LOCUS       NM_152631               2120 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens family with sequence similarity 47 member B (FAM47B),
            mRNA.
ACCESSION   NM_152631
VERSION     NM_152631.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2120)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2120)
  AUTHORS   Ross,M.T., Grafham,D.V., Coffey,A.J., Scherer,S., McLay,K.,
            Muzny,D., Platzer,M., Howell,G.R., Burrows,C., Bird,C.P.,
            Frankish,A., Lovell,F.L., Howe,K.L., Ashurst,J.L., Fulton,R.S.,
            Sudbrak,R., Wen,G., Jones,M.C., Hurles,M.E., Andrews,T.D.,
            Scott,C.E., Searle,S., Ramser,J., Whittaker,A., Deadman,R.,
            Carter,N.P., Hunt,S.E., Chen,R., Cree,A., Gunaratne,P., Havlak,P.,
            Hodgson,A., Metzker,M.L., Richards,S., Scott,G., Steffen,D.,
            Sodergren,E., Wheeler,D.A., Worley,K.C., Ainscough,R.,
            Ambrose,K.D., Ansari-Lari,M.A., Aradhya,S., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Ballabio,A., Banerjee,R., Barker,G.E.,
            Barlow,K.F., Barrett,I.P., Bates,K.N., Beare,D.M., Beasley,H.,
            Beasley,O., Beck,A., Bethel,G., Blechschmidt,K., Brady,N.,
            Bray-Allen,S., Bridgeman,A.M., Brown,A.J., Brown,M.J., Bonnin,D.,
            Bruford,E.A., Buhay,C., Burch,P., Burford,D., Burgess,J.,
            Burrill,W., Burton,J., Bye,J.M., Carder,C., Carrel,L., Chako,J.,
            Chapman,J.C., Chavez,D., Chen,E., Chen,G., Chen,Y., Chen,Z.,
            Chinault,C., Ciccodicola,A., Clark,S.Y., Clarke,G., Clee,C.M.,
            Clegg,S., Clerc-Blankenburg,K., Clifford,K., Cobley,V., Cole,C.G.,
            Conquer,J.S., Corby,N., Connor,R.E., David,R., Davies,J., Davis,C.,
            Davis,J., Delgado,O., Deshazo,D., Dhami,P., Ding,Y., Dinh,H.,
            Dodsworth,S., Draper,H., Dugan-Rocha,S., Dunham,A., Dunn,M.,
            Durbin,K.J., Dutta,I., Eades,T., Ellwood,M., Emery-Cohen,A.,
            Errington,H., Evans,K.L., Faulkner,L., Francis,F., Frankland,J.,
            Fraser,A.E., Galgoczy,P., Gilbert,J., Gill,R., Glockner,G.,
            Gregory,S.G., Gribble,S., Griffiths,C., Grocock,R., Gu,Y.,
            Gwilliam,R., Hamilton,C., Hart,E.A., Hawes,A., Heath,P.D.,
            Heitmann,K., Hennig,S., Hernandez,J., Hinzmann,B., Ho,S., Hoffs,M.,
            Howden,P.J., Huckle,E.J., Hume,J., Hunt,P.J., Hunt,A.R.,
            Isherwood,J., Jacob,L., Johnson,D., Jones,S., de Jong,P.J.,
            Joseph,S.S., Keenan,S., Kelly,S., Kershaw,J.K., Khan,Z.,
            Kioschis,P., Klages,S., Knights,A.J., Kosiura,A., Kovar-Smith,C.,
            Laird,G.K., Langford,C., Lawlor,S., Leversha,M., Lewis,L., Liu,W.,
            Lloyd,C., Lloyd,D.M., Loulseged,H., Loveland,J.E., Lovell,J.D.,
            Lozado,R., Lu,J., Lyne,R., Ma,J., Maheshwari,M., Matthews,L.H.,
            McDowall,J., McLaren,S., McMurray,A., Meidl,P., Meitinger,T.,
            Milne,S., Miner,G., Mistry,S.L., Morgan,M., Morris,S., Muller,I.,
            Mullikin,J.C., Nguyen,N., Nordsiek,G., Nyakatura,G., O'Dell,C.N.,
            Okwuonu,G., Palmer,S., Pandian,R., Parker,D., Parrish,J.,
            Pasternak,S., Patel,D., Pearce,A.V., Pearson,D.M., Pelan,S.E.,
            Perez,L., Porter,K.M., Ramsey,Y., Reichwald,K., Rhodes,S.,
