LOCUS       NM_001013736            3299 bp    mRNA    linear   PRI 15-FEB-2024
DEFINITION  Homo sapiens family with sequence similarity 47 member C (FAM47C),
            mRNA.
ACCESSION   NM_001013736 XM_498355
VERSION     NM_001013736.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3299)
  AUTHORS   Chertman,W., Arora,H., Griswold,A.J., Lopategui,D.M. and
            Ramasamy,R.
  TITLE     Whole Exome Sequencing Identifies a Rare Nonsense Mutation in
            FAM47C as a Possible Cause of Severe Oligospermia in Brothers With
            Varicocele
  JOURNAL   Urology 129, 71-73 (2019)
   PUBMED   30922974
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX842568.3.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Dec 4, 2019 this sequence version replaced NM_001013736.2.
            
            Summary: This gene encodes a product belonging to a family of
            proteins with unknown function. The coding sequence of this family
            member includes several tandemly repeated regions. [provided by
            RefSeq, Sep 2011].
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK125992.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000358047.5/ ENSP00000367913.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3299              BX842568.3         67052-70350         c
FEATURES             Location/Qualifiers
     source          1..3299
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xp21.1"
     gene            1..3299
                     /gene="FAM47C"
                     /note="family with sequence similarity 47 member C"
                     /db_xref="GeneID:442444"
                     /db_xref="HGNC:HGNC:25301"
                     /db_xref="MIM:301067"
     exon            1..3299
                     /gene="FAM47C"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..3153
                     /gene="FAM47C"
                     /codon_start=1
                     /product="putative protein FAM47C"
                     /protein_id="NP_001013758.1"
                     /db_xref="CCDS:CCDS35227.1"
                     /db_xref="GeneID:442444"
                     /db_xref="HGNC:HGNC:25301"
                     /db_xref="MIM:301067"
                     /translation="MGDQRPQDRPSSPGMDSTPWYCDKPPSKYFAKRKHRRLRFPPVD
                     TQNWVFVTEGMDDFRYGCQSPEDTLVCRRDEFLLPKISLRGPQADPKSRKKKLLKKAA
                     LFSKLSPAQPARKAFVEEVEAQLMTKHPLAMYPNLGEDMPPDLLLQVLKPLDPERKLE
                     DAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETG
                     VSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPG
                     TGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEP
                     PKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRP
                     ETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHL
                     RPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVS
                     HLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTR
                     MYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPE
                     TGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEP
                     PETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRP
                     EPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSS
                     LRLEPPKTGRVSSLCPEPTKTGASHLKELFQEGTSSTMECVSDSLQRRHTSRKLRDFK
                     WAGDLGVNEESISSLFDFTPECRATYQDQKNKKANECSSGLKYSMELDEMDEVKFFSQ
                     EKDLDGKIQNAPNSHSAQHVKMGYGAWYLKPKLGKKLRSDEPLIDPKLVLEKPDEPDI
                     LDGLYGPIAFKDFILSKGYEMPGIIQRLFARRGWTYDSVKTPIQRAMQVYKYKEDVTD
                     ASEED"
ORIGIN      
        1 aggaaccgcg gaaactggag aggtggcacc ccagcgaggg ccaccatggg ggaccagagg
       61 ccgcaggacc ggcccagttc cccgggcatg gactccacgc cctggtactg tgacaaaccg
      121 ccttccaagt acttcgcgaa gcgcaagcac aggcgcctga ggttcccgcc tgtggacacc
