LOCUS       XM_006712169            6931 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens phenylalanyl-tRNA synthetase subunit beta
            (FARSB), transcript variant X1, mRNA.
ACCESSION   XM_006712169
VERSION     XM_006712169.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_006712169.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6931
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..6931
                     /gene="FARSB"
                     /gene_synonym="FARSLB; FRSB; HSPC173; NEDBLLA; PheHB;
                     PheRS; RILDBC; RILDBC1; RJBS"
                     /note="phenylalanyl-tRNA synthetase subunit beta; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 3 mRNAs, 95 ESTs, 1018 long SRA reads, 2 Proteins, and
                     94% coverage of the annotated genomic feature by RNAseq
                     alignments, including 62 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:10056"
                     /db_xref="HGNC:HGNC:17800"
                     /db_xref="MIM:609690"
     CDS             487..1959
                     /gene="FARSB"
                     /gene_synonym="FARSLB; FRSB; HSPC173; NEDBLLA; PheHB;
                     PheRS; RILDBC; RILDBC1; RJBS"
                     /codon_start=1
                     /product="phenylalanine--tRNA ligase beta subunit isoform
                     X1"
                     /protein_id="XP_006712232.1"
                     /db_xref="GeneID:10056"
                     /db_xref="HGNC:HGNC:17800"
                     /db_xref="MIM:609690"
                     /translation="MPDGKIQKLIITEETAKIRPFAVAAVLRNIKFTKDRYDSFIELQ
                     EKLHQNICRKRALVAIGTHDLDTLSGPFTYTAKRPSDIKFKPLNKTKEYTACELMNIY
                     KTDNHLKHYLHIIENKPLYPVIYDSNGVVLSMPPIINGDHSRITVNTRNIFIECTGTD
                     FTKAKIVLDIIVTMFSEYCENQFTVEAAEVVFPNGKSHTFPELAYRKEMVRADLINKK
                     VGIRETPENLAKLLTRMYLKSEVIGDGNQIEIEIPPTRADIIHACDIVEDAAIAYGYN
                     NIQMTLPKTYTIANQFPLNKLTELLRHDMAAAGFTEALTFALCSQEDIADKLGVDISA
                     TKAVHISNPKTAEFQVARTTLLPGLLKTIAANRKMPLPLKLFEISDIVIKDSNTDVGA
                     KNYRHLCAVYYNKNPGFEIIHGLLDRIMQLLDVPPGEDKGGYVIKASEGPAFFPGRCA
                     EIFARGQSVGKLGVLHPDVITKFELTMPCSSLEINVGPFL"
ORIGIN      
        1 gcagtgagtt cgacacacca tgccgactgt cagcgtgaag cgtgatctgc tcttccaagc
       61 cctgggccgc acctacactg acgaagaatt tgatgaacta tgttttgaat ttggtctgga
      121 gcttgatgaa attgtgcagt ttgtccactg atcaccagca tcgctgtgtt tggcccataa
      181 agaaggctgc ctcctatcag gaaaaaactg gagcaataca atgcaccgtg gaaggagaga
      241 gtggaactaa ttgaaaaagt cataactata caaaccagaa aatcactgga actgaagaaa
      301 aagacatctg agaaggaaat aataagtaaa gaacaaggta atgtaaaggc agcaggagcc
