LOCUS       XM_047432789            6139 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens FA complementation group I (FANCI),
            transcript variant X2, mRNA.
ACCESSION   XM_047432789
VERSION     XM_047432789.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000015.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6139
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
     gene            1..6139
                     /gene="FANCI"
                     /gene_synonym="KIAA1794"
                     /note="FA complementation group I; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     mRNAs, 67 ESTs, 2007 long SRA reads, 5 Proteins, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 12 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:55215"
                     /db_xref="HGNC:HGNC:25568"
                     /db_xref="MIM:611360"
     CDS             1353..5339
                     /gene="FANCI"
                     /gene_synonym="KIAA1794"
                     /codon_start=1
                     /product="Fanconi anemia group I protein isoform X1"
                     /protein_id="XP_047288745.1"
                     /db_xref="GeneID:55215"
                     /db_xref="HGNC:HGNC:25568"
                     /db_xref="MIM:611360"
                     /translation="MDQKILSLAAEKTADKLQEFLQTLREGDLTNLLQNQAVKGKVAG
                     ALLRAIFKGSPCSEEAGTLRRRKIYTCCIQLVESGDLQKEIASEIIGLLMLEAHHFPG
                     PLLVELANEFISAVREGSLVNGKSLELLPIILTALATKKENLAYGKGVLSGEECKKQL
                     INTLCSGRWDQQYVIQLTSMFKDVPLTAEEVEFVVEKALSMFSKMNLQEIPPLVYQLL
                     VLSSKGSRKSVLEGIIAFFSALDKQHNEEQSGDELLDVVTVPSGELRHVEGTIILHIV
                     FAIKLDYELGRELVKHLKVGQQGDSNNNLSPFSIALLLSVTRIQRFQDQVLDLLKTSV
                     VKSFKDLQLLQGSKFLQNLVPHRSYVSTMILEVVKNSVHSWDHVTQGLVELGFILMDS
                     YGPKKVLDGKTIETSPSLSRMPNQHACKLGANILLETFKIHEMIRQEILEQVLNRVVT
                     RASSPISHFLDLLSNIVMYAPLVLQSCSSKVTEAFDYLSFLPLQTVQRLLKAVQPLLK
                     VSMSMRDCLILVLRKAMFANQLDARKSAVAGFLLLLKNFKVLGSLSSSQCSQSLSVSQ
                     VHVDVHSHYNSVANETFCLEIMDSLRRCLSQQADVRLMLYEGFYDVLRRNSQLANSVM
                     QTLLSQLKQFYEPKPDLLPPLKLEACILTQGDKISLQEPLDYLLCCIQHCLAWYKNTV
                     IPLQQGEEEEEEEEAFYEDLDDILESITNRMIKSELEDFELDKSADFSQSTSIGIKNN
                     ICAFLVMGVCEVLIEYNFSISSFSKNRFEDILSLFMCYKKLSDILNEKAGKAKTKMAN
                     KTSDSLLSMKFVSSLLTALFRDSIQSHQESLSVLRSSNEFMRYAVNVALQKVQQLKET
                     GHVSGPDGQNPEKIFQNLCDITRVLLWRYTSIPTSVEESGKKEKGKSISLLCLEGLQK
                     IFSAVQQFYQPKIQQFLRALDVTDKEGEEREDADVSVTQRTAFQIRQFQRSLLNLLSS
                     QEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKICKENSREDALFCKSLMN
