LOCUS       NM_018994               6227 bp    mRNA    linear   PRI 07-FEB-2025
DEFINITION  Homo sapiens F-box protein 42 (FBXO42), mRNA.
ACCESSION   NM_018994 XM_048774
VERSION     NM_018994.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6227)
  AUTHORS   Zhou,J., Li,Q., Deng,X., Peng,L., Sun,J., Zhang,Y. and Du,Y.
  TITLE     Comprehensive analysis identifies ubiquitin ligase FBXO42 as a
            tumor-promoting factor in neuroblastoma
  JOURNAL   Sci Rep 14 (1), 18697 (2024)
   PUBMED   39134694
  REMARK    GeneRIF: Comprehensive analysis identifies ubiquitin ligase FBXO42
            as a tumor-promoting factor in neuroblastoma.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6227)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 6227)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   4  (bases 1 to 6227)
  AUTHORS   Nagler,A., Vredevoogd,D.W., Alon,M., Cheng,P.F., Trabish,S.,
            Kalaora,S., Arafeh,R., Goldin,V., Levesque,M.P., Peeper,D.S. and
            Samuels,Y.
  TITLE     A genome-wide CRISPR screen identifies FBXO42 involvement in
            resistance toward MEK inhibition in NRAS-mutant melanoma
  JOURNAL   Pigment Cell Melanoma Res 33 (2), 334-344 (2020)
   PUBMED   31549767
  REMARK    GeneRIF: A genome-wide CRISPR screen identifies FBXO42 involvement
            in resistance toward MEK inhibition in NRAS-mutant melanoma.
REFERENCE   5  (bases 1 to 6227)
  AUTHORS   Freitas,M.J., Silva,J.V., Brothag,C., Regadas-Correia,B.,
            Fardilha,M. and Vijayaraghavan,S.
  TITLE     Isoform-specific GSK3A activity is negatively correlated with human
            sperm motility
  JOURNAL   Mol Hum Reprod 25 (4), 171-183 (2019)
   PUBMED   30824926
REFERENCE   6  (bases 1 to 6227)
  AUTHORS   Li,X., Wang,W., Wang,J., Malovannaya,A., Xi,Y., Li,W., Guerra,R.,
            Hawke,D.H., Qin,J. and Chen,J.
  TITLE     Proteomic analyses reveal distinct chromatin-associated and soluble
            transcription factor complexes
  JOURNAL   Mol Syst Biol 11 (1), 775 (2015)
   PUBMED   25609649
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 6227)
  AUTHORS   Gao,K., Deng,X., Zheng,W., Song,Z., Zhu,A., Xiu,X. and Deng,H.
  TITLE     Genetic analysis of the FBXO42 gene in Chinese Han patients with
            Parkinson's disease
  JOURNAL   BMC Neurol 13, 125 (2013)
   PUBMED   24063688
  REMARK    GeneRIF: The findings of this study suggest that a haplotype of the
            FBXO42 gene might be associated with a higher susceptibility to PD.
            Publication Status: Online-Only
REFERENCE   8  (bases 1 to 6227)
  AUTHORS   Sun,L., Shi,L., Wang,F., Huangyang,P., Si,W., Yang,J., Yao,Z. and
            Shang,Y.
  TITLE     Substrate phosphorylation and feedback regulation in JFK-promoted
            p53 destabilization
  JOURNAL   J Biol Chem 286 (6), 4226-4235 (2011)
   PUBMED   21127074
  REMARK    GeneRIF: Substrate phosphorylation and feedback regulation in
            JFK-promoted p53 destabilization.
REFERENCE   9  (bases 1 to 6227)
  AUTHORS   Sun,L., Shi,L., Li,W., Yu,W., Liang,J., Zhang,H., Yang,X., Wang,Y.,
            Li,R., Yao,X., Yi,X. and Shang,Y.
