LOCUS       NM_020853               4711 bp    mRNA    linear   PRI 06-OCT-2024
DEFINITION  Homo sapiens family with sequence similarity 234 member B
            (FAM234B), mRNA.
ACCESSION   NM_020853 XM_370682
VERSION     NM_020853.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4711)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 4711)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC023790.21.
            
            On Aug 25, 2018 this sequence version replaced NM_020853.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC039267.1, SRR1803614.56413.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968832
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000197268.13/ ENSP00000197268.8
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-60                AC023790.21        53944-54003         c
            61-456              AC023790.21        42438-42833         c
            457-555             AC023790.21        39835-39933         c
            556-744             AC023790.21        36621-36809         c
            745-875             AC023790.21        35409-35539         c
            876-1023            AC023790.21        31597-31744         c
            1024-1165           AC023790.21        31088-31229         c
            1166-1309           AC023790.21        29937-30080         c
            1310-1391           AC023790.21        29673-29754         c
            1392-1547           AC023790.21        26988-27143         c
            1548-1665           AC023790.21        22241-22358         c
            1666-1886           AC023790.21        18375-18595         c
            1887-4711           AC023790.21        14935-17759         c
FEATURES             Location/Qualifiers
     source          1..4711
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12p13.1"
     gene            1..4711
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /note="family with sequence similarity 234 member B"
                     /db_xref="GeneID:57613"
                     /db_xref="HGNC:HGNC:29288"
                     /db_xref="MIM:617838"
     exon            1..60
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /inference="alignment:Splign:2.1.0"
     CDS             24..1892
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /codon_start=1
                     /product="protein FAM234B"
                     /protein_id="NP_065904.1"
                     /db_xref="CCDS:CCDS31750.1"
                     /db_xref="GeneID:57613"
                     /db_xref="HGNC:HGNC:29288"
                     /db_xref="MIM:617838"
                     /translation="MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQKN
                     GGVKNGKSPLGEAPEPDSDAEVAEAAKPHLSEVTTEGYPSEPLGGLEQKAASSLVSYV
                     RTSVFLLTLGISMILVLLCAFLIPCPPRDLHSTWSRHLGSQGGGDLSPLELADVNGDG
                     LRDVLLSFVMSRNGSAVGVSRPAANLVCLSGMNGSTLWSSLLPEEARDITCLELMPGS
                     LAETICLVTGTHKMLSAFNATSGKAIWTLNPNYLSNGTLAAPVVVLPDLDEDGVRDLV
                     VLAIGELQPDLCFLLVSGRTGNPVGRPVKYNIVGVGNLIGPQVYITTNGAVYILFGFG
                     NIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKRRSINLSELIDVYSDGVELLQMVKA
                     PDSNCSNLLITTRQSLVLLRGQNLTPYWALRLQGLRSQPTPGYFTDDQTLDFLLQIQD
                     GVGMKKMMVVDGDSGSIVWSYRAPCHMKETPATSAVTSDQKSVFLFWAEGLSAASPNS
                     DIILGTEPPSLHHLYLLHPAFPSILLDLANTTGTVTASEVGINDLWKDAFYVTRTTGP
                     SSEGHPAALVVSKLSLRWALMEGQMAQLQESTPKIGRGELRRFLSRIKFVEAPYEI"
     exon            61..456
