LOCUS       NM_001195442            1736 bp    mRNA    linear   PRI 06-OCT-2024
DEFINITION  Homo sapiens family with sequence similarity 240 member A
            (FAM240A), mRNA.
ACCESSION   NM_001195442 XR_042322 XR_042427 XR_042465
VERSION     NM_001195442.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1736)
  AUTHORS   Chouraki,V., De Bruijn,R.F., Chapuis,J., Bis,J.C., Reitz,C.,
            Schraen,S., Ibrahim-Verbaas,C.A., Grenier-Boley,B., Delay,C.,
            Rogers,R., Demiautte,F., Mounier,A., Fitzpatrick,A.L., Berr,C.,
            Dartigues,J.F., Uitterlinden,A.G., Hofman,A., Breteler,M.,
            Becker,J.T., Lathrop,M., Schupf,N., Alperovitch,A., Mayeux,R., van
            Duijn,C.M., Buee,L., Amouyel,P., Lopez,O.L., Ikram,M.A., Tzourio,C.
            and Lambert,J.C.
  CONSRTM   Alzheimer's Disease Neuroimaging Initiative
  TITLE     A genome-wide association meta-analysis of plasma Abeta peptides
            concentrations in the elderly
  JOURNAL   Mol Psychiatry 19 (12), 1326-1335 (2014)
   PUBMED   24535457
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK130758.1 and AC104304.2.
            
            On Sep 28, 2018 this sequence version replaced NM_001195442.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK130758.1, SRR1803616.270885.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968832, SAMEA2145240
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000640551.3/
                                                ENSP00000491838.2
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-238               AK130758.1         91-328
            239-239             AC104304.2         149589-149589
            240-495             AK130758.1         330-585
            496-1680            AC104304.2         157645-158829
            1681-1736           AK130758.1         1773-1828
FEATURES             Location/Qualifiers
     source          1..1736
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p21.31"
     gene            1..1736
                     /gene="FAM240A"
                     /note="family with sequence similarity 240 member A"
                     /db_xref="GeneID:100132146"
                     /db_xref="HGNC:HGNC:52390"
     exon            1..174
                     /gene="FAM240A"
                     /inference="alignment:Splign:2.1.0"
     CDS             160..411
                     /gene="FAM240A"
                     /codon_start=1
                     /product="protein FAM240A"
                     /protein_id="NP_001182371.2"
                     /db_xref="CCDS:CCDS82764.2"
                     /db_xref="GeneID:100132146"
                     /db_xref="HGNC:HGNC:52390"
                     /translation="MRLFSGMNNQYTRREVFCRNTCHDLKHFWEREIGKQTYYRESEE
                     RRLGRSALRKLREEWKQRLETKLRLRNNPEDTEKRTNVG"
     exon            175..320
                     /gene="FAM240A"
                     /inference="alignment:Splign:2.1.0"
     exon            321..1736
                     /gene="FAM240A"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaattgctgg cacagcgtta aggcttgcga gggacaaatg ttcctttgtt cttgttgatt
       61 tgctgaacgt gaattggctc ctggggcagc acagatgcct cacaggcggt caagtgcgac
      121 acatttggtt cgactgaatc gatgtcttca catcccttca tgcggttgtt ctctgggatg
      181 aacaatcaat acacccgtcg ggaggtcttc tgccggaaca cctgccatga tctcaagcat
      241 ttctgggaaa gggaaattgg caaacagact tactaccgag aatcagagga acgtcgtctg
      301 ggaagaagcg cactgagaaa gctcagagaa gaatggaagc agaggctgga aacaaagctg
      361 aggctgcgga acaatccaga ggacactgaa aagaggacaa atgttggctg agagcttcct
      421 gcttcattga cacaagaaga tgcaaaacac tgaggtcact ttgctagaag tcagtgcaaa
      481 ttcctgagtc cctttgctat accaatcagc tctcacacta ttgtttcccc acctgggaga
      541 ggacttacct gtaaatcctt tcccagtgtt tgatggcagt tattggccaa gtcagtcctc
      601 tgtgcatggg cgccaggtta ttatcccaaa tgtctctaaa gatagcttat ttaatatcga
      661 agctccatgc agcattcctt gcttctatat aattatcttc taattttgaa atccaaatat
      721 tttaaactct aaacacacca agaggaatcc tcaaccttca tggtcaaact ttaaacactg
      781 tacagtggta ttgccccacc atttcaccta ggaaacacag ctttatggaa ttcttgtttt
      841 ctttttatga gaagagaaat gcacctatct gcagaaatta aaaaacaatt atcaatagtc
      901 aaagtacaat ttgaaaataa attgatctaa tattcttttt tcttcatata aatttaatta
      961 gctttttcaa aagtatgttt accaagaata atatcagaat aattttaata aaacttggtt
     1021 gtcctgtcat cactatgcac atgccttcat tttattgctt tattttaatc tctgcatgtt
     1081 tacactggtt ggctctctgt cagcccagcc aaagcatatc tggccattcc acagagtgtt
     1141 taccacacag attctggatt ttgaaatggt atagtcactc ccttgccatc tctcaagttc
     1201 agaagcacca gggtttgatg cttccaagag tgcaaactgt aactgggcct gaggcaatta
     1261 ttttaaccaa gggaagggag aagagatgca atgatataaa gtcctgggta cttgctggct
     1321 gtaagcagca cctgcaaggc cttatatact atacacagag gcactgtatg gcagacgcac
     1381 ctgacagcaa taacaagata ataagttaag caaatacact gagaatgaca ttatggtcta
     1441 agaagaatgt gtgttcggag tcccaagcta aggaatccgg gagtggccaa ccgggagttt
     1501 cataccttaa ttgtgaagga cacctgaacc cccagccatc ctttggaaca taggttgtac
     1561 aggggatcaa agccttctgt tttgggttag atggtggttg ctaggtggag ggtgctaagt
     1621 gaaaatgcta tataaactgc atgcttttta caaacagtag tggttctctt gtccagccca
     1681 ctgctactgg accatcccta tgtaagttcc cccaataaac cctatgtctc attcac
//
