LOCUS       NM_012347               4438 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens F-box protein 9 (FBXO9), transcript variant 1, mRNA.
ACCESSION   NM_012347
VERSION     NM_012347.4
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4438)
  AUTHORS   Hussain,S., Dong,J., Ma,X., Li,J., Chen,S., Clement,A. and Liu,H.
  TITLE     F-box only protein 9 and its role in cancer
  JOURNAL   Mol Biol Rep 49 (2), 1537-1544 (2022)
   PUBMED   35025031
  REMARK    GeneRIF: F-box only protein 9 and its role in cancer.
            Review article
REFERENCE   2  (bases 1 to 4438)
  AUTHORS   Lai,Y., Li,X., Li,T., Nyunoya,T., Chen,K., Kitsios,G.D.,
            Nouraie,S.M., Zhang,Y., McVerry,B.J., Lee,J.S., Mallampalli,R.K.
            and Zou,C.
  TITLE     Endotoxin stabilizes protein arginine methyltransferase 4 (PRMT4)
            protein triggering death of lung epithelia
  JOURNAL   Cell Death Dis 12 (9), 828 (2021)
   PUBMED   34480022
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4438)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (bases 1 to 4438)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (bases 1 to 4438)
  AUTHORS   Hauri,S., Comoglio,F., Seimiya,M., Gerstung,M., Glatter,T.,
            Hansen,K., Aebersold,R., Paro,R., Gstaiger,M. and Beisel,C.
  TITLE     A High-Density Map for Navigating the Human Polycomb Complexome
  JOURNAL   Cell Rep 17 (2), 583-595 (2016)
   PUBMED   27705803
REFERENCE   6  (bases 1 to 4438)
  AUTHORS   Jin,J., Cardozo,T., Lovering,R.C., Elledge,S.J., Pagano,M. and
            Harper,J.W.
  TITLE     Systematic analysis and nomenclature of mammalian F-box proteins
  JOURNAL   Genes Dev 18 (21), 2573-2580 (2004)
   PUBMED   15520277
REFERENCE   7  (bases 1 to 4438)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
REFERENCE   8  (bases 1 to 4438)
  AUTHORS   Scanlan,M.J., Gordan,J.D., Williamson,B., Stockert,E., Bander,N.H.,
            Jongeneel,V., Gure,A.O., Jager,D., Jager,E., Knuth,A., Chen,Y.T.
            and Old,L.J.
  TITLE     Antigens recognized by autologous antibody in patients with
            renal-cell carcinoma
  JOURNAL   Int J Cancer 83 (4), 456-464 (1999)
   PUBMED   10508479
REFERENCE   9  (bases 1 to 4438)
  AUTHORS   Winston,J.T., Koepp,D.M., Zhu,C., Elledge,S.J. and Harper,J.W.
  TITLE     A family of mammalian F-box proteins
  JOURNAL   Curr Biol 9 (20), 1180-1182 (1999)
   PUBMED   10531037
REFERENCE   10 (bases 1 to 4438)
  AUTHORS   Cenciarelli,C., Chiaur,D.S., Guardavaccaro,D., Parks,W., Vidal,M.
            and Pagano,M.
  TITLE     Identification of a family of human F-box proteins
  JOURNAL   Curr Biol 9 (20), 1177-1179 (1999)
   PUBMED   10531035
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AF176704.1, BC000650.2 and
            AL031178.1.
            
            On Nov 1, 2006 this sequence version replaced NM_012347.3.
