LOCUS       NM_014824               4710 bp    mRNA    linear   PRI 09-FEB-2025
DEFINITION  Homo sapiens FCH and double SH3 domains 2 (FCHSD2), mRNA.
ACCESSION   NM_014824
VERSION     NM_014824.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4710)
  AUTHORS   Frisby,D., Murakonda,A.B., Ashraf,B., Dhawan,K., Almeida-Souza,L.,
            Naslavsky,N. and Caplan,S.
  TITLE     Endosomal actin branching, fission, and receptor recycling require
            FCHSD2 recruitment by MICAL-L1
  JOURNAL   Mol Biol Cell 35 (11), ar144 (2024)
   PUBMED   39382837
  REMARK    GeneRIF: Endosomal actin branching, fission, and receptor recycling
            require FCHSD2 recruitment by MICAL-L1.
REFERENCE   2  (bases 1 to 4710)
  AUTHORS   Zhai,X., Shen,Y., Zhang,X., Li,T., Lu,Q. and Xu,Z.
  TITLE     FCHSD2 cooperates with CDC42 and N-WASP to regulate cell protrusion
            formation
  JOURNAL   Biochim Biophys Acta Mol Cell Res 1869 (1), 119134 (2022)
   PUBMED   34520816
  REMARK    GeneRIF: FCHSD2 cooperates with CDC42 and N-WASP to regulate cell
            protrusion formation.
REFERENCE   3  (bases 1 to 4710)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   4  (bases 1 to 4710)
  AUTHORS   Xiao,G.Y. and Schmid,S.L.
  TITLE     FCHSD2 controls oncogenic ERK1/2 signaling outcome by regulating
            endocytic trafficking
  JOURNAL   PLoS Biol 18 (7), e3000778 (2020)
   PUBMED   32678845
  REMARK    GeneRIF: FCHSD2 controls oncogenic ERK1/2 signaling outcome by
            regulating endocytic trafficking.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4710)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (bases 1 to 4710)
  AUTHORS   Taylor,T.D., Noguchi,H., Totoki,Y., Toyoda,A., Kuroki,Y., Dewar,K.,
            Lloyd,C., Itoh,T., Takeda,T., Kim,D.W., She,X., Barlow,K.F.,
            Bloom,T., Bruford,E., Chang,J.L., Cuomo,C.A., Eichler,E.,
            FitzGerald,M.G., Jaffe,D.B., LaButti,K., Nicol,R., Park,H.S.,
            Seaman,C., Sougnez,C., Yang,X., Zimmer,A.R., Zody,M.C.,
            Birren,B.W., Nusbaum,C., Fujiyama,A., Hattori,M., Rogers,J.,
            Lander,E.S. and Sakaki,Y.
  TITLE     Human chromosome 11 DNA sequence and analysis including novel gene
            identification
  JOURNAL   Nature 440 (7083), 497-500 (2006)
   PUBMED   16554811
REFERENCE   7  (bases 1 to 4710)
  AUTHORS   Katoh,M. and Katoh,M.
  TITLE     Identification and characterization of human FCHSD1 and FCHSD2
            genes in silico
  JOURNAL   Int J Mol Med 13 (5), 749-754 (2004)
   PUBMED   15067381
REFERENCE   8  (bases 1 to 4710)
  AUTHORS   Coyle,I.P., Koh,Y.H., Lee,W.C., Slind,J., Fergestad,T.,
            Littleton,J.T. and Ganetzky,B.
  TITLE     Nervous wreck, an SH3 adaptor protein that interacts with Wsp,
            regulates synaptic growth in Drosophila
  JOURNAL   Neuron 41 (4), 521-534 (2004)
   PUBMED   14980202
REFERENCE   9  (bases 1 to 4710)
  AUTHORS   Ohno,H., Hirabayashi,S., Kansaku,A., Yao,I., Tajima,M.,
            Nishimura,W., Ohnishi,H., Mashima,H., Fujita,T., Omata,M. and
            Hata,Y.
  TITLE     Carom: a novel membrane-associated guanylate kinase-interacting
            protein with two SH3 domains
  JOURNAL   Oncogene 22 (52), 8422-8431 (2003)
   PUBMED   14627983
REFERENCE   10 (bases 1 to 4710)
  AUTHORS   Petitjean,C., Scheydeker,J.L., Suinat,J.L. and Rendoing,J.
  TITLE     [Pulmonary edema in hangings]
  JOURNAL   Ann Anesthesiol Fr 16 Spec No 2-3, 57-65 (1975)
   PUBMED   9873
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP002455.4, AP004241.2 and AP002381.3.
