LOCUS       NM_198552               1503 bp    mRNA    linear   PRI 09-FEB-2025
DEFINITION  Homo sapiens family with sequence similarity 89 member A (FAM89A),
            mRNA.
ACCESSION   NM_198552 XM_351326
VERSION     NM_198552.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Bhat,A., Irizar,H., Thygesen,J.H., Kuchenbaecker,K., Pain,O.,
            Adams,R.A., Zartaloudi,E., Harju-Seppanen,J., Austin-Zimmerman,I.,
            Wang,B., Muir,R., Summerfelt,A., Du,X.M., Bruce,H., O'Donnell,P.,
            Srivastava,D.P., Friston,K., Hong,L.E., Hall,M.H. and Bramon,E.
  TITLE     Transcriptome-wide association study reveals two genes that
            influence mismatch negativity
  JOURNAL   Cell Rep 34 (11), 108868 (2021)
   PUBMED   33730571
  REMARK    GeneRIF: Transcriptome-wide association study reveals two genes
            that influence mismatch negativity.
REFERENCE   2  (bases 1 to 1503)
  AUTHORS   Gomez-Carballa,A., Cebey-Lopez,M., Pardo-Seco,J., Barral-Arca,R.,
            Rivero-Calle,I., Pischedda,S., Curras-Tuala,M.J., Gomez-Rial,J.,
            Barros,F., Martinon-Torres,F. and Salas,A.
  TITLE     A qPCR expression assay of IFI44L gene differentiates viral from
            bacterial infections in febrile children
  JOURNAL   Sci Rep 9 (1), 11780 (2019)
   PUBMED   31409879
  REMARK    GeneRIF: A qPCR expression assay of IFI44L gene differentiates
            viral from bacterial infections in febrile children.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1503)
  AUTHORS   Herberg,J.A., Kaforou,M., Wright,V.J., Shailes,H.,
            Eleftherohorinou,H., Hoggart,C.J., Cebey-Lopez,M., Carter,M.J.,
            Janes,V.A., Gormley,S., Shimizu,C., Tremoulet,A.H.,
            Barendregt,A.M., Salas,A., Kanegaye,J., Pollard,A.J., Faust,S.N.,
            Patel,S., Kuijpers,T., Martinon-Torres,F., Burns,J.C., Coin,L.J.
            and Levin,M.
  CONSRTM   IRIS Consortium
  TITLE     Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for
            Discriminating Bacterial vs Viral Infection in Febrile Children
  JOURNAL   JAMA 316 (8), 835-845 (2016)
   PUBMED   27552617
  REMARK    Erratum:[JAMA. 2017 Feb 7;317(5):538. doi:
            10.1001/jama.2016.18601.. PMID: 28170459]
REFERENCE   4  (bases 1 to 1503)
  AUTHORS   Della-Morte,D., Wang,L., Beecham,A., Blanton,S.H., Zhao,H.,
            Sacco,R.L., Rundek,T. and Dong,C.
  TITLE     Novel genetic variants modify the effect of smoking on carotid
            plaque burden in Hispanics
  JOURNAL   J Neurol Sci 344 (1-2), 27-31 (2014)
   PUBMED   24954085
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL732414.17, BC009447.1 and CD365446.1.
