LOCUS       NM_153690               3155 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens family with sequence similarity 43 member A (FAM43A),
            mRNA.
ACCESSION   NM_153690
VERSION     NM_153690.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3155)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 3155)
  AUTHORS   Wan,D., Gong,Y., Qin,W., Zhang,P., Li,J., Wei,L., Zhou,X., Li,H.,
            Qiu,X., Zhong,F., He,L., Yu,J., Yao,G., Jiang,H., Qian,L., Yu,Y.,
            Shu,H., Chen,X., Xu,H., Guo,M., Pan,Z., Chen,Y., Ge,C., Yang,S. and
            Gu,J.
  TITLE     Large-scale cDNA transfection screening for genes related to cancer
            development and progression
  JOURNAL   Proc Natl Acad Sci U S A 101 (44), 15724-15729 (2004)
   PUBMED   15498874
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 Dec 14:101(50):17565]
REFERENCE   3  (bases 1 to 3155)
  AUTHORS   Robertson,N.G., Khetarpal,U., Gutierrez-Espeleta,G.A., Bieber,F.R.
            and Morton,C.C.
  TITLE     Isolation of novel and known genes from a human fetal cochlear cDNA
            library using subtractive hybridization and differential screening
  JOURNAL   Genomics 23 (1), 42-50 (1994)
   PUBMED   7829101
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC046143.20, BM561125.1, AF147314.1, BG107959.1, BC039689.2,
            BG110772.1, BQ009970.1 and BI494721.1.
            
            On May 17, 2019 this sequence version replaced NM_153690.4.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC064989.1, SRR1163657.317082.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000329759.6/ ENSP00000371397.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                AC046143.20        171888-171897
            11-616              BM561125.1         1-606
            617-781             AF147314.1         181-345
            782-801             BG107959.1         81-100
            802-2092            BC039689.2         1-1291
            2093-2232           BG110772.1         423-562
            2233-2661           BC039689.2         1432-1860
            2662-3093           BQ009970.1         18-449              c
            3094-3155           BI494721.1         293-354
FEATURES             Location/Qualifiers
     source          1..3155
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q29"
     gene            1..3155
                     /gene="FAM43A"
                     /note="family with sequence similarity 43 member A"
                     /db_xref="GeneID:131583"
                     /db_xref="HGNC:HGNC:26888"
     exon            1..3155
                     /gene="FAM43A"
                     /inference="alignment:Splign:2.1.0"
     CDS             945..2216
                     /gene="FAM43A"
                     /codon_start=1
                     /product="protein FAM43A"
                     /protein_id="NP_710157.2"
                     /db_xref="CCDS:CCDS33923.1"
                     /db_xref="GeneID:131583"
                     /db_xref="HGNC:HGNC:26888"
                     /translation="MLPWKKHKFELLAEAPPRQASKPKGYAVSLHYSALSSLARACPE
                     GALSRVGSMFRSKRKKLHITSEDPTYTVLYLGNATTIQARGDGCTDLAVGKIWSKSEA
                     GRQGTKMKLTVSAQGIRMVHAEERALRRPGHLYLLHRVTYCVADARLPKVFAWVYRHE
                     LKHKAVMLRCHAVLVSKPEKAQAMALLLYQTSANALAEFKRLKRRDDARHQQQELVGA
                     HTIPLVPLRKLLLHGPCCYKPPVERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPE
                     GCPEEEENRAAEGDPAEEEAEAQRALVVAMHFECGDLLDTLENGRGEALGGGGGSLGP
                     GAGPPPLLLGSASDMKAELSQLISDLGELSFGNDVRTLQADLRVTRLLSGDSTGSESS
                     IEGGGPDATSATAGDSSRQADGASADEPHSG"
     regulatory      3064..3069
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM43A"
                     /note="hexamer: TATAAA"
     polyA_site      3090
                     /gene="FAM43A"
                     /note="major polyA site"
     regulatory      3132..3137
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM43A"
                     /note="hexamer: AATAAA"