            
            On Nov 23, 2018 this sequence version replaced NM_014824.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803616.8584.1,
                                           SRR1803614.240764.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000409418.9/ ENSP00000386722.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-462               AP002455.4         20761-21222         c
            463-560             AP002455.4         18935-19032         c
            561-606             AP004241.2         113185-113230       c
            607-683             AP004241.2         45299-45375         c
            684-828             AP004241.2         30480-30624         c
            829-962             AP004241.2         18454-18587         c
            963-1017            AP004241.2         14552-14606         c
            1018-1146           AP004241.2         13578-13706         c
            1147-1269           AP002381.3         139752-139874       c
            1270-1365           AP002381.3         120467-120562       c
            1366-1482           AP002381.3         107753-107869       c
            1483-1587           AP002381.3         105394-105498       c
            1588-1749           AP002381.3         85789-85950         c
            1750-1884           AP002381.3         67679-67813         c
            1885-1968           AP002381.3         61373-61456         c
            1969-2146           AP002381.3         61075-61252         c
            2147-2367           AP002381.3         60545-60765         c
            2368-2497           AP002381.3         59378-59507         c
            2498-2580           AP002381.3         58801-58883         c
            2581-4710           AP002381.3         54669-56798         c
FEATURES             Location/Qualifiers
     source          1..4710
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q13.4"
     gene            1..4710
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /note="FCH and double SH3 domains 2"
                     /db_xref="GeneID:9873"
                     /db_xref="HGNC:HGNC:29114"
                     /db_xref="MIM:617556"
     exon            1..462
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     CDS             442..2664
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /note="SH3 multiple domains 3; FCH and double SH3 domains
                     protein 2; carom; SH3 multiple domains protein 3; nervous
                     wreck homolog; protein nervous wreck 1"
                     /codon_start=1
                     /product="F-BAR and double SH3 domains protein 2"
                     /protein_id="NP_055639.2"
                     /db_xref="CCDS:CCDS8218.2"
                     /db_xref="GeneID:9873"
                     /db_xref="HGNC:HGNC:29114"
                     /db_xref="MIM:617556"
                     /translation="MQPPPRKVKVTQELKNIQVEQMTKLQAKHQAECDLLEDMRTFSQ
                     KKAAIEREYAQGMQKLASQYLKRDWPGVKADDRNDYRSMYPVWKSFLEGTMQVAQSRM
                     NICENYKNFISEPARTVRSLKEQQLKRCVDQLTKIQTELQETVKDLAKGKKKYFETEQ
                     MAHAVREKADIEAKSKLSLFQSRISLQKASVKLKARRSECNSKATHARNDYLLTLAAA
                     NAHQDRYYQTDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQAVQNTFQFLLENSSK
                     VVRDYNLQLFLQENAVFHKPQPFQFQPCDSDTSRQLESETGTTEEHSLNKEARKWATR
                     VAREHKNIVHQQRVLNDLECHGAAVSEQSRAELEQKIDEARENIRKAEIIKLKAEARL
                     DLLKQIGVSVDTWLKSAMNQVMEELENERWARPPAVTSNGTLHSLNADTEREEGEEFE
                     DNMDVFDDSSSSPSGTLRNYPLTCKVVYSYKASQPDELTIEEHEVLEVIEDGDMEDWV
                     KARNKVGQVGYVPEKYLQFPTSNSLLSMLQSLAALDSRSHTSSNSTEAELVSGSLNGD
                     ASVCFVKALYDYEGQTDDELSFPEGAIIRILNKENQDDDGFWEGEFNGRIGVFPSVLV
                     EELSASENGDTPWMREIQISPSPKPHASLPPLPLYDQPPSSPYPSPDKRSSLYFPRSP
