LOCUS       NM_001371389            7377 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens F-box protein 41 (FBXO41), transcript variant 2, mRNA.
ACCESSION   NM_001371389 XM_011532562
VERSION     NM_001371389.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7377)
  AUTHORS   Agrawal,Y., Sharma,T., Islam,S., Nadkarni,K.S. and Santra,M.K.
  TITLE     F-box protein FBXO41 suppresses breast cancer growth by inducing
            autophagic cell death through facilitating proteasomal degradation
            of oncogene SKP2
  JOURNAL   Int J Biochem Cell Biol 147, 106228 (2022)
   PUBMED   35598880
  REMARK    GeneRIF: F-box protein FBXO41 suppresses breast cancer growth by
            inducing autophagic cell death through facilitating proteasomal
            degradation of oncogene SKP2.
REFERENCE   2  (bases 1 to 7377)
  AUTHORS   Agrawal,Y., Nadkarni,K.S., Gupta,N.A., Manne,R.K. and Santra,M.K.
  TITLE     F-box protein FBXO41 plays vital role in arsenic trioxide-mediated
            autophagic death of cancer cells
  JOURNAL   Toxicol Appl Pharmacol 441, 115973 (2022)
   PUBMED   35278439
  REMARK    GeneRIF: F-box protein FBXO41 plays vital role in arsenic
            trioxide-mediated autophagic death of cancer cells.
REFERENCE   3  (bases 1 to 7377)
  AUTHORS   Mukherjee,C., Holubowska,A., Schwedhelm-Domeyer,N., Mitkovski,M.,
            Lee,S.J., Kannan,M., Matz,A., Vadhvani,M. and Stegmuller,J.
  TITLE     Loss of the neuron-specific F-box protein FBXO41 models an
            ataxia-like phenotype in mice with neuronal migration defects and
            degeneration in the cerebellum
  JOURNAL   J Neurosci 35 (23), 8701-8717 (2015)
   PUBMED   26063905
  REMARK    GeneRIF: This study show that FBXO41 is a critical factor, not only
            for neuronal migration in the cerebellum, but also for its
            long-term integrity.
REFERENCE   4  (bases 1 to 7377)
  AUTHORS   Liang,H., Song,Z., Lei,J., Tang,J., Xu,H., Deng,X., Qi,Y., Zheng,W.
            and Deng,H.
  TITLE     Genetic analysis of the F-box only protein 41 gene in Chinese Han
            patients with Parkinson's disease
  JOURNAL   Parkinsonism Relat Disord 19 (10), 918-920 (2013)
   PUBMED   23777664
  REMARK    GeneRIF: Our finding suggests that the FBXO41gene may be a non-X
            chromosome-related Parkinson disease risk factor
REFERENCE   5  (bases 1 to 7377)
  AUTHORS   Ebstein,F., Lange,N., Urban,S., Seifert,U., Kruger,E. and
            Kloetzel,P.M.
  TITLE     Maturation of human dendritic cells is accompanied by functional
            remodelling of the ubiquitin-proteasome system
  JOURNAL   Int J Biochem Cell Biol 41 (5), 1205-1215 (2009)
   PUBMED   19028597
REFERENCE   6  (bases 1 to 7377)
  AUTHORS   Jin,J., Cardozo,T., Lovering,R.C., Elledge,S.J., Pagano,M. and
            Harper,J.W.
  TITLE     Systematic analysis and nomenclature of mammalian F-box proteins
  JOURNAL   Genes Dev 18 (21), 2573-2580 (2004)
   PUBMED   15520277
REFERENCE   7  (bases 1 to 7377)
  AUTHORS   Watanabe,N., Arai,H., Nishihara,Y., Taniguchi,M., Watanabe,N.,
            Hunter,T. and Osada,H.
  TITLE     M-phase kinases induce phospho-dependent ubiquitination of somatic
            Wee1 by SCFbeta-TrCP
  JOURNAL   Proc Natl Acad Sci U S A 101 (13), 4419-4424 (2004)
   PUBMED   15070733
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC010913.9.