  TITLE     JFK, a Kelch domain-containing F-box protein, links the SCF complex
            to p53 regulation
  JOURNAL   Proc Natl Acad Sci U S A 106 (25), 10195-10200 (2009)
   PUBMED   19509332
  REMARK    GeneRIF: JFK promotes p53 turnover through assembly of an SCF
            (Skp1-Cul1-F-box) complex, revealing a pathway for the control of
            p53 degradation and providing a link between the SCF complex and
            p53 regulation.
            Erratum:[Proc Natl Acad Sci U S A. 2025 Feb 18;122(7):e2426753122.
            doi: 10.1073/pnas.2426753122.. PMID: 39913193]
REFERENCE   10 (bases 1 to 6227)
  AUTHORS   Jin,J., Cardozo,T., Lovering,R.C., Elledge,S.J., Pagano,M. and
            Harper,J.W.
  TITLE     Systematic analysis and nomenclature of mammalian F-box proteins
  JOURNAL   Genes Dev 18 (21), 2573-2580 (2004)
   PUBMED   15520277
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA488838.1, HY007337.1, BC063864.1, AB037753.1 and AW449773.1.
            
            On Nov 23, 2018 this sequence version replaced NM_018994.2.
            
            Summary: Members of the F-box protein family, such as FBXO42, are
            characterized by an approximately 40-amino acid F-box motif. SCF
            complexes, formed by SKP1 (SKP1A; MIM 601434), cullin (see CUL1;
            MIM 603134), and F-box proteins, act as protein-ubiquitin ligases.
            F-box proteins interact with SKP1 through the F box, and they
            interact with ubiquitination targets through other protein
            interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied
            by OMIM, Dec 2010].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660803.185547.1,
                                           SRR1660803.190047.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2144333, SAMEA2467144
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000375592.8/ ENSP00000364742.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1                 DA488838.1         12-12
            2-258               HY007337.1         1-257
            259-3003            BC063864.1         232-2976
            3004-6226           AB037753.1         2564-5786
            6227-6227           AW449773.1         16-16               c
FEATURES             Location/Qualifiers
     source          1..6227
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.13"
     gene            1..6227
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /note="F-box protein 42"
                     /db_xref="GeneID:54455"
                     /db_xref="HGNC:HGNC:29249"
                     /db_xref="MIM:609109"
     exon            1..226
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /inference="alignment:Splign:2.1.0"
     exon            227..493
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /inference="alignment:Splign:2.1.0"
     CDS             244..2397
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /note="just one F-box and Kelch domain-containing protein"
                     /codon_start=1
                     /product="F-box only protein 42"
                     /protein_id="NP_061867.1"
                     /db_xref="CCDS:CCDS30613.1"
                     /db_xref="GeneID:54455"
                     /db_xref="HGNC:HGNC:29249"
                     /db_xref="MIM:609109"
                     /translation="MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHN
                     RSMSELPEEVLEYILSFLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNI
                     QWESRTYPYPGTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKE
                     WIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKN
                     WWNCIVTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNIS
                     GPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEH
                     GAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQ
                     SPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAA
                     VGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKP
                     ASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAM
                     SSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHH
                     PPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRVKWKVFNSSSVVGPPETSLHTVV
                     QGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR"
     exon            494..610
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /inference="alignment:Splign:2.1.0"
     exon            611..745
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /inference="alignment:Splign:2.1.0"
     exon            746..899
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /inference="alignment:Splign:2.1.0"
     exon            900..1010
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1107
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /inference="alignment:Splign:2.1.0"
     exon            1108..1164
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..1281
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /inference="alignment:Splign:2.1.0"
     exon            1282..6227
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2412
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /note="major polyA site"
     regulatory      2645..2650
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /note="hexamer: GATAAA"
     polyA_site      2668
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /note="major polyA site"
     regulatory      3028..3033
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /note="hexamer: AATAAT"
     polyA_site      3069
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
     regulatory      6205..6210
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
                     /note="hexamer: AATAAA"
     polyA_site      6227
                     /gene="FBXO42"
                     /gene_synonym="Fbx42; JFK"
ORIGIN      
        1 ctgcgctgtc ttctcccggc ctgagcagca gcagctgcgg cggcggcggc gtttgagtgg
       61 aggaagatgg cggctccggg cggctcgggg tcccgccagc tgtgaggagc cccgagcacg
      121 gctgtcgcgg cctgaggcag agcgcctctg ctctggccct gtccctggct ccctcattac
      181 cgtcgccagc ggagcgaacc cgagagcgtg gagcgggctg ggccagctgt tgagtggaat
      241 gtcatggcca gctcctcgga cagtgaagat gacagtttca tggctgtgga ccaggaagaa
      301 actgtgctgg aagggacaat ggatcaagat gaggagcccc acccagtatt ggaggctgag
      361 gagactagac ataataggtc catgtcggag ctgccagaag aggttttgga gtatatcctg
      421 tcctttctct caccgtatca ggaacacaaa actgcggccc ttgtctgcaa acagtggtat
      481 cgacttatca aaggtgtagc ccatcagtgt tatcatggtt tcatgaaggc tgtccaggaa
      541 ggaaacattc agtgggagag ccgtacctat ccttatcctg gaaccccaat cactcagcgc
      601 ttctcgcaca gtgcatgcta ttatgatgct aatcagtcta tgtatgtgtt tggaggctgt
      661 acccagagca gctgcaatgc tgctttcaat gacctctgga gacttgacct aaacagcaaa
      721 gagtggatcc gacctttggc ttcagggtcc tatccttccc ccaaagctgg agcaactctg
