LOCUS       NM_001319193            4874 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens Fas binding factor 1 (FBF1), mRNA.
ACCESSION   NM_001319193
VERSION     NM_001319193.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4874)
  AUTHORS   Zhang,Y., Hao,J., Tarrago,M.G., Warner,G.M., Giorgadze,N., Wei,Q.,
            Huang,Y., He,K., Chen,C., Peclat,T.R., White,T.A., Ling,K.,
            Tchkonia,T., Kirkland,J.L., Chini,E.N. and Hu,J.
  TITLE     FBF1 deficiency promotes beiging and healthy expansion of white
            adipose tissue
  JOURNAL   Cell Rep 36 (5), 109481 (2021)
   PUBMED   34348145
  REMARK    GeneRIF: FBF1 deficiency promotes beiging and healthy expansion of
            white adipose tissue.
REFERENCE   2  (bases 1 to 4874)
  AUTHORS   Inoko,A., Yano,T., Miyamoto,T., Matsuura,S., Kiyono,T., Goshima,N.,
            Inagaki,M. and Hayashi,Y.
  TITLE     Albatross/FBF1 contributes to both centriole duplication and
            centrosome separation
  JOURNAL   Genes Cells 23 (12), 1023-1042 (2018)
   PUBMED   30318703
  REMARK    GeneRIF: Albatross is a novel protein that spatiotemporally
            integrates different aspects of centrosome function, namely
            ciliogenesis, centriole duplication, and centrosome separation.
REFERENCE   3  (bases 1 to 4874)
  AUTHORS   Huang,W.Q., Ye,H.M., Li,F.F., Yi,K.H., Zhang,Y., Cai,L.L.,
            Lin,H.N., Lin,Q. and Tzeng,C.M.
  TITLE     Analysis of genetic polymorphisms associated with leukoaraiosis in
            the southern Chinese population: A case-control study
  JOURNAL   Medicine (Baltimore) 95 (35), e3857 (2016)
   PUBMED   27583843
  REMARK    GeneRIF: These results suggest that rs1135889 in FBF1 is not
            associated with leukoaraiosis (LA) risk in the Chinese population.
            However, the association of rs1135889 (FBF1) with LA before
            Bonferroni correction and Sidak correction is worth highlighting.
REFERENCE   4  (bases 1 to 4874)
  AUTHORS   Tanos,B.E., Yang,H.J., Soni,R., Wang,W.J., Macaluso,F.P.,
            Asara,J.M. and Tsou,M.F.
  TITLE     Centriole distal appendages promote membrane docking, leading to
            cilia initiation
  JOURNAL   Genes Dev 27 (2), 163-168 (2013)
   PUBMED   23348840
REFERENCE   5  (bases 1 to 4874)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   6  (bases 1 to 4874)
  AUTHORS   Sugimoto,M., Inoko,A., Shiromizu,T., Nakayama,M., Zou,P.,
            Yonemura,S., Hayashi,Y., Izawa,I., Sasoh,M., Uji,Y., Kaibuchi,K.,
            Kiyono,T. and Inagaki,M.
  TITLE     The keratin-binding protein Albatross regulates polarization of
            epithelial cells
  JOURNAL   J Cell Biol 183 (1), 19-28 (2008)
   PUBMED   18838552
  REMARK    GeneRIF: Keratins and the keratin-binding protein Albatross are
            important for epithelial cell polarization.
REFERENCE   7  (bases 1 to 4874)
  AUTHORS   Schmidt,T., Karsunky,H., Frass,B., Baum,W., Denzel,A. and Moroy,T.
  TITLE     A novel protein (Fbf-1) that binds to CD95/APO-1/FAS and shows
            sequence similarity to trichohyalin and plectin
  JOURNAL   Biochim Biophys Acta 1493 (1-2), 249-254 (2000)
   PUBMED   10978533
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC087289.9.
            
            On Apr 21, 2021 this sequence version replaced NM_001319193.1.