                     LLFSLHVSYKSPVILLRDLSQDIHGHLGDIDQDVEVEKTNHFAIVNLRTAAPTVCLLV
                     LSQAEKVLEEVDWLITKLKGQVSQETLSEEASSQATLPNQPVEKAIIMQLGTLLTFFH
                     ELVQTALPSGSCVDTLLKDLCKMYTTLTALVRYYLQVCQSSGGIPKNMEKLVKLSGSH
                     LTPLCYSFISYVQNKSKSLNYTGEKKEKPAAVATAMARVLRETKPIPNLIFAIEQYEK
                     FLIHLSKKSKVNLMQHMKLSTSRDFKIKGNILDMVLREDGEDENEEGTASEHGGQNKE
                     PAKKKRKK"
ORIGIN      
        1 aacggaagtg tggcggcgtt gggttgagcg ggctttttgg aagtttgtgg cggaggtgag
       61 gccgaggtga ctgcagagcg gctcgcgagg tgctcgggct gtgggactgg gcccctggga
      121 gggagcggtt ctgtggggga aaggaggctc ctgtcctgac ttggcgttct ggtattttct
      181 ctggcgtgga aagtaggcgc gctccgctgt ctcccgccgc ctgcctcagc tttcgcggtt
      241 ccctcctagg ggtgtgcctc agtcggagcc ccttctgtta aattcttccc ccttggccga
      301 gggtgagctc ttacttctga gaaatttccc ttaaccttgc tttgcatttg ttgtccggtc
      361 gcggtctcca tcaccagctg cttcgtgtta tagtttttgt atttgcgctc acggcttgtt
      421 aactgaagaa cccggaaggg aaggccgcgg cgtttcccgc cggcggggct ctgccattct
      481 cggatcttgg cttcagatct ctgatgctcc ccagcgtctc ttggcaagga atctacttcg
      541 cgttcaggga attcacagcc acccgcctct ggtcttacct ctggttttag gatgatttta
      601 gcaaatgtgc ctaggttgat ttaaacgtat ccccctccga agccgcctgc cccttctggc
      661 tggacacctt tttaggttgg tgtgtcctgt ttgcatccgg tagttcaaag catgggatct
      721 tggagtccgg agctggacag actcgggttt cacttctctc tctgccactt ggtagccttc
      781 taatcttggg ggaaattccc taatctctga atcccaaaag ttgttcatct aaaatggggc
      841 taatattaca cctacctagt aggtggtgtt gtgggagtca tgttaatgaa tgtaaagtgc
      901 tgggttcagt gttttcccta ttataggggt tcaataattt gttcaacaaa catttgttac
      961 ctagtttgag ctaggtactg tgctaagtgc tggagataca atgataaaca aaaccagcta
     1021 cggcccgtgt ccttagggga cttatagtct agtgggagat aacatttgtt aatctgataa
     1081 ttacacatgt aatattaaaa attggtgaca gtatgtaaga gagtttactg gtgccatgag
     1141 aggatgtact aggggaacgt ttaacaacct atactgagct tttcttttct tttcttttct
     1201 tttttttttg agacagagtc tccctctgtt gccaggctgg agtgcagtgg cgcgatctcg
     1261 gctcactgca acctccgcct cctgagttca agtgattctc ctgcctcagc ctcacaagta
     1321 gctgggacta cagttctgtg atatgagcaa caatggacca gaagatttta tctctagcag
     1381 cagaaaaaac agcagacaaa ctgcaagaat ttcttcaaac cctgagagaa ggtgatttga
     1441 ctaatctcct tcagaatcaa gcagtgaaag gaaaagttgc tggagcactc ctgagagcca
     1501 tcttcaaagg ttccccctgc tctgaggaag ctggaacact taggagacgt aagatataca
     1561 cttgttgtat ccagttggtg gaatcggggg atttgcagaa agaaatagcg tctgagatca
     1621 taggattact gatgctggag gctcaccatt ttccaggacc attattggtt gaattagcca
     1681 atgagtttat tagtgctgtc agagaaggca gcctagtgaa tggaaaatct ttggagttac
     1741 tacctatcat tctcactgcc ctggctacga aaaaggaaaa tctggcttat ggaaaaggtg