      781 gtcgtgtaca aggacttgct agtgctgttt ggtggctgga cgcggccaag cccttatccc
      841 ctacaccagc cagagagatt ctttgatgaa atacacactt actcaccctc taaaaattgg
      901 tggaactgca ttgtgacaac ccatgggcca cctcccatgg ctggccactc ctcctgtgtg
      961 atagatgata aaatgattgt ctttggtggc tctttaggat cccggcaaat gagcaatgat
     1021 gtctgggtcc ttgaccttga gcagtgggcg tggtccaagc cgaacatctc tggccccagt
     1081 cctcatcctc gaggtggcca atctcagatt gtcatagatg atgcaactat cttaatcctc
     1141 ggagggtgtg gcggtcccaa tgctctattc aaggatgctt ggttgttgca catgcattct
     1201 ggtccttggg cctggcagcc actcaaggta gaaaatgaag agcatggggc cccagaactg
     1261 tggtgccatc cagcttgccg ggtgggacag tgtgtggtgg tcttcagcca ggctcctagt
     1321 gggagagccc cactcagccc cagtttgaac tctcgcccat cacctatcag tgccactcct
     1381 ccagctctcg ttcctgaaac ccgagagtac cgctctcagt ctccagtaag aagcatggat
     1441 gaagctcctt gtgttaacgg ccgctgggga acactgagac ccagggctca aaggcagact
     1501 ccttcaggtt cccgggaagg gagcctttcc ccagccagag gagacggctc tcctatcctc
     1561 aatggtggga gtttgtctcc aggaacggca gctgtgggtg gctcttcttt ggacagtcct
     1621 gtacaggcca tatctccaag tactccatct gctcctgaag gatacgacct gaaaatagga
     1681 ctttctttgg ccccccgacg aggatcacta ccagatcaga aagatctgag attaggatcc
     1741 atagatctga attgggatct gaaacccgct tccagtagta atcccatgga tggcatggac
     1801 aataggacag ttgggggaag tatgagacac cctcctgaac agacaaatgg tgtgcatacc
     1861 ccacctcacg tggccagtgc ccttgcaggg gccgtctccc caggtgccct gcgtcggagt
     1921 ctggaagcca tcaaagcgat gtcctccaaa ggcccctcgg cctctgcagc actaagtcct
     1981 cctcttgggt cttctccagg ctctcctggg agccagagtt tgagcagtgg agaaacagtg
     2041 cccatccctc gcccagggcc tgcccaagga gatggacatt ccttacctcc cattgctcgc
     2101 cgcctgggcc accaccctcc acagtcccta aatgttggca aacccctata ccagagtatg
     2161 aactgcaagc ccatgcagat gtacgtgctg gacattaaag acaccaagga gaaggggcgg
     2221 gtcaaatgga aagtatttaa tagcagttct gtggttggac ctcctgaaac cagcctgcat
     2281 accgtggtac aaggcagggg tgaactcatc atatttggag gactcatgga caagaaacag
     2341 aatgtgaagt actatccaaa aacaaacgcc ttgtactttg tacgagcaaa gagataatgt
     2401 gttctaaacc cctttccttt tctgtggctt ttaatttgga attttccagt gtgtaagcat
     2461 ttggactgag aattgggaaa acaaaattac tcccagaagc caaaactctt taattcccaa
     2521 ccgaagtcac tccaggctgg gatcaaatct ccattaagaa aaaaaattat atataaatat
     2581 atatatatat attatatagc caactctgtt gacaaaaaaa gggagagatt tccatcctgg
     2641 ttcagataaa gttgttgctg tgttttaaca ggggctgggc tgcctttttc taccttgctg
     2701 gtaactagac caagaagtta gagaatagac taacatcagt aacttcccaa aagaaactga
     2761 agagccccct gtaaatcttt atgtggcctt cttggagtta aaaaatgaaa gggcatatgt
     2821 aagttgcaaa ggtggagggt tttagactct catgcttcag gtgctgtcgg ggtaaaagta
     2881 actgtttttc cccttctctt aaaaccacag aggacctgtg acagctctgc agaaatgcca
     2941 gtgcctggcc ccctcttgcc ttttatggct gaggaaagtt acccaacaaa ggattttatt
     3001 ccacatttgt gtgccgggtc attgtgaaat aatgtttatg cagccaacat ctgaccgcct
     3061 agtagtgtcc attggtcttt ggagtgcttc ttgtgtgtct cagaaaacat tttgtgtctg
     3121 attgtggaaa tttctgacaa tcaatcatat ttggtggcaa gttgccaaaa aacatattta
     3181 ttctcctctt tcttccctta gaacatggta cttggaaact gccttttcca ttcacttaca
     3241 ggctgctttt ttcttctacc ttttttcttt tctttttttt ttttcatatg tggtgaagtc
     3301 ctaaaacctg tctgactttc tgtttctttt acaaagctca ggtgcctaca gaaatcagaa
     3361 gctgcttaga aatacttgtg gaaccctttc cctggtgtca ctagggggcc agtagggaat
     3421 tctaagatgc caatattgtg agaaatcttt gaagcaagca tcaaaagata ctgttttttc