      181 cagaactggg tatttgtgac ggagggcatg gacgacttcc gctacggctg tcagtctcct
      241 gaagatacgc ttgtttgtcg ccgtgacgag tttttactcc ccaaaatatc tctcagaggt
      301 ccccaagctg accccaaaag caggaagaaa aagctgctca agaaagcggc cctgttttcc
      361 aagctctcgc cagcacagcc agcacggaag gcgttcgtag aggaagtgga agcccagctg
      421 atgaccaagc atcccttggc catgtacccc aatctgggag aagatatgcc tccagatctc
      481 ctactacagg tactgaaacc gctggaccct gagaggaagc tggaggacgc aggctcttgt
      541 gagggccagg agaagacaac tgacgaaccc acggagcctg gtaaataccc ctgtggggaa
      601 ttctcccctc ggcctcccga gactcgggtg tcctgtctcc ccccggagcc tcccaagact
      661 ccggtgtcca gtctccgccc ggagcctcca gagactggag tgtcccatct ccgcccacag
      721 cctcccaaga ctcaggtgtc cagtctccac ctggagcctc cagagactgg agtgtcccat
      781 ctccgcccag agcctcccaa gactcaggtg tccagtctcc acctggagcc tcccgagact
      841 ggagtgtccc atctctacct ggagcctcct gggactggag tgtctcatct ctgcccagag
      901 cctcccaaga ctcgcgtatc tcatctccat cgggagcctc ctgagactgg agtgcctgat
      961 ctctgcctgg agcctcccaa gtcacgcgta tctcatctcc gcccagagcc ttctgagact
     1021 ggagtgtccc atctccaccc agagcctccc aagactctgg tgtccagtct ccacccagag
     1081 cctcccgaga ctggagtgtc ccatctctgc ccggaacctc cagagactcg cgtatctcct
     1141 ctccgccagc tgcctcccga ggctggagtg tcccatctct gcccggaacc tcccaagact
     1201 cgcgtacctc ctctccgccc agagaccccc aagaatggag tgtctcctct cttcccggag
     1261 cctcccaaga ctcgcatatc taatctccgc tcggagcctc ccaagattgg agtgtcccat
     1321 ctctgcctgg agcctcccaa gactcgcgga tctcatctcc gcccggaacc tcctgagact
     1381 ggagtgtccc atctccgccc agagcctccc aagactcggg tgtccagtct ccacctggag
     1441 cctcctgaga ctggagtgtc ccatctctgc ccggagcctc cagagaagga cgtatctcat
     1501 ctccgcccag agcctcccga cactggagtg tcccatctct gcccagagcc ccccaagaca
     1561 cgcgtatctc atctccgccc agagccttct gagactggag tgtcccatct ccgcccagag
     1621 cctcccaaga ttctggtgtc cagtctccac caggcacctc ctgagagtag cgtatctcat
     1681 ctccgcccag agcctcctga gactggagtg tcccatctcc gcccagagcc tcccaagact
     1741 cggatgtaca gtctccgccc ggagcctccc gatactggag tgtcccatct ctgcccagag
     1801 cctcccaaga ctcgggtgtc cagtctcccc ccggagcccc ccgagactgg agtgtcccat
     1861 ctctgcccgg agcctccaga gactcgcgta tctcatctcc gcccagagcc tcctgagact
     1921 ggagtgtccc atctccgccc agagcctccc aagactcgga tgtacagtct ccgcccggag
     1981 cctcccaata ctggagtgtc ccatctctgc ccagagcctc ccaagactcg ggtgtccagt
     2041 ctccccccgg agccccccga gactggagtg tcccatctct gcccggagcc tccagagact
     2101 cgcgtatctc atctccgccc agagcctcct gagactggag tgtcccgtct ccacccagag
     2161 cctcccaaga ctcgggtgtc cagtctccac gcggagcctc ctgagagtcg cgtatctcat
     2221 ctctgcccgg agcctcctga gactggagtg tcccatctcc gcccagagcc tcccaagcct
     2281 cgggtttcca gtctccgccc agagcctctt gagactcgcg tatctcatct ccgcccggag
     2341 cctcctgaga ctggagtgtc ccatctccac ccagagcttc ccaagcctcg ggtatccagt
     2401 ctccacctgg agcctcccaa gactcgtcga gtgtccagtc tccgcctgga gcctcccaag
     2461 actggtcggg tgtccagtct ctgcccggag cctaccaaga ccggagcgtc ccatctaaaa
     2521 gaactgtttc aggaaggtac atcaagcaca atggagtgtg tttctgactc tcttcaacgt
     2581 agacacacat cgagaaaact ccgtgacttc aagtgggctg gagacctagg agttaatgaa
     2641 gaatccatca gcagtctgtt tgactttacc cctgagtgca gagcaaccta tcaagaccaa
     2701 aagaataaga aggcaaacga gtgttcctca gggctgaagt acagcatgga gctagacgaa
     2761 atggatgagg tcaaattctt ctcacaggaa aaagacttgg acgggaaaat ccagaatgca
     2821 ccaaattctc atagtgcaca gcatgtgaag atggggtatg gagcatggta cctcaagcct
     2881 aagttgggga aaaagctaag aagtgatgaa cctttgattg accccaagct cgtacttgaa
     2941 aagcctgatg aacccgacat tcttgacggt ctttatggac caatcgcctt taaggatttc
     3001 attctaagca agggctatga aatgcctggc atcattcaaa ggctgtttgc caggagggga
     3061 tggacttatg actctgttaa gactcctatt caacgtgcaa tgcaagttta caagtacaaa
     3121 gaagacgtca cagatgcatc ggaagaagat tagatggttt tgaatttact agttaattgg
     3181 gtatttcttg ctctcatttt aaacatcagt cagaatttat gatgactggc cccaggaatg
     3241 tacaacgttg gcaacatctg taaattcaat acctaatgtt tataaatatt tcttaatga
//