            This sequence is a reference standard in the RefSeqGene project.
            
            On May 20, 2020 this sequence version replaced NM_001371389.1.
            
            Summary: This gene encodes a member of the F-box protein family,
            which is characterized by an approximately 40 amino acid motif, the
            F-box. F-box proteins constitute one of the four subunits of the
            SCF ubiquitin protein ligase complex that plays a role in
            phosphorylation-dependent ubiquitination. F-box proteins are
            divided into three classes depending on the interaction substrate
            domain each contains in addition to the F-box motif: FBXW proteins
            contain WD-40 domains, FBXL proteins contain leucine-rich repeats,
            and FBXO proteins contain either different protein-protein
            interaction modules or no recognizable motifs. The protein encoded
            by this gene belongs to the FBXO class. [provided by RefSeq, Feb
            2014].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR4352444.491161.1,
                                           ERR3218374.617908.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000520530.3/ ENSP00000430968.2
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-319               AC010913.9         196432-196750       c
            320-1362            AC010913.9         180998-182040       c
            1363-1588           AC010913.9         178729-178954       c
            1589-1662           AC010913.9         178165-178238       c
            1663-2021           AC010913.9         177554-177912       c
            2022-2263           AC010913.9         176550-176791       c
            2264-2379           AC010913.9         176210-176325       c
            2380-2532           AC010913.9         175950-176102       c
            2533-2628           AC010913.9         175485-175580       c
            2629-2747           AC010913.9         173012-173130       c
            2748-2906           AC010913.9         172661-172819       c
            2907-3022           AC010913.9         171453-171568       c
            3023-7377           AC010913.9         166962-171316       c
FEATURES             Location/Qualifiers
     source          1..7377
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p13.2"
     gene            1..7377
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /note="F-box protein 41"
                     /db_xref="GeneID:150726"
                     /db_xref="HGNC:HGNC:29409"
                     /db_xref="MIM:609108"
     exon            1..319
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /inference="alignment:Splign:2.1.0"
     exon            320..1362
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /inference="alignment:Splign:2.1.0"
     CDS             458..3085
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /codon_start=1
                     /product="F-box only protein 41"
                     /protein_id="NP_001358318.1"
                     /db_xref="CCDS:CCDS46337.2"
