LOCUS       XM_017024020            3683 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens F-box and WD repeat domain containing 10
            (FBXW10), transcript variant X13, mRNA.
ACCESSION   XM_017024020
VERSION     XM_017024020.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017024020.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 2% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3683
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..3683
                     /gene="FBXW10"
                     /gene_synonym="Fbw10; HREP; SM25H2; SM2SH2"
                     /note="F-box and WD repeat domain containing 10; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 16 ESTs, 1 long SRA read, 3 Proteins, and 78% coverage
                     of the annotated genomic feature by RNAseq alignments,
                     including 1 sample with support for all annotated introns"
                     /db_xref="GeneID:10517"
                     /db_xref="HGNC:HGNC:1211"
                     /db_xref="MIM:611679"
     CDS             192..2762
                     /gene="FBXW10"
                     /gene_synonym="Fbw10; HREP; SM25H2; SM2SH2"
                     /codon_start=1
                     /product="F-box/WD repeat-containing protein 10 isoform
                     X12"
                     /protein_id="XP_016879509.1"
                     /db_xref="GeneID:10517"
                     /db_xref="HGNC:HGNC:1211"
                     /db_xref="MIM:611679"
                     /translation="MENLESRLKNAPYFRCEKGTDSIPLCRKCETCVLAWKIFSTKEW
                     FCRINDISQRRFLVGILKQLNSLYLLHYFQNILQTTQGKDFIYNRSRINLSKKEGKVV
                     KSSLNQMLDKTVEQKMKEILYWFANSTQWTKANYTLLLLQMCNPKLLLTAANVIRVLF
                     LREENNISGKQGHRQRLEGPRRPEGKASEIWLNQDITDVCFSPEKDHSSKSATSQVYW
                     TAKTQHTSLPLSKAPENEHLLGAASNPEEPWRNSLRCISEMNRLFSGKGDITKPGYDP
                     CNLLVDLDDIRDLSSGFSKYRDFIRYLPIHLSKYILSMLGCMRGFPRHLPSWPSSGVS
                     GSIFFFPGMLDRHTLNKCASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGSYTRGID
                     PNYANKVSIPVPKMVDDGKSMRVKHPKWKLRTKNEYNLWTAYQNEETQQVLIEERNVF
                     CGTYNVRILSDTWDQNRVIHYSGGDLIAVSSNRKIHLLDIIQVKAIPVEFRGHAGSVR
                     ALFLCEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKNRLVSGGRDC
                     QVKVWDVDTGKCLKTFRHKDPILATRINDTYIVSSCERGLVKVWHIAMAQLVKTLSGH
                     EGAVKCLFFDQWHLLSGSTDGLVMAWSMVGKYERCLMAFKHPKEVLDVSLLFLRVISA
                     CADGKIRIYNFLNGNCMKVLKANGRGDPVLSFFIQGNRMVVNTESNVLMFQFEHIKWQ
                     YAVEKTKQKKNKEKEEEKEENSLMEILSKCNIQVHSPRESVSSKQTVIQELLPGKPPK
                     SRVLLKPAKFSSAVLIEELQSQGKSKSPRRDAGHYLCLSLRNWNEYNAWLLPRVTGFP
                     "
ORIGIN      
        1 agacttctgc tggcagttac tgagagagat aggctttcca tccatggcag ccatttactt
       61 ttgctctggg agacgtttgt aatagaaaag gcacaactgg ggtatttatt cattcccccc
      121 gttcctctag tgtttggtgg cgttgccgtt gcaagtgcgc agggctaaaa tggactggtt
      181 atcttaggat catggaaaac ctggaatcaa ggctcaagaa tgccccctat tttcgttgtg
      241 agaagggaac cgattccatc cctctatgcc ggaagtgtga gacgtgtgtc ttagcctgga
      301 agatcttctc taccaaagag tggttctgca ggatcaatga catatcacag aggaggtttc
      361 tagttggcat tctgaagcag ttaaatagct tatatttgtt acactatttc caaaatatcc
      421 ttcagaccac acagggaaag gatttcatct ataacaggtc ccggatcaac ctcagcaaga
      481 aagaggggaa agttgtgaag tcctccttga accaaatgtt ggataaaaca gtagaacaga
      541 agatgaaaga gatcttgtac tggtttgcga acagcaccca gtggaccaag gcgaattata
      601 ctctcttact gctgcagatg tgcaacccca aattactgct cactgctgcc aatgtgatca
      661 gagtcctgtt tctgagagag gagaacaata tctcaggtaa acaaggccac aggcagagac