            Ridler,K.A., Schlessinger,D., Schueler,M.G., Sehra,H.K.,
            Shaw-Smith,C., Shen,H., Sheridan,E.M., Shownkeen,R., Skuce,C.D.,
            Smith,M.L., Sotheran,E.C., Steingruber,H.E., Steward,C.A.,
            Storey,R., Swann,R.M., Swarbreck,D., Tabor,P.E., Taudien,S.,
            Taylor,T., Teague,B., Thomas,K., Thorpe,A., Timms,K., Tracey,A.,
            Trevanion,S., Tromans,A.C., d'Urso,M., Verduzco,D., Villasana,D.,
            Waldron,L., Wall,M., Wang,Q., Warren,J., Warry,G.L., Wei,X.,
            West,A., Whitehead,S.L., Whiteley,M.N., Wilkinson,J.E.,
            Willey,D.L., Williams,G., Williams,L., Williamson,A.,
            Williamson,H., Wilming,L., Woodmansey,R.L., Wray,P.W., Yen,J.,
            Zhang,J., Zhou,J., Zoghbi,H., Zorilla,S., Buck,D., Reinhardt,R.,
            Poustka,A., Rosenthal,A., Lehrach,H., Meindl,A., Minx,P.J.,
            Hillier,L.W., Willard,H.F., Wilson,R.K., Waterston,R.H., Rice,C.M.,
            Vaudin,M., Coulson,A., Nelson,D.L., Weinstock,G., Sulston,J.E.,
            Durbin,R., Hubbard,T., Gibbs,R.A., Beck,S., Rogers,J. and
            Bentley,D.R.
  TITLE     The DNA sequence of the human X chromosome
  JOURNAL   Nature 434 (7031), 325-337 (2005)
   PUBMED   15772651
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC035026.2, AL043092.2 and AL043093.3.
            This sequence is a reference standard in the RefSeqGene project.
            
            On May 17, 2019 this sequence version replaced NM_152631.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC035026.2, AK093101.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000329357.6/ ENSP00000328307.5
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-641               BC035026.2         1-641
            642-1186            AL043092.2         73-617
            1187-1996           BC035026.2         1187-1996
            1997-2120           AL043093.3         39-162              c
FEATURES             Location/Qualifiers
     source          1..2120
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xp21.1"
     gene            1..2120
                     /gene="FAM47B"
                     /note="family with sequence similarity 47 member B"
                     /db_xref="GeneID:170062"
                     /db_xref="HGNC:HGNC:26659"
     exon            1..2120
                     /gene="FAM47B"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..1974
                     /gene="FAM47B"
                     /codon_start=1
                     /product="protein FAM47B"
                     /protein_id="NP_689844.2"
                     /db_xref="CCDS:CCDS14236.1"
                     /db_xref="GeneID:170062"
                     /db_xref="HGNC:HGNC:26659"
                     /translation="MGDRRPQDRPRSQGMDSKPWYCDKPPSKYFAKRKHRRLRFPPVD
                     TQNWVFVTEGMDDFRYACQSPEDTLVCRRDEFLLPKISLRGPQADRKSRKKKLLKKAA
                     LFSELSPVQPARKAFVEEVEAQLMTKHPLAMYPNLGKDMPPDLLLQVLKQLDPERKLE
                     DAWARCEAREKTTEVPTESGKYPCGESCPRPPETPVSRLRPQLPKTPVSSRRPEPPKT
                     RVSSLRPEPPKTRVSSLHPEPPETRASHLRVDPPETGVSHLCPEPPKTLVSSVHPEPP
                     DTGASHLCPEPPETRVSHLHPEPPETGVSHLRPEPSKTQVSSLCPEPPEAGVSHLCLE
                     PPNTHRVSSFLLQVLKLDSEKKLEDARARCEGQEMTTEELTKPGKYHFWESCPRPFES