      361 tctgatgttg ttctttacaa aattgacgtc cctgccaata gatatgatct cctgtgtctg
      421 gaaggattgg ttcgaggact tcaggtcttc aaagaaagga taaaggctcc agtgtataaa
      481 cgggtaatgc ctgatggaaa aatccagaaa ttgattatca cagaagagac agctaagata
      541 cgtccttttg cggtagcagc agttctccgt aatataaagt ttactaaaga tcgatatgac
      601 agcttcattg aacttcagga gaaattacat cagaatattt gcaggaaaag agcactggtt
      661 gccattggta cccatgattt ggacactttg tcgggcccat ttacttatac tgcaaagcgt
      721 ccttcagata tcaaattcaa gcctctaaat aagaccaagg agtatacagc ctgtgaactg
      781 atgaacatat acaagactga caatcacctg aaacattatt tacatatcat tgaaaacaaa
      841 cccctgtatc cagttatcta tgatagcaat ggtgtcgtcc tttcaatgcc tcccatcatc
      901 aatggggatc attccagaat aacagtaaat actagaaata tttttattga atgcacggga
      961 actgacttta ctaaggcaaa aatagttctt gatattattg tcaccatgtt cagtgaatat
     1021 tgtgagaatc aatttacggt cgaagctgct gaagtggttt ttcctaatgg aaaatcacat
     1081 acctttccag aattagctta ccgaaaggag atggtgagag ctgacctaat taacaaaaaa
     1141 gttggaatca gagaaactcc agaaaatctt gccaaacttc tgaccaggat gtatttaaaa
     1201 tcagaagtca taggtgatgg gaatcagatt gagattgaaa tccctccaac cagagctgac
     1261 attatccatg catgtgatat tgtagaagat gcagctattg cttatggata taacaacatt
     1321 cagatgactc tcccgaaaac ttacaccata gctaatcaat ttcctcttaa taagctcact
     1381 gaacttctcc gacatgacat ggcagccgct ggcttcactg aagcacttac ctttgccctg
     1441 tgctcccaag aagatattgc tgataaacta ggtgtggata tctctgcaac aaaggcagtc
     1501 cacataagta atcctaaaac agctgaattt caggtggcac gcactaccct tcttcctggc
     1561 ctcctgaaga ccatagcagc aaatcgtaag atgccccttc cactgaaact gtttgaaatc
     1621 tctgacattg taataaaaga ttctaataca gatgtaggtg caaaaaacta cagacatctc
     1681 tgtgctgttt attacaacaa gaatcctggg tttgagatca ttcatgggct gctggacaga
     1741 attatgcagt tgctcgatgt gcctcctggt gaagacaagg ggggatatgt gatcaaagca
     1801 tcagaagggc ctgctttctt ccccgggcga tgtgcagaga tctttgccag gggtcaaagc
     1861 gtcgggaagc ttggggtcct tcatcctgac gttatcacca aatttgagct gaccatgccc
     1921 tgctcctccc tagaaatcaa tgttggaccc tttttgtgaa gattggtctc tgtggtgtga
     1981 ttctcttccc aggtgtccct ttctcctccc ctagtgtcct taagtcctcc tccacaggga
     2041 acatctattt gggctttgat gtttaataaa gtagaaagca ctgtctggct gtgtgggtag
     2101 agaccatcct ttccctgcat attaggccag cttgtgccat ataccagtgt ggtgtctgtg
     2161 tgtgaagctg cattgttggg taaaagcccc gtggagtgct ggagaaatgc actagcagag
     2221 tgcaggatct gttctgaaag gcagacgtgc tcctcagaca tcagaacatc acattggaac
     2281 ggattactcc tgcataacaa gatcccattt ctttccttat tgataaaaca agataatcga
     2341 tgagaattca tgttgcatga gttcgagata actgaggggt ttagctttga ttttctacat
     2401 ttgacatgta ttcatcattg agaaacacta aaataacaat atttttagaa aacgtttaag
     2461 aatcaattat ggtccaacaa ttatagcttc tgaggtcagt ttaaagtgaa agaaaaatct
     2521 gtaatacaag gattcaaaat atgtgagggt gcataggtat tttttactct atctgtgata