            
            Summary: This gene encodes a member of the F-box protein family
            which is characterized by an approximately 40 amino acid motif, the
            F-box. The F-box proteins constitute one of the four subunits of
            the ubiquitin protein ligase complex called SCFs
            (SKP1-cullin-F-box), which function in phosphorylation-dependent
            ubiquitination. The F-box proteins are divided into 3 classes: Fbws
            containing WD-40 domains, Fbls containing leucine-rich repeats, and
            Fbxs containing either different protein-protein interaction
            modules or no recognizable motifs. The protein encoded by this gene
            belongs to the Fbxs class. Alternative splicing of this gene
            generates at least 3 transcript variants diverging at the 5'
            terminus. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (1) is shortest transcript yet it
            encodes the longest protein (isoform 1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF176704.1, SRR1803612.473599.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-716               AF176704.1         1-716
            717-1453            BC000650.2         844-1580
            1454-4438           AL031178.1         74719-77703
FEATURES             Location/Qualifiers
     source          1..4438
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p12.1"
     gene            1..4438
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /note="F-box protein 9"
                     /db_xref="GeneID:26268"
                     /db_xref="HGNC:HGNC:13588"
                     /db_xref="MIM:609091"
     exon            1..171
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..1395
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /note="isoform 1 is encoded by transcript variant 1; F-box
                     protein Fbx9; F-box only protein 9; cross-immune reaction
                     antigen 1; renal carcinoma antigen NY-REN-57"
                     /codon_start=1
                     /product="F-box only protein 9 isoform 1"
                     /protein_id="NP_036479.1"
                     /db_xref="CCDS:CCDS55023.1"
                     /db_xref="GeneID:26268"
                     /db_xref="HGNC:HGNC:13588"
                     /db_xref="MIM:609091"
                     /translation="MPDIIWVFPPQAEAEEDCHSDTVRADDDEENESPAETDLQAQLQ
                     MFRAQWMFELAPGVSSSNLENRPCRAARGSLQKTSADTKGKQEQAKEEKARELFLKAV
                     EEEQNGALYEAIKFYRRAMQLVPDIEFKITYTRSPDGDGVGNSYIEDNDDDSKMADLL
                     SYFQQQLTFQESVLKLCQPELESSQIHISVLPMEVLMYIFRWVVSSDLDLRSLEQLSL
                     VCRGFYICARDPEIWRLACLKVWGRSCIKLVPYTSWREMFLERPRVRFDGVYISKTTY
                     IRQGEQSLDGFYRAWHQVEYYRYIRFFPDGHVMMLTTPEEPQSIVPRLRTRNTRTDAI
                     LLGHYRLSQDTDNQTKVFAVITKKKEEKPLDYKYRYFRRVPVQEADQSFHVGLQLCSS
                     GHQRFNKLIWIHHSCHITYKSTGETAVSAFEIDKMYTPLFFARVRSYTAFSERPL"
     exon            172..330
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /inference="alignment:Splign:2.1.0"
     exon            331..388
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /inference="alignment:Splign:2.1.0"
     exon            389..488
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /inference="alignment:Splign:2.1.0"
     exon            489..619