            
            On Nov 22, 2018 this sequence version replaced NM_198552.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC009447.1, ERR279863.4533.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000366654.5/ ENSP00000355614.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                AL732414.17        46760-46774         c
            16-794              BC009447.1         1-779
            795-1499            AL732414.17        25482-26186         c
            1500-1503           CD365446.1         19-22               c
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q42.2"
     gene            1..1503
                     /gene="FAM89A"
                     /gene_synonym="C1orf153"
                     /note="family with sequence similarity 89 member A"
                     /db_xref="GeneID:375061"
                     /db_xref="HGNC:HGNC:25057"
     exon            1..334
                     /gene="FAM89A"
                     /gene_synonym="C1orf153"
                     /inference="alignment:Splign:2.1.0"
     CDS             44..598
                     /gene="FAM89A"
                     /gene_synonym="C1orf153"
                     /codon_start=1
                     /product="protein FAM89A"
                     /protein_id="NP_940954.1"
                     /db_xref="CCDS:CCDS1590.1"
                     /db_xref="GeneID:375061"
                     /db_xref="HGNC:HGNC:25057"
                     /translation="MSGARAAPGAAGNGAVRGLRVDGLPPLPKSLSGLLHSASGGGAS
                     GGWRHLERLYAQKSRIQDELSRGGPGGGGARAAALPAKPPNLDAALALLRKEMVGLRQ
                     LDMSLLCQLYSLYESIQEYKGACQAASSPDCTYALENGFFDEEEEYFQEQNSLHDRRD
                     RGPPRDLSLPVSSLSSSDWILESI"
     exon            335..1503
                     /gene="FAM89A"
                     /gene_synonym="C1orf153"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1485..1490
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM89A"
                     /gene_synonym="C1orf153"
                     /note="hexamer: GATAAA"
     polyA_site      1503
                     /gene="FAM89A"
                     /gene_synonym="C1orf153"
                     /note="major polyA site"
ORIGIN      
        1 ggttcgctgc agcggggcag gcgcgtggcc gggccgcggc gcgatgagtg gggcccgggc
       61 ggcgcccggg gccgcgggca acggcgcggt ccgggggctg cgggtggacg ggctgccccc
      121 gctgccaaag agcttgagcg ggctgctgca ctcggcgtcg ggcggcggcg cgtctggggg
      181 ctggcggcac ctggagcggc tgtacgcgca gaagtcgcgc atccaggacg agctgagccg
      241 cgggggcccg ggcggcggcg gggcccgggc ggcagcgctg cccgccaagc ctcccaacct
      301 ggacgccgct ctggcgctgc tccgcaaaga gatggttggt ctccgccagc tggacatgtc
      361 cttgctctgc caactgtaca gcctctacga gtcgattcag gagtacaagg gggcatgcca
      421 ggcagcctcc agcccagact gcacttacgc tctggagaac ggcttcttcg atgaagagga
      481 ggaatatttc caggagcaga actccctgca cgacaggagg gaccgaggcc ctcctcggga
      541 cttgtcactg cctgtctcct ccctctccag cagcgactgg attctggagt ccatctagag
      601 ggtcttggga gggatgtgac tgttgggaag cccttcctac tggacacgct gtcatcattt
      661 gctgcttctc ttgcaagaaa gcacctccgt tgtggacggt cctcgggcac aggggatgag
      721 cgctaccagt ttcatttgta ggcagggagt tctccgcgga tgcatggtgg cagtctgctt
      781 tgatggcagc agtttctgct taggtgacct agaggtcctc agcagtatcc tccacaccta
      841 tttattgagg tgcacctgct ggggattcat aatgagaata taacaagagg atctcggtga
      901 aaggccttag tgggtgtttt gtgtgaggtg gcttgtagct agctacttcc ttacagatgg
      961 tagagtattc caatcctctt tgtgttaggg ttcttgcttc cagtttggga tgtattaaaa
     1021 ccaccatttc actgcttccc ttcctcaata tgctctgcag cttttcttgc tgtttaaacc
     1081 tctcgcctca gctttattta tttgtaagct gcattactaa ctgcccagtg attcggtgaa
     1141 agctttttac tgaaaaagtt aacatttcta gtcatcccaa tcaactggct tttttcaacc
     1201 aaaattttat atcattcttt gtctatcaga tacgagagga aggaagataa tacgaagaca
     1261 tgttgaatag tgaaaaaaaa aaaaagaaca caaaaactgg ggcaagccaa tgtgatgtat
     1321 cactcactgt aagatggcaa atgttttcat ttttaagatt ccgaatgtaa actagtgtgc
     1381 tagaaagcaa accacccgcc actcaaacca gtaattacct taagccttaa tatatttatt
     1441 aaaatacttt atgagaacat tacactttgt aggttaaaaa tgaggataaa atgctaaact
     1501 atc
//