                     /db_xref="GeneID:150726"
                     /db_xref="HGNC:HGNC:29409"
                     /db_xref="MIM:609108"
                     /translation="MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYSHTYETLYILSKT
                     NSICDGAAAAAAAAAAASGFPLAPEPAALLAVPGARREVFESTSFQGKEQAAGPSPAA
                     PHLLHHHHHHAPLAHFPGDLVPASLPCEELAEPGLVPAAAARYALREIEIPLGELFAR
                     KSVASSACSTPPPGPGPGPCPGPASASPASPSPADVAYEEGLARLKIRALEKLEVDRR
                     LERLSEEVEQKIAGQVGRLQAELERKAAELETARQESARLGREKEELEERASELSRQV
                     DVSVELLASLKQDLVHKEQELSRKQQEVVQIDQFLKETAAREASAKLRLQQFIEELLE
                     RADRAERQLQVISSSCGSTPSASLGRGGGGGGAGPNARGPGRMREHHVGPAVPNTYAV
                     SRHGSSPSTGASSRVPAASQSSGCYDSDSLELPRPEEGAPEDSGPGGLGTRAQAANGG
                     SERSQPPRSSGLRRQAIQNWQRRPRRHSTEGEEGDVSDVGSRTTESEAEGPLDAPRPG
                     PAMAGPLSSCRLSARPEGGSGRGRRAERVSPSRSNEVISPEILKMRAALFCIFTYLDT
                     RTLLHAAEVCRDWRFVARHPAVWTRVLLENARVCSKFLAMLAQWCTQAHSLTLQNLKP
                     RQRGKKESKEEYARSTRGCLEAGLESLLKAAGGNLLILRISHCPNILTDRSLWLASCY
                     CRALQAVTYRSATDPVGHEVIWALGAGCREIVSLQVAPLHPCQQPTRFSNRCLQMIGR
                     CWPHLRALGVGGAGCGVQGLASLARNCMRLQVLELDHVSEITQEVAAEVCREGLKGLE
                     MLVLTATPVTPKALLHFNSICRNLKSIVVQIGIADYFKEPSSPEAQKLFEDMVTKLQA
                     LRRRPGFSKILHIKVEGGC"
     exon            1363..1588
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /inference="alignment:Splign:2.1.0"
     exon            1589..1662
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /inference="alignment:Splign:2.1.0"
     exon            1663..2021
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /inference="alignment:Splign:2.1.0"
     exon            2022..2263
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /inference="alignment:Splign:2.1.0"
     exon            2264..2379
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /inference="alignment:Splign:2.1.0"
     exon            2380..2532
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /inference="alignment:Splign:2.1.0"
     exon            2533..2628
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /inference="alignment:Splign:2.1.0"
     exon            2629..2747
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /inference="alignment:Splign:2.1.0"
     exon            2748..2906
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /inference="alignment:Splign:2.1.0"
     exon            2907..3022
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /inference="alignment:Splign:2.1.0"
     exon            3023..7377
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7353..7358
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /note="hexamer: AATAAA"
     polyA_site      7377
                     /gene="FBXO41"
                     /gene_synonym="FBX41"
                     /note="major polyA site"
ORIGIN      
        1 acctcggtgc tgcctccctc ccccttccct tgctttcctc ggcccgcgcg ccccctcctc