     2581 ctctaagata gagtacatgc aacaaagatc tgttctgctg taagagttaa aatggacaag
     2641 tattgatatc aatgcagtat gaacattagg aaacaatgag aagcttattt ttgccatagg
     2701 ccatacatgt tactgtaatc agtcagttat aaaatcatgg ttttaaatac ttaattgagc
     2761 tactagtttc tctattgtcc cagggagata ttagacctct ctttttctga agctaagctt
     2821 cagccaatcc tccttgtttt atatcctaat ttcctttctt acttcaatct agaattctcc
     2881 agtaggtacc atctctggaa aaaagctggg tctcatgttt gagacaagtt cccaggtact
     2941 attgaagtaa taagaaatat gataaaatat aatactttaa agtcccagta gaaatagcta
     3001 acaaaggctg ggtgcgctgt ggctcatgcc tgtaatccta gcactttggg aggctgaggt
     3061 gggcagatca cttgaggcca atagttcgag atcagcctga ccaacatggt gaaatgccat
     3121 ctccactaaa aatataaaaa ttagccaggc atggtggtgt gggcctgcag tcccagctac
     3181 ctgggaggct gagtcaggaa aatctcttga accaggaggt ggacgttgca gtgatcccag
     3241 attgtgccac tgccctccag cctgggtgac agagtgagat tctgtctaca aaaaaaaaaa
     3301 agaagaagta gctaacaaag atagtgaaat aagaattatg tttatggatc ttttgctgag
     3361 tctactacta ggagaaaacc tgaccatatt acaaccttga attggggcag cagtgtctaa
     3421 ctctgtaaga tttgtgaaca cacacacttc cagctgaccc ttcacagctc tgttataagc
     3481 agatccttac aacattttaa aaatgaaata tgccctctaa aaataatgca tgccaaaagg
     3541 acttgtatcc agcatgcata aagatttctt aaaacttaat aataaaactt aatagtaaaa
     3601 ataaaacaac tgttttttaa aaatgtgcaa gagttgagca aacatttccc aaaagatgac
     3661 atatgaatga gcacttgaaa agatcctcaa catcgttagt catcagggaa atgcaactaa
     3721 aattcacaat gacaaactgc atacccatta aaatggctaa aatttaagat tcataaatca
     3781 aatactgctg agactggagc aagtggaact ttcatgcact gctggtgagt cacaatgtaa
     3841 aatgttacat tgtgacttta gaaaacagct tggcagtctc ttgaaacata cacctaccat
     3901 ctagccattc tattcctagg tttacccata tggccaaaga tttttatgca agtgttcaca
     3961 gtgttactta tagtagttac aaattgcagt atatccatac tatgaaatac ttctcagcaa
     4021 taagaaggaa tgaactactg atcctcaaaa caacatgaat gaatttcaaa acagtatgct
     4081 aagtgaaagc aagagacaca aaagactcta tttaattcta tttacctgag agtctaaaaa
     4141 agtcaaaagc aggtggtcgg caggacctca ggaaagagaa ctgactgcag tgggttaaga
     4201 gaaaactttt tggggtgatg gaaattttat cttaattgag gtggtaggtg tacttcaggt
     4261 gtaggttata cctttgtaaa gctgggagaa aaagaatgta atgtaacatg tagtatttta
     4321 ctgattttaa ctacataaca ccagttgata aatgcctaga gaaatagcct gaactgtaga
     4381 attggcagtt gtgctcaagg tggctcactg gtccacagct attaatgata tattctccct
     4441 tagtttcagg ttcgctctag ttaaaatcat ggcttatgga tcatcatatg atagcccttg
     4501 ttgaagtagg tggaaccatt tgttctgtca gcagctaccc acctggatat ttttgggggt
     4561 ggccaaaatt acttgtaatg aaaaacccac taatgcctaa ttgtatatcc cagcatgaaa
     4621 ggggaaagat caactccatg catcatgtag atgtttctgc cctcggaagc aggaaatggt
     4681 aggcagaaaa acagtgtcgg ctgcattgga agaagcgaat ccagctcatg agtcgaggct