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /inference="alignment:Splign:2.1.0"
     exon            620..734
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /inference="alignment:Splign:2.1.0"
     exon            735..853
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /inference="alignment:Splign:2.1.0"
     exon            854..944
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /inference="alignment:Splign:2.1.0"
     exon            945..1040
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /inference="alignment:Splign:2.1.0"
     exon            1041..1134
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1286
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..4438
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1916..1921
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /note="hexamer: AATAAA"
     polyA_site      1938
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /note="major polyA site"
     regulatory      4417..4422
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
                     /note="hexamer: AATAAA"
     polyA_site      4438
                     /gene="FBXO9"
                     /gene_synonym="dJ341E18.2; FBX9; NY-REN-57; VCIA1"
ORIGIN      
        1 aaagtggctg aatgagaaat gtagattgca gagggcaact ggtgtgttta tatgcctgac
       61 attatttggg ttttcccccc tcaggcagaa gctgaggaag attgtcattc tgatactgtc
      121 agagcagatg atgatgaaga aaatgaaagt cctgctgaaa cagatctgca ggcacaactc
      181 cagatgttcc gagctcagtg gatgtttgaa cttgctccag gtgtaagctc tagcaattta
      241 gaaaatcgac cttgcagagc agcaagaggc tctctccaga aaacatcggc agataccaaa
      301 ggaaaacaag aacaggcaaa agaagaaaag gctcgagaac tcttcctaaa agcagtagaa
      361 gaagaacaaa atggagctct ctatgaagcc atcaagtttt atcgtagggc tatgcaactt
      421 gtacctgata tagagttcaa gattacttat acccggtctc cagatggtga tggcgttgga
      481 aacagctaca ttgaagataa tgatgatgac agcaaaatgg cagatctctt gtcctacttc
      541 cagcagcaac tcacatttca ggagtctgtg cttaaactgt gtcagcctga gcttgagagc
      601 agtcagattc acatatcagt gctgccaatg gaggtcctga tgtacatctt ccgatgggtg
      661 gtgtctagtg acttggacct cagatcattg gagcagttgt cgctggtgtg cagaggattc
      721 tacatctgtg ccagagaccc tgaaatatgg cgtctggcct gcttgaaagt ttggggcaga
      781 agctgtatta aacttgttcc gtacacgtcc tggagagaga tgtttttaga acggcctcgt
      841 gttcggtttg atggcgtgta tatcagtaaa accacatata ttcgtcaagg ggaacagtct
      901 cttgatggtt tctatagagc ctggcaccaa gtggaatatt acaggtacat aagattcttt
      961 cctgatggcc atgtgatgat gttgacaacc cctgaagagc ctcagtccat tgttccacgt
     1021 ttaagaacta ggaataccag gactgatgca attctactgg gtcactatcg cttgtcacaa
     1081 gacacagaca atcagaccaa agtatttgct gtaataacta agaaaaaaga agaaaaacca
     1141 cttgactata aatacagata ttttcgtcgt gtccctgtac aagaagcaga tcagagtttt
     1201 catgtggggc tacagctatg ttccagtggt caccagaggt tcaacaaact catctggata
     1261 catcattctt gtcacattac ttacaaatca actggtgaga ctgcagtcag tgcttttgag
     1321 attgacaaga tgtacacccc cttgttcttc gccagagtaa ggagctacac agctttctca
     1381 gaaaggcctc tgtagagcct caagtccagt cctctatcac ttttgcatga attaaagtat
     1441 atagcgcaaa agagcaccta agttataaat gtgtgtgtgt gcgtgtgtgt gtatatatat
     1501 atatatatat atatatatat atatatatat atatatatat ggaattggaa cttattttaa
     1561 attgttggag ttcttttaag aagaatataa attgattatt ttttttattt aaagggatag
     1621 ttgattcctg gggtgttttg aaattaagtt ggaattaagt tgcttaagca tatttatgtt
     1681 gtgagaaacc ttaatatgag gtttatcatg ccctttttca agcagattta tgagcagatt