     3481 cctatgggct tctttttact tccaaagcac attgagcaca ctcatcccat atttgtagaa
     3541 tgtggaaatt gattctggaa gggaattcca ataacagttc tttttagaaa tgtttttttc
     3601 cttgtggtga catatattcc tcttcctggc tattggcagg tgatggagtt gagaatcatg
     3661 tacttgactt cttgacgcat ggctgacctc agaaacagct ccatcctttg cacttgtctt
     3721 cttcatgtgt cacccaaata gggcttgggt ttttactttc acttcatttc tgagattaag
     3781 gtgtaaccaa gtagagcatt tctttgcttg atacagaaag ttactagtct caaccatggc
     3841 ctgggcatag gagatgtcaa aataagttta tttcaaatgg caccatttaa atagggattt
     3901 ttggtgattt ctcatcagtg gaaagaggat ttttgttttg cctttgtttt gttttgaaat
     3961 ttaaatccta atttcaaaac atcaccttgc caccctgaca ctcctctttt tattattagc
     4021 gtttctcagg cacaaagcct gctgcagctg gccctgggtc ctggctttca gccagcatct
     4081 ggcagcctaa gtgtactgat aagtgtgttt tctcctgtta catcatgctg aatcctttcc
     4141 cttagccatt agcttttatg atgtggtctt cgtaggaaag ccaccctggt gccaagccta
     4201 gcttgtgggg aggggtatgt gttccagaaa ctgctctttg tgttcccttc aatgaggaaa
     4261 caacatgtgt ctacttatgt ggcatccaac tgcttggagc tccacacttc cctttcgcga
     4321 ctcaggctct ggtgctgttg ccaatccttg cttggcaaag actgttcgat catgtggggt
     4381 ccttatttac aagggaaagc tgggccagaa ggctagcaat tcaggtgtta ccgctattgc
     4441 tgtaccttgt gttaggacat tgtgtttgtg catggactgt gcctccaaac tcagtagttc
     4501 ctatctaaat ataaagtata ttagaaacct gaaagtacag aatctcaacc ttacagtctt
     4561 tcccttagtc ctgtggcctt cctaagccag ctgttaacgt gttgattcct tccacttccc
     4621 ccaagtaggc aggcaacaga tatgttgatt gtcttagaaa gtaatctggt tcctctgaac
     4681 tccattgaat tccagtttga cgcatactgc ctggaaccag actgtttgct tacagctttt
     4741 taagaaaaat ctgccttgtc tgcccccatt atggttggtc ttggtagctc ctgggcactg
     4801 tgggcgtgta ccatgggaaa gtgattcaac acagtgaagg tgattgtctc ctcaggcctc
     4861 ctgaagccac ctgtgcggtg ggacttcacg tgtctcggcc aaggcgagca tttccacaat
     4921 gccgtggatg ctgcagtcag gccagattga accatgaccc catttttcac atgataccaa
     4981 ttttgtctta aaattcactg agaaaaatga gactaaattt tttttaaccc tcaggagcac
     5041 ctgaagcaaa tatttatccg tatttattga aaattcattt tgtttctact tgaagcttta
     5101 accccttcca ttcctgcaag tgtgcctttt gagagctccc atggcctagt gacttcactg
     5161 gtcaccttgt ccatcttact taagaatttt agtctctccc taccctcttg gacagagctt
     5221 cctgttctct tatttcacag gttatacagc agagcgggtt ttgtgttttc attcctattt
     5281 ccacccttca tttggttggt ggactccaca acctcaccct accctacact ttgggagcac
     5341 aaatttggtg ttgaaacaag cttaaatttc attttagggc atactgggct tactctcctc
     5401 ccagctgtct gtggattgat ttgattttaa tgttcgagtt ttacagcaac agctgaaaac
     5461 catgaactat tctaggaact gtgttggaac tctttaaaat aaagaaaaga ggaggaggag
     5521 gaggaagaaa gaaaaccaac ttaagaagcc ttgactttgg aggacagaaa gccaccagcc
     5581 aatggagaac aaagagatgt ttccctttcc tttctttcac cttgtcattc tgggtttcct
     5641 tctgcttcac tctttccttc ccccttaaaa gtggtattcc tggttggtct gtctgtctgt
     5701 ccttgtcctt gtggtgatcc tggcatggtg atatgctcca ctttgcatta tccatggtct
     5761 cttaccagcg cacaagtcag tggggaggat ctaaccacgc ctggtggtga ggaagctgaa
     5821 tttccaggcc tgcgtcccat gtagcctctc catgaactgc agaaggcatg ttctgcatgg
     5881 ttaccagtaa gtggctccct ctcaccgtgt tcattgtcaa atgagagcaa actttaggtg
     5941 ttggctccat tgtacactct acttgctctg ctcccctccc tccaaccagg gttcatgtca
     6001 gtgcacaccc catgtgccct ggcgaagctg gtgctgtgag tgatgtttcc catacaactc
     6061 agggatgcca ggtggcttac cctgagatag tcattttggg cacataacag tgtaggaatg
     6121 aaacatggat ttcattgata tttaaatctg tcaatttcat tttttgttaa tgttttcccc
     6181 tgatgacttt ttagcaattt aacaaataaa atggacaatt gtcttaa
//