            
            CCDS Note: The coding region has been updated to represent an
            alternative splicing pattern that is more supported by the
            available transcript data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038193.1642665.1,
                                           SRR14038195.2543215.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000636174.2/ ENSP00000490726.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-195               AC087289.9         12345-12539
            196-281             AC087289.9         15155-15240
            282-309             AC087289.9         15794-15821
            310-351             AC087289.9         17714-17755
            352-445             AC087289.9         20299-20392
            446-506             AC087289.9         22098-22158
            507-557             AC087289.9         23340-23390
            558-675             AC087289.9         25194-25311
            676-753             AC087289.9         25855-25932
            754-873             AC087289.9         26510-26629
            874-1012            AC087289.9         26961-27099
            1013-1146           AC087289.9         27224-27357
            1147-1246           AC087289.9         27941-28040
            1247-1702           AC087289.9         29746-30201
            1703-1804           AC087289.9         31341-31442
            1805-1893           AC087289.9         31827-31915
            1894-1952           AC087289.9         32085-32143
            1953-2108           AC087289.9         32958-33113
            2109-2209           AC087289.9         33280-33380
            2210-2416           AC087289.9         33513-33719
            2417-2524           AC087289.9         35118-35225
            2525-2664           AC087289.9         35317-35456
            2665-2783           AC087289.9         35537-35655
            2784-2906           AC087289.9         38248-38370
            2907-3092           AC087289.9         38455-38640
            3093-3269           AC087289.9         39089-39265
            3270-3407           AC087289.9         39337-39474
            3408-3525           AC087289.9         39568-39685
            3526-3641           AC087289.9         41080-41195
            3642-4874           AC087289.9         42581-43813
FEATURES             Location/Qualifiers
     source          1..4874
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q25.1"
     gene            1..4874
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /note="Fas binding factor 1"
                     /db_xref="GeneID:85302"
                     /db_xref="HGNC:HGNC:24674"
                     /db_xref="MIM:616807"
     exon            1..195
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            196..281
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             279..3725
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /note="Fas binding protein 1; albatross; protein
                     albatross; Fas (TNFRSF6) binding factor 1"
                     /codon_start=1
                     /product="fas-binding factor 1"
                     /protein_id="NP_001306122.1"
                     /db_xref="CCDS:CCDS45779.2"
                     /db_xref="GeneID:85302"
                     /db_xref="HGNC:HGNC:24674"
                     /db_xref="MIM:616807"
                     /translation="MAPKTKKGCKGSIDDFLGDLLGDDMTLPEKPVKLASHTRDTTGV
                     SQMFPSSKARTKSLLGDDVFSTMAGLEEADAEVSGISEADPQALLQAMKDLDGMDADI
                     LGLKKSNSAPSKKAAKDPGKGELPNHPKPAGGAIPTKKSLPSPSSSGHQNRRFSSEDL
                     EDPLRGLLSYDEGGITKQPPVTQSKTASDKSPSTVRDQGPSIPLTPGDTPIRKKEELL
                     FDDGDDIMATLGFGDSPKAEKRQIGDQEGPRPARSTLDELLGRGMATKLLARPGTGEH
                     REFKLDKKYQRPQDSEDMWGDEDFTFGAYQPTVVSSEGRQSRRQSVSRFFADSGADPK
                     GEPGSKQSPPMASSPIQPRKGGADWLGLKDEDLDLFPASPTREAHRESSVPVTPSVPP
                     PASQHSTPAGLPPSRAKPPTEGAGSPAKASQASKLRASKEEKEDWLSHALSRKKSQGL
                     AREQHAGTSEGLHLAGTAGHPPSGSQPLTSTQGLEHAAAGGSSGTTARERPCVRPGVS
                     GSPVTQNHAASALPTGSPKRGTAPGDLSATEPATCFPSTQKPTEPSVPVQPLLPESLA
                     RSLLPSTEYQKQLLAAQVQLQCSPAELQAELLHSQARLAELEAQVRKLELERAQHELL
                     LGSLQQQHQADLELIESAHRSRIKVLETSYQQREERLRRENEELSARYLSQCQEAEQA
                     RAELTAQHQRRLAAIAQEKDQEMERLRELQRASILDMRRDHEEQLQRLKLLKDREVDA
                     ATSATSHTRSLNSIIHQMEKFSSSLHELSSRVEASHLTTSQERELGIRQRDEQLRALQ
