LOCUS       NM_001321920            2735 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens family with sequence similarity 219 member B
            (FAM219B), transcript variant 2, mRNA.
ACCESSION   NM_001321920 XM_005254564
VERSION     NM_001321920.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2735)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2735)
  AUTHORS   Hattori,A., Okumura,K., Nagase,T., Kikuno,R., Hirosawa,M. and
            Ohara,O.
  TITLE     Characterization of long cDNA clones from human adult spleen
  JOURNAL   DNA Res 7 (6), 357-366 (2000)
   PUBMED   11214971
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125435.8 and BC064575.1.
            
            On May 31, 2019 this sequence version replaced NM_001321920.1.
            
            Transcript Variant: This variant (2), along with variants 1 and 3,
            encodes isoform a.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC064575.1, SRR1660805.193488.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-14                AC125435.8         47264-47277
            15-2735             BC064575.1         1-2721
FEATURES             Location/Qualifiers
     source          1..2735
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q24.1-q24.2"
     gene            1..2735
                     /gene="FAM219B"
                     /gene_synonym="C15orf17"
                     /note="family with sequence similarity 219 member B"
                     /db_xref="GeneID:57184"
                     /db_xref="HGNC:HGNC:24695"
     exon            1..265
                     /gene="FAM219B"
                     /gene_synonym="C15orf17"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..648
                     /gene="FAM219B"
                     /gene_synonym="C15orf17"
                     /note="isoform a is encoded by transcript variant 2;
                     uncharacterized protein C15orf17; protein FAM219B"
                     /codon_start=1
                     /product="protein FAM219B isoform a"
                     /protein_id="NP_001308849.1"
                     /db_xref="CCDS:CCDS32295.1"
                     /db_xref="GeneID:57184"
                     /db_xref="HGNC:HGNC:24695"
                     /translation="MATAEPSGRALRLSTPGPRPSGARDRAPGAAGPPSGQIGNRALR
                     LGERTPAAVEKRGPYMVTRAPSIQAKLQKHRDLAKAVLRRKGMLGASPNRPDSSGKRS
                     VKFNKGYTALSQSPDENLVSLDSDSDGELGSRYSSGYSSAEQVNQDVSRQLLQDGYHL
                     DEIPDDEDLDLIPPKPMASSTCSCCWCCLGDSSSCTLQ"
     exon            266..353
                     /gene="FAM219B"
                     /gene_synonym="C15orf17"
                     /inference="alignment:Splign:2.1.0"
     exon            354..431
                     /gene="FAM219B"
                     /gene_synonym="C15orf17"
                     /inference="alignment:Splign:2.1.0"
     exon            432..480
                     /gene="FAM219B"
                     /gene_synonym="C15orf17"
                     /inference="alignment:Splign:2.1.0"
     exon            481..663
                     /gene="FAM219B"
                     /gene_synonym="C15orf17"
                     /inference="alignment:Splign:2.1.0"
     exon            664..2735
                     /gene="FAM219B"
                     /gene_synonym="C15orf17"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2717..2722
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM219B"
                     /gene_synonym="C15orf17"
                     /note="hexamer: AATAAA"
     polyA_site      2735
                     /gene="FAM219B"
