LOCUS       NM_001287385            2395 bp    mRNA    linear   PRI 17-FEB-2024
DEFINITION  Homo sapiens family with sequence similarity 72 member C (FAM72C),
            transcript variant 1, mRNA.
ACCESSION   NM_001287385 XM_003846498 XM_003960201
VERSION     NM_001287385.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2395)
  AUTHORS   Kutzner,A., Pramanik,S., Kim,P.S. and Heese,K.
  TITLE     All-or-(N)One - an epistemological characterization of the human
            tumorigenic neuronal paralogous FAM72 gene loci
  JOURNAL   Genomics 106 (5), 278-285 (2015)
   PUBMED   26206078
  REMARK    GeneRIF: An epistemological characterization of the human
            tumorigenic neuronal paralogous FAM72 gene loci (FAM72A, FAM72B,
            FAM72C, FAM72D).
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC246680.1.
            
            On Nov 20, 2020 this sequence version replaced NM_001287385.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3218372.928424.1,
                                           SRR7410570.29273.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000584486.6/ ENSP00000463032.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-997               AC246680.1         87204-88200         c
            998-1075            AC246680.1         85138-85215         c
            1076-1200           AC246680.1         81069-81193         c
            1201-2395           AC246680.1         71501-72695         c
FEATURES             Location/Qualifiers
     source          1..2395
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q21.1"
     gene            1..2395
                     /gene="FAM72C"
                     /note="family with sequence similarity 72 member C"
                     /db_xref="GeneID:554282"
                     /db_xref="HGNC:HGNC:30602"
                     /db_xref="MIM:616853"
     exon            1..997
                     /gene="FAM72C"
                     /inference="alignment:Splign:2.1.0"
     CDS             846..1295
                     /gene="FAM72C"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein FAM72C; RP5-998N21.9"
                     /codon_start=1
                     /product="protein FAM72C isoform 1"
                     /protein_id="NP_001274314.1"
                     /db_xref="CCDS:CCDS72850.1"
                     /db_xref="GeneID:554282"
                     /db_xref="HGNC:HGNC:30602"
                     /db_xref="MIM:616853"
                     /translation="MSTNICSFKDRCVSILCCKFCKQVLSSRGMKAVLLADTEIDLFS
                     TDIPPTNAVDFTGRCYFTKICKCKLKDIACLKCGNIVVYHVIVPCSSCLLSCNNRHFW
                     MFHSQAVYDINRLDSTGVNVLLRGNLPEIEESTDEDVLNISAEECIR"
     exon            998..1075
                     /gene="FAM72C"
                     /inference="alignment:Splign:2.1.0"
     exon            1076..1200
                     /gene="FAM72C"
                     /inference="alignment:Splign:2.1.0"
     exon            1201..2395
                     /gene="FAM72C"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2371..2376
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM72C"
                     /note="hexamer: AATAAA"
     polyA_site      2395
                     /gene="FAM72C"
                     /note="major polyA site"
ORIGIN      
        1 aggaaaagcg gaagagggag cgaaaaccaa cgtgttcggt gacagacccc agcgccgact
       61 gagcctctaa agcgacttca gctctgcccc accaacacca ccgcgcgccc gggaacagcc
      121 gctccgggaa gaaacctgag gggactgcgg ggggcacgag ggacagctga gggaagggag
      181 gacgcgagag aaacagcgcg agcacgctga gggccggggg ttgccaggag aggggcccgc
      241 ggacccgcag agcggaggaa ggtccgggag aaaaggggcg ggacggagga gaatccggga
      301 tcgcctggca gaaaaagaga agggagtttc tgaatcctgg gaagaggagg cgtgggtagg
      361 gacgcttagc ccgagatccg acagcaggga accggagcgc tccgggggag gggcttaatg
      421 ctggggaagg gatgtcttaa aagaggagaa gctttaaatt agacgatcgg agaaggctga
      481 gggaattgct atgaaggggc gggagctgaa gtgtagagga ctcctttaga cagcagaaag
      541 ggaaagccgt tgagaagttc ccttcaaact ccacctgcct cctctccaat tcaaactcca
      601 ctcccttctc caaaagttaa aaggaaagcc aagtttgcca cgctcccctg ttcctactca
      661 ataaatactt cttctactcc gccaccggga aaacagaaaa aaaaactaat ttccttccca
      721 atattaggac ttagaaaagc tctaggtccc gcaatttgaa ttttagccta ggggaatcaa
      781 aatagtagga gcattactct tgtttccttt ttcaaaatcc cacacctcat ccttcctgcg
      841 acgccatgtc caccaacatt tgtagtttca aggacaggtg cgtgtccatc ctgtgttgca
      901 aattctgtaa acaagtgctc agctctaggg gaatgaaggc tgttttgctg gctgatactg
      961 aaatagacct tttctctaca gacatccctc ctaccaacgc agtggacttc actggaagat
     1021 gctatttcac caaaatctgc aaatgtaaac tgaaggacat cgcatgttta aaatgtggga
     1081 acattgtagt ttatcatgtg attgttccat gtagttcctg tcttctttcc tgcaacaaca
     1141 gacacttctg gatgtttcac agccaggcag tttatgatat taacagacta gactccacag
     1201 gtgtaaacgt cctacttcgg ggcaacttgc cagagataga agagagtaca gatgaagatg
     1261 tgttaaatat ctcagcagag gagtgtatta gataaatgga attatgatat atatgatata
     1321 caaacttttt tctatttaaa aatatattaa tggatcaact ttaaaattgt tagttgccag
     1381 tgatcttttt tggaaaacaa aaatggggca tttgttgatt tatttatttt ctgtctctaa
     1441 ttagttacct cagtttgatt gaagccagtg gagttgtgct tttcctctac ttctacttcc
     1501 tctcccccac ctttttctgc ccagtgtagg tgtattctta aattcagacg ggaagattct
     1561 ttcacatatc actcagttac ctcccaatct gggggagttt ttcttacaac ttgataccag
     1621 ataccattaa ttttacattc ctgaataaag gcctagtacc cacgcatatt tcaaccatgc
     1681 atatatcaag ttcaaccgag ttttaatagg ggattaaaaa aacaagctgt taggtttcca
     1741 tgggcactgg ttctcatagg ttctattggt gataactgct ttaacatgga gcaagagttt
     1801 gtgaatcagg aaatagaata aattaaaatt taaaatatat agaggaatcc tcttgattgc
     1861 tcagcatgat gttagataaa tgagtttgtc agaaaatatc agtatacgct gtttaccaat
     1921 gttatttatt tacattcttc taaagccatt atggatattg tattatgaga gctaaaccta
     1981 aataagttat cctgttccct aggaccttct ctgtaaatag tgaattttag acgagtagtc
     2041 tgtcctaaat cttaaataga aaaaaaaact aaagcgattt gcttaagcca ttgtacatta
     2101 taaagagctg ttttgttttg ctttgctttg ctttgttttg ttttttttaa agctgcattc
     2161 agagccacaa aggaatagga aagtagggta gtgttggatt ctggttttat gtaactctaa
     2221 aataaatgta tctctttaat atctcagttg tagggatttt gtcaatacca aagcagactg
     2281 agttgtggtt ttgtaaataa agttttttct aaaaatgacc attcttcctt taattttttg
     2341 ttatgcccac atattgtatg taaaaatata aataaatggt acttaaagta tagaa
//