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            457..555
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            556..744
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            745..875
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            876..1023
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..1165
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1309
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1391
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            1392..1547
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            1548..1665
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            1666..1886
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /inference="alignment:Splign:2.1.0"
     exon            1887..4711
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4693..4698
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /note="hexamer: AATAAA"
     polyA_site      4711
                     /gene="FAM234B"
                     /gene_synonym="KIAA1467"
                     /note="major polyA site"
ORIGIN      
        1 gcacgcgcac cggggcctca gccatggcga ccgtgctgtc cagggcgctc aagctgccgg
       61 ggaagaagag cccagaccta ggggagtatg atccacttac ccaggctgac agtgatgaga
      121 gcgaagacga tctggtgctt aacctgcaga agaatggagg ggtcaaaaat gggaagagtc
      181 ctttgggaga agcgccagaa cccgactcag atgctgaggt tgcagaggct gcaaagccac
      241 atctttcaga agtcaccacg gagggctacc cctcagaacc ccttgggggc ctggaacaga
      301 aggcggcctc ctccctggtg tcatatgtgc gcacgtctgt cttcctgctg actttgggga
      361 tctcgatgat cctggtgctc ctgtgtgctt tcctgatccc ctgtcctccc agagatctgc
      421 acagcacctg gagccgccac ttgggctccc agggaggtgg ggacctgtct ccattggaat
      481 tggctgatgt gaatggagat ggcctgcgtg atgtgcttct ctcctttgtg atgtcaagga
      541 acgggagtgc agtaggtgtc tcaagaccag ctgctaatct tgtatgcctt tcggggatga
      601 atggcagcac actgtggtct agtcttctcc ctgaggaggc tcgagatatc acatgtttgg
      661 agctgatgcc aggaagcttg gctgaaacca tctgccttgt gacagggaca cacaagatgc
      721 tcagcgcatt caatgcaacg tcagggaaag ccatttggac tttaaaccca aactacttgt
      781 ccaacggtac cttggctgcc ccagttgtgg tactgccaga cttggatgaa gacggtgttc
      841 gagaccttgt ggttctggcc attggggaat tgcagccaga tctgtgcttt ctgctggtgt
      901 ctggccggac cggaaatcca gtgggtcgac ctgtgaagta caacatcgtt ggagttggga
      961 atctgattgg tcctcaggtt tacatcacca caaatggggc tgtctacatc ctgtttggct
     1021 ttggaaatat acaagctgtc gcactgcggg acatttttgt tcaggcccaa aatcgagaca
     1081 gctcaccacc ttctctgcag atagaagagc cagaatggga aaagcgaaga tccatcaacc
     1141 tgtctgagct cattgatgtt tacagtgatg gtgttgaact actccagatg gtgaaggcac
     1201 cagattccaa ctgcagcaac cttctgatta caaccagaca aagccttgtg ctgcttcggg
     1261 ggcaaaatct gacaccttac tgggcattga gacttcaagg cctgcgcagc cagcctactc
     1321 ctggatattt cactgatgat cagacattag atttccttct gcagatacag gatggagttg
     1381 ggatgaaaaa gatgatggtt gtggatggtg actctggctc cattgtttgg agttaccgtg
     1441 ctccgtgtca catgaaagaa acgccagcca cctcagcagt tacttcagac cagaagtctg
     1501 tcttcctctt ctgggccgaa gggctgtcag ctgcatctcc caattccgat atcatcctag
     1561 gaactgagcc gcccagcctt caccaccttt acctcctgca tcctgcgttc ccctccatcc
     1621 ttctggatct ggccaacacc accggcacag tgacggcttc agaggttgga attaacgacc
     1681 tctggaaaga tgccttttat gttaccagga caacagggcc aagctccgaa ggccatccag
     1741 cagccctggt ggtcagcaag cttagtctac ggtgggcact aatggagggc cagatggctc
     1801 agctacagga gtccaccccc aaaattggcc gtggggagct gcgaagattt ctctctagga
     1861 taaagtttgt tgaagctccc tacgagatct aatctgatgg aatcttcagt tgcagaagaa