     1801 tactgagtgg ggaagaatgt aagaaacagt tgattaacac cctgtgttct ggcaggtggg
     1861 atcagcaata tgtaatccaa ctcacctcca tgttcaagga tgtccctctg actgcagaag
     1921 aggtggaatt tgtggtggaa aaagcattga gcatgttctc caagatgaat cttcaagaaa
     1981 taccaccttt ggtctatcag cttctggttc tctcctccaa gggaagcaga aagagtgttt
     2041 tggaaggaat catagccttc ttcagtgcac tagataagca gcacaatgag gaacagagtg
     2101 gtgacgagct attggatgtt gtcactgtgc catcaggtga acttcgtcat gtggaaggca
     2161 ccattattct acacattgtg tttgccatca aattggacta tgaactaggc agagaactcg
     2221 tgaaacactt aaaggtagga cagcaaggag attccaataa taacttaagt cccttcagca
     2281 ttgctcttct tctgtctgta acaagaatac aaagatttca ggaccaggtg cttgatcttt
     2341 taaagacttc ggttgtaaag agctttaagg atcttcaact cctccaaggc tcaaaatttc
     2401 ttcagaatct agttcctcat agatcttatg tttcaaccat gatcttggaa gtagtgaaga
     2461 atagcgttca tagctgggac catgttactc agggcctcgt agaacttggt ttcattttga
     2521 tggattcata tgggccaaag aaggttcttg atggaaaaac tattgaaacc agcccaagtc
     2581 tttctagaat gccaaaccag catgcatgta agctcggagc taatatcctg ttggaaactt
     2641 ttaagatcca tgagatgatc agacaagaaa ttttggagca ggtcctcaac agggttgtta
     2701 ccagagcatc ttctcccatc agtcatttct tagacctgct ttcaaatatc gtcatgtatg
     2761 cacccttagt tcttcaaagt tgttcttcta aagtcacaga agcttttgac tatttgtcct
     2821 ttctgcccct tcagactgta caaaggctgc ttaaggcagt gcagcccctt ctcaaagtca
     2881 gcatgtcaat gagagactgc ttgatacttg tccttcggaa agctatgttt gccaaccagc
     2941 ttgatgcccg aaaatctgca gttgctgggt ttttgctgct cctgaagaac tttaaagttt
     3001 taggcagcct gtcatcctct cagtgcagtc agtctctcag tgtcagtcag gttcatgtgg
     3061 atgttcacag ccattacaat tctgtcgcca atgaaacttt ttgccttgag atcatggata
     3121 gtttgaggag atgcttaagc cagcaagctg atgttcgact catgctttat gaggggtttt
     3181 atgatgttct tcgaaggaac tctcagctgg ctaattcagt catgcaaact ctgctctcac
     3241 agttaaaaca gttctatgag ccaaaacctg atctgctgcc tcctctgaaa ttagaagctt
     3301 gtattctgac ccaaggagat aagatctctc tacaagaacc actggattat ctgctgtgtt
     3361 gtattcagca ttgtttggcc tggtataaga atacagtcat acccttacag cagggagagg
     3421 aggaagagga ggaggaagag gcattctacg aagacctaga tgatatattg gagtccatta
     3481 ctaatagaat gattaagagt gagctggaag actttgaact ggataaatca gcagattttt
     3541 ctcagagcac cagtattggc ataaaaaata atatctgtgc ttttcttgtg atgggagttt
     3601 gtgaggtttt aatagaatac aatttctcca taagtagttt cagtaagaat aggtttgagg
     3661 acattctgag cttatttatg tgttacaaaa aactctctga cattcttaat gaaaaagcgg
     3721 gtaaagccaa aactaaaatg gccaacaaga caagtgatag tcttttgtcc atgaaatttg
     3781 tgtccagtct tctcactgct cttttcaggg atagtatcca aagccaccaa gaaagccttt
     3841 ctgttctcag gtccagcaat gagtttatgc gctatgcagt gaatgtagct ctgcagaaag
     3901 tacagcagct aaaggaaaca gggcatgtga gtggccctga tggccaaaac ccagaaaaga