                     RMPHLRLVLPITRRMASLCLKPPKTRRVSSLCPEPTKTGASHLKELFQEDTPSTMECV
                     SDSLQRRHTSRKLRDFKWAGDLGVNEESISSLFDFTPECRTTDQDQKIKKANECASRL
                     MYGMELDDMDEVEFLRIKYWDRRRRAAPHSYSAQRGRIRYGPWYFEPKLGKKLRSDEP
                     LIDPKPVLEKPDEPDILDGLYGPIAFKDFILSKGYRMPGVIEKLFAKKGWTYDSVKTP
                     IQRAVQVYKYKEDVTDASKED"
     regulatory      2102..2107
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM47B"
                     /note="hexamer: TATAAA"
     polyA_site      2120
                     /gene="FAM47B"
                     /note="major polyA site"
ORIGIN      
        1 agaagctgga gaggtggcac aacagagagg gccaccatgg gggaccggag gccacaggac
       61 cggccaaggt cccaaggcat ggactccaag ccctggtact gtgacaaacc gccttccaag
      121 tacttcgcga agcgcaagca caggcgcctg aggttcccgc ctgtggacac ccagaactgg
      181 gtatttgtga cggagggcat ggacgacttc cgctacgcct gtcagtctcc tgaagatacg
      241 cttgtttgtc gccgtgacga gtttttactc cccaaaatat ctctcagagg tccccaagct
      301 gaccgcaaaa gcaggaagaa aaagctgctc aagaaagcgg ccctattttc cgagctctcg
      361 ccagtacagc cagcacggaa ggcgttcgta gaggaagtgg aagcccagct gatgaccaag
      421 catcccttgg ccatgtaccc caatctggga aaagatatgc ctccagatct cctactacag
      481 gtgctgaaac agctggatcc cgagaggaag ctggaggacg cttgggctcg ttgtgaggcc
      541 cgggagaaga caaccgaggt acccaccgag tctggtaaat atccctgtgg ggaatcctgc
      601 ccgcggcctc ccgagactcc ggtgtcccgt ctccgtcctc agcttcccaa gactccggtg
      661 tccagtcgcc gcccagagcc tcccaagact cgggtgtcca gtctccgccc agagcctccc
      721 aagactcggg tgtccagtct ccacccggaa cctccagaga ctcgcgcatc tcatctccgc
      781 gtggatcctc ccgagactgg agtgtcccat ctctgcccag agcctcccaa gactctggtg
      841 tccagtgtcc acccagagcc tcctgatact ggagcgtccc atctctgccc ggagcctccc
      901 gagactcgcg tatctcatct ccacccggag cctcctgaga ctggagtgtc ccatctccgc
      961 ccagagcctt ccaagactca ggtgtccagt ctctgcccgg agcctcccga ggctggagtg
     1021 tcccatctct gcctggaacc tcccaacact catcgggtgt ccagtttcct actacaggtg
     1081 ctgaaactgg attctgagaa gaagctggaa gacgcacggg ctcgttgtga gggccaggag
     1141 atgacaaccg aggaactcac caagcctggt aaataccatt tttgggaatc ctgtccgcgg
     1201 ccttttgaga gtcggatgcc ccatctccgc ctggtgcttc ccataactcg tcgaatggcc
     1261 agtctctgcc tgaagcctcc caagactcgt cgggtgtcca gtctctgccc ggagcctacc
     1321 aagaccggag cgtcccatct aaaagaactg tttcaggaag atacaccaag cacaatggag
     1381 tgtgtttctg actctcttca acgtagacac acatcgagaa aactccgtga cttcaagtgg
     1441 gctggagacc taggagttaa tgaagaatcc atcagcagtc tgtttgactt tacccctgag
     1501 tgcagaacaa ccgatcaaga ccaaaagatt aagaaggcaa acgagtgtgc ttcaaggctg
     1561 atgtacggca tggagctaga cgacatggat gaggtcgaat tcttacggat aaaatactgg
     1621 gacaggagac gccgggcggc accgcattct tatagtgcac agcgtgggag gataaggtat
     1681 ggaccatggt acttcgagcc taagttgggg aaaaagctaa gaagtgatga acctttgatt
     1741 gaccccaagc ccgtacttga aaagcctgat gaacccgaca ttcttgacgg tctttatgga
     1801 ccaattgcct ttaaggattt cattctaagc aagggctaca gaatgcctgg cgtcattgaa
     1861 aagctgtttg ccaagaaggg atggacttac gactctgtta agactcctat tcaacgtgca
     1921 gtgcaagttt acaagtacaa agaagacgtc acagatgcat caaaagaaga ttagatggtt
     1981 ttcaatttac tgcttaattg ggtatttctt gctctcattc taaacatcaa tcagaattta
     2041 tgatgactgg ccccgtgaat gtacaacttt ggcaacatct gtaaattcaa tacccaatgc
     2101 ttataaatat gtcttaatga
//