      721 tagagggccc ccgaagacca gaaggcaagg cttcagaaat ctggctcaat caagacatca
      781 cagatgtgtg tttttcccct gagaaagacc acagctccaa gtctgcgacc tcacaagtct
      841 attggacagc caaaactcag cacacatccc ttcctttgtc caaagcccca gaaaatgaac
      901 acttgcttgg ggcagcatct aaccctgagg aaccatggag gaattcactc cggtgtatat
      961 ccgaaatgaa taggctgttt tctggaaaag gagacataac caagccaggg tacgatccct
     1021 gcaatctatt ggttgacctg gatgacatca gagacctgtc ttctgggttc agcaaatacc
     1081 gagacttcat ccgttacctg cccatccacc tctccaagta cattctaagt atgctggggt
     1141 gtatgagggg atttcccaga cacctcccct cttggcccag ttctggggtt tctgggtcca
     1201 tctttttttt tccaggaatg ctggatagac acaccctgaa caagtgcgcc tctgtgagcc
     1261 agcactgggc cgccatggct caacaggtca agatggactt gtcagcgcac ggcttcattc
     1321 agaaccagat taccttcttg caggggtcct acacaagagg aattgatcct aattatgcca
     1381 ataaggtttc tatcccagtt cctaaaatgg tagatgacgg gaagagcatg cgtgtgaaac
     1441 atccgaagtg gaagctgaga acgaagaatg agtacaacct gtggactgca taccagaacg
     1501 aggaaacgca gcaggtcctg atagaggaga gaaatgtttt ctgtgggacc tacaatgttc
     1561 gcattctctc tgacacgtgg gatcaaaacc gagtcatcca ctattccggg ggagatctga
     1621 tagctgtgtc atctaatcga aagatccatc ttctggacat catacaagtg aaagcgatac
     1681 ccgttgaatt ccgaggccat gctgggagtg tccgggccct cttcctgtgt gaggaggaaa
     1741 actttctcct aagcgggagc tatgacctaa gtatcagata ctgggatctg aaaagtgggg
     1801 tttgcacacg aatcttcggt ggtcaccagg ggactatcac ttgcatggac ttgtgtaaga
     1861 acaggctcgt atctggagga agagattgcc aggtaaaagt atgggatgta gacacaggga
     1921 agtgcctgaa gacgtttaga cacaaagacc ccatcttggc caccaggatc aatgatacct
     1981 acattgtgag cagctgtgag cgagggctgg tgaaagtgtg gcacattgcc atggcccagt
     2041 tggtaaagac tctcagtggc catgagggag ccgtgaaatg cctgttcttt gaccagtggc
     2101 atctcctctc aggaagtact gatggcctgg tcatggcctg gagcatggtg gggaagtacg
     2161 agcgctgcct gatggccttc aagcatccca aggaggtgct cgacgtgtcc cttctcttcc
     2221 tccgggtcat cagcgcctgt gcagatggca agatccgaat ttacaatttc ctcaacggga
     2281 actgtatgaa ggtgttaaaa gccaatggca gaggtgatcc tgtgctgtcc ttctttattc
     2341 agggcaacag gatggtggtc aacacagaga gcaatgttct catgttccag tttgagcaca
     2401 taaagtggca gtatgccgtg gaaaaaacga aacaaaagaa gaataaggag aaagaggagg
     2461 aaaaagaaga aaatagtctc atggaaattc tctctaagtg taatattcag gttcacagcc
     2521 caagagagtc tgtatccagt aaacaaactg tgatccaaga gctcctacca ggcaaacctc
     2581 ccaagtcccg agtactcctg aagccggcca agttctcttc agcagtgtta atagaggaac
     2641 ttcaaagtca aggaaagtca aaatcacccc gaagagatgc aggccactac ctttgcttgt
     2701 ctttgagaaa ctggaatgaa tacaatgcct ggcttctccc aagagtgact ggttttcctt
     2761 aattgtccct tttctgactt gaggccacag agggagaacc tttctaagca gatgatgtgg
     2821 agaaagcaca aaaacaagga caattggaaa ctcctggaaa actgcccagt cacccaaaga
     2881 aaaagtcttg gaaaatccct atgtcacctg accaattcct cctgactgtt agcgccctgc
     2941 agcacgccca taattccggg gaatttgcct atccctgtag gccccaaaca gaaattactg
     3001 atgtctgggg accttcaatt tcatacccaa ggaaggtctt gaatttcaaa ggaaaatcaa
     3061 tccaacgtgc agttgatcgg ttgagattga gcaatcctcc tatagatgtg aaacgaacca
     3121 gtattcccct tgaaatccag aaactgcagc ccaacttgaa gatctctttg cacagtccta
     3181 gagtccagtc caccataccc cagcccatga ttatccgctc caggttctct ggcagcttaa
     3241 agggtggaga ccaagtgacc agttcaattg aaagggctgt gtgcagtacg ggtcccctga
     3301 ccagtatgca ggtcattaaa ccaaaccgca tgctagctcc acaagtgggc acagccaccc
     3361 tgtctcttaa gaaagaacgg cctcgcatct atacagccct tgatcctttt agagtgaaca
     3421 ctgagttcgt gctgttgacc gtgaaggagg agaaggagca ccaggaagcc aagatgaagg
     3481 aatatcaggc cagggagtcc actggagtgg ttgatccagg aaaagtcagc aaagctgcat
     3541 ggatcaggaa gatcaaaggc ctgcctattg ataatttcac gaagcaaggg aaaacagcgg
     3601 cccctgaact tggacaaaat gtatttatct aaaccagcct tgggaaatta caatgtttta
     3661 caataaacag aaagccaagc gga
//