     3961 tctttcagaa cctctgtgac ataactcgag tcttgctatg gagatacact tcaattccta
     4021 cttcagtgga agagtcggga aagaaagaga aaggaaagag catctcactg ctgtgcttgg
     4081 agggtttaca gaaaatattc agtgctgtgc aacagttcta tcagcccaag attcagcagt
     4141 ttctcagagc tctggatgtc acagataagg aaggagaaga gagagaagat gcagatgtca
     4201 gtgtcactca gagaacagca ttccagatcc ggcaatttca gaggtccttg ttgaatttac
     4261 ttagcagtca agaggaagat tttaatagca aagaagccct cctgctagtc acggttctta
     4321 ccagtttgtc caagttactg gagccctcct ctcctcagtt tgtgcagatg ttatcctgga
     4381 catcaaagat ttgcaaggaa aacagccggg aggatgcctt gttttgcaag agcttgatga
     4441 acttgctctt cagcctgcat gtttcgtata agagtcctgt cattctgctg cgtgacttgt
     4501 cccaggatat ccacgggcat ctgggagata tagaccagga tgtagaggtg gagaaaacaa
     4561 accactttgc aatagtgaat ttgagaacgg ctgcccccac tgtctgttta cttgttctga
     4621 gtcaggccga gaaggttcta gaagaagtgg actggctaat caccaagctt aagggacaag
     4681 tgagccaaga aaccttatca gaagaggcct cttctcaggc aaccctacca aatcagcctg
     4741 ttgagaaagc tatcatcatg caactgggaa ctctgcttac atttttccac gagctggtgc
     4801 agacagctct gccatcaggc agctgtgtgg acaccttgtt aaaggacttg tgcaaaatgt
     4861 acaccacact tacagccctt gtcagatatt atctccaggt gtgtcagagc tccggaggaa
     4921 ttccaaaaaa tatggaaaag ctggtgaagc tgtctggttc tcatctgacc cccctgtgtt
     4981 attctttcat ttcttacgta cagaataaga gtaagagcct gaactatacg ggagagaaaa
     5041 aggagaaacc tgctgccgtt gccacagcca tggccagagt tcttcgggaa accaagccaa
     5101 tccctaacct catctttgcc atagaacagt atgaaaaatt tctcatccac ctttctaaga
     5161 agtccaaggt gaacctgatg cagcacatga agctcagcac ctcacgagac ttcaagatca
     5221 aaggaaacat cctagacatg gttcttcgag aggatggtga agatgaaaat gaagagggca
     5281 ctgcatcaga gcatggggga cagaacaaag aaccagccaa gaagaaaagg aaaaaataaa
     5341 tgaaatgcct gagttaatgt gaactttggg gcttctgctt catttttacc caacaagcaa
     5401 caatgcccct tgtcctgtag tccacaccga tgttggcatc ttggttctga acccactgaa
     5461 ttcaactgca ccttcagtta gaaggaatct tcttggcagg tcctgctact gaaaaatggc
     5521 tggccttagg caagcccttt tgcaaaaagc acagctgaaa gcctgagttt gggagcctgc
     5581 accaccccga tgaagctcca cgggagcaaa tacagagcct ccaggcagtg ctatggtcca
     5641 ggctggcttc gtttttccaa ggagcctttg gtgagttcaa ttatctggta aatatccagc
     5701 gcttcacctg aaagatagtg caaattggtt aggatgccac ctcaagaact gtaactgaga
     5761 gctcagaagt gagcaaagga gcttaatgct aaggtcaaaa ggagagtgaa aggttgagaa
     5821 caattgccac gaacggtaat gttacatgtt aggagggtct gttttctttt tatataagtg
     5881 tgtcttagat atattttaaa tagaaaataa gctttctgat ttacttgttt ggtatttaaa
     5941 gcacagtttg tttttctgtc acctatagag tgcaagaatg cactctatag aataaattat
     6001 ctttaaacat ttcttctgtg gttgaagtag gggacaggta caggtagaat atttgaagct
     6061 ctgctgcctt catttctgaa acatcatatc acattcactc tggacacagg gcaccttata
     6121 aactgaaatt agcctagaa
//