       61 cccctcctcc tcctcctcct cctccatcct tcctcccgcc gggttcgtgc gcccctcccg
      121 ctgcgactgg ctgggaggtt cggccgcccc cgccccgaga gggaggcggg ggcgctagcc
      181 gcggcggcca cccaaggctg cggaggggaa cgagatccga ggccccaagg cggccctgcg
      241 tctggaccgg gcacgcgggg gctcttctgc gtccccagcc ctgggccgct gggcctggcc
      301 tcgccgcggg gtggaggagc ctcctcgccc caggccgcgg gcgccctgag ccttcctgac
      361 cccgcagggg gcctcgcccg cggtccccca tgagcgcgcc cggctgaccg gcggggcggc
      421 cgcggtggag cccgcgtgcc gcgggggcgg cggggccatg gcctcgctgg acctgccgta
      481 ccgctgcccc cgctgcgggg agcacaagcg cttccggagc ctgtcgtcgc tgcgcgcgca
      541 cctggagtac agccacacct acgagacgct ctacatcctc tccaagacca acagcatctg
      601 cgacggcgcc gccgccgccg cggccgccgc cgccgctgcc tcggggttcc cgctggctcc
      661 cgagcccgcc gccctgctgg ccgtgcccgg cgcccggcga gaggtcttcg agagcacttc
      721 cttccagggc aaggagcagg cggccgggcc gtcgcccgcg gcgccgcacc tgctgcacca
      781 ccaccatcac cacgctcccc tcgcccactt ccccggcgac ctggtgcccg ctagcctgcc
      841 ctgtgaggag ttggccgagc cgggccttgt gcccgccgca gcagcgcgct atgcgctgcg
      901 cgagatcgag atcccgctgg gggagctgtt cgcccgcaag tccgtggcgt cctcggcgtg
      961 ctcgacgccg ccgcctggcc ccggccccgg cccttgcccc gggcctgcct ccgcttcgcc
     1021 cgcgtccccc tcacccgctg atgtggccta cgaagagggc ctggcgcgcc tcaagatccg
     1081 cgcgctggag aagctggagg tggaccggcg gctggagcgg ctgagcgagg aggtggagca
     1141 gaagatcgcg ggccaggtgg gccggctgca ggccgagctg gagcgcaagg cggccgaact
     1201 ggagactgcg cggcaggaga gtgcgaggct cgggcgcgag aaggaggagc tggaggagcg
     1261 cgcgtctgag ctctcccgcc aggtggacgt gagcgtagag ctgctggcct cactcaagca
     1321 ggacctggtg cacaaggaac aggagctgag ccgcaagcag caggaggtgg tgcagatcga
     1381 ccagttcctg aaggagacgg cggcgcggga ggccagcgcc aagctgcggc tgcagcagtt
     1441 cattgaggag ctccttgagc gggctgaccg tgccgagcgg cagctgcagg tcatcagcag
     1501 cagctgtggc agcacgccca gcgccagcct gggccgtgga ggtgggggcg gtggtgctgg
     1561 acccaatgcc cggggcccag gcagaatgcg agaacaccac gtgggcccgg ccgtgcctaa
     1621 cacatatgca gtgtcacggc atggctcctc tccgagcaca ggggcctcca gccgtgtgcc
     1681 agccgcatcc cagagctcag gctgctatga cagtgacagt ctggagctgc ccaggccaga
     1741 ggagggggcc cctgaggaca gtggccctgg gggcttgggc acacgggccc aggctgccaa
     1801 cgggggctca gagcggtccc agccccctcg cagctcaggc ctgcggcgcc aggccatcca
     1861 gaactggcag cgcagacccc gccgacacag cactgagggg gaagagggtg atgtctccga
     1921 cgttggctcc cgaaccactg agtcagaggc tgagggcccg ttggatgcgc cccgccccgg
     1981 gcctgctatg gctgggccat tgagcagctg ccggctctca gcccgccccg agggaggcag
     2041 tgggcggggt cggcgagcag agagggtcag cccctcacgc tccaatgagg tcatcagccc
     2101 agagatcctg aagatgcgag ctgccctctt ctgcatcttc acctacctgg acacgcgcac
     2161 actgctgcat gctgccgagg tctgccggga ctggcgcttc gtggcccgcc accccgcagt
     2221 ctggacaagg gtgctgcttg agaatgcccg tgtctgctcc aagttcctgg caatgctggc
     2281 tcagtggtgc acccaggccc actctctgac gctgcagaac ttgaagcccc ggcagcgggg
     2341 aaagaaggag agcaaggagg agtatgcccg gagcacccgg ggctgcctgg aagctgggct
     2401 ggagtccctg ctgaaggcag ctggggggaa cctgctgatc ctgcgcatct cccactgtcc
     2461 aaacatcctc accgaccgct cgctctggct ggccagctgc tactgccgtg ccctgcaggc