                     /gene_synonym="C15orf17"
                     /note="major polyA site"
ORIGIN      
        1 actctttcgc cacgggcggg gttgcaccat ccggcagggc ggggcccggc catggcgacc
       61 gcggagccca gcgggcgcgc gttgcggttg tctaccccgg gaccccggcc cagcggggct
      121 cgggaccgcg cgccgggagc tgcggggcca ccctccgggc agatcggtaa tagagccctc
      181 cgtctggggg agcgcacccc cgcggccgtg gaaaagcggg ggccatacat ggtgacgcgc
      241 gcaccctcca ttcaagccaa gctgcagaag caccgggacc tggccaaggc cgttctgcgg
      301 agaaaaggca tgctgggggc ctcgccgaac cgcccagact cttcagggaa aaggtcagtg
      361 aagtttaaca agggctatac tgctcttagc cagagtccag atgaaaacct ggtgtccctc
      421 gactctgaca gtgatgggga gctgggatcc agatactcct ccgggtattc atctgcagag
      481 caggtgaacc aggatgtgag ccggcagctg cttcaggatg ggtatcacct ggatgagatt
      541 ccagatgacg aggacttgga cctcatcccc cctaagccca tggcctcttc aacatgctcc
      601 tgctgctggt gctgtcttgg ggactcttct tcctgtaccc tccagtagac attaccctcc
      661 aaggttgcac ctgtctaact atgacaggga tcatagcagg ttgcttaatg atacagcagg
      721 atcctggctt ccagaatccc tggacctggg gcatccccaa ctggtccaac cgtccgggtg
      781 agtttagtga ttctggtttg cccttcccta gttagagaaa aactgctctg acatgttcat
      841 atttatttat ttgtatttcc ttggtctggg tgagtttctt cacccagtct ttgagctaaa
      901 gattaggtcg aaggtactgg ggctggcccc agaagcctgc agtttttatt attaccagca
      961 gagggagcta cagggagcag tccggtgcct tcctattgtt tactttttaa acttttgaga
     1021 agtagcaatg gactcgtgag agtgggtata cagctgtgtg ggctttgtcc tagactgagg
     1081 cttacagaca ggaagggtaa gagagaccta agccagctcc tagacccttg cctgaggaaa
     1141 tcagtccacc agtgtagagg gcctcccttc actccagcat ggaccattct attgccagat
     1201 tcttctggtc acagcatggg ccttactgga tactcaggat tgggctttaa gcagacctct
     1261 gggtgtgaca cagcctcttt cagcccccag cccaaacagc agaaataggc ataatttctg
     1321 ctgtgacacc ccctacccac aaattggaga gtatatcttg ctatactcta taccaagcct
     1381 ctttctagaa tttttccaac aggttttgtt ttgttttttg gcttaactca gaaccatggt
     1441 gagcgttctg ctttgttttg ttggagacag ggtctctgtc acccaggctg gagtgcagtg
     1501 gtgtaatcac agctcactgc agcctcaacc tcccaggccc aagcagtcct cccacatggt
     1561 gagctttgaa tgggcataga cagggttccc agcccaatag tcgggattgg ggtataggtt
     1621 ctacatggga aagtatccag tctcttgctt tactcagtgt cctgtgacca ccagaggcat
     1681 gagagggaca acacactctt ttcgctctac cacaaggggt gactagaaga tgagcaagtc
     1741 taataaaaag atacggcctt atttgttatt tgtctgacaa ccatccttac gatggtaatc
     1801 ctgtgagtgc ctgatggaca tctatctttg tgtttttctc aaaccatgga aggttgagag
     1861 gaatatacag tatctggggg ctgacttact ctactagcta ggagcatcac agcagagaga
     1921 taggacagag accagagtca tgccagcttg gggtcttggg aagagaggca gatggttact
     1981 ctgttctgga atgggactct gcagctctat gcagtggcca acattctgag cactttgtgc
     2041 aaatgcttgt agagctcaag aacatctcca tccagaaccc cttccccatc tgcagagacc
     2101 atgtccaggc ctttcttgtg tctgcagagg tgaagtgcac atgtggaaag ggatcaaatg
     2161 tagcacagtg taaagaaaga cagcaacaca ggtagaggga cccagtgtgt gctgggaggt
     2221 ggctgtggaa ggtaagtata gacctacatc tctgttgggg aggtggtcag ggcagaatgg
     2281 cctgggtgtt tagcagcttc taggggtgag ggtggcagga ccccaaaacc aaggccctct
     2341 gcatcgttgt tgtaataatc agctctggca tattcagctg caactgtccc tgaagaagag
     2401 gtttctgagc tggctgaccc catgtaggag ggtgttacct tgtagaaaaa gctggaggga
     2461 cctggtggga cagtgcagtg aggcagggta gaaatggtca gttgtttagg gccagtggcc
     2521 acataccaaa ataccaccaa tgtgcccagg gccaaactgc cttaattctg agtgctgtgt
     2581 gttctgcagg tgacagtttc ctgaggagag gggtgtatcc aggcttacct cccagcagga
     2641 gtggtaccat atggtgttta tgtactactc tatagaactc ttggcttgca cttctacagc
     2701 tctgtacatt tataagaata aatgcaatca cacta
//