     1921 gtgaacagag tggataccct ctctactctc ctgtcactgt aaaatcagtt ctatggagag
     1981 aagacttctt cgtcctcatt taccacctcc ctgatggttg caaaggcttg ggaaggcatg
     2041 ttggagtctt tgacggcagc atgatctatt tggctggggc atcttaccta ccttttcagt
     2101 ccctgcatta atcccctcta ggaactctgc gtggatcgtt tggaaatgtg aatctcttaa
     2161 gtatttaatt tttttggtat gtctaattta tgaagtcttg ctgggaaagc cagtgaagtc
     2221 tatgactagg aaacattttg ttgtacattg tgctgtgtgt gtgtatattt tagtgttgtg
     2281 gtgaagttat tttccaggta tgtcctaagc ttcagggatc cagtttcttg tccttctgaa
     2341 atatatctgg tttgtttggt cattttgaga cttccagatg ccctacctct gatgttgagg
     2401 gccacttatt tctctcctta ttctttccca cctgtacctt ggctacttcc aaattgtaga
     2461 cagaatgaga aagatttata gtggaagact gagttagcca tccaagcatt ttcatctctc
     2521 ttgttttata tcctatttcc ttagattttc catccatgtc tattaagtga ccacaagaat
     2581 aactatattc ctatcacaag gggagcaaga ggatgtagtc tcagtgaccc atctctgacc
     2641 aagtccacat gttgtgttat atgtggctct gatggttctg ccagtcatga tcttttttct
     2701 gtggcgacat cagaagtgta tgtttgcatg ctgtcttcaa cttagaggag aactggaagt
     2761 caggagcctt tgatgtcctt atcctgctgt atgtcttctc tgcatctttt tctatagggc
     2821 accctcctta gctcccctca ctctgttttc tcttctattc agggatatgt ttctggactt
     2881 tttcttctgc tacttgagtc caggatgcaa ccattttgtc ctgcatctct tctttcctgt
     2941 agagcctttg aagcattgta ttttgggaaa attcttctgt aaatactata acttttataa
     3001 atggttaagt tatttagaat tatctccagt gcttacttct cccttcttct gtataaatct
     3061 gctacttcaa ttaagttctc ctctaaactt ttaggtcatt gtttatatag cagaaaattc
     3121 aatgttagcg gatggaaaac tgcttcttga ataaccttga taggtcatcc ctgagtgcac
     3181 ctcaggttct ctctttacct gggcttgtat cttttttttt tttttttttt tttttttgag
     3241 acagagtttt gctcttgtcg cccaggctgg agtgcagtgg cacaatctcg gctcactgca
     3301 accttcgcct cctgggttca agcgattctc cagccttagc ctcccaagta gctgggacta
     3361 caggtgcccg ctaccatgcc tggctaattt ttttttttgt atttttagta gagacggggt
     3421 ttcaccatgt tggccaggct ggtcacgaac tcctgacctc agataatcca cctgcttctg
     3481 cctcccaaag tgctgggatt acaggcgtga gccaccatgc ccggctgggc ttgtatcttt
     3541 tagcttgtgt tagtaaaagg attctagaaa attatgaagt ccagattcaa agggatctct
     3601 gttaattacc cactgacagg cattatgacc taacaggagg ttggtagcag tagatccaag
     3661 catgcatgtt gcctggcctg tagattggcc ttatcaggtt tctgggtgcc tctgccttaa
     3721 gatcctgaag gcaaattttg tttcaacagt ttggaagtca tctgtgggtc cagcttgact
     3781 ttggaggaat aagaagatac ttctagagta tgggaatgat tccagataat ttctgggatt
     3841 tgaatctact tgagtttaag ggcctgggac ctaatttggt ttagtataga atttgaagaa
     3901 ttaatttata ggcagctgaa tacccaaaac ttgggtggtg gtcctgtggt ttggctgagc
     3961 tgtccgggca taacctggtt ctctgttatg ttaaggcttt ctgggaagcc agccactctg
     4021 cgcaggagtg aaacatgaag ttgttttctg aggacctgtt ttggtgggat tgtttgggca
     4081 gaggactgtg tttatgcagg gcaaatccca gaaagataag aggaagctag agaaacttaa
     4141 tgtacctgaa ttcttcatgg tgtatttgca aactaactta acatagattc ttttgactat
     4201 ggtaagtttg aatctctcct tgccaaacaa cattataagt ttagttttct tcttcctctt
     4261 gcagccggta cagaaaggtg taagtggtgg ctgaaaattg aggaagcttc atctgaccaa
     4321 tgtgggtgct ggtttcttgt gaaatgtgtc cctaagcctc cttctccttg caggcagcca
     4381 cccacccagg tgtctaagat aggacatgct cctttctttc tctaatccca tcctgaggtt
     4441 gccggcaaag ccaatatgac cactactgag aaatagtaat gacttctaca aatgcaaggg
     4501 tcttaccctc ctctttccct taaacaccct cccttttcct tagaccccgt ttttgccatc
     4561 ccccaaatgt gtggtatggt gaaactaatc ccctgaatgt gaattgctat ccttattgcc
     4621 ctattaaaga agagccagct ggtatattgt caggaagcac tatttaaaat gtgaactgtt
     4681 atagagtaaa taaataaata ctctacagga a
//
