.
  TITLE     Characterization of ficolins as novel elastin-binding proteins and
            molecular cloning of human ficolin-1
  JOURNAL   J Biochem 120 (4), 745-751 (1996)
   PUBMED   8947836
REFERENCE   7  (bases 1 to 7588)
  AUTHORS   Endo,Y., Sato,Y., Matsushita,M. and Fujita,T.
  TITLE     Cloning and characterization of the human lectin P35 gene and its
            related gene
  JOURNAL   Genomics 36 (3), 515-521 (1996)
   PUBMED   8884275
REFERENCE   8  (bases 1 to 7588)
  AUTHORS   Matsushita,M., Endo,Y., Taira,S., Sato,Y., Fujita,T., Ichikawa,N.,
            Nakata,M. and Mizuochi,T.
  TITLE     A novel human serum lectin with collagen- and fibrinogen-like
            domains that functions as an opsonin
  JOURNAL   J Biol Chem 271 (5), 2448-2454 (1996)
   PUBMED   8576206
REFERENCE   9  (bases 1 to 7588)
  AUTHORS   Lu,J., Tay,P.N., Kon,O.L. and Reid,K.B.
  TITLE     Human ficolin: cDNA cloning, demonstration of peripheral blood
            leucocytes as the major site of synthesis and assignment of the
            gene to chromosome 9
  JOURNAL   Biochem J 313 (Pt 2) (Pt 2), 473-478 (1996)
   PUBMED   8573080
REFERENCE   10 (bases 1 to 7588)
  AUTHORS   Ichijo,H., Hellman,U., Wernstedt,C., Gonez,L.J., Claesson-Welsh,L.,
            Heldin,C.H. and Miyazono,K.
  TITLE     Molecular cloning and characterization of ficolin, a multimeric
            protein with fibrinogen- and collagen-like domains
  JOURNAL   J Biol Chem 268 (19), 14505-14513 (1993)
   PUBMED   7686157
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA813504.1, AK314867.1,
            BC020635.1, AL353611.19, AL603650.10 and AL833097.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_002003.4.
            
            Summary:  The ficolin family of proteins are characterized by the
            presence of a leader peptide, a short N-terminal segment, followed
            by a collagen-like region, and a C-terminal fibrinogen-like domain.
            The collagen-like and the fibrinogen-like domains are also found
            separately in other proteins such as complement protein C1q, C-type
            lectins known as collectins, and tenascins.  However, all these
            proteins recognize different targets, and are functionally
            distinct.  Ficolin 1 encoded by FCN1 is predominantly expressed in
            the peripheral blood leukocytes, and has been postulated to
            function as a plasma protein with elastin-binding activity.
            [provided by RefSeq, Jul 2008].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC020635.1, SRR5189655.132754.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2142670, SAMEA2149004
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000371806.4/ ENSP00000360871.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 DA813504.1         92-94
            4-1022              AK314867.1         1-1019
            1023-1235           BC020635.1         1002-1214
            1236-4362           AL353611.19        2001-5127           c
            4363-6790           AL603650.10        129039-131466       c
            6791-7584           AL833097.1         1351-2144
            7585-7588           AL603650.10        128241-128244       c
FEATURES             Location/Qualifiers
     source          1..7588
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q34.3"