                     SANEKSLHAESPGFSQASRHTPETSYGKLRPVRAAPPPPTQNHRRPAEKIEDVEITLV
                     "
     exon            463..560
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            561..606
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            607..683
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            684..828
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            829..962
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1017
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            1018..1146
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            1147..1269
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1365
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1482
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            1483..1587
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            1588..1749
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            1750..1884
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            1885..1968
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            1969..2146
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            2147..2367
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            2368..2497
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            2498..2580
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     exon            2581..4710
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4692..4697
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /note="hexamer: AATAAA"
     polyA_site      4710
                     /gene="FCHSD2"
                     /gene_synonym="NWK; NWK1; SH3MD3"
                     /note="major polyA site"
ORIGIN      
        1 agcgagggcc gggccgcctg agtgggtggg gtgggggccg ctgcgtccgc cgggagcggc
       61 ggcgcaggcg gccgaccggg agcgcggaca acgcggctgc ggctaacccg ccgcccggcc
      121 ggctgagacc ctcgcgcccc tgctcctggg gcccccgccc cctcgccgtc tccgcctcct
      181 tcctcacaca cccccgggcc gcccgggccg cccgggcccc aagccttccc ggtgctcctc
      241 cctcgtctcc tcacactcgc tctctggctg gggtccgcct gccgcccgct ggcctgctcc
      301 ctccggggca agtcttgctt cttaagcgct cctttcacac acgcgcgcgc tcgctgggcc
      361 gtcccctcct ctccggccct cctcctcctc ctggtccttg ctaacgctgc cgtcggggag
      421 gattgatgtc ccttcagcat catgcagccg ccgccgagga aggtgaaagt tacacaagaa
      481 ctgaaaaaca ttcaagttga gcagatgaca aaacttcaag ccaaacatca agcagaatgt
      541 gatttgcttg aagatatgag gacattcagt cagaagaagg ctgctattga aagagagtat
      601 gcacagggta tgcagaagtt ggctagtcaa tacctgaaga gagattggcc tggagtaaaa
      661 gctgatgatc ggaatgatta caggagcatg tatcccgttt ggaaatcttt tctcgaggga
      721 acaatgcagg tagcccagtc tcggatgaat atatgtgaaa actataaaaa cttcatttct
      781 gagcctgcaa ggacagtgag aagcttaaaa gaacagcaac taaaaaggtg tgtggaccag
      841 ttgacaaaga tccaaactga attacaagag acagtgaaag atttagctaa aggcaaaaag
      901 aaatactttg agactgaaca gatggctcat gcagtacgag agaaagctga catcgaggca
      961 aaatctaaac ttagtctttt tcaatcaaga atcagtttac agaaggcaag tgtaaagtta
     1021 aaagcccggc gatctgagtg taattccaaa gctacccacg caaggaatga ttatcttctt
     1081 accctagcgg cagcaaatgc acatcaggat cgctactatc aaacagattt agttaacatt
     1141 atgaaggctc ttgatggaaa tgtgtatgat catctcaagg attatttaat agccttcagc
     1201 cggactgagc tagaaacatg ccaagctgtg cagaacacat tccagttttt attagaaaac
     1261 tccagcaagg tggtccggga ctacaatctt cagctgtttt tgcaagaaaa cgctgtattt
     1321 cacaaacccc agcccttcca gttccagcct tgtgacagtg atactagccg acagttagaa
     1381 tcagaaactg ggaccacaga ggagcacagt ctaaataagg aagctcgaaa atgggccaca
     1441 cgtgtggcac gtgagcataa aaacattgtt caccaacaac gggttctaaa tgatctggag
     1501 tgtcatggag ctgctgtatc agaacaaagc cgagcagagc tagaacagaa aatagatgaa
     1561 gctagagaaa atattcgtaa agcagagata attaaattga aagctgaagc ccggttggac
     1621 ctgctaaagc agattggtgt ttctgtggac acatggctaa agagtgccat gaaccaagta
