LOCUS       NM_152644                728 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens family with sequence similarity 24 member B (FAM24B),
            transcript variant 1, mRNA.
ACCESSION   NM_152644 XM_001131369
VERSION     NM_152644.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 728)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 728)
  AUTHORS   Clark,H.F., Gurney,A.L., Abaya,E., Baker,K., Baldwin,D., Brush,J.,
            Chen,J., Chow,B., Chui,C., Crowley,C., Currell,B., Deuel,B.,
            Dowd,P., Eaton,D., Foster,J., Grimaldi,C., Gu,Q., Hass,P.E.,
            Heldens,S., Huang,A., Kim,H.S., Klimowski,L., Jin,Y., Johnson,S.,
            Lee,J., Lewis,L., Liao,D., Mark,M., Robbie,E., Sanchez,C.,
            Schoenfeld,J., Seshagiri,S., Simmons,L., Singh,J., Smith,V.,
            Stinson,J., Vagts,A., Vandlen,R., Watanabe,C., Wieand,D., Woods,K.,
            Xie,M.H., Yansura,D., Yi,S., Yu,G., Yuan,J., Zhang,M., Zhang,Z.,
            Goddard,A., Wood,W.I., Godowski,P. and Gray,A.
  TITLE     The secreted protein discovery initiative (SPDI), a large-scale
            effort to identify novel human secreted and transmembrane proteins:
            a bioinformatics assessment
  JOURNAL   Genome Res 13 (10), 2265-2270 (2003)
   PUBMED   12975309
  REMARK    Erratum:[Genome Res. 2003 Dec;13(12):2759]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB410280.1, BG490871.1, AV762334.2, BC031343.1 and AC073585.8.
            
            On Nov 23, 2018 this sequence version replaced NM_152644.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the supported protein. Both variants 1 and 2
            encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AV762334.2, SRR1803614.244408.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2146236, SAMEA2150385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000368898.8/ ENSP00000357894.3
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 CB410280.1         62-65
            5-239               BG490871.1         30-264
            240-326             AV762334.2         240-326
            327-712             BC031343.1         308-693
            713-728             AC073585.8         189293-189308
FEATURES             Location/Qualifiers
     source          1..728
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q26.13"
     gene            1..728
                     /gene="FAM24B"
                     /note="family with sequence similarity 24 member B"
                     /db_xref="GeneID:196792"
                     /db_xref="HGNC:HGNC:23475"
     exon            1..97
                     /gene="FAM24B"
                     /inference="alignment:Splign:2.1.0"
     exon            98..239
                     /gene="FAM24B"
                     /inference="alignment:Splign:2.1.0"
     exon            240..366
                     /gene="FAM24B"
                     /inference="alignment:Splign:2.1.0"
     CDS             275..559
                     /gene="FAM24B"
                     /note="protein FAM24B"
                     /codon_start=1
                     /product="protein FAM24B precursor"
                     /protein_id="NP_689857.2"
                     /db_xref="CCDS:CCDS31303.1"
                     /db_xref="GeneID:196792"
                     /db_xref="HGNC:HGNC:23475"
                     /translation="MPVIAGGILAALLLLIVVVLCLYFKIHNALKAAKEPEAVAVKNH
                     NPDKVWWAKNSQAKTIATESCPALQCCEGYRMCASFDSLPPCCCDINEGL"
     exon            367..728
                     /gene="FAM24B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      688..693
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM24B"
                     /note="hexamer: AATAAA"
     regulatory      708..713
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM24B"
                     /note="hexamer: AATAAT"
     polyA_site      712
                     /gene="FAM24B"
                     /note="major polyA site"
     polyA_site      728
                     /gene="FAM24B"
ORIGIN      
        1 actgtgcgcg ggcaccacgg cggtttttcg acgctggcgg tggacgcagg cagcatggac
       61 cacggttgct gggcggatgg ggagcgtcta tggtcagttg ccttagaagt ggtgagatgg
      121 gaagctgcag ttggaagacc ctggaggatg cctgacaagg ggatgtctga cacatgattg
      181 gagctctttt tgaaatgttt cttgcccttc ctggagcaga ggagccatta tttatgcagg
      241 tacatcgaag tcttttgacc tccatacagt gattatgcct gtcatcgctg gtggtatcct
      301 ggcggccttg ctcctgctga tagttgtcgt gctctgtctt tacttcaaaa tacacaacgc
      361 gctaaaagct gcaaaggaac ctgaagctgt ggctgtaaaa aatcacaacc cagacaaggt
      421 gtggtgggcc aagaacagcc aggccaaaac cattgccacg gagtcttgtc ctgccctgca
      481 gtgctgtgaa ggatatagaa tgtgtgccag ttttgattcc ctgccacctt gctgttgcga
      541 cataaatgag ggcctctgag ttaggaaagg tgggcacaaa aatcttcatg agcaatactt
      601 cttagtagat tgttttgtta ttcaaatcaa gttctagtgt ttttatgtga gattatataa
      661 tttacagtgt tgttttatat acttttgaat aaatgtacac tattaaaaat aatcctcttt
      721 gctgccaa
//
