LOCUS       NM_001146157             357 bp    mRNA    linear   PRI 18-NOV-2024
DEFINITION  Homo sapiens family with sequence similarity 25 member A (FAM25A),
            mRNA.
ACCESSION   NM_001146157 XM_001723781 XM_002343005 XM_926530 XM_937048
VERSION     NM_001146157.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 357)
  AUTHORS   Deloukas,P., Earthrowl,M.E., Grafham,D.V., Rubenfield,M.,
            French,L., Steward,C.A., Sims,S.K., Jones,M.C., Searle,S.,
            Scott,C., Howe,K., Hunt,S.E., Andrews,T.D., Gilbert,J.G.,
            Swarbreck,D., Ashurst,J.L., Taylor,A., Battles,J., Bird,C.P.,
            Ainscough,R., Almeida,J.P., Ashwell,R.I., Ambrose,K.D.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Bates,K.,
            Beasley,H., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.C.,
            Burrill,W., Burton,J., Cahill,P., Camire,D., Carter,N.P.,
            Chapman,J.C., Clark,S.Y., Clarke,G., Clee,C.M., Clegg,S., Corby,N.,
            Coulson,A., Dhami,P., Dutta,I., Dunn,M., Faulkner,L., Frankish,A.,
            Frankland,J.A., Garner,P., Garnett,J., Gribble,S., Griffiths,C.,
            Grocock,R., Gustafson,E., Hammond,S., Harley,J.L., Hart,E.,
            Heath,P.D., Ho,T.P., Hopkins,B., Horne,J., Howden,P.J., Huckle,E.,
            Hynds,C., Johnson,C., Johnson,D., Kana,A., Kay,M., Kimberley,A.M.,
            Kershaw,J.K., Kokkinaki,M., Laird,G.K., Lawlor,S., Lee,H.M.,
            Leongamornlert,D.A., Laird,G., Lloyd,C., Lloyd,D.M., Loveland,J.,
            Lovell,J., McLaren,S., McLay,K.E., McMurray,A.,
            Mashreghi-Mohammadi,M., Matthews,L., Milne,S., Nickerson,T.,
            Nguyen,M., Overton-Larty,E., Palmer,S.A., Pearce,A.V., Peck,A.I.,
            Pelan,S., Phillimore,B., Porter,K., Rice,C.M., Rogosin,A.,
            Ross,M.T., Sarafidou,T., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
            Smith,M., Standring,L., Sycamore,N., Tester,J., Thorpe,A.,
            Torcasso,W., Tracey,A., Tromans,A., Tsolas,J., Wall,M., Walsh,J.,
            Wang,H., Weinstock,K., West,A.P., Willey,D.L., Whitehead,S.L.,
            Wilming,L., Wray,P.W., Young,L., Chen,Y., Lovering,R.C.,
            Moschonas,N.K., Siebert,R., Fechtel,K., Bentley,D., Durbin,R.,
            Hubbard,T., Doucette-Stamm,L., Beck,S., Smith,D.R. and Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 10
  JOURNAL   Nature 429 (6990), 375-381 (2004)
   PUBMED   15164054
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL136982.11.
            
            On Nov 22, 2018 this sequence version replaced NM_001146157.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BQ013919.1, BC171878.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2145893, SAMEA2147596
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000343959.5/ ENSP00000342790.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-104               AL136982.11        54427-54530
            105-167             AL136982.11        56447-56509
            168-357             AL136982.11        58674-58863
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q23.2"
     gene            1..357
                     /gene="FAM25A"
                     /gene_synonym="bA96C23.5"
                     /note="family with sequence similarity 25 member A"
                     /db_xref="GeneID:643161"
                     /db_xref="HGNC:HGNC:23436"
     exon            1..104
                     /gene="FAM25A"
                     /gene_synonym="bA96C23.5"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..301
                     /gene="FAM25A"
                     /gene_synonym="bA96C23.5"
                     /note="protein FAM25; Protein FAM25C; Protein FAM25G"
                     /codon_start=1
                     /product="protein FAM25A"
                     /protein_id="NP_001139629.1"
                     /db_xref="CCDS:CCDS44451.1"
                     /db_xref="GeneID:643161"
                     /db_xref="HGNC:HGNC:23436"
                     /translation="MLGGLGKLAAEGLAHRTEKATEGAIHAVEEVVKEVVGHAKETGE
                     KAIAEAIKKAQESGDKKMKEITETVTNTVTNAITHAAESLDKLGQ"
     exon            105..167
                     /gene="FAM25A"
                     /gene_synonym="bA96C23.5"
                     /inference="alignment:Splign:2.1.0"
     exon            168..357
                     /gene="FAM25A"
                     /gene_synonym="bA96C23.5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      335..340
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM25A"
                     /gene_synonym="bA96C23.5"
                     /note="hexamer: AATAAA"
     polyA_site      357
                     /gene="FAM25A"
                     /gene_synonym="bA96C23.5"
                     /note="major polyA site"
ORIGIN      
        1 atcctagttc accactgtct gctgccacac gatgctggga ggcctgggga agctggctgc
       61 cgaaggcctg gcccaccgca ccgagaaggc caccgaggga gccattcatg ccgtggaaga
      121 agtggtgaag gaggtggtgg gacacgccaa ggagactgga gagaaagcca ttgctgaagc
      181 cataaagaaa gcccaagagt caggggacaa aaagatgaag gaaatcactg agacagtgac
      241 caacacagtc acaaatgcca tcacccatgc agcagagagt ctggacaaac ttggacagtg
      301 agtgcacctg ctaccacggc ccttccccag tctcaataaa aagccatgac atgtgta
//