     1681 atggaagaac tggaaaatga gcgatgggcc cgccctcctg cagtgaccag taatggcact
     1741 ttacactcgc ttaatgcaga taccgaaaga gaagaaggcg aagagtttga agataacatg
     1801 gatgttttcg atgacagcag ttccagccct tctggcacct taagaaatta tccactcacc
     1861 tgcaaagttg tttattccta caaggcttct caaccagatg agttgaccat tgaggaacat
     1921 gaggtgttag aagtgattga agatggagat atggaagact gggtaaaggc tcgaaataaa
     1981 gttggccaag tgggttatgt gccagaaaag tacctacagt ttcccacctc gaacagcctc
     2041 ctgagcatgc tgcagtccct ggccgctttg gacagtcggt cacacacgtc cagcaattcc
     2101 acggaagcag aactcgtttc aggcagcctc aacggagatg ccagtgtatg ttttgtgaaa
     2161 gcactttatg attatgaggg ccagacagat gatgagttat cttttcctga gggagcaata
     2221 atccgtatct tgaacaaaga aaaccaagat gatgatggct tctgggaagg ggaattcaat
     2281 gggcgtattg gagttttccc atcggtgcta gtggaagaac tttcagcctc agaaaatggt
     2341 gacactccat ggatgagaga gattcagatc tctccttccc ccaagccaca cgcctccctg
     2401 cctccactgc cgttgtacga ccagcctccc agcagcccct accccagccc agataagagg
     2461 agctccctgt actttccccg gtctccttca gcaaacgaaa aaagccttca tgctgagtca
     2521 ccaggattct cacaggcatc aaggcatact cctgagacct catatggcaa actgcgacct
     2581 gtccgggcag ctccccctcc acctacacag aatcaccgaa ggccagcaga gaagattgaa
     2641 gatgtggaaa tcacactggt gtgatgatgg gcttgcccat ccattactgc tacaatcaag
     2701 gccaggcttg gagtttggcc agtcttgttt tttaggcacc tttgcatgat gatgactctt
     2761 gaacagagca aaaaacaagg aggattatgt gtgactgggt ggcctggtag actcctccca
     2821 cgttttgaat atttcgtgcc tttttttttt gttgtcattt tctatgtcat ttctcctacc
     2881 atagcacaaa tcctagcgga ccctaggagc aaagaggggg gcagccctca tgcctaacag
     2941 tggtctgttt ttatatgaga ctcaagaaca ggcctcattc cagggcacag tccctaaatt
     3001 actgatcatg tgcactcgta cagtatatta ctgtgaccac aaggatgtgg caaagattct
     3061 catctttctt caagtggctt ttgctcatct gattgagaat taatcagatc atgttggcta
     3121 cataaggaaa cagaaggagg gatttcagga gaggctggct cctccccaag gttagtcccc
     3181 agactgagaa agtgaaacct tattgggaaa aattggactg ccctgaattt agcaccaatt
     3241 gcattaacgc acatctcttc cacaactaac agacttaaaa taacagtgtc cttcgtatta
     3301 atatctgtgc cattcattta gaattagcag agctaatatg gaggggctga actagtagcc
     3361 acatcttgtt catcacatag actaatagaa aggaggctgt ggctaaagca gaaatggaac
     3421 ttccggatct gaaattagcc aatataatgt tcttttgtat ttgggtattt ttcatcttaa
     3481 tttttacagc atatactctt cttaccagta tccttagaat ccaaatgtct agataagttg
     3541 aggacacata cctgcattgt tgagcttctc tactggggac gccccggcat tattttattc
     3601 ccaagccagc agaccggccc agacagccag gctgtggctg gtccagacca actgctatgg
     3661 tggaaaatgc agcttccagg tcccactacc ctgacatttc cgtggaagga agaacctggt
     3721 ggctcgtgga ggaaaccagc tttctatgag aaaggactga aggattgcgc accctgcaca
     3781 agtacagatt gaccaggaaa agacaagtgt cttctgtgtg tcacagggaa agccaggagt
     3841 ggccttctct gcaggccagc aagcctgcag cagcaggtgc ccccacgtca ggtgctgact
     3901 gtctgctgtc cgctcctgta gaaggtaggg agcacaatac ctagggacta agggatgttc
     3961 gccggttgtg gtttgttttt tttttttttc cttggttaag aaatcaaatt tgcagaattt
     4021 aatctacaag ttgtattatg ctttgaaaac tccatccctc ctaagaatct taaaaaactt
     4081 gaaatgctcg ccaaatgtcc ccatgggatt tttgaccaaa agtaaggtga taactgaaga
     4141 aatttttagt tctttgatca cttcagtgac aatacccatt aatgaatctt ctccatgatt
     4201 tggggttttt tttcgttgtt gttttttaca cttcttaacc tgttgatcta tttgaggtct
     4261 tttgtgttta tcaaacttat tcttaagttt aaaaaagaaa ttaaaagggt ggttttttta
     4321 agattttaaa gtttgctaac atattaaaaa tcttcaaatg cttattaaat agagcagttc
     4381 ttgccaccca gtcttgtatt ctgtctttag ctagccaaat tgtccttgaa tttgggtttt
     4441 ccacaacctc aaagggttat ttgaaatctt ttgttgtatt ttaaaatatt ttttggaaga
     4501 gctgctaatt ttattttaaa aaacaaagtt gtgaaaacat gcctcctttt taaaaaataa
     4561 cccctccatc caggatatgg aatccagcac cacagtgcac aggtcagggc tcggagggag
     4621 cctctgtgca gatgtgcttt ctttacagtg gctgtaaaaa gtttgtattt attatgtata
     4681 aaatgttgaa taataaaaaa aatggaatta
//