     4741 ctgcagccag atcatcttac acttgtccct ggtgaagcat ttgaactgga gccagggcag
     4801 tctgtgagta ctgccaaaag cctttattac agaagatgca caccttctta gtaaaaactg
     4861 ggagctctag tattaaagtg aaaattaaat ggaattgatt tttgttctag cttagaaaaa
     4921 acttaaattc taccactaca gcctcacagt cctgcagtgc tcttctagtt ttgtttgttt
     4981 tttgtttttt tagacggagt ctcgctctgt cacccaggct ggagtgcaat ggcacaatct
     5041 tggctcactg caacctccac ctcctgggtt caagcaattc tcctgcctca gcttcccgag
     5101 tagctgggac tacaggtgtg tgccaccatg cctggataat ttttgtattt ttagtagaga
     5161 cggggtttca ccacgttagc taggctggtc tcgaacttct gacctcaggc gatctgtcca
     5221 cctctgcctc ccaaagtgct gggattacag gcgcccagcc tgctcttctg tttttaaatt
     5281 atttttgaat tgatcttttt tcacatttta atttttttgg tttaataacg gtatgagagt
     5341 aggaattctc cctgatgtgt agggtgaaaa cagttgagtt tcagagagat caataactta
     5401 ctcagaagtc acatagccaa taaatgagtt tgagacacta taaaagagtg acttggagtc
     5461 cacagaccac tcactgattt gcattattta cttatttatg cgaaagtaaa taatgggact
     5521 ttctacactt tttaaaaata taaaaataat gggagacaaa aagttaaaaa ttgttaagtc
     5581 caatacttta aaaaaactct gcaaactgtg gccttactga gttaatctac ctttcttcct
     5641 cctgattccc tgaagtaact aactgctgtt aacaatttag cctgtattgt tccttagttt
     5701 ggacattttc cttgatttgt acagtcagcc acacacacct gctcacattt ttgggggtca
     5761 tgctctactt actggtttgc aacaagtttt gttttttatt ttacatatat ctcatgacat
     5821 ttcacttaat atgccccatt ttttcaggtc agtgcctata gacctatctc attcttttaa
     5881 atgaggtaat attctattgt acagatgtcc gtaattgttc aattattccc ttgttggtgg
     5941 acattcagtt gtttccaact gtttgcaatt ataaacactg ctccaatgaa ccccctatcc
     6001 tgctaaatag cactggctta ggaccccaag gaaaaccagt cctaatgggt gcaagactgt
     6061 ataaatatcc acatttgaca gacacattca gagatgcata gagttcatta gatatttctt
     6121 tgatgtgacg tttgtacttg aactatatat tattccagta ccttacatct tagatgtaga
     6181 agtcgctagg tcaaaggatg tgttttgaat ttaaaacatg ttgaatgact gttctcacat
     6241 tttaaacagg agtaatctac tacaaaccag ccagcctaac cactgcccct gctctcagca
     6301 atgatgggct catcagcttg gtaagagaga acattactca caatcttgct tctcaatctt
     6361 aatctatttg tgcttggtgt tttatataac atcactaacc ctaatacttg agtatttact
     6421 ttggcccttc tgtccatttt atccaaaagc aaacagatag ccttcaaggg acaccattgc
     6481 cttaagcaga atatgcctcc taagcattga aagcctttga cccatctgat atccaagttc
     6541 tggcttatta tgttattagg gccttgaata actttatgta tattattatg gactgaatgt
     6601 atccccacaa attcatgttg accctctgac ctccagtgtg atggtctttg gagatgaggc
     6661 ctttggcagg tgattagagc tagatgaggt catgagaggg aggccctcat gaaaggctca
     6721 gtggcctgat aagaagaaac accagagagc ttgctctgtt tctctgccta cctggcgcac
     6781 acatacagaa gaggtgatat gaccacacag caacatggtg gccaccagca agctaggaga
     6841 gggatcagaa tgaaacctat tttgctggca ccttgatctt gaaattctag cctccagaac
     6901 tgtgagaaat aaaattcttt tattgaagcc a
//