     gene            1..7588
                     /gene="FCN1"
                     /gene_synonym="FCNM"
                     /note="ficolin 1"
                     /db_xref="GeneID:2219"
                     /db_xref="HGNC:HGNC:3623"
                     /db_xref="MIM:601252"
     exon            1..144
                     /gene="FCN1"
                     /gene_synonym="FCNM"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..1022
                     /gene="FCN1"
                     /gene_synonym="FCNM"
                     /note="ficolin (collagen/fibrinogen domain-containing) 1;
                     M-ficolin; ficolin-A; ficolin-alpha"
                     /codon_start=1
                     /product="ficolin-1 precursor"
                     /protein_id="NP_001994.2"
                     /db_xref="CCDS:CCDS6985.1"
                     /db_xref="GeneID:2219"
                     /db_xref="HGNC:HGNC:3623"
                     /db_xref="MIM:601252"
                     /translation="MELSGATMARGLAVLLVLFLHIKNLPAQAADTCPEVKVVGLEGS
                     DKLTILRGCPGLPGAPGPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEK
                     GDAGQSQSCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQR
                     RMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFA
                     KYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQG
                     AWWYADCHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA"
     exon            145..258
                     /gene="FCN1"
                     /gene_synonym="FCNM"
                     /inference="alignment:Splign:2.1.0"
     exon            259..312
                     /gene="FCN1"
                     /gene_synonym="FCNM"
                     /inference="alignment:Splign:2.1.0"
     exon            313..348
                     /gene="FCN1"
                     /gene_synonym="FCNM"
                     /inference="alignment:Splign:2.1.0"
     exon            349..381
                     /gene="FCN1"
                     /gene_synonym="FCNM"
                     /inference="alignment:Splign:2.1.0"
     exon            382..509
                     /gene="FCN1"
                     /gene_synonym="FCNM"
                     /inference="alignment:Splign:2.1.0"
     exon            510..639
                     /gene="FCN1"
                     /gene_synonym="FCNM"
                     /inference="alignment:Splign:2.1.0"
     exon            640..774
                     /gene="FCN1"
                     /gene_synonym="FCNM"
                     /inference="alignment:Splign:2.1.0"
     exon            775..7588
                     /gene="FCN1"
                     /gene_synonym="FCNM"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1234
                     /gene="FCN1"
                     /gene_synonym="FCNM"
                     /note="major polyA site"
     regulatory      3135..3140
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FCN1"
                     /gene_synonym="FCNM"
                     /note="hexamer: GATAAA"
     polyA_site      3157
                     /gene="FCN1"
                     /gene_synonym="FCNM"
     regulatory      3348..3353
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FCN1"
                     /gene_synonym="FCNM"