     2521 tgtcacgtac aggagtgcca cagaccccgt gggccatgag gtcatttggg ccctgggcgc
     2581 aggctgcaga gagatcgtct ccctccaagt ggcaccactt cacccctgcc agcagcccac
     2641 acgcttcagt aaccgctgcc tgcagatgat tggtcgctgt tggccccacc tgcgggccct
     2701 gggggtcggg ggtgccggct gtggggtgca gggcctggca tcactcgcga gaaactgcat
     2761 gcggctgcag gtcctggagc ttgaccacgt gtcagagatc acccaggagg tggcagcaga
     2821 ggtctgccgg gaaggcctga agggactgga gatgctggtg ctcacggcga ctcccgtcac
     2881 ccctaaggcc ctactgcact tcaacagcat ctgccggaac ctcaagtcca ttgtggtcca
     2941 gattgggatt gcggattatt tcaaagagcc cagcagccct gaggcccaga agctgtttga
     3001 ggacatggtg acaaaactcc aggctctgcg acggaggccc ggcttctcta agattctgca
     3061 catcaaggtg gaaggcggct gctaacccgg gtagggggcg gcagggcccc tgccagcccc
     3121 acaccagggc actctctttg gacctcagag ggaccctggt ttggactaga cctttggagg
     3181 ccgagtgtta tccctggctt ctggaggggg actgtcaagt ctcctgtcct cctcctggag
     3241 cagcagagca acaggcctga cccagggcac tgcctcccca gtacaggggc ttggacagaa
     3301 gctgccctcc gacccccacc ctaccccggc tggagtagcc tctggcacag ccagtgagga
     3361 gctgtcacca ccagcgcctg gtgtcatcac ctggaggatc tgcaataacc acccagtggc
     3421 tcctcagctg ttctggctgg cctctccttc ctgaggccca gcctcctggt caggagcatc
     3481 tggggcccca agccaatggg ggctccacaa ggcagctcag acttggcaag gagggctctt
     3541 ctcctcaacc ttgctgcagc cttctggggg caccccttca gacagcctgc ccaggctgtg
     3601 gatccacatt tcctgggggt accacagcca gacctagggg cctgggcacg tggtcagcca
     3661 aaagctgggg gcagcagtac agtggggtag tgggggtggg tttggaaagg aaacagtcac
     3721 ccagaacttc tccccaggat gagaccaccc ttccaaggtg ggggattgcc agggggagaa
     3781 aacttattta ttgctgtaag acaggacccc tcctcccaac ctcatacccc accgcacacc
     3841 agagctaaat tcaaagctga aaggcgcacg tttctatacc tacattcatt cctgagggac
     3901 cctccagagg gtcaaggtcc cagccccagg cagccctgtc acagtgagaa gtagttcctg
     3961 tccttaagga atttccttct aatccaggtg cttgggcagg aacccgatgg ccttcgggtc
     4021 accaaggctg tctgggaggg aggcacaggg ccgccctctg tgctgaggcc gtggaggaag
     4081 ccaggaggag ggtggcttgc tttgcttcct tgtctaatta gcttgcttga agatgtggcc
     4141 ttggcaggga gccagaccca tggggccaag gaagaggaag agcatcctca atagactcac
     4201 tcccccttcc ttggtctcca cgggccccgt ggactgaggg ctgcattggg gtcttctgcc
     4261 taggggaagt gctggacctg agctggagcc acttggctta gaagccacag gattcacttt
     4321 tcactggcct ttgcagtccc caaaggatca ggtctcagaa ccaaggctcc aaaggctgag
     4381 gtctccccag ttcctcctct cagaactccc acagtagctc agaggccggg ggtcctgcca
     4441 actttcattt ggaaagttct ttcgaacatc taaactagat ctatcttagg gtttctttct
     4501 ctcctagata ggatcagctc ccagccctag ccattaggct gctggtcctg gcgggggatg
     4561 gggtcccctc gttacccagt ccttcccagg gacccaactt cctaacacaa cctggcttgg
     4621 acatgaagac cctcccccag gttaccttgt aaagagtcct ccagagctgg gatcccatgg
     4681 gcgcagcagc acacccagct cccatggcgt cactccctag ctctgtccca gcttttgcta
     4741 tcattgctga cttttcctcc tgtggctcat tctgtccctg ccctttgaaa acctaaaata
     4801 ccaagggtgt catgctggca actccctgcc cagtcctgca caaagccttg gctgtgtgtg
     4861 gcaccccttg cctcctaccc cagagcagct ggctccattg gcttctccct gcaccagccc