     1741 tctgtcacat aagtcgtctt ctgcttgagt atcctaatat ttcaatgcat caggggagcg
     1801 ctccactgga taagcatttt atttcccgca tggcataatg tttttgcact aaaggctcaa
     1861 agtgtgagaa cctgttctgg atttgtttga aattatttca ccaataaaga tcataaataa
     1921 atgtttcttt caagaaaata tatttggatg gcctttttaa agtaacagga tatttaataa
     1981 gagtcctaga tagccagcgg agactttaag aatcattgcc tctagctggg tgtggtggca
     2041 tgcacctgta gtcccagcta tttgggaggc tgatgcagga gaatagctta agcccaggaa
     2101 tttgagtctg ggagtttgag tccagcatgg gcaacataac aagaccccat cccttattaa
     2161 aagaaaaaaa aataattcct catttcatca ttggtcttta tatgtagcca caaacactga
     2221 cctcatgtag gcaccttacc aatatatgac attaagtgag agtgaatccc ttaggactgg
     2281 aacacttcaa gctcaaccaa ctgactcagt tgtcattctt cacaaaagaa tagtagagga
     2341 tcatgtaaac ctgagcctaa ctcttgttcc agtatgaaag ttgggggaga gcaccagcca
     2401 cctaggaaaa ctgtatgtta cctttttact caaaggagtc ccccctgccc agtaacagtc
     2461 ctattagtgt ttaatttcag agtttgtgtc tggtagacct ctacctgatt cagatttggt
     2521 tttgttgttt caaccatagt tagagacaaa ttctcatgta ctttcagaaa tcaatatctg
     2581 cagccactgt tacttttaat tgacattaag agacacttca taggttccca caattcagta
     2641 tgggataggc tttttaaaaa gcacatacag accaggcgtg gtggctcatg cctataatcc
     2701 cagcactttg ggaggctaag acaggcagat cacctgagct caggagtcca agaccagcct
     2761 gggcaacatg gcaaaacacc gtctctacaa aaaaaaaaaa aaaaaaaatt agccaagtac
     2821 agtggggcac acctatagtc gcagctactt gggaggctgg ggcaggagaa ttgcctgagc
     2881 ctgggaagtg gaagttgcag tgagccaaga tcgtgccatt ccactccagc ctgagcaaca
     2941 cagtgagacc ctatctcaaa aaaataatga tgatagtaca cgttatgtta aaggtgaaat
     3001 gtgcatacag aaggaagaga gttggccagg tgtggtgact cacacctata atcccaatac
     3061 tttgggaggc caaggcagga ggattgcttg aggtcaggag ttttagacca gcctggacaa
     3121 catagcaaga cctcatctct tctaaaaatt aaaaaaaaaa aaaataggca tggtggtaca
     3181 cacctgtggt cccagctagt tgggaggcta aggcaggagg atcacttagc caggaggctg
     3241 aggctacagt gagccaagat tgcaccactg tgctccagcc tgggtgagaa agcgagaccc
     3301 tgtctcaaaa aagaaaaaaa agagaggttg gccttttgta gcaatctgag aagtgtgttt
     3361 ttcaagttgg aaaggaagga gaaaagcaac ttgcctaaga taaggtagct cttcatgata
     3421 tgactgttat ttctgatata caaataaata gaacatgatt aggacatagt caaatatagc
     3481 tagaaaaata tattcctaag gaaagtgaga tttgaggagt ccctgttgtt ctgcaacatc
     3541 cctagattga atgatctgtt gcagatggtg gataccaagt tcaaatttaa agatttcttt
     3601 gtaagcagta aagtgacttt cacttattta acttagaact ggaaaaagta acttttttcc
     3661 agattacatt ttctgtatat ttgtaaaatg caaaagcaat atatatttgt tgtgagaaaa
     3721 ttagaatata cagataaaat aaaatttaaa aaaacaccca aagataacca gaagaaaatt
     3781 tttgctatgt aacctttttc ttctggtctt tgcaaatcct gccgtagaaa ctttttaact
     3841 tcaggagtgt ccttcctttg ctctattagg acattacaga aaccaatact atgaaaagct
     3901 gacagcagta tctggattaa ctttttaaaa acaatgaaag cattttacag aaattacatt
     3961 tcagatcgtg ctggaactgt gttcagaaga tatcctcaga gggaatctgg cctgagcacc
     4021 atcatgttta attgcctcct cctgtcttgc attttcctcc cagccccctt cctacccctt
     4081 agcagagggc caggtgaggg tgcttggggc ccatgggggc tgggagtgta gacttcagtt
     4141 acacccccag cccccagggg aaagcattag ccttgaatcc tcaatcccag gccctctact
     4201 aaccactctc aacctatggt atttatcttt tgattattct gtgcatctat aaaaatggga
     4261 ttatattgta cagaatgctt tgtaagcttt ctctccccac ataagaatgc cctgtaagca
     4321 ttttgttaaa tatttttaat gactttagag tccaacttta tactcctctt tacgcatttt
     4381 ggttttctaa tttaatggta gtgtaaacgt ttttggaata aacattcctg tggctaaa
//