                     /note="hexamer: AATAAT"
     polyA_site      3377
                     /gene="FCN1"
                     /gene_synonym="FCNM"
     regulatory      7560..7565
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FCN1"
                     /gene_synonym="FCNM"
                     /note="hexamer: AATAAA"
     polyA_site      7588
                     /gene="FCN1"
                     /gene_synonym="FCNM"
ORIGIN      
        1 gttagagctg ggggactctt cagagtcaaa ggccagagag catggagctg agtggagcca
       61 ccatggcccg ggggctcgct gtcctgctag tcttgttcct gcatatcaag aacctgcctg
      121 cccaggctgc ggacacatgt ccagaggtga aggtggtggg cctggagggc tctgacaagc
      181 tcaccattct ccgaggctgc ccggggctgc ccggggcccc agggccaaag ggagaggcag
      241 gtgtcattgg agagagagga gaacgcggtc tccctggagc ccctggaaag gcaggaccag
      301 tggggcccaa aggagaccga ggagagaagg ggatgcgtgg agagaaagga gacgctgggc
      361 agtctcagtc gtgtgcgaca ggcccacgca actgcaagga cctgctagac cgggggtatt
      421 tcctgagcgg ctggcacacc atctacctgc ccgactgccg gcccctgact gtgctctgtg
      481 acatggacac ggacggaggg ggctggaccg ttttccagcg gaggatggat ggctctgtgg
      541 acttctatcg ggactgggcc gcatacaagc agggcttcgg cagtcagctg ggggagttct
      601 ggctggggaa tgacaacatc cacgccctga ctgcccaggg aagcagcgag ctccgtgtag
      661 acctggtgga ctttgagggc aaccaccagt ttgctaagta caaatcattc aaggtggctg
      721 acgaggcaga gaagtacaag ctggtactgg gagcctttgt cgggggcagt gcgggtaatt
      781 ctctaacggg ccacaacaac aacttcttct ccaccaaaga ccaagacaat gatgtgagtt
      841 cttcgaattg tgctgagaag ttccaaggag cctggtggta cgccgactgt catgcttcaa
      901 acctcaatgg tctctacctc atgggacccc atgagagcta tgccaatggt atcaactgga
      961 gtgcggcgaa ggggtacaaa tatagctaca aggtgtcaga gatgaaggtg cggcccgcct
     1021 agacgggcca ggacccctcc acatgcacct gctagtgggg aggccacacc cacaagcgct
     1081 gcgtcgtgga agtcacccca tttccccagc cagacacact cccatgacgc ccacagctgc
     1141 ccctttgccc ccagctcagt caagccgcca catgcccaca acctcaccag agggagaatt
     1201 atgtttctaa atatgtttac tttgggacag aaaagtttta ccagtttcaa tgtgtgtttc
     1261 ttgaacacca gtggttttga tcactttcct gtgtctgttg cacggcaggt ctttccctgg
     1321 aatttggtaa gtcgggaaga gtcaggaccc ttatttagca gatggcacta ccgatgttca
     1381 gggaggttga gtgacttttg cgaggatttt ccacctccag taattgacac agggcgatcc
     1441 tcacctccac ccccaagcct cccccatccc cccatgcctc actcacaaca cttcacactt
     1501 cttgaaaaag gtcactttgg ggtccagaaa acacttacta aaaaggggga aagtttagta
     1561 ggaacttttc tgcttcccac cacggcagag ttcatgcttt gggctggctg gctgctggga
     1621 agagataaac acttagcact cactaagtga gcgcctggtc agccacctgc acagagaaga
     1681 ttccgaagag gccttcctcc cacacacaga cctcagctag aggggaccgc ggacctcagt
     1741 gggaaaagct gcacaaggct tctaggagat gatggagaag gggcttctcc agctcccagg
     1801 ccaggggaga tttctcaacc acgacctaag aagcatcaaa gggaatgtgg caagtgtgac
     1861 tccattcaaa tcaagagctc ccacttaccg aaggacacta agggaaccaa aggaaggcca
     1921 gaggggcaga atcaacgtgc ggcacacaaa tctttagttt tctactattg ccgcaaccag
     1981 tcaccacaaa tggagtggct tgaaacaaca agaactcgcc acctcctggc tcagtagatc
     2041 tggagtccct gggccttact gggccagcag gcaggactca gcagtggtgg ctccttccag
     2101 ggttctaggg gagaacctgc ttccttgcct tttccagccc caggggtcac tggcattcat
     2161 tggcccggac tccttccccc aaccccaaag ccagcagcac cacatctctc tgacccttca
     2221 tccgttgtcc cctctccccc caagccccat gggacagggt ctccactcct gagactcatg