                     ERLGQQQRDMEEERSRQQEVIGKMEARLNEQSRLLEQERWRVTAEQSKAESMQRALEE
                     QRKVTAQQMAMERAELERAKSALLEEQKSVMLKCGEERRRLAAEWAEFSAQQKLSKER
                     AEREAERALQVDTQREGTLISLAKEQAELKIRASELRAEEKQLAAERAALEQERQELR
                     LEKERINATALRVKLRAEEVESMSKVASEKYEEGERALREAQQVQAEQQARLQAVQQQ
                     QERLRKQEQHMHQEHLSLAQQRLQLDRARQDLPSSLVGLFPRAQGPAASSQSALMPPA
                     PTTRWCSQPPTGLDPSPLHLHARLALLRHMAEQDRDFLENEQFFLETLKKGSYNLTSH
                     SA"
     exon            282..309
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            310..351
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            352..445
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            446..506
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            507..557
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            558..675
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            676..753
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            754..873
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            874..1012
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1013..1146
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1147..1246
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1247..1702
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1703..1804
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1805..1893
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1894..1952
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1953..2108
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2109..2209
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2210..2416
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2417..2524
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2525..2664
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2665..2783
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2784..2906
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2907..3092
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3093..3269
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3270..3407
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3408..3525
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3526..3641
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3642..4874
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      4604
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /note="major polyA site"
     regulatory      4850..4855
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
                     /note="hexamer: ATTAAA"
     polyA_site      4874
                     /gene="FBF1"
                     /gene_synonym="Alb; FBF-1"
ORIGIN      
        1 agacggctga gggtgccggc agcggctgga agcgggaggc cagtcctggc cgggctgggc
       61 gacccgaatg gagccagggc cggcgctggt cccagcggcc gcacctccgg gggcacggcg
      121 cgtaacagga ggcttccggg gctgagagcg ttacaggctg cgctccgggg ccagataggc
      181 cgggcgctca gaaggggagt atgagcctga tgtgggcaga atccagatga gctggccagt
      241 gctgtgaagg agctgagagc acccccgaga gccgtgagat ggcaccaaaa accaagaaag
      301 gatgtaaagg ctccattgat gattttcttg gtgaccttct aggggatgat atgacactac
      361 ctgagaagcc tgttaaacta gcttcacata ccagagacac cacaggtgta tctcagatgt
      421 tcccttcttc aaaggcgaga acaaagtccc tcctgggtga tgatgtcttc agcaccatgg
      481 caggcctgga agaagctgat gctgaggttt caggtatctc agaggcagac ccacaggctc
      541 tgctccaggc catgaaggac ctggacggca tggatgctga tatcttaggt ctgaagaaat
      601 ctaattcagc ccctagcaaa aaagctgcaa aggaccctgg gaaaggagag ctgcccaacc
      661 accccaagcc tgcagggggt gccattccca ccaagaagtc acttccgtct cccagcagct
      721 ctgggcatca gaacaggagg ttttcctctg aagacttgga agacccattg agaggacttc
      781 tctcctatga tgaaggagga atcaccaagc agccgcctgt gacacagagt aaaacagctt
      841 ctgacaagag ccccagcaca gtgagagatc aaggtccctc tattcctcta actcctgggg
      901 acacccccat ccgaaaaaaa gaagaattgt tgtttgatga tggggatgac atcatggcca
      961 ccttggggtt tggagacagc cccaaagcag agaagaggca gataggagac caggaagggc
     1021 ctcgccctgc tcgctccacg ctggatgagc tgctgggtcg aggcatggcc accaaactcc
     1081 tggcccgccc gggcaccggg gagcacaggg agttcaagct agacaagaag taccagaggc
     1141 cacaggacag tgaagatatg tggggtgacg aggacttcac ctttggagcc tatcagccca
     1201 ctgtggtctc ctctgagggc cggcagtccc gccggcagtc tgtcagtagg ttcttcgcag
     1261 acagtggcgc agaccccaag ggagaaccag gctccaaaca gagccctcca atggcttcca