     polyA_site      3155
                     /gene="FAM43A"
ORIGIN      
        1 aaggatgtga ggcaggcgag ccggacgccg ctcgcagcac cggagagggc gcactgcaaa
       61 ggcgggcagc agaccgtgga gagcccggga gcggagctgg acaccgcctc ggagggaaga
      121 aatgaggtag cggcggttcc cggacccggc catgcccgtc ccctgttctc ggagcccagc
      181 gccgtctcgg ccaggccagc ccggacactg agcgggccga gcgcgagtcc ccggcgtccg
      241 gcggagcgaa gatgcagtga gtccccgcgg gactgctgcg cggggcccgc cgcggccagc
      301 cggacccagc atccgaccgc actttgggcg agctgctgac ttgagaccag cccaaacggg
      361 gggctttcca tctccagcac ccctcggagg tggggagcac cggcccctag gcacactcgc
      421 tgtagagttt ccgcgggttt tggccccagt cctgagggtt gtgtgtgtta ggggacccac
      481 ctcacgttcg ccgaggagtt cctgcatatt cttgcaccat cccgggtgct gttgctgggg
      541 ctctctttat ttgcacgcgc gcttctagct tttttcctga cattttccac tctacgctcg
      601 ttctttctcc cttgcatttt gttgcttgcc tgagactctt tgctctcgcc cttgcccagg
      661 ctggggtaat tctgtgtgcg cgcgtgtctc ccccgcacca accttttttg cacactcgaa
      721 gctgaatatt ttctttttta gagaatttac ccgcacctcc tgcggggttc ctaagcactc
      781 tctctgctcc cctcccccca actccctacc acagggccgc tcccagtagt tttattcttc
      841 gatcttgccc gggccgagcc tggcaggggc cggtggctca gcgggcctcg cacccggcgc
      901 tccgccgccg ccgccgccca gctgcgccgg ggcgccctcc ggagatgctg ccgtggaaga
      961 agcacaagtt cgagctgctg gccgaggcgc cgccgcggca ggcgtccaag cccaagggct
     1021 acgctgtgag cctgcactac tcggcgctca gctcgctggc gcgggcgtgc cccgaaggcg
     1081 cgcttagccg ggtgggcagc atgttccgct ccaagcgcaa gaagctgcac atcactagcg
     1141 aggacccaac ttacaccgtg ctctacctgg gcaatgccac caccatccag gcgcgcggcg
     1201 acggctgcac cgaccttgct gtgggcaaga tctggagcaa gagcgaggcg ggccgtcagg
     1261 gcaccaagat gaagctgacg gtgagtgcgc agggtatccg catggtgcac gccgaggagc
     1321 gcgcgctgcg ccgcccgggc cacctctacc tgctgcaccg cgtcacctac tgcgtggccg
     1381 acgcgcggct gcccaaggtc ttcgcctggg tgtaccggca cgagctgaag cacaaggccg
     1441 tgatgctgcg ctgccacgcc gtgctggtgt ccaagcccga aaaggcgcag gccatggccc
     1501 tgctgctcta ccagacgtcg gccaacgcgc tggcggaatt taaacgcctc aagcggcggg
     1561 acgacgcgcg tcaccagcag caggagctgg tgggcgcaca caccatcccg ctagtgccgc
     1621 tgcgcaagct gctcctacac ggaccctgct gctataaacc gccggtggag cgcagccgca
     1681 gcgcgcccaa gcttggctcc atcaccgagg acctgctcgg cgaacagctg gagcaggagc
     1741 tgcaggagga agaggaagag gagcaacccg agggctgccc ggaggaggag gagaaccgtg
     1801 cggcagaggg agatccagca gaggaggagg ccgaggcgca gcgtgcgcta gtggtcgcca
     1861 tgcactttga gtgcggggac ttgttggata ctctggagaa tggccgtggg gaggcgctag
     1921 gaggcggcgg gggctccctg ggcccggggg ccgggccgcc gcctctgctg ctgggcagcg
     1981 cctccgacat gaaggctgag ctgtcgcaac ttattagcga cctgggcgag ctcagcttcg
     2041 gcaacgacgt gcgcaccctg caggccgact tgcgggtgac gcgcctgctg tcaggcgaca
     2101 gcacgggcag cgagagctcc atcgagggcg ggggccctga cgccacctcc gccaccgccg
     2161 gggactcgtc ccgccaggcc gacggcgcca gtgcagacga gccccactcg ggctgagctc
     2221 ctccgcgcgt cgccggcgct ccaccgtggc tacccatccg tggtcccgac aacctccctg
     2281 tcccttgccc gcccccagga agggggaaat ggggcatttg gggcccagac ctacacttgg
     2341 agcccaggtc cagcgttccc ccgaccgctt tcccctacct cccggccccc gctcccgccc
     2401 cagcactttt ggctctgttg cgcgtgggga tgcggggaga tttgagaggg gaaaaccccg
     2461 ccaggaggga gagagaggca cccctctggg atgcgggtga gggaaggttg gctgaagttc
     2521 ctagtctcag gccgtaggtg cctggccagt ttcctgtttg tggggcagct ggggcctgag
     2581 gaggaggggt tcacttcctc ctcccacccc ctgggagcgg ccctgcgctg tcactgacat
     2641 ctcattaaaa aaaaaaaaaa atttgctctc aaggtgtttg aggctttaat gcaacccttt
     2701 agcccttggt tctttttggt gcaagaattc tggctgttta cctcagactc agacccctga
     2761 aatgttgcca aattcttcaa ataactgttt ggggggtggg gggagatgaa agagagtcgc
     2821 gttttgttta cagttaaaga catccaatat cttaaaaagg agttttcctt tagaaacaca
     2881 cacacccttc ctcttgctca aaagatctca ctccatgata ctgtgtaaaa tatttttgca
     2941 ctgttgtgaa gtatttttga cttttttctg tacataactg tgttctcaga gctgaatgtt
     3001 tatatctttt gctgtgcaaa agaaacatgt aaaatgttgt tcagttgtat atacagaaat
     3061 gtgtataaaa cattttgtta ttttttaaaa gtagcactgt tctggttctg tttgcacgcc
     3121 agtggggaga gaataaagag gaaaatttaa cagaa
//