     2281 ggattagact aggcctacct ggatgatctg ggatcctctc ccatgtccag gtctctatcc
     2341 ctaaccacat cagcaaagtc tcttttgcca tggaaggtat ttgcaggctc tgactttgtg
     2401 tgtattaggg caggacattt ttggcggggc agtggtgggg gcagggaatt attctgccta
     2461 ccatgcctta tacaaaaata aataaatcac aggcttatac ctgaaagaat tcctgcaaat
     2521 aataaaagaa ttagagcagc tcagttaaat aaaaaaaggt atgagatgtg aacagacact
     2581 tcacagaaga tgacatgcag gggagcaagg tatttatcaa aaagtgctcc acttttcact
     2641 taccagagaa atgcaaatca gcacccaaag gagtcactgc ggcaccctca tctgagcctc
     2701 agaagttaga aagatggata gcaccagtgt caaaggtgac tgtgggaggg agatttgcat
     2761 acactgctag taacaatgcg aattgatgga accaacctgg aaaatggctt ggcatcaact
     2821 gttggagaag aagacacaca gtcctctaac ctgccagtcc cacatcaggg cctggatatg
     2881 gccgtcatgt gtaccaggga gcatggccag gaatctttac agccaaatac tcaccatagc
     2941 accaaactgg aatcagccga catacccatc aggaagagaa tggatgttaa aaaatgcaag
     3001 gatagccatt gggtagaacg ccatacagcc atgacaatta cacagtgaca cctacacaca
     3061 aggagcatga gtctcacaaa catggcagca aaaggagcct gttcaagagg gtatgtgcta
     3121 tggattccat tgtagataaa gtttttcaaa agcaaaagta gccaatggta ttttggatgc
     3181 atatttaggt ggtaaatgta tacaggaaaa ataagaaagt gattgtattt gagggtggga
     3241 ccacatggtg actgggaagg gacagggaca agcctctggg gttctggcaa tgctctgttt
     3301 cttgacccag gtggtgattg taaggatgtt tgttaactag tgatgaaaat aattaagctg
     3361 tacttttgct ttatacactt ttgagtacat gttatgttcc acaatttaaa aactacttat
     3421 aaagaaactg cacatgcttg gatccaggaa catgagctac aggcacatcc tccactgatg
     3481 cccagtgttc ttgactcaat acctgtaagg agaggtcctt gtagcccatt gggggctgac
     3541 cagaccctac tacgcccctg ccacaatctc tagtccatca caaaatccac tattgggata
     3601 gtactttcgt ccctcagtag gtaagcattt ttacaaccta ggaagactta gctttaagtc
     3661 tagaaatgat tagtataaat ataaaatata aatatgatta atataaatat aaaatagcca
     3721 tagaaatatg ccttttagtt tgttttttga gacagagttt tactctgcca cccaggctgg
     3781 agtgcagtgg cgtgatctca gctcactgca atctccacct cccaggttca agagattctc
     3841 atgcttcagc ctcccaagta gctgggatca caggcacaca caaccatgcc cagcaatttt
     3901 tttgtatttt tagtagagat ggggtttcgc cgtgttggcc aggctggtct tgaactcccg
     3961 acctcaagtg atccacccgc ctctgcctcc caaattgctg agattacagg cgtgagacac
     4021 tgtgcctggc caaaatatgc cttttgtatt aaggaatctg gacaggtttg atttttcaca
     4081 gtcttgtaat gtttaaataa tttggcctat tatgaagaat ctcacaaatc caatataaaa
     4141 tgtggaacta actaatcaaa atcatcttgt aatattacat ggaaatctta gtgcgtttat
     4201 acacggtatt ggcatattta agagactttg agctcattgc atttctaagt taaattatta
     4261 gatttcttaa gatttaagtt aaattattag atttttaaag attaattagt gctaaggagg
     4321 gttttctcat tagacagctg aaatgccgca ggagaaattt gagtgtattc cacttcttat
     4381 tgcaatttta aatgtttgaa gttatttaaa gaactaaatt tatggtatcc aaaagctcta
     4441 aaaaggtgac tcttaagatt tgcaggtctt ataaatagaa aaacaagaac tgtaagccaa
     4501 acttaaaata ttcaggatga attgagtttt tgaatttgta gctttcagaa actgaacatt
     4561 aattttaaga agcaaagcag gctgggcaca gtggctcacg cctgtaatcc tagcacttta
     4621 ggaggctgaa gtgggtggat cacttgagat caggagttca agaccagcct ggccaacatg
     4681 atgaaacctc ctctctacta aaaatacaaa actccgccag aaatcgcttg atcccgggag
     4741 gtggaggttg cagtgagctg agatcgtgcc actgcactcc agcctgggga acagagcgag
     4801 attccgcctc aaaaaaaaaa taaaaataaa aagaagaaga agaagaagga gaaagaggga
     4861 gagggagagg gagagggaga gggagaggga gagggagaag aagaagaaga agaagaagaa