     4921 tgtcctcagg ggtcaggaaa aagcagcaca gctttctttc ctctcctcca gaggcctgga
     4981 agggaggtgg aggtccagta agggcctggc tgccttggat ttcttggtcc tgccttgcca
     5041 actgcaccct gtagctcctg ctccctgtga ccccagaacc agaggtgctg ccttccctgt
     5101 ctcctagaca aagcacaaag ggatgccctg cttggcttga gcctgcccaa ctgaaggatt
     5161 ttctctgccc cagggacctt ccatccctga atacaaggct ctaggcaact tctctctggg
     5221 tggtacacac tagaatgcct ggcattagcc ctagaaagga ggttggggtg tatgggtagt
     5281 gagctagggt gggagaaagg tggtgctgaa aggacagatg ctagttgtag tttcactcac
     5341 tcattcattc attagtgcaa cagtactgag caccacctgc actagaggca gaggggtgaa
     5401 caagataccc ttctgcctgg ggggacgtcc acttcccatg ggtttggcta tttccaggaa
     5461 agcccctcag tcctccaccc tgttctggct gtgtgtgaag gatgtgtgtg agcaggccca
     5521 atcctttgca gcaagaatga gaggtcagag tattccattg cacacgcacc ctggggctga
     5581 cagacttgtg ccccctagcc ttcatgcatg cccaagcact ggcagctttg cagcccctgc
     5641 cccaccagcc ccttgacgct cttcttttgt tctctcctcg gggatgagct ctgctgctga
     5701 gtagggagct tttgcttgct gggaggctct atgcatggat ttttttggtg accatacagc
     5761 tagggctgag gatgggaaca gggacagagg gcctggctat ccctagaagc acttcatcca
     5821 tctttaccca cccaaacggg atcccttcac atctcatacc cagtaagatg caagaaagga
     5881 atatctgaga gcaagcagcc ctgctccagg ggccccaggt atgtgtagag gcccagtggg
     5941 ggtggccact tggtgtttct accaccccct gccatccagt ctggccccag tacctacctg
     6001 ggaggttggt gtacttggct taagtacttc atgctttatt caggctgctt ccccacagca
     6061 ccggcaggaa atgaaggtgc acttatatgc atccctgcag gaataaagag tgggtggcct
     6121 gcccagccca gcaccacagc ctttccccag ccaggagaga ccacctaagg atcaaggcag
     6181 ctcctgtttt cttggttctg tgacactcga gtctgagcca gcccctcagg aattgcctca
     6241 aaagagaaaa acaaaaaaaa gtcctccttc ccaaggcctg ctactccaag gtttggctcc
     6301 atcccttgcc tttgggtcct gcctatttcc ccactcctgg tctcttatct ttggggccac
     6361 cagtggggag tcacccgggc cccaatccct ctaaggcgct aagttgaagg aggccttccc
     6421 agagtgacta ttggtgccaa agtcccagtt cctgttggac ttggggtaaa aacaggagat
     6481 ggtgagtggg tgtaaggccc aaatgcccag agaagttaac tcgaacccat gggacctgtc
     6541 ccagcctgtc agtccctgat gagtgtaact tccttcccct gggggcctgg cccttctctc
     6601 caacccagtg gccatgcttt ctcacccagc cttgtgcccg gcctgcattt ctgtatatat
     6661 tgctgtgtat tgtgtgtatg tatgtattcc tggacaagtg tgttcatctg cagcccttgc
     6721 ctgaggataa ggtttaggat tgggtaaaga tcagaatacc agggccagct aaggcaacga
     6781 ctccctcccc aaacccttgg gacctcagcc agtcccaagg ctgccctgac aatcaggcag
     6841 gctccccacc gtgaggccaa gcctcctctg ccactgccag catggcccaa gggaggcttg
     6901 gccttgggct tgccagcctc agctctgccc tgacaagggt cttgtatcca gggcagaggc
     6961 ctgaggtgac ccaggcttgc tttgtggctg atgccagcag gcttggttct agtgggcacc
     7021 actggtgggc aacctccata actggccctt aggccctacc ttcctacaca gctaggctat
     7081 aatgggcctg agtgagaggg tagcttcccc agccccaagc acaggcagag gggtggagag
     7141 caatttttgg ttttattttt gtttctgaag tggtgcctgt acctccagcc cccagggggc
     7201 cttccctggc cacacttctc tgccccaccc aggcatcgcc atcccagcac tttgctccat
     7261 gtcacccgta agatgccctt tgctgaatgt acctgagtgt atgtatttaa aaggactcac
     7321 atgggcatca gagaatttat ggctctgtat ccaataaaaa agatggtgaa actggtc
//