     1321 gccccatcca gcccaggaag ggaggagctg actggttggg cctcaaggac gaggacttgg
     1381 acctgttccc tgcctcaccc accagagagg cccatcggga aagttcagtg cctgtcacgc
     1441 cctcagtgcc tcctcctgcg agccagcact ccacgccagc tgggctgccc ccctccaggg
     1501 caaagccacc aactgaaggt gcagggtccc ctgccaaagc cagccaggct tccaagctgc
     1561 gagcctccaa ggaggagaaa gaggactggc tgagccatgc cctgtctcgg aagaagtccc
     1621 aaggcctggc cagagagcag catgctggga cctctgaggg cctgcatttg gcggggacag
     1681 cgggccatcc cccttctggc agccaacctc tcaccagcac acaagggctt gagcacgcag
     1741 ctgctggagg gagttctgga acaactgcac gagaaagacc gtgtgtcagg cctggtgtct
     1801 cggggtcccc tgtgactcag aaccatgccg cctcagcact ccctacaggt tccccaaaga
     1861 ggggaacagc ccctggagac ctctcagcca ctgagcctgc cacgtgtttc ccgagcaccc
     1921 agaaacccac agagccttcc gtgcccgtcc agcccctgct cccagagtcc ctggcccgga
     1981 gcctgctgcc gagcacagaa taccagaagc agctcctggc agcacaggtg caacttcagt
     2041 gcagccccgc tgagctccag gccgagctgc tgcatagcca ggcccggctg gcagagctgg
     2101 aggcccaggt gcggaagctg gagctagaac gggcccagca tgagctgctg ctggggagtc
     2161 tgcagcagca gcaccaggca gacctggagc tcatcgagag tgcacacaga agccgcatca
     2221 aggtgctaga aacatcgtac cagcaacggg aggagcggct ccggagagag aacgaagagc
     2281 tgtcagctcg gtatctgtcg cagtgccagg aggccgaaca ggcccgtgct gagcttacgg
     2341 cccagcacca gcggcgcttg gcggccatag cgcaggagaa ggaccaggaa atggagcggc
     2401 tccgggagct gcagcgggcg tccatcctag acatgcgcag agaccacgag gagcagctgc
     2461 agcggctaaa gctgctgaag gaccgagagg tcgatgcggc caccagtgcc acctcccaca
     2521 cgcggtccct gaatagcatc atccaccaga tggagaagtt ctccagcagc ctgcacgagt
     2581 tgtcctcccg cgtggaggcc tcgcacctca ccacctccca ggagcgggag ctggggatcc
     2641 ggcagcgtga cgagcagctg cgggcactgc aggagcggct gggccagcag cagcgggaca
     2701 tggaggagga gcggagccgg caacaggagg tcatcgggaa gatggaggca cggctgaatg
     2761 agcagagccg gctgctggag caggaacgct ggcgggtgac tgccgagcag tccaaggcgg
     2821 agtccatgca gcgcgcccta gaggagcaaa ggaaggtcac ggcccagcag atggccatgg
     2881 aaagggcgga gctggaacgg gccaagagcg ccttgctgga ggagcagaag tctgtcatgc
     2941 tcaagtgcgg ggaggagcgg cggcgcctgg ctgccgagtg ggcggagttc tccgcgcagc
     3001 aaaagctgag taaggagcgg gccgagcgcg aggccgagcg ggcattgcag gtggacaccc
     3061 agcgggaggg caccctcatc agcctggcca aggagcaggc tgagctgaag atcagggcca
     3121 gcgagctccg ggccgaggag aagcagctgg cagcggagag agcagccctg gagcaggagc
     3181 ggcaggagct gcggctggag aaggagagga tcaacgccac cgccctgcgt gtcaagctcc
     3241 gcgccgagga ggtggagagc atgagcaagg tggcctccga gaagtacgag gagggggagc
     3301 gggcattgcg cgaggcccag caggtgcagg cagagcagca ggcccggttg caggcggtgc
     3361 agcaacagca ggagcggctg cggaagcagg agcagcacat gcaccaggag catctgagtc
     3421 tggcccagca gaggctgcaa ctggaccgcg cacgacagga cctgccctct agcctcgtgg
     3481 gtctgttccc cagggcccag ggccctgcag cctccagcca gagtgccctc atgcctcctg
     3541 ctcccaccac ccgttggtgc agccagccgc caactggcct ggaccccagc cccttgcacc
     3601 tccatgccag gctggcactg ctgaggcaca tggcagagca ggaccgtgac ttcttggaga
     3661 atgaacagtt cttcctggag accctgaaga aagggtccta caatttgaca tctcattcag
     3721 cctgagtggg accccagccg attccccaac agagggttcg gaccccagaa ctgtcctgtt
     3781 cctccggctg cctccatgga ggcagtgcct ggggaggatt ctgagatgct tgaggcctga
     3841 tgacagctct tccgtggaca gggtgcaagt gcatcctttc caaatgtgcc agcccggggc
     3901 agcccctgcc tctggggctc tgtggtgtag gctatcttac catggctttg gctgccctgc
     3961 cccaaagcca ttggcttgga tctgagggtc tgagttggca gcaaggaccc ccagctctca
     4021 ctgggctctg tgggctcccc ctgggctctg tgggctcccc ctgctccaca ggtagactgt
     4081 tgtgggctct ttttgcctgg gcctcttctg aggcaggagc tttcttgagg gatgccacaa
     4141 acagccttcc ctactccctg ccagagcagt tccctccctg atgagctgga gaagggccct
     4201 ctggcctcct gacagtacag ggagggcacc agctagatcc tcccttgtgg tgtgagatgt
     4261 tcctggaact cagccaggcc ctcctcctcc tgggcttgcc cagagccccc accctattcc
     4321 cagcattgcc cgaaggacca accagtttgg gtgaacagtg gcctcctcag cttcctcccc
     4381 atctgggtgc cccaccggcg gcggagggag ctgtggcgat ggtggggtgt ggggagggac
     4441 gaggagggaa gcctctgtgc tgctcacctg cccaaagccc agctcagcgg gtacgcagtg
     4501 gaggcgacaa ggaaccaatc acaactacag aggtttctct gatcctcctc cactcccgct
     4561 gcttcaactt gactaagctt aaaaaaactg cttttgccat ggctcatcgg agtttatact
     4621 tatttcttag aaaatgtttc ctgttatttg ctggacaagt cccaaagaac aggcagatgt
     4681 tcttattaaa agatcagcct ataagattgg tcaggaccag gcgcctctgg ccacgtgcct
     4741 ctcccctcca gcacctgcgg tctgcggtgg cacctggcag ctggaccaca gccaggagaa
     4801 gggtactatt agccctgctt caaacatgca gaaactgagg cccggggaga ttaaataacc
     4861 tgcctgaaat gaca
//