     4921 gaagaagaag aagaagaaga agaagaagaa gaagaggaag aggaagagga agaggaagag
     4981 gaagaggaag aggaagaaga agaagaagag gaagaagaag aagaagcagc agcagcggcc
     5041 aggcgcggtg gctcacgctt gtaatcccag cactttggga ggccgaggcg ggcggatcac
     5101 aaggtcagga gatcaagacc atcctggcta acatgatgaa accccgtctc tactaaaaat
     5161 acaaaaaaat tagccgttca tggtggggga tgcctatcgt cccagctact cgagaagctg
     5221 aggcaggaga atggcgtgaa cccaggaggc agaggttgaa gtgagccgag atcgcaccac
     5281 tgcactccag cctgggcgac agagcgagac tctgtctcaa aataaaagaa gcaaagcaag
     5341 cttatgaaga gatgaagagt cttttcccat caccaattcc tccccaactc acatcagcag
     5401 aactgagaga gcttttgtga tttgagggat aaagctgaat gggtgaaaag aaatcaagcc
     5461 ctcctcctct tgggccagtg ctcttcttcc tggccatggg acctctcaag taggagtgta
     5521 ggcgtgggcc catccagcaa catttgggca ttcgtggaca tccacatagt gttgtttctg
     5581 ttcttttcct ctccttcctc atcttctctc gtctttgttg aatattttta ttatcccgtc
     5641 acctcctcta tcagcttata acttgttcat tcttttccta tcttttggtg tttatgcttg
     5701 cgattgcaat atatagcctt gattttttac ggtatactat aaattattcc ttctaccact
     5761 ttaccaatga agactttgaa acacctctaa ctacattcac tcccttctgc tttttatgcc
     5821 attcttgccg ccatgctatg atacatttat ttaaagtcct gcaagaaatg gctattagta
     5881 ttgttttgtg cagtccgtat tcatttttac cacattttta cactttatgt tgccctttat
     5941 tccttcttct attttattat tattattatt tttggtgtga gatcatcttc ttgctgcctg
     6001 acaaactccc tttcatatat attttttatt tttatttttt gaaacagggt ctcactctgt
     6061 cccccaggct ggagtgcagc ggtatgacct tagctcactg caacctccac ctcctgggct
     6121 caaacaattc tcctgcctca gcttcccgtg tagctgggac tacaggtgtg caccactacg
     6181 ctgggctaat ttttgtattt tttggtagag atggggtttc gccatgttag ccaggctgct
     6241 cttgaactcc tgacctcaag tgatccaccc gcctcagcct cccaaagtgc taggattaca
     6301 gatgtgagac accgtgccca gcctcatata ttttttgatg aaagtctgct gaggatgaat
     6361 tctgtccact tttattatct gaaaacatct ttattttgcc tcattttaaa tagtatttag
     6421 attgggtgta gacttctata ttgccaatta gtttctttta gcactgtaaa tacagatgtc
     6481 cagtattttc agattcagtt atttcagctg aaaagctagc tgaaagtctt gttgctcctc
     6541 tgaaggtaat atgacttttt tcaaaaaata catttataaa attttttttc tttgccttga
     6601 tagttttact acaaggtgcc tggatgagac tttctctgaa tttgtcttgc ttggggttca
     6661 tagaatctgt gacttgatgt ctttcatgag ttttgaaaaa tgctagccat tatctcttaa
     6721 atattgctat tactctactc cctcttctct ttcagatatt tcagttacac caatggccaa
     6781 tgtttgctcg tgtctcatat gtctcttgtt ctagtttctg gatttgtatt cttttttcct
     6841 tttcacattc agtctggata ttttctgctg acctatattc cagttcacta ataatgcttt
     6901 tcactgtatc taatttgctt ataaatagaa aaccattgat tgagttatta atttcagtta
     6961 tagaatagcc agtgtagact ccaatgcttg gctccacttc tccacttttt cacctatttt
     7021 tttcaccatc ttccattttc ttcaacacac cagtcagagt cgtttttaaa gacattttaa
     7081 acacctcagt ggcctgtaga tcttatcttc tgttttttgt ttctttttaa tcttagtttt
     7141 ttggcacact tggagggttt tgattgaatg ctagacatag tattcaggaa ggcagagagg
     7201 attttttttt aagtcagatt ttttgaggta taatttaata cagtaaaatt cacctatttt
     7261 agttcagttc taagagtttc ctctgtgact tttcctttgg cccatggttt atttaaaatt
     7321 gtgttctttt acttccaaat tatttgggat ttttctagat atctttctgt tcttgatttc
     7381 tggcttacct ctatcagggt cagagaacaa acttaatatg atttcaatta ttttaaattt
     7441 gccaatgttt attttatggc ccagaatatg gtctatgttg gtgaaagttc aatttgaact
     7501 tgaaaagaat atgttttatg ctgttgtcta ctgaaaagtc tatatataaa aaatagatta
     7561 ataaactgat taatagcctg gttcacca
//
